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What is EBM?
Critical Appraisal
of
the Literature
Statistics
and Trial Design
Systematic Reviews
EBM in Critical
Care
EBM Groups on
the Web
EBM Databases
MEDLINE Search
Strategies
Pediatric and General
Online Journal Clubs,
Teaching
Resources &
Tutorials
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Evidence-Based Medicine in Critical
Care
IntensiveCare.com:
tutorials, evidence alerts, research networks, information systems,
and more.
The
PedsCCM Evidence-Based Journal Club: Peer-reviewed critical analyses
of clinical trials pertinent to pediatric critical care medicine
- Examples include:
- Schindler MB, Bohn D, Cox PN, McCrindle BW, Jarvis A, Edmonds
J,
Barker, G. Outcome of out-of-hospital cardiac or respiratory arrest
in children. N Engl J Med 1996; 333:1473-9.
[abstract]
Critical Appraisal by A. Randolph (Posted 3/17/97)
- Raad D, Darouiche ER, Dupuis J. Central venous catheters coated
with
minocycline and rifampin for the prevention of catheter-related
colonization and bloodstream infections. Ann Intern Med
1997;127:267-274. [abstract]
Critical
Appraisal by S. Schexnayder (Posted 1/29/98)
From the Evidence Based Critical Care Medicine series in Critical
Care Medicine:
- Evidence based critical care medicine; what is it and what can it
do for us? Evidence Based Medicine in Critical Care Group. Cook DJ,
Sibbald WJ, Vincent JL, Cerra FB. Crit Care Med 1996; 24:334-337.
[abstract]
- How to keep up with the critical care literature and avoid being
buried alive. Cook DJ, Meade MO, Fink MP. Crit Care Med 1996; 24:1757-1768.
[abstract]
- Evidence based medicine in critical care: will it take us over the
cutting edge? Niederman MS. Crit Care Med 1997;25:1448-1449. (editorial;
no abstract available)
- How to use diagnostic test articles in the intensive care unit:
diagnosing weanability using f/Vt. Jaeschke RZ, Meade MO, Guyatt GH,
Keenan SP, Cook DJ. Crit Care Med 1997; 25:1514-1521. [abstract]
- How to use an article on therapy or prevention: pneumonia prevention
using subglottic secretion drainage. Cook DJ, Hebert PC, Heyland DK,
Guyatt GH, Brun-Buisson C, Marshall JC, Russell J, Vincent JL, Sprung
CL, Rutledge F. Crit Care Med 1997; 25:1502-1513. [abstract]
- How to use articles about harm: the relationship between high tidal
volumes, ventilating pressures, and ventilator-induced lung injury.
Meade MO, Cook DJ, Kernerman P, Bernard G. Crit Care Med 1997; 25:1915-1922.
[abstract]
- How to use practice guidelines in the intensive care unit: Diagnosis
and management of unstable angina.Cook DJ, Ellrodt AG, Calvin J, Levy
MM. Crit Care Med 1998 Mar;26(3):599-606. [abstract]
- How to use a review article: prophylactic endoscopic sclerotherapy
for esophageal varices. Cook DJ, Levy MM, Heyland DK. Crit Care
Med 1998; 26: 692-700. [abstract]
- Prognosis in the intensive care unit: finding accurate and useful
estimates for counseling patients. Randolph AG, Guyatt GH, Richardson
WS. Crit Care Med 1998; 26: 767-772. [abstract]
- Understanding articles comparing outcomes among intensive care units
to rate quality of care. Randolph AG, Guyatt GH, Carlet J. Crit Care
Med 1998; 26: 773-781. [abstract]
- Understanding articles describing clinical prediction tools. Randolph
AG, Guyatt GH, Calvin J, Doig G, Richardson WS. Crit Care Med 1998;
26: 1603-1612. [abstract]
- How to use the results of an economic evaluation. Heyland DK, Gafni
A, Kernerman P, et al. Crit Care Med 1999; 27: 1195-1202. [abstract]
- How to use articles about diagnostic technology: Gastric tonometry.
Keenan SP, Guyatt GH, Sibbald WJ, et al. Crit Care Med 1999;27:1726-1731.
[abstract]
Critical Care Clinics, July 1998 issue, is dedicated to evidence based
critical care. Articles include:
- Evidence-based medicine. A tool for enhancing critical care practice.
Cook DJ, Levy MM. Crit Care Clin 1998; 14:353-8. [abstract]
- Interpreting and using clinical trials. Doig GS. Crit Care Clin
1998; 14:513-525. [abstract]
- Evidence-based medicine and cost-effectiveness analysis. Chalfin
DB. Crit Care Clin 1998; 14:525-37. [abstract]
- with other management-specific articles cited throughout
the PedsCCM
File Cabinet
The status of EBM in Critical Care Medicine
- Villar J, Perez-Mendez L, Aguirre-Jaime A, Kacmarek RM. Why are physicians so skeptical about positive randomized controlled clinical trials in critical care medicine? Intensive Care Med. 2005 Feb;31(2):196-204 [citation]
![[new]](../GIFS/new.gif)
- Vincent JL. Evidence-Based Medicine in the ICU: Important Advances and Limitations. Chest 2004;126 592-600 [abstract]
How well do we understand our interventions?
- Ferreira F, Vincent JL, Brun-Buisson C et al. Doctors' perceptions of the effects of interventions tested in prospective, randomised, controlled, clinical trials: results of a survey of ICU physicians. Intensive Care Med, 2001; DOI 10.1007/s001340000749 [abstract, full-text for subscribers]
Generalizability of clinical trials
- Padkin A, Rowan K, Black N. Using high quality clinical databases to complement the results of randomised controlled trials: the case of recombinant human activated protein C. Br Med J 2001;323:923-926. [full-text]
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