PedsCCM: The Pediatric Critical Care Website:
The multidisciplinary and practical resource for Pediatric Critical Care on the Internet Peer reviewed original content integrated with links to selected web resources ... now 19 years old... thanks to everyone for your great support!..

What's NEW

April 2014

  • The Efficacy and Safety of Prone Positional Ventilation in Acute Respiratory Distress Syndrome: Updated Study-Level Meta-Analysis of 11 Randomized Controlled Trials. Lee JM, Bae W, Lee YJ, Cho YJ. Crit Care Med. 2014; 42:1252–1262 [abstract] (EB Journal Club)
  • A Multinational Study of Thromboprophylaxis Practice in Critically Ill Children. Faustino EV, Hanson S, Spinella PC, Tucci M, O'Brien SH, Nunez AR, Yung M, Truemper E, Qin L, Li S, Marohn K, Randolph AG; PROphylaxis against ThRombosis prACTice (PROTRACT) Study Investigators of the PALISI BloodNet. Crit Care Med. 2014; 42:1232–1240 [abstract] (EB Journal Club)
  • Early Bispectral Index and Sedation Requirements During Therapeutic Hypothermia Predict Neurologic Recovery Following Cardiac Arrest. Burjek NE, Wagner CE, Hollenbeck RD, Wang L, Yu C, McPherson JA, Billings FT 4th. Crit Care Med 2014; 42:1204–1212 [abstract] (EB Journal Club)
  • Outcomes and Complications of Intracranial Pressure Monitoring in Acute Liver Failure: A Retrospective Cohort Study. Karvellas CJ, Fix OK, Battenhouse H, Durkalski V, Sanders C, Lee WM; U.S. Acute Liver Failure Study Group. Crit Care Med. 2014; 42:1157–1167. [abstract] (EB Journal Club)
  • Chylothorax in infants and children. Tutor JD. Pediatrics. 2014 Apr;133(4):722-33. [abstract]
  • Health care-associated infection after red blood cell transfusion: a systematic review and meta-analysis. Rohde JM, Dimcheff DE, Blumberg N, Saint S, Langa KM, Kuhn L, Hickner A, Rogers MA. JAMA. 2014 Apr 2;311(13):1317-26. [abstract] (EB Journal Club)
  • Nutrition in the acute phase of critical illness. Casaer MP, Van den Berghe G. N Engl J Med. 2014 Mar 27;370(13):1227-36. [citation]
  • Enteral omega-3 fatty acid supplementation in adult patients with acute respiratory distress syndrome: a systematic review of randomized controlled trials with meta-analysis and trial sequential analysis. Zhu D, Zhang Y, Li S, Gan L, Feng H, Nie W. Intensive Care Med. 2014 Apr;40(4):504-12. [abstract] (EB Journal Club)

March 2014

  • A weekly update on influenza in the US from the CDC..
  • Kaukonen KM, Bailey M, Suzuki S, Pilcher D, Bellomo R. Mortality Related to Severe Sepsis and Septic Shock Among Critically Ill Patients in Australia and New Zealand, 2000-2012. JAMA. 2014 Mar 18. doi: 10.1001/jama.2014.2637. [abstract] (EB Journal Club)
  • Asfar P, Meziani F, Hamel JF, Grelon F, Megarbane B, Anguel N, Mira JP, Dequin PF, Gergaud S, Weiss N, Legay F, Le Tulzo Y, Conrad M, Robert R, Gonzalez F, Guitton C, Tamion F, Tonnelier JM, Guezennec P, Linden TV, Vieillard-Baron A, Mariotte E, Pradel G, Lesieur O, Ricard JD, HervĂ© F, Cheyron DD, Guerin C, Mercat A, Teboul JL, Radermacher P; the SEPSISPAM Investigators. High versus Low Blood-Pressure Target in Patients with Septic Shock. N Engl J Med. 2014 Mar 18. DOI: 10.1056/NEJMoa1312173 [abstract] (EB Journal Club)
  • The ProCESS Investigators. A Randomized Trial of Protocol-Based Care for Early Septic Shock. N Engl J Med. 2014 Mar 18; DOI: 10.1056/NEJMoa1401602 [abstract] (EB Journal Club)
  • Caironi P, Tognoni G, Masson S, Fumagalli R, Pesenti A, Romero M, Fanizza C, Caspani L, Faenza S, Grasselli G, Iapichino G, Antonelli M, Parrini V, Fiore G, Latini R, Gattinoni L; the ALBIOS Study Investigators. Albumin Replacement in Patients with Severe Sepsis or Septic Shock. N Engl J Med. 2014 March 18: DOI: 10.1056/NEJMoa1305727 [abstract] (EB Journal Club)
  • Gupta P, Yan K, Chow V, Dao DT, Gossett JM, Leong K, Franzon D, Halamek LP, Reddy S, Berg RA, Roth SJ, Nadkarni VM. Variability of Characteristics and Outcomes Following Cardiopulmonary Resuscitation Events in Diverse ICU Settings in a Single, Tertiary Care Children's Hospital*. Pediatr Crit Care Med. 2014 Mar;15(3):e128-41 [abstract] (EB Journal Club)
  • Marik PE. Enteral Nutrition in the Critically Ill: Myths and Misconceptions. Crit Care Med 2014; 42:962–969 [abstract]
  • Modem V, Thompson M, Gollhofer D, Dhar AV, Quigley R. Timing of Continuous Renal Replacement Therapy and Mortality in Critically Ill Children. Crit Care Med. 2014; 42:943–953 [abstract] (EB Journal Club)
  • Wong HR, Lindsell CJ, Pettilä V, Meyer NJ, Thair SA, Karlsson S, Russell JA, Fjell CD, Boyd JH, Ruokonen E, Shashaty MG, Christie JD, Hart KW, Lahni P, Walley KR. A Multibiomarker-Based Outcome Risk Stratification Model for Adult Septic Shock. Crit Care Med 2014; 42:781–789 [abstract] (EB Journal Club)
  • Beitler JR, Shaefi S, Montesi SB, Devlin A, Loring SH, Talmor D, Malhotra A. Prone positioning reduces mortality from acute respiratory distress syndrome in the low tidal volume era: a meta-analysis. Intensive Care Med. 2014 Mar;40(3):332-41 [abstract]
  • Carroll CL, Sala K, Fisher D, Zucker A. Pediatric Code Events: Does In-House Intensivist Coverage Improve Outcomes? Pediatr Crit Care Med. 2014; 15:250–257 [abstract; full-text (pdf:605K)]
  • Bangalore H, Ocampo EC, Rodriguez LM, Minard CG, Checchia PA, Heinle JS, Shekerdemian LS. Serum Cortisol and Early Postoperative Outcome After Stage-1 Palliation for Hypoplastic Left Heart Syndrome. Pediatr Crit Care Med. 2014; 15:211–218 [abstract]
  • Wolbrink TA, Kissoon N, Burns JP. The Development of an Internet-Based Knowledge Exchange Platform for Pediatric Critical Care Clinicians Worldwide. Pediatr Crit Care Med. 2014; 15:197–205. [abstract]
  • Magnus DC, Wilfond BS, Caplan AL. Accepting Brain Death. N Engl J Med. 2014 Feb 5. [Epub ahead of print] PMID: 24499177 [full-text]
  • Gostin LO. Legal and Ethical Responsibilities Following Brain Death: The McMath and Muñoz Cases. JAMA 2014;311(9):903-904 [citation]
  • PICUDoctor 4.0 - A PICU Cardiac Guide, which is now available for free of course at: (Software)
  • PICUTOOLS, by Michael Verive. Includes calculators, guidelines. graphs and more. (Software)

February 2014

  • Hunt BJ. Bleeding and coagulopathies in critical care. N Engl J Med. 2014 Feb 27;370(9):847-59. [citation]
  • Napolitano LM, Angus DC, Uyeki TM. Critically Ill Patients With Influenza A(H1N1)pdm09 Virus Infection in 2014. JAMA. Published online February 24, 2014. doi:10.1001/jama.2014.2116 [full-text]
  • Fitzgerald RK, Yu JC, Rajasekaran S, Curtis SE, Robertson DJ, Wincek JM, Blanton R, Sanfilippo DJ. Cost and safety of pediatric intensive care physician-placed broviac catheters. Pediatr Crit Care Med. 2014 Jan;15(1):71-6. [abstract] (EB Journal Club)
  • Fink EL, Berger RP, Clark RS, Watson RS, Angus DC, Richichi R, Panigrahy A, Callaway CW, Bell MJ, Kochanek PM. Serum biomarkers of brain injury to classify outcome after pediatric cardiac arrest*. Crit Care Med. 2014 Mar;42(3):664-74 [abstract] (EB Journal Club)
  • Traube C, Silver G, Kearney J, Patel A, Atkinson TM, Yoon MJ, Halpert S, Augenstein J, Sickles LE, Li C, Greenwald B. Cornell Assessment of Pediatric Delirium: A Valid, Rapid, Observational Tool for Screening Delirium in the PICU*. Crit Care Med. 2014 Mar;42(3):656-63. [abstract] (EB Journal Club)
  • Freeman CL, Bennett TD, Casper TC, Larsen GY, Hubbard A, Wilkes J, Bratton SL. Pediatric and neonatal extracorporeal membrane oxygenation: does center volume impact mortality?*. Crit Care Med. 2014 Mar;42(3):512-9. [abstract] (EB Journal Club)
  • Yager PH, Luginbuhl LM, Dekker JP. Case 6-2014 — A 35-Day-Old Boy with Fever, Vomiting, Mottled Skin, and Severe Anemia. N Engl J Med 2014; 370:753-762 [full-text (subscribers)] (Case Reports)
  • Animated videos of congenital heart defects from Cincinnati Children's Hospital Medical Center are here...
  • The AAP Section on Critical Care (SOCC) is pleased to announce availability of two small grants for young investigators for projects devoted to education in Pediatric Critical Care Medicine and outcomes of quality and safety initiatives in the PICU. Read more here... (Organizations)
  • Hassinger AB, Wald EL, Goodman DM. Early postoperative fluid overload precedes acute kidney injury and is associated with higher morbidity in pediatric cardiac surgery patients. Pediatr Crit Care Med. 2014 Feb;15(2):131-8. [abstract; full-text (pdf 505K)] (EB Journal Club)
  • Reade MC, Finfer S. Sedation and delirium in the intensive care unit. N Engl J Med. 2014 Jan 30;370(5):444-54 [citation]
  • Kalfon P, Giraudeau B, Ichai C, Guerrini A, Brechot N, Cinotti R, Dequin PF, Riu-Poulenc B, Montravers P, Annane D, Dupont H, Sorine M, Riou B; CGAO–REA Study Group. Tight computerized versus conventional glucose control in the ICU: a randomized controlled trial. Intensive Care Med. 2014 Feb;40(2):171-81 [abstract] (EB Journal Club)

January 2014

  • Gupta P, Green JW, Tang X, Gall CM, Gossett JM, Rice TB, Kacmarek RM, Wetzel RC. Comparison of High-Frequency Oscillatory Ventilation and Conventional Mechanical Ventilation in Pediatric Respiratory Failure. JAMA Pediatr. 2014;168(3):243-249 [abstract] (EB Journal Club)
  • Smith R, Rennie D. Evidence-Based Medicine—An Oral History JAMA. Published online January 21, 2014. doi:10.1001/jama.2013.286182 [full-text]
  • Adhikari NK, Dellinger RP, Lundin S, Payen D, Vallet B, Gerlach H, Joo Park K, Mehta S, Slutsky AS, Friedrich JO. Inhaled Nitric Oxide Does Not Reduce Mortality in Patients With Acute Respiratory Distress Syndrome Regardless of Severity: Systematic Review and Meta-Analysis. Crit Care Med 2014; 42:404–412. [abstract] (EB Journal Club)
  • Abulebda K, Cvijanovich NZ, Thomas NJ, Allen GL, Anas N, Bigham MT, Hall M, Freishtat RJ, Sen A, Meyer K, Checchia PA, Shanley TP, Nowak J, Quasney M, Weiss SL, Chopra A, Banschbach S, Beckman E, Lindsell CJ, Wong HR. Post-ICU Admission Fluid Balance and Pediatric Septic Shock Outcomes: A Risk-Stratified Analysis. Crit Care Med 2014; 42:397–403. [abstract] (EB Journal Club)
  • Knight LJ, Gabhart JM, Earnest KS, Leong KM, Anglemyer A, Franzon D. Improving Code Team Performance and Survival Outcomes: Implementation of Pediatric Resuscitation Team Training. Crit Care Med. 2014; 42:243–251 [abstract] (EB Journal Club)
  • Videos in Clinical Medicine: Ortega R, Connor C, Rodriguez G, Spencer C. Endotracheal Extubation. N Engl J Med 2014; 370:e4January 16, 2014DOI: 10.1056/NEJMvcm1300964 [video (subscribers only)]
  • Macrae D, Grieve R, Allen E, Sadique Z, Morris K, Pappachan J, Parslow R, Tasker RC and Elbourne D for the CHiP Investigators. A Randomized Trial of Hyperglycemic Control in Pediatric Intensive Care. N Engl J Med 2014;370:107-18. [abstract] (EB Journal Club)
  • Wang J, Xu E, Xiao Y. Isotonic Versus Hypotonic Maintenance IV Fluids in Hospitalized Children: A Meta-Analysis. Pediatrics 2014;133;105. [abstract] (EB Journal Club)
  • Ross PA, Newth CJ, Khemani RG. Accuracy of Pulse Oximetry in Children. Pediatrics 2014;133;22 [abstract]

December 2013

  • Bernal W, Wendon J. Acute liver failure. N Engl J Med 2013;369:2525-34. [citatiion]
  • Raj S, Killinger JS, Gonzalez JA, Lopez L. Myocardial Dysfunction in Pediatric Septic Shock. J Pediatr. 2013 Oct 18. pii: S0022-3476(13)01150-5. doi: 10.1016/j.jpeds.2013.09.027. [abstract]
  • Steingrub JS, Lagu T, Rothberg MB, Nathanson BH, Raghunathan K, Lindenauer PK. Treatment With Neuromuscular Blocking Agents and the Risk of In-Hospital Mortality Among Mechanically Ventilated Patients With Severe Sepsis* Crit Care Med. 2014 Jan;42(1):90-96. [abstract] (EB Journal Club)
  • Krag M, Perner A, Wetterslev J, Wise MP, Hylander Møller M. Stress ulcer prophylaxis versus placebo or no prophylaxis in critically ill patients : A systematic review of randomised clinical trials with meta-analysis and trial sequential analysis. Intensive Care Med. 2014 Jan;40(1):11-22. [abstract] (EB Journal Club)
  • Edwards JD, Lucas AR, Stone PW, Boscardin WJ, Dudley RA. Frequency, Risk Factors, and Outcomes of Early Unplanned Readmissions to PICUs. Crit Care Med. 2013; 41:2773–2783 [abstract] (EB Journal Club)
  • Mourvillier B, Tubach F, van de Beek D, Garot D, Pichon N, Georges H, Lefevre LM, Bollaert PE, Boulain T, Luis D, Cariou A, Girardie P, Chelha R, Megarbane B, Delahaye A, Chalumeau-Lemoine L, Legriel S, Beuret P, Brivet F, Bruel C, Camou F, Chatellier D, Chillet P, Clair B, Constantin JM, Duguet A, Galliot R, Bayle F, Hyvernat H, Ouchenir K, Plantefeve G, Quenot JP, Richecoeur J, Schwebel C, Sirodot M, Esposito-Farèse M, Le Tulzo Y, Wolff M. Induced Hypothermia in Severe Bacterial Meningitis: A Randomized Clinical Trial. JAMA. 2013;310(20):2174-2183. [abstract] (EB Journal Club)
  • Luu R, Dewitt PE, Reiter PD, Dobyns EL, Kaufman J. Hyponatremia in Children with Bronchiolitis Admitted to the Pediatric Intensive Care Unit Is Associated with Worse Outcomes. J Pediatr 2013;163:1652-6. [abstract] (EB Journal Club)
  • Nielsen N, Wetterslev J, Cronberg T, Erlinge D, Gasche Y, Hassager C, Horn J, Hovdenes J, Kjaergaard J, Kuiper M, Pellis T, Stammet P, Wanscher M, Wise MP, Aneman A, Al-Subaie N, Boesgaard S, Bro-Jeppesen J, Brunetti I, Bugge JF, Hingston CD, Juffermans NP, Koopmans M, Køber L, Langørgen J, Lilja G, Møller JE, Rundgren M, Rylander C, Smid O, Werer C, Winkel P, Friberg H; the TTM Trial Investigators. Targeted Temperature Management at 33°C versus 36°C after Cardiac Arrest. N Engl J Med. 2013 Nov 17. [Epub ahead of print] PMID: 24237006 [abstract] (EB Journal Club)

November 2013

  • Kim F, Nichol G, Maynard C, Hallstrom A, Kudenchuk PJ, Rea T, Copass MK, Carlbom D, Deem S, Longstreth WT Jr, Olsufka M, Cobb LA. Effect of Prehospital Induction of Mild Hypothermia on Survival and Neurological Status Among Adults With Cardiac Arrest: A Randomized Clinical Trial. JAMA. 2013 Nov 17. doi: 10.1001/jama.2013.282173 [abstract] (EB Journal Club)
  • Farris RW, Weiss NS, Zimmerman JJ. Functional outcomes in pediatric severe sepsis: further analysis of the researching severe sepsis and organ dysfunction in children: a global perspective trial*. Pediatr Crit Care Med. 2013 Nov;14(9):835-42. [abstract; full-text (pdf:555K)] (EB Journal Club)
  • De Luca D, Piastra M, Chidini G, Tissieres P, Calderini E, Essouri S, Medina Villanueva A, Vivanco Allende A, Pons-Odena M, Perez-Baena L, Hermon M, Tridente A, Conti G, Antonelli M, Kneyber M; Respiratory Section of the European Society for Pediatric Neonatal Intensive Care (ESPNIC). The use of the Berlin definition for acute respiratory distress syndrome during infancy and early childhood: multicenter evaluation and expert consensus. Intensive Care Med. 2013 Dec;39(12):2083-91 [abstract]
  • Bonafide CP, Localio AR, Roberts KE, Nadkarni VM, Weirich CM, Keren R. Impact of Rapid Response System Implementation on Critical Deterioration Events in Children. JAMA Pediatr. 2013 Nov 11. doi: 10.1001/jamapediatrics.2013.3266 [abstract]
  • Topjian AA, Clark AE, Casper TC, Berger JT, Schleien CL, Dean JM, Moler FW; for the Pediatric Emergency Care Applied Research Network. Early Lactate Elevations Following Resuscitation From Pediatric Cardiac Arrest Are Associated With Increased Mortality* Pediatr Crit Care Med. 2013 Oct;14(8):e380-e387. [abstract; full-text (613K pdf)] (EB Journal Club)
  • Axelrod DM, Klugman D, Wright GE, Chang A, Bronicki R, Roth SJ; Board Members of the Pediatric Cardiac Intensive Care Society. One hundred useful references in pediatric cardiac intensive care: the 2012 update. Pediatr Crit Care Med. 2013 Oct;14(8):770-85. [abstract]
  • Michiels EA, Dumas F, Quan L, Selby L, Copass M, Rea T. Long-Term Outcomes Following Pediatric Out-of-Hospital Cardiac Arrest*. Pediatr Crit Care Med. 2013 Oct;14(8):755-60. [abstract] (EB Journal Club)
  • Vincent JL, De Backer D. Circulatory shock. N Engl J Med. 2013 Oct 31;369(18):1726-34 [citation]

October 2013

  • Annane D, Siami S, Jaber S, Martin C, Elatrous S, Declère AD, Preiser JC, Outin H, TrochĂ© G, Charpentier C, Trouillet JL, Kimmoun A, Forceville X, Darmon M, Lesur O, RĂ©gnier J, Abroug F, Berger P, Clech C, Cousson J, Thibault L, Chevret S; for the CRISTAL Investigators. Effects of Fluid Resuscitation With Colloids vs Crystalloids on Mortality in Critically Ill Patients Presenting With Hypovolemic Shock: The CRISTAL Randomized Trial. JAMA. 2013 Oct 9. doi: 10.1001/jama.2013.280502. [abstract] (EB Journal Club)
  • Harris AD, Pineles L, Belton B, Johnson JK, Shardell M, Loeb M, Newhouse R, Dembry L, Braun B, Perencevich EN, Hall KK, Morgan DJ; and the Benefits of Universal Glove and Gown (BUGG) Investigators, Shahryar SK, Price CS, Gadbaw JJ, Drees M, Kett DH, Muñoz-Price LS, Jacob JT, Herwaldt LA, Sulis CA, Yokoe DS, Maragakis L, Lissauer ME, Zervos MJ, Warren DK, Carver RL, Anderson DJ, Calfee DP, Bowling JE, Safdar N. Universal Glove and Gown Use and Acquisition of Antibiotic-Resistant Bacteria in the ICU: A Randomized Trial. JAMA. 2013 Oct 4. doi: 10.1001/jama.2013.277815. [abstract] (EB Journal Club)
  • Morelli A, Ertmer C, Westphal M, Rehberg S, Kampmeier T, Ligges S, Orecchioni A, D'Egidio A, D'Ippoliti F, Raffone C, Venditti M, Guarracino F, Girardis M, Tritapepe L, Pietropaoli P, Mebazaa A, Singer M. Effect of Heart Rate Control With Esmolol on Hemodynamic and Clinical Outcomes in Patients With Septic Shock: A Randomized Clinical Trial. JAMA. 2013 Oct 9. doi: 10.1001/jama.2013.278477 [abstract] (EB Journal Club)
  • Mourvillier B, Tubach F, van de Beek D, Garot D, Pichon N, Georges H, Lefevre LM, Bollaert PE, Boulain T, Luis D, Cariou A, Girardie P, Chelha R, Megarbane B, Delahaye A, Chalumeau-Lemoine L, Legriel S, Beuret P, Brivet F, Bruel C, Camou F, Chatellier D, Chillet P, Clair B, Constantin JM, Duguet A, Galliot R, Bayle F, Hyvernat H, Ouchenir K, Plantefeve G, Quenot JP, Richecoeur J, Schwebel C, Sirodot M, Esposito-Farèse M, Le Tulzo Y, Wolff M. Induced Hypothermia in Severe Bacterial Meningitis: A Randomized Clinical Trial. JAMA. 2013 Oct 8. doi: 10.1001/jama.2013.280506. [abstract] (EB Journal Club)
  • de Gast-Bakker DH, de Wilde RB, Hazekamp MG, Sojak V, Zwaginga JJ, Wolterbeek R, de Jonge E, Gesink-van der Veer BJ. Safety and effects of two red blood cell transfusion strategies in pediatric cardiac surgery patients: a randomized controlled trial. Intensive Care Med. 2013 Nov;39(11):2011-9. [abstract] (EB Journal Club)

September 2013

  • The really new PICU List (2013) is operational here.... A user's guide is here...
  • Wilcox ME, Chong CA, Niven DJ, Rubenfeld GD, Rowan KM, Wunsch H, Fan E. Do Intensivist Staffing Patterns Influence Hospital Mortality Following ICU Admission? A Systematic Review and Meta-Analyses* Crit Care Med. 2013 Oct;41(10):2253-2274. [abstract] (EB Journal Club)
  • McShane P, Draper ES, McKinney PA, McFadzean J, Parslow RC; Paediatric Intensive Care Audit Network (PICANet). Effects of Out-of-Hours and Winter Admissions and Number of Patients per Unit on Mortality in Pediatric Intensive Care. J Pediatr. 2013;163:1039-44. [abstract] (EB Journal Club)
  • Evidence-based Medicine meets YouTube! Enjoy this clip: Viva La Evidence
  • Zhou F, Peng Z, Murugan R, Kellum JA. Blood purification and mortality in sepsis: a meta-analysis of randomized trials*. Crit Care Med 2013; 41:2209–2220. [abstract] (EB Journal Club)
  • Straney L, Clements A, Parslow RC, Pearson G, Shann F, Alexander J, Slater A; for the ANZICS Paediatric Study Group and the Paediatric Intensive Care Audit Network. Paediatric Index of Mortality 3: An Updated Model for Predicting Mortality in Pediatric Intensive Care. Pediatr Crit Care Med. 2013; 14:673–681 [abstract]
  • Willson DF, Thomas NJ, Tamburro R, Truemper E, Truwit J, Conaway M, Traul C, Egan EE; Pediatric Acute Lung and Sepsis Investigators Network. The Relationship of Fluid Administration to Outcome in the Pediatric Calfactant in Acute Respiratory Distress Syndrome Trial* Pediatr Crit Care Med. 2013 Sep;14(7):666-672. [abstract; full-text (pdf: 750K)] (EB Journal Club)
  • Willson DF, Thomas NJ, Tamburro R, Truemper E, Truwit J, Conaway M, Traul C, Egan EE; Pediatric Acute Lung and Sepsis Investigators Network. Pediatric Calfactant in Acute Respiratory Distress Syndrome Trial* Pediatr Crit Care Med. 2013 Sep;14(7):657-665. [abstract] (EB Journal Club)
  • Liu W, Zuo Z, Ma R, Zhang X. Effect of Mechanical Cleaning of Endotracheal Tubes With Sterile Urethral Catheters to Reduce Biofilm Formation in Ventilator Patients. Pediatr Crit Care Med. 14:e338–e343 [abstract] (EB Journal Club)
  • The September 2013 WFPICCS Newsletter is here... (Organizations)
  • Kamps MJ, Horn J, Oddo M, Fugate JE, Storm C, Cronberg T, Wijman CA, Wu O, Binnekade JM, Hoedemaekers CW. Prognostication of neurologic outcome in cardiac arrest patients after mild therapeutic hypothermia: a meta-analysis of the current literature. Intensive Care Med. 2013 Oct;39(10):1671-82 [abstract] (EB Journal Club)
  • Schmidt M, Zogheib E, RozĂ© H, Repesse X, Lebreton G, Luyt CE, Trouillet JL, BrĂ©chot N, Nieszkowska A, Dupont H, Ouattara A, Leprince P, Chastre J, Combes A. The PRESERVE mortality risk score and analysis of long-term outcomes after extracorporeal membrane oxygenation for severe acute respiratory distress syndrome. Intensive Care Med. 2013 Oct;39(10):1704-13. [abstract] (EB Journal Club)
  • Kim YA, Ha EJ, Jhang WK, Park SJ. Early blood lactate area as a prognostic marker in pediatric septic shock. Intensive Care Med. 2013 Oct;39(10):1818-23 [abstract] (EB Journal Club)

August 2013

  • Vincent JL, Ramesh MK, Ernest D, Larosa SP, Pachl J, Aikawa N, Hoste E, Levy H, Hirman J, Levi M, Daga M, Kutsogiannis DJ, Crowther M, Bernard GR, Devriendt J, Puigserver JV, Blanzaco DU, Esmon CT, Parrillo JE, Guzzi L, Henderson SJ, Pothirat C, Mehta P, Fareed J, Talwar D, Tsuruta K, Gorelick KJ, Osawa Y, Kaul I. A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study to Evaluate the Safety and Efficacy of Recombinant Human Soluble Thrombomodulin, ART-123, in Patients With Sepsis and Suspected Disseminated Intravascular Coagulation* Crit Care Med. 2013; 41:2070–2079 [abstract] (EB Journal Club)
  • Ghuman AK, Newth CJ, Khemani RG. Impact of Gender on Sepsis Mortality and Severity of Illness for Prepubertal and Postpubertal Children. J Pediatr. 2013;163:835-40. [abstract] (EB Journal Club)
  • Deep A, Goonasekera CD, Wang Y, Brierley J. Evolution of haemodynamics and outcome of fluid-refractory septic shock in children. Intensive Care Med. 2013 Sep;39(9):1602-9 [abstract] (EB Journal Club)
  • Joannes-Boyau O, HonorĂ© PM, Perez P, Bagshaw SM, Grand H, Canivet JL, Dewitte A, Flamens C, Pujol W, Grandoulier AS, Fleureau C, Jacobs R, Broux C, Floch H, Branchard O, Franck S, RozĂ© H, Collin V, Boer W, Calderon J, Gauche B, Spapen HD, Janvier G, Ouattara A. High-volume versus standard-volume haemofiltration for septic shock patients with acute kidney injury (IVOIRE study): a multicentre randomized controlled trial. Intensive Care Med. 2013 Sep;39(9):1535-46. [abstract] (EB Journal Club)
  • Adelson PD, Wisniewski SR, Beca J, Brown SD, Bell M, Muizelaar JP, Okada P, Beers SR, Balasubramani GK, Hirtz D; Paediatric Traumatic Brain Injury Consortium. Comparison of hypothermia and normothermia after severe traumatic brain injury in children (Cool Kids): a phase 3, randomised controlled trial. Lancet Neurol. 2013 Jun;12(6):546-53. [abstract] (EB Journal Club)
  • picudoctor is a web-based resource for pediatric cardiac critical care, from guidelines to calculators. Now with an iPhone/iPad app available via iTunes. And for Android here.... From Marc Anders, Royal Children's Hospital, Melbourne, Australia. (updated August 1, 2013 )
  • Health and Medical Sciences Open Courseware from the Open Education Database

July 2013

  • From Satyanarayan Hegde MD, University of Florida:
    • I am conducting an online survey of various providers (pediatric pulmonologists, intensivists & hospitalists) on the use of High Flow Nasal Cannula (HFNC) therapy. This is an IRB approved research questionnaire and would take only 5 minutes or less to complete. The survey is here. (Clinical Research: Surveys)
  • Foster CB, Spaeder MC, McCarter RJ, Cheng YI, Berger JT. The use of near-infrared spectroscopy during an extubation readiness trial as a predictor of extubation outcome. Pediatr Crit Care Med. 2013 Jul;14(6):587-92. [abstract; full-text (pdf; 540K)] (EB Journal Club)
  • Wessel DL, Berger F, Li JS, Dähnert I, Rakhit A, Fontecave S, Newburger JW; CLARINET Investigators. Clopidogrel in infants with systemic-to-pulmonary-artery shunts. N Engl J Med. 2013 Jun 20;368(25):2377-84. [abstract] (EB Journal Club)
  • Czaja AS, Hosokawa PW, Henderson WG. Unscheduled Readmissions to the PICU: Epidemiology, Risk Factors, and Variation Among Centers. Pediatr Crit Care Med. 2013 Jul;14(6):571-9. [abstract] (EB Journal Club)
  • Claassen J, Taccone FS, Horn P, Holtkamp M, Stocchetti N, Oddo M. Recommendations on the use of EEG monitoring in critically ill patients: consensus statement from the neurointensive care section of the ESICM. Intensive Care Med. 2013 Aug;39(8):1337-1351. [abstract]
  • A Systematic Review of Evidence-Informed Practices for Patient Care Rounds in the ICU. Lane D, Ferri M, Lemaire J, McLaughlin K, Stelfox HT. Crit Care Med. 2013; 41(8):2015-2029. [abstract]
  • Mentzelopoulos SD, Malachias S, Chamos C, Konstantopoulos D, Ntaidou T, Papastylianou A, Kolliantzaki I, Theodoridi M, Ischaki H, Makris D, Zakynthinos E, Zintzaras E, Sourlas S, Aloizos S, Zakynthinos SG. Vasopressin, steroids, and epinephrine and neurologically favorable survival after in-hospital cardiac arrest: a randomized clinical trial. JAMA. 2013 Jul 17;310(3):270-9 [abstract] (EB Journal Club)

June 2013

  • Marik PE, Cavallazzi R. Does the central venous pressure predict fluid responsiveness? An updated meta-analysis and a plea for some common sense*. Crit Care Med. 2013 Jul;41(7):1774-81 [abstract] (EB Journal Club)
  • Anderson CS, Heeley E, Huang Y, Wang J, Stapf C, Delcourt C, Lindley R, Robinson T, Lavados P, Neal B, Hata J, Arima H, Parsons M, Li Y, Wang J, Heritier S, Li Q, Woodward M, Simes RJ, Davis SM, Chalmers J; the INTERACT2 Investigators. Rapid Blood-Pressure Lowering in Patients with Acute Intracerebral Hemorrhage. N Engl J Med. 2013;368:2355-65. [abstract] (EB Journal Club)
  • Leteurtre S, Duhamel A, Salleron J, Grandbastien B, Lacroix J, Leclerc F; on behalf of the Groupe Francophone de RĂ©animation et d’Urgences PĂ©diatriques (GFRUP).PELOD-2: An Update of the PEdiatric Logistic Organ Dysfunction Score. Crit Care Med. 2013; 41(7):1761-1773. [abstract] (EB Journal Club)
  • Sarnaik AA, Clark JA, Meert KL, Sarnaik AP. Views of Pediatric Intensive Care Physicians on the Ethics of Organ Donation After Cardiac Death. Crit Care Med. 2013; 41(7):1733-1744. [abstract]
  • Volpicelli G, Lamorte A, Tullio M, Cardinale L, Giraudo M, Stefanone V, Boero E, Nazerian P, Pozzi R, Frascisco MF. Point-of-care multiorgan ultrasonography for the evaluation of undifferentiated hypotension in the emergency department. Intensive Care Med. 2013 Jul;39(7):1290-8. [abstract] (EB Journal Club)
  • Kirkpatrick AW, Roberts DJ, De Waele J, Jaeschke R, Malbrain ML, De Keulenaer B, Duchesne J, Bjorck M, Leppaniemi A, Ejike JC, Sugrue M, Cheatham M, Ivatury R, Ball CG, Reintam Blaser A, Regli A, Balogh ZJ, D'Amours S, Debergh D, Kaplan M, Kimball E, Olvera C; Pediatric Guidelines Sub-Committee for the World Society of the Abdominal Compartment Syndrome. Intra-abdominal hypertension and the abdominal compartment syndrome: updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome. Intensive Care Med. 2013 Jul;39(7):1190-206. [abstract]
  • Huang SS, Septimus E, Kleinman K, Moody J, Hickok J, Avery TR, Lankiewicz J, Gombosev A, Terpstra L, Hartford F, Hayden MK, Jernigan JA, Weinstein RA, Fraser VJ, Haffenreffer K, Cui E, Kaganov RE, Lolans K, Perlin JB, Platt R; the CDC Prevention Epicenters Program; the AHRQ DECIDE Network and Healthcare-Associated Infections Program. Targeted versus Universal Decolonization to Prevent ICU Infection. N Engl J Med. 2013; 365 (24): 2255-2265. [abstract] (EB Journal Club)
  • Menon K, McNally JD, Choong K, Ward RE, Lawson ML, Ramsay T, Wong HR. A Survey of Stated Physician Practices and Beliefs on the Use of Steroids in Pediatric Fluid and/or Vasoactive Infusion-Dependent Shock. Pediatr Crit Care Med. 2013; 14(5):462-466. [abstract, full-text (pdf: 491K)]
  • Pollack MM, Dean JM, Butler J, Holubkov R, Doctor A, Meert KL, Newth CJ, Berg RA, Moler F, Dalton H, Wessel DL, Berger J, Harrison RE, Carcillo JA, Shanley TP, Nicholson CE. The Ideal Time Interval for Critical Care Severity-of-Illness Assessment. Pediatr Crit Care Med. 2013; 14(5):448-453. [abstract]
  • PICU Question of the Day for iPhone/iPad, by William Ma and Riad Lutfi, Indiana University (iTunes store link) (Software)
  • Kerlin MP, Small DS, Cooney E, Fuchs BD, Bellini LM, Mikkelsen ME, Schweickert WD, Bakhru RN, Gabler NB, Harhay MO, Hansen-Flaschen J, Halpern SD. A Randomized Trial of Nighttime Physician Staffing in an Intensive Care Unit. N Engl J Med. 2013 DOI: 10.1056/NEJMoa1302854 [abstract] (EB Journal Club)
  • picudoctor is a web-based resource for pediatric cardiac critical care, from guidelines to calculators. Now with an iPhone/iPad app available via iTunes. From Marc Anders, Royal Children's Hospital, Melbourne, Australia. (Software)
  • Murad MH, Montori VM. Synthesizing evidence: shifting the focus from individual studies to the body of evidence. JAMA. 2013 Jun 5;309(21):2217-8. [citation] (EB Resources)

May 2013

  • The University of Rochester Divisions of Pediatric Critical Care and Pediatric Otolaryngology are conducting a survey evaluating attitudes regarding post-tonsillectomy intensive care admission among pediatric otolaryngologists and pediatric intensivists. Please read more here... (Clinical Research)
  • Alhazzani W, Jacobi J, Sindi A, Hartog C, Reinhart K, Kokkoris S, Gerlach H, Andrews P, Drabek T, Manzanares W, Cook DJ, Jaeschke RZ. The Effect of Selenium Therapy on Mortality in Patients With Sepsis Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials* Crit Care Med. 2013 Jun;41(6):1555-1564. [abstract] (EB Journal Club)
  • Bennett KS, Clark AE, Meert KL, Topjian AA, Schleien CL, Shaffner DH, Dean JM, Moler FW; for the Pediatric Emergency Care Medicine Applied Research Network. Early Oxygenation and Ventilation Measurements After Pediatric Cardiac Arrest: Lack of Association With Outcome. Crit Care Med. 2013 Jun;41(6):1534-1542. [abstract] (EB Journal Club)
  • GuĂ©rin C, Reignier J, Richard JC, Beuret P, Gacouin A, Boulain T, Mercier E, Badet M, Mercat A, Baudin O, Clavel M, Chatellier D, Jaber S, Rosselli S, Mancebo J, Sirodot M, Hilbert G, Bengler C, Richecoeur J, Gainnier M, Bayle F, Bourdin G, Leray V, Girard R, Baboi L, Ayzac L; the PROSEVA Study Group. Prone Positioning in Severe Acute Respiratory Distress Syndrome. N Engl J Med. 2013 May 20. DOI: 10.1056/NEJMoa1214103 [abstract] (EB Journal Club)
  • Berger JT, Carcillo JA, Shanley TP, Wessel DL, Clark A, Holubkov R, Meert KL, Newth CJ, Berg RA, Heidemann S, Harrison R, Pollack M, Dalton H, Harvill E, Karanikas A, Liu T, Burr JS, Doctor A, Dean JM, Jenkins TL, Nicholson CE; for the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Collaborative Pediatric Critical Care Research Network (CPCCRN). Critical Pertussis Illness in Children: A Multicenter Prospective Cohort Study* Pediatr Crit Care Med. 2013 May;14(4):356-365. [abstract; full-text (pdf; 590K)] (File Cabinet, EB Journal Club)
  • Thomas NJ, Jouvet P, Willson D. Acute Lung Injury in Children-Kids Really Aren't Just "Little Adults" Pediatr Crit Care Med. 2013 May;14(4):429-432. [abstract] (File Cabinet)
  • Edwards JD, Houtrow AJ, Vasilevskis EE, Dudley RA, Okumura MJ. Multi-institutional Profile of Adults Admitted to Pediatric Intensive Care Units. JAMA Pediatr. 2013;167(5):436 [abstract] (File Cabinet, EB Journal Club)
  • The April 2013 CoPS (Council on Pediatric Subspecialties) update is now available here... (pdf; 112K) (Organizations)
  • The International Children’s Heart Foundation is seeking to expand its team of Staff Intensivists staff to support the development of pediatric cardiac programs in Benghazi Libya, and in Nassiriya Iraq. Read more... (pdf; 268K) (International Child Health)

April 2013

  • Lazaridis C, Neyens R, Bodle J, Desantis SM. High-osmolarity saline in neurocritical care: systematic review and meta-analysis*. Crit Care Med. 2013 May;41(5):1353-60. [abstract] (File Cabinet, EB Journal Club)
  • Maekawa K, Tanno K, Hase M, Mori K, Asai Y. Extracorporeal Cardiopulmonary Resuscitation for Patients With Out-of-Hospital Cardiac Arrest of Cardiac Origin: A Propensity-Matched Study and Predictor Analysis*. Crit Care Med. 2013 May;41(5):1186-96. [abstract] (File Cabinet, EB Journal Club)
  • Floh AA, La Rotta G, Wermelt JZ, Bastero-Miñón P, Sivarajan VB, Humpl T. Validation of a new method based on ultrasound velocity dilution to measure cardiac output in paediatric patients. Intensive Care Med. 2013 May;39(5):926-33. [abstract] (File Cabinet, EB Journal Club)
  • Jouvet PA, Payen V, Gauvin F, Emeriaud G, Lacroix J. Weaning children from mechanical ventilation with a computer-driven protocol: a pilot trial. Intensive Care Med. 2013 May;39(5):919-25. [abstract] (File Cabinet, EB Journal Club)
  • Vaahersalo J, Hiltunen P, Tiainen M, Oksanen T, Kaukonen KM, Kurola J, Ruokonen E, Tenhunen J, Ala-Kokko T, Lund V, Reinikainen M, Kiviniemi O, Silfvast T, Kuisma M, Varpula T, Pettilä V; FINNRESUSCI Study Group. Therapeutic hypothermia after out-of-hospital cardiac arrest in Finnish intensive care units: the FINNRESUSCI study. Intensive Care Med. 2013 May;39(5):826-37. [abstract] (File Cabinet, EB Journal Club)
  • Drazen JM, Solomon CG, Greene MF. Informed Consent and SUPPORT. N Engl J Med. 2013 April 17, 2013DOI: 10.1056/NEJMe1304996 [abstract]
  • Hunt DP, Muse VV, Pitman MB.Case 12-2013. An 18-Year-Old Woman with Pulmonary Infiltrates and Respiratory Failure N Engl J Med. 2013 Apr 18;368(16):1537-1545. [abstract] (Case Reports)
  • Heyland D, Muscedere J, Wischmeyer PE, Cook D, Jones G, Albert M, Elke G, Berger MM, Day AG; the Canadian Critical Care Trials Group. A Randomized Trial of Glutamine and Antioxidants in Critically Ill Patients. N Engl J Med. 2013 Apr 18;368(16):1489-1497. [abstract] (File Cabinet, EB Journal Club)
  • Boonen E, Vervenne H, Meersseman P, Andrew R, Mortier L, Declercq PE, Vanwijngaerden YM, Spriet I, Wouters PJ, Vander Perre S, Langouche L, Vanhorebeek I, Walker BR, Van den Berghe G. Reduced Cortisol Metabolism during Critical Illness. N Engl J Med. 2013 Apr 18;368(16):1477-1488. [abstract] (File Cabinet)
  • Edwards JD, Houtrow AJ, Vasilevskis EE, Dudley RA, Okumura MJ. Multi-institutional Profile of Adults Admitted to Pediatric Intensive Care Units. JAMA Pediatr. 2013 Mar 18:1-8. [abstract] (File Cabinet, EB Journal Club)
  • Chowdhury MM, McKenzie SA, Pearson CC, Carr S, Pao C, Shah AR, Reus E, Eliahoo J, Gordon F, Bland H, Habibi P. Heliox Therapy in Bronchiolitis: Phase III Multicenter Double-Blind Randomized Controlled Trial. Pediatrics. 2013; 31:661–669. [abstract] (File Cabinet, EB Journal Club)

March 2013

  • Gattas DJ, Dan A, Myburgh J, Billot L, Lo S, Finfer S; CHEST Management Committee. Fluid resuscitation with 6 % hydroxyethyl starch (130/0.4 and 130/0.42) in acutely ill patients: systematic review of effects on mortality and treatment with renal replacement therapy. Intensive Care Med. 2013 Apr;39(4):558-68. [abstract] (File Cabinet, EB Journal Club)
  • Boonen E, Vervenne H, Meersseman P, Andrew R, Mortier L, Declercq PE, Vanwijngaerden YM, Spriet I, Wouters PJ, Vander Perre S, Langouche L, Vanhorebeek I, Walker BR, Van den Berghe G. Reduced Cortisol Metabolism during Critical Illness. N Engl J Med. 2013 DOI: 10.1056/NEJMoa1214969 [abstract] (File Cabinet)
  • Zarychanski R, Abou-Setta AM, Turgeon AF, Houston BL, McIntyre L, Marshall JC, Fergusson DA. Association of hydroxyethyl starch administration with mortality and acute kidney injury in critically ill patients requiring volume resuscitation: a systematic review and meta-analysis. JAMA. 2013 Feb 20;309(7):678-88. [abstract] (File Cabinet, EB Journal Club)
  • Fracchia MS, El Saleeby CM, Murali MR, Sagar P, Mino-Kenudson M. Case records of the Massachusetts General Hospital. Case 9-2013. A 9-year-old boy with fever, cough, respiratory distress, and chest pain. N Engl J Med. 2013 Mar 21;368(12):1141-50 [citation] (Case Reports)
  • Opal SM, Laterre PF, Francois B, LaRosa SP, Angus DC, Mira JP, Wittebole X, Dugernier T, Perrotin D, Tidswell M, Jauregui L, Krell K, Pachl J, Takahashi T, Peckelsen C, Cordasco E, Chang CS, Oeyen S, Aikawa N, Maruyama T, Schein R, Kalil AC, Van Nuffelen M, Lynn M, Rossignol DP, Gogate J, Roberts MB, Wheeler JL, Vincent JL; ACCESS Study Group. Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: the ACCESS randomized trial. JAMA. 2013 Mar 20;309(11):1154-62. [abstract] (EB Journal Club, File Cabinet)
  • Duncan CN, Lehmann LE, Cheifetz IM, Greathouse K, Haight AE, Hall MW, Herschberger A, Hill KS, Moffet JR, Morrison RR, Norris AL, Petrovic A, Spear DA, Steiner ME, Talano JA, Tamburro RF, Wagner J, McArthur J; for the Pediatric Acute Lung Injury and Sepsis (PALISI) Network. Clinical Outcomes of Children Receiving Intensive Cardiopulmonary Support During Hematopoietic Stem Cell Transplant* Pediatr Crit Care Med. 2013 Mar;14(3):261-267. [abstract] (File Cabinet, EB Journal Club)
  • Kneyber MC, Grotenhuis F, Berger RF, Ebels TW, Burgerhof JG, Albers MJ. Transfusion of Leukocyte-Depleted RBCs Is Independently Associated With Increased Morbidity After Pediatric Cardiac Surgery. Pediatr Crit Care Med. 2013;14:298–305. [abstract; full-text (pdf; 600K)] (File Cabinet, EB Journal Club)
  • Askenazi DJ, Goldstein SL, Koralkar R, Fortenberry J, Baum M, Hackbarth R, Blowey D, Bunchman TE, Brophy PD, Symons J, Chua A, Flores F, Somers MJ. Continuous Renal Replacement Therapy for Children ≤10 kg: A Report from the Prospective Pediatric Continuous Renal Replacement Therapy Registry. J Pediatr. 2013 Mar;162(3):587-592 [abstract] (EB Journal Club)
  • Sanders RC Jr, Giuliano JS Jr, Sullivan JE, Brown CA 3rd, Walls RM, Nadkarni V, Nishisaki A; for the National Emergency Airway Registry for Children Investigators and Pediatric Acute Lung Injury and Sepsis Investigators Network. Level of Trainee and Tracheal Intubation Outcomes. Pediatrics. 2013; 131;e821. [abstract] (EB Journal Club)
  • Clark JD, Dudzinski DM. The Culture of Dysthanasia: Attempting CPR in Terminally Ill Children. Pediatrics. 2013; 131;572-580. [abstract]
  • Leal-Noval SR, Muñoz-GĂłmez M, JimĂ©nez-Sánchez M, Cayuela A, Leal-Romero M, Puppo-Moreno A, Enamorado J, Arellano-Orden V. Red blood cell transfusion in non-bleeding critically ill patients with moderate anemia: is there a benefit? Intensive Care Med. 2013 Mar;39(3):445-53. [abstract] (EB Journal Club)
  • Alhazzani W, Alenezi F, Jaeschke RZ, Moayyedi P, Cook DJ. Proton pump inhibitors versus histamine 2 receptor antagonists for stress ulcer prophylaxis in critically ill patients: a systematic review and meta-analysis*. Crit Care Med. 2013 Mar;41(3):693-705. [abstract] (EB Journal Club)
  • Guntupalli K, Dean N, Morris PE, Bandi V, Margolis B, Rivers E, Levy M, Lodato RF, Ismail PM, Reese A, Schaumberg JP, Malik R, Dellinger RP; for the TLF LF-0801 Investigator Group. A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Efficacy of Talactoferrin in Patients With Severe Sepsis* Crit Care Med. 2013 Mar;41(3):706-716. [abstract] (EB Journal Club)

February 2013

  • McPhee LC, Badawi O, Fraser GL, Lerwick PA, Riker RR, Zuckerman IH, Franey C, Seder DB. Single-Dose Etomidate Is Not Associated With Increased Mortality in ICU Patients With Sepsis: Analysis of a Large Electronic ICU Database. Crit Care Med. 2013; 41:774-783 [abstract] (File Cabinet, EB Journal Club)
  • Alhazzani W, Alenezi F, Jaeschke RZ, Moayyedi P, Cook DJ. Proton Pump Inhibitors Versus Histamine 2 Receptor Antagonists for Stress Ulcer Prophylaxis in Critically Ill Patients: A Systematic Review and Meta-Analysis. Care Med 2013; 41:693–705 [abstract] (File Cabinet, EB Journal Club)
  • Nishisaki A, Turner DA, Brown CA 3rd, Walls RM, Nadkarni VM; for the National Emergency Airway Registry for Children (NEAR4KIDS) and Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. A National Emergency Airway Registry for Children: Landscape of Tracheal Intubation in 15 PICUs. Crit Care Med 2013; 41:874-885 [abstract] (File Cabinet)
  • Hymel KP, Willson DF, Boos SC, Pullin DA, Homa K, Lorenz DJ, Herman BE, Graf JM, Isaac R, Armijo-Garcia V, Narang SK; Pediatric Brain Injury Research Network (PediBIRN) Investigators. Derivation of a Clinical Prediction Rule for Pediatric Abusive Head Trauma* Pediatr Crit Care Med. 2013 Feb;14(2):210-220. [abstract] (File Cabinet, EB Journal Club)
  • Cholette JM, Powers KS, Alfieris GM, Angona R, Henrichs KF, Masel D, Swartz MF, Daugherty LE, Belmont K, Blumberg N. Transfusion of Cell Saver Salvaged Blood in Neonates and Infants Undergoing Open Heart Surgery Significantly Reduces RBC and Coagulant Product Transfusions and Donor Exposures: Results of a Prospective, Randomized, Clinical Trial*. Pediatr Crit Care Med. 2013 Feb;14(2):137-47. [abstract; full-text (pdf; 600K)] (File Cabinet, EB Journal Club)
  • Barst RJ, Ivy DD, Gaitan G, Szatmari A, Rudzinski A, Garcia AE, Sastry BK, Pulido T, Layton GR, Serdarevic-Pehar M, Wessel DL. A randomized, double-blind, placebo-controlled, dose-ranging study of oral sildenafil citrate in treatment-naive children with pulmonary arterial hypertension. Circulation. 2012 Jan 17;125(2):324-34. [abstract] (File Cabinet, EB Journal Club)
  • LĂłpez-Herce J, Del Castillo J, Matamoros M, Cañadas S, Rodriguez-Calvo A, Cecchetti C, Rodriguez-Núñez A, Alvarez AC; Iberoamerican Pediatric Cardiac Arrest Study Network RIBEPCI. Factors associated with mortality in pediatric in-hospital cardiac arrest: a prospective multicenter multinational observational study. Intensive Care Med. 2013 Feb;39(2):309-18. [abstract] (File Cabinet, EB Journal Club)
  • Pappalardo F, Pieri M, Greco T, Patroniti N, Pesenti A, Arcadipane A, Ranieri VM, Gattinoni L, Landoni G, Holzgraefe B, Beutel G, Zangrillo A; Italian ECMOnet. Predicting mortality risk in patients undergoing venovenous ECMO for ARDS due to influenza A (H1N1) pneumonia: the ECMOnet score. Intensive Care Med. 2013 Feb;39(2):275-81. [abstract] (File Cabinet, EB Journal Club)
  • Lee JH, Rehder KJ, Williford L, Cheifetz IM, Turner DA. Use of high flow nasal cannula in critically ill infants, children, and adults: a critical review of the literature. Intensive Care Med. 2013 Feb;39(2):247-57 [abstract] (File Cabinet)
  • The presentations at the Pediatric Section Business meeting from the 42nd SCCM Congress in San Juan, Puerto Rico, January 21, 2013, are here... (pdf; 1.2 MB) (Organizations/Meetings)
  • Karamlou T, Vafaeezadeh M, Parrish AM, Cohen GA, Welke KF, Permut L, McMullan DM. Increased extracorporeal membrane oxygenation center case volume is associated with improved extracorporeal membrane oxygenation survival among pediatric patients. J Thorac Cardiovasc Surg. 2013 Feb;145(2):470-5. [abstract] (File Cabinet, EB Journal Club)
  • Batt J, Dos Santos CC, Cameron JI, Herridge MS. Intensive-Care Unit Acquired Weakness (ICUAW): Clinical Phenotypes and Molecular Mechanisms. Am J Respir Crit Care Med 2013; 187:238-246. [abstract] (File Cabinet)
  • Pham T, Combes A, RozĂ© H, Chevret S, Mercat A, Roch A, Mourvillier B, Ara-Somohano C, Bastien O, Zogheib E, Clavel M, Constan A, Richard JC, Brun-Buisson C, Brochard L; For the REVA Research Network. Extracorporeal Membrane Oxygenation for Pandemic Influenza A(H1N1) Induced Acute Respiratory Distress Syndrome. A Cohort Study and Propensity-matched Analysis. Am J Respir Crit Care Med 2013; 187:276–285. [abstract] (File Cabinet, EB Journal Club)
  • Ferguson ND, Scales DC, Pinto R, Wilcox ME, Cook DJ, Guyatt GH, SchĂĽnemann HJ, Marshall JC, Herridge MS, Meade MO; for the Canadian Critical Care Trials Group. Integrating Mortality and Morbidity Outcomes: Using Quality-Adjusted Life Years in Critical Care Trials. Am J Respir Crit Care Med 2013; 187:256–261 [abstract] (File Cabinet)
  • Chen LM, Kennedy EH, Sales A, Hofer TP. Use of Health IT for Higher-Value Critical Care. N Engl J Med. 2013 Jan 30. [Epub ahead of print] [abstract] (File Cabinet)
  • Rowan CM, Hege KM, Speicher RH, Goodman M, Perkins SM, Slaven JE, Westenkirchner DF, Haut PR, Nitu ME. Oxygenation index predicts mortality in pediatric stem cell transplant recipients requiring mechanical ventilation. Pediatr Transplant. 2012 Sep;16(6):645-50. [abstract] (File Cabinet, EB Journal Club)
  • van Nood E, Vrieze A, Nieuwdorp M, Fuentes S, Zoetendal EG, de Vos WM, Visser CE, Kuijper EJ, Bartelsman JF, Tijssen JG, Speelman P, Dijkgraaf MG, Keller JJ. Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile. N Engl J Med. 2013; 368:407-415 [abstract] (File Cabinet)
  • Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb SA, Beale RJ, Vincent JL, Moreno R; and the Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup. Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012. Crit Care Med. 2013 Feb;41(2):580-637. [abstract] (File Cabinet)
  • Al-Qahtani S, Al-Dorzi HM, Tamim HM, Hussain S, Fong L, Taher S, Al-Knawy BA, Arabi Y. Impact of an Intensivist-Led Multidisciplinary Extended Rapid Response Team on Hospital-Wide Cardiopulmonary Arrests and Mortality. Crit Care Med. 2013; 41:506–517 [abstract] (File Cabinet, EB Journal Club)

December 2012

  • Curley MA, Meyer EC, Scoppettuolo LA, McGann EA, Trainor BP, Rachwal C, Hickey PA. Parent Presence during Invasive Procedures and Resuscitation: Evaluating a Clinical Practice Change. Am J Respir Crit Care Med. 2012; 186:1133-1139. [abstract] (File Cabinet)
  • Nayak PP, Davies P, Narendran P, Laker S, Gao F, Gough SC, Stickley J, Morris KP. Early change in blood glucose concentration is an indicator of mortality in critically ill children. Intensive Care Med. 2013 Jan;39(1):123-8. [abstract] (File Cabinet, EB Journal Club)
  • SigurtĂ  A, Zanaboni C, Canavesi K, Citerio G, Beretta L, Stocchetti N. Intensive care for pediatric traumatic brain injury. Intensive Care Med. 2013 Jan;39(1):129-36. [abstract] (File Cabinet, EB Journal Club)
  • The December 2012 WFPICCS newsletter is here... (Organizations)
  • Mekontso Dessap A, Roche-Campo F, Kouatchet A, Tomicic V, Beduneau G, Sonneville R, Cabello B, Jaber S, Azoulay E, Castanares-Zapatero D, Devaquet J, Lellouche F, Katsahian S, Brochard L. Natriuretic Peptide-driven Fluid Management during Ventilator Weaning: A Randomized Controlled Trial. Am J Respir Crit Care Med. 2012 Dec 15;186(12):1256-63 [abstract] (File Cabinet, EB Journal Club)
  • Timsit JF, Mimoz O, Mourvillier B, Souweine B, Garrouste-Orgeas M, Alfandari S, Plantefeve G, Bronchard R, Troche G, Gauzit R, Antona M, Canet E, Bohe J, Lepape A, Vesin A, Arrault X, Schwebel C, Adrie C, Zahar JR, Ruckly S, Tournegros C, Lucet JC. Randomized Controlled Trial of Chlorhexidine Dressing and Highly Adhesive Dressing for Preventing Catheter-related Infections in Critically Ill Adults. Am J Respir Crit Care Med. 2012 Dec 15;186(12):1272-8. [abstract] (File Cabinet, EB Journal Club)
  • The AAP Section on Critical Care (SOCC) is pleased to announce availability of two small grants for young investigators for projects devoted to education in Pediatric Critical Care Medicine and outcomes of quality and safety initiatives in the PICU. Read more... (Organizations)
  • Chesnut RM, Temkin N, Carney N, Dikmen S, Rondina C, Videtta W, Petroni G, Lujan S, Pridgeon J, Barber J, Machamer J, Chaddock K, Celix JM, Cherner M, Hendrix T. A trial of intracranial-pressure monitoring in traumatic brain injury. N Engl J Med. 2012 Dec 27;367(26):2471-81. [abstract](File Cabinet, EB Journal Club)

November 2012

  • Serpa Neto A, Cardoso SO, Manetta JA, Pereira VG, EspĂłsito DC, Pasqualucci Mde O, Damasceno MC, Schultz MJ. Association between use of lung-protective ventilation with lower tidal volumes and clinical outcomes among patients without acute respiratory distress syndrome: a meta-analysis. JAMA. 2012 Oct 24;308(16):1651-9. [abstract] (File Cabinet, EB Journal Club)
  • Mesotten D, Gielen M, Sterken C, Claessens K, Hermans G, Vlasselaers D, Lemiere J, Lagae L, Gewillig M, Eyskens B, Vanhorebeek I, Wouters PJ, Van den Berghe G. Neurocognitive development of children 4 years after critical illness and treatment with tight glucose control: a randomized controlled trial. JAMA. 2012 Oct 24;308(16):1641-50 [abstract] (File Cabinet)
  • Thomas NJ, Guardia CG, Moya FR, Cheifetz IM, Markovitz B, Cruces P, Barton P, Segal R, Simmons P, Randolph AG, for the PALISI Network. A pilot, randomized, controlled clinical trial of lucinactant, a peptide-containing synthetic surfactant, in infants with acute hypoxemic respiratory failure. Pediatr Crit Care Med. 13(6):646-653 [abstract] (File Cabinet, EB Journal Club)
  • Chima RS, Daniels RC, Kim MO, Li D, Wheeler DS, Davies SM, Jodele S. Improved outcomes for stem cell transplant recipients requiring pediatric intensive care. Pediatr Crit Care Med. 2012 Nov;13(6):e336-42 [abstract; full-text (pdf 376K)] (File Cabinet, EB Journal Club)
  • Alten JA, Borasino S, Gurley WQ, Law MA, Toms R, Dabal RJ. Ultrasound-guided femoral vein catheterization in neonates with cardiac disease*. Pediatr Crit Care Med. 2012 Nov;13(6):654-9. [abstract] (File Cabinet, EB Journal Club)
  • Casserly B, Gerlach H, Phillips GS, Lemeshow S, Marshall JC, Osborn TM, Levy MM. Low-dose steroids in adult septic shock: results of the Surviving Sepsis Campaign. Intensive Care Med. 2012 Dec;38(12):1946-54. [abstract] (File Cabinet, EB Journal Club)
  • Morris KP, McShane P, Stickley J, Parslow RC. The relationship between blood lactate concentration, the Paediatric Index of Mortality 2 (PIM2) and mortality in paediatric intensive care. Intensive Care Med. 2012 Dec;38(12):2042-6. [abstract] (File Cabinet, EB Journal Club)
  • Rippel C, South M, Butt WW, Shekerdemian LS. Vitamin D status in critically ill children. Intensive Care Med. 2012 Dec;38(12):2055-62. [abstract] (File Cabinet, EB Journal Club)
  • Verweij EJ, Hogenbirk K, Roest AA, van Brempt R, Hazekamp MG, de Jonge E. Serum cortisol concentration with exploratory cut-off values do not predict the effects of hydrocortisone administration in children with low cardiac output after cardiac surgery. Interact Cardiovasc Thorac Surg. 2012 Oct;15(4):685-9. [abstract] (File Cabinet, EB Journal Club)
  • Janz DR, Hollenbeck RD, Pollock JS, McPherson JA, Rice TW. Hyperoxia is associated with increased mortality in patients treated with mild therapeutic hypothermia after sudden cardiac arrest*. Crit Care Med. 2012 Dec;40(12):3135-9. [abstract] (File Cabinet, EB Journal Club)
  • Park DW, Chun BC, Kwon SS, Yoon YK, Choi WS, Sohn JW, Peck KR, Kim YS, Choi YH, Choi JY, Kim SI, Eom JS, Kim HY, Cheong HJ, Song YG, Choi HJ, Kim JM, Kim MJ. Red blood cell transfusions are associated with lower mortality in patients with severe sepsis and septic shock: A propensity-matched analysis* Crit Care Med. 2012 Dec;40(12):3140-3145. [abstract] (File Cabinet, EB Journal Club)
  • LĂłpez-Fernández Y, Azagra AM, de la Oliva P, Modesto V, Sánchez JI, Parrilla J, Arroyo MJ, Reyes SB, Pons-Ă“dena M, LĂłpez-Herce J, Fernández RL, Kacmarek RM, Villar J. Pediatric Acute Lung Injury Epidemiology and Natural History Study: Incidence and outcome of the acute respiratory distress syndrome in children* Crit Care Med. 2012 Dec;40(12):3238-3245. [abstract] (File Cabinet, EB Journal Club) abstract] (File Cabinet, EB Journal Club)

October 2012

  • Virtual Mentor: American Medical Association Journal of Ethics. October 2012, Volume 14, Number 10: 755-820. Pediatric Critical Care and Emergency Medicine [pdf] (File Cabinet)
  • Myburgh JA, Finfer S, Bellomo R, Billot L, Cass A, Gattas D, Glass P, Lipman J, Liu B, McArthur C, McGuinness S, Rajbhandari D, Taylor CB, Webb SA; the CHEST Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Hydroxyethyl Starch or Saline for Fluid Resuscitation in Intensive Care. N Engl J Med. 2012. DOI: 10.1056/NEJMoa1209759 [abstract] (File Cabinet, EB Journal Club)
  • Nayak PP, Sheth J, Cox PN, Davidson L, Forte V, Manlhiot C, McCrindle BW, Schwartz SM, Solomon M, Van Arsdell GS, Sivarajan VB. Predictive value of bronchoscopy after infant cardiac surgery: a prospective study. Intensive Care Med. 2012 Nov;38(11):1851-7. [abstract] (File Cabinet, EB Journal Club)
  • Knudson JD, Neish SR, Cabrera AG, Lowry AW, Shamszad P, Morales DL, Graves DE, Williams EA, Rossano JW. Prevalence and outcomes of pediatric in-hospital cardiopulmonary resuscitation in the United States: An analysis of the Kids' Inpatient Database*. Crit Care Med. 2012 Nov;40(11):2940-4. [abstract] (File Cabinet, EB Journal Club)
  • Chan CM, Mitchell AL, Shorr AF. Etomidate is associated with mortality and adrenal insufficiency in sepsis: A meta-analysis*. Crit Care Med. 2012 Nov;40(11):2945-53 [abstract] (File Cabinet, EB Journal Club)

September 2012

  • World Federation of Pediatric Intensive & Critical Care Societies (WFPICCS) September, 2012 newsletter (5:3) is here...
  • Agus MSD, Steil GM, Wypij D, Costello JM, Laussen PC, Langer M, Alexander JL, Scoppettuolo LA, Pigula FA, Charpie JR, Ohye RG, Gaies MG, for the SPECS Study Investigators. Tight Glycemic Control versus Standard Care after Pediatric Cardiac Surgery. N Engl J Med 2012. 367:1208-19 (early release 9/7/2012) [abstract] (File Cabinet, EB Journal Club)
  • Bhalala US, Nishisaki A, McQueen D, Bird GL, Morrison WE, Nadkarni VM, Nathan M, Starr JP. Change in regional (somatic) near-infrared spectroscopy is not a useful indictor of clinically detectable low cardiac output in children after surgery for congenital heart defects. Pediatr Crit Care Med. 2012; 13:529–534 [abstract; full-text (pdf: 203K)] (File Cabinet, EB Journal Club)
  • Jaramillo-Bustamante JC, MarĂ­n-Agudelo A, Fernández-Laverde M, Bareño-Silva J. Epidemiology of sepsis in pediatric intensive care units: First Colombian Multicenter Study. Pediatr Crit Care Med. 2012; 13:501–508 [abstract] (File Cabinet, EB Journal Club)
  • Valentine SL, Sapru A, Higgerson RA, Spinella PC, Flori HR, Graham DA, Brett M, Convery M, Christie LM, Karamessinis L, Randolph AG. Fluid balance in critically ill children with acute lung injury. Crit Care Med. 2012; 40:2883–2889 [abstract] (File Cabinet, EB Journal Club)
  • NICE-SUGAR Study Investigators, Finfer S, Liu B, Chittock DR, Norton R, Myburgh JA, McArthur C, Mitchell I, Foster D, Dhingra V, Henderson WR, Ronco JJ, Bellomo R, Cook D, McDonald E, Dodek P, HĂ©bert PC, Heyland DK, Robinson BG. Hypoglycemia and risk of death in critically ill patients. N Engl J Med. 2012 Sep 20;367(12):1108-18. [abstract] (File Cabinet, EB Journal Club)
  • Ferguson ND, Fan E, Camporota L, Antonelli M, Anzueto A, Beale R, Brochard L, Brower R, Esteban A, Gattinoni L, Rhodes A, Slutsky AS, Vincent JL, Rubenfeld GD, Thompson BT, Ranieri VM. The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material. Intensive Care Med. 2012 Oct;38(10):1573-82. [abstract] (File Cabinet)
  • Asehnoune K, Mahe PJ, Seguin P, Jaber S, Jung B, Guitton C, Chatel-Josse N, Subileau A, Tellier AC, Masson F, Renard B, Malledant Y, Lejus C, Volteau C, SĂ©bille V, Roquilly A. Etomidate increases susceptibility to pneumonia in trauma patients. Intensive Care Med. 2012 Oct;38(10):1673-82. [abstract] (File Cabinet, EB Journal Club)
  • Tabbutt S, Ghanayem N, Ravishankar C, Sleeper LA, Cooper DS, Frank DU, Lu M, Pizarro C, Frommelt P, Goldberg CS, Graham EM, Krawczeski CD, Lai WW, Lewis A, Kirsh JA, Mahony L, Ohye RG, Simsic J, Lodge AJ, Spurrier E, Stylianou M, Laussen P; Pediatric Heart Network Investigators. Risk factors for hospital morbidity and mortality after the Norwood procedure: A report from the Pediatric Heart Network Single Ventricle Reconstruction trial. J Thorac Cardiovasc Surg. 2012 Oct;144(4):882-95. [abstract] (File Cabinet, EB Journal Club)
  • Shein SL, Bell MJ, Kochanek PM, Tyler-Kabara EC, Wisniewski SR, Feldman K, Makoroff K, Scribano PV, Berger RP. Risk factors for mortality in children with abusive head trauma. J Pediatr. 2012 Oct;161(4):716-722. [abstract] (File Cabinet, EB Journal Club)

August 2012

  • Marik PE, Flemmer M, Harrison W. The risk of catheter-related bloodstream infection with femoral venous catheters as compared to subclavian and internal jugular venous catheters: A systematic review of the literature and meta-analysis*. Crit Care Med. 2012 Aug;40(8):2479-85. [abstract] (File Cabinet, EB Journal Club)
  • Newth CJ, Meert KL, Clark AE, Moler FW, Zuppa AF, Berg RA, Pollack MM, Sward KA, Berger JT, Wessel DL, Harrison RE, Reardon J, Carcillo JA, Shanley TP, Holubkov R, Dean JM, Doctor A, Nicholson CE; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network. Fatal and Near-Fatal Asthma in Children: The Critical Care Perspective. J Pediatr 2012;161:214-21. [abstract] (File Cabinet, EB Journal Club)
  • Bechard LJ, Parrott JS, Mehta NM. Systematic Review of Energy and Protein Intake on Protein Balance in Critically Ill Children. J Pediatr 2012;161:333-9 [abstract] (File Cabinet)
  • Paul R, Neuman MI, Monuteaux MC, Melendez E. Adherence to PALS Sepsis Guidelines and Hospital Length of Stay. Pediatrics. 2012;130 e273-e280 [abstract] (File Cabinet)
  • Selewski DT, Cornell TT, Blatt NB, Han YY, Mottes T, Kommareddi M, Gaies MG, Annich GM, Kershaw DB, Shanley TP, Heung M. Fluid overload and fluid removal in pediatric patients on extracorporeal membrane oxygenation requiring continuous renal replacement therapy. Crit Care Med. 2012; 40:2694–2699. [abstract] (File Cabinet, EB Journal Club)
  • Ropper AH. Hyperosmolar Therapy for Raised Intracranial Pressure. N Engl J Med 2012; 367:746-752 [citation] (File Cabinet)

July 2012

  • Mehta NM, Bechard LJ, Cahill N, Wang M, Day A, Duggan CP, Heyland DK. Nutritional practices and their relationship to clinical outcomes in critically ill children-An international multicenter cohort study*. Crit Care Med. 2012 Jul;40(7):2204-11. [abstract] (File Cabinet, EB Journal Club)
  • Journal of Pediatric Intensive Care (Journals)
  • Blot SI, Taccone FS, Van den Abeele AM, Bulpa P, Meersseman W, Brusselaers N, Dimopoulos G, Paiva JA, Misset B, Rello J, Vandewoude K, Vogelaers D; the AspICU Study Investigators. A Clinical Algorithm to Diagnose Invasive Pulmonary Aspergillosis in Critically Ill Patients. Am J Respir Crit Care Med. 2012; 186:56-64. [abstract] (File Cabinet, EB Journal Club)
  • Gibot S, BĂ©nĂ© MC, Noel R, Massin F, Guy J, Cravoisy A, Barraud D, De Carvalho Bittencourt M, Quenot JP, Bollaert PE, Faure G, Charles PE. Combination Biomarkers to Diagnose Sepsis in the Critically Ill Patient. Am J Respir Crit Care Med. 2012; 186:65-71. [abstract] (File Cabinet, EB Journal Club)
  • Leeuwenburgh-Pronk WG, Smith PJ, van Vught AJ, Lantos JD, Tibboel D, de Hoog M, Buysse C. A Baby With Meningococcemia and Septic Shock. Pediatrics. 2012;130 134-138. [citation] (Case Reports)
  • Perner A, Haase N, Guttormsen AB, Tenhunen J, Klemenzson G, Aneman A, Madsen KR, Møller MH, Elkjær JM, Poulsen LM, Bendtsen A, Winding R, Steensen M, Berezowicz P, Søe-Jensen P, Bestle M, Strand K, Wiis J, White JO, Thornberg KJ, Quist L, Nielsen J, Andersen LH, Holst LB, Thormar K, Kjældgaard AL, Fabritius ML, Mondrup F, Pott FC, Møller TP, Winkel P, Wetterslev J; the 6S Trial Group and the Scandinavian Critical Care Trials Group. Hydroxyethyl Starch 130/0.4 versus Ringer's Acetate in Severe Sepsis. N Engl J Med. 2012 10.1056/NEJMoa1204242 [abstract] (File Cabinet, EB Journal Club)
  • Eyssallenne AP. How Far Do You Go? Intensive Care in a Resource-Poor Setting. N Engl J Med 2012; 367:8-9 [full-text] (International Child Health)
  • Brogan TV, Zabrocki L, Thiagarajan RR, Rycus PT, Bratton SL. Prolonged extracorporeal membrane oxygenation for children with respiratory failure. Pediatr Crit Care Med. 2012; 13:e249–e254 [abstract; full-text (pdf 2.1 MB)] (File Cabinet, EB Journal Club)
  • Reiter PD, Wathen B, Valuck RJ, Dobyns EL. Thrombosis risk factor assessment and implications for prevention in critically ill children. Pediatr Crit Care Med. 2012; 13:381–386. [abstract] (File Cabinet, EB Journal Club)
  • Bratton SL, Newth CJ, Zuppa AF, Moler FW, Meert KL, Berg RA, Berger J, Wessel D, Pollack M, Harrison R, Carcillo JA, Shanley TP, Liu T, Holubkov R, Michael Dean J, Nicholson CE; for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network. Critical care for pediatric asthma: Wide care variability and challenges for study. Pediatr Crit Care Med. 2011; 13:407–414. [abstract] (File Cabinet)
  • Shore PM, Huang R, Roy L, Darnell C, Grein H, Robertson T, Thompson L. Development of a bedside tool to predict time to death after withdrawal of life-sustaining therapies in infants and children. Pediatr Crit Care Med. 2012; 13:415–422. [abstract] (File Cabinet, EB Journal Club)
  • Bennett TD, Riva-Cambrin J, Keenan HT, Korgenski EK, Bratton SL. Variation in Intracranial Pressure Monitoring and Outcomes in Pediatric Traumatic Brain InjuryTBI Intracranial Pressure Monitoring and Outcomes. Arch Pediatr Adolesc Med. 2012 Jul 1;166(7):641-7. [abstract] (File Cabinet, EB Journal Club)
  • Leteurtre S, Grandbastien B, Leclerc F, Parslow R; Groupe Francophone de RĂ©animation et Urgences PĂ©diatriques; Paediatric Intensive Care Audit Network. International comparison of the performance of the paediatric index of mortality (PIM) 2 score in two national data sets. Intensive Care Med. 2012 Aug;38(8):1372-80. [abstract] (File Cabinet)
  • Tibby SM, Durward A, Goh CT, Thorburn K, Morris K, Broadhead M, Peters MJ. Clinical course and outcome for critically ill children with Down syndrome: a retrospective cohort study. Intensive Care Med. 2012 Aug;38(8):1365-71. [abstract] (File Cabinet, EB Journal Club)
  • Hörburger D, Testori C, Sterz F, Herkner H, Krizanac D, Uray T, Schober A, Stöckl M, Stratil P, Weiser C, WallmĂĽller C, Holzer M. Mild therapeutic hypothermia improves outcomes compared with normothermia in cardiac-arrest patients-a retrospective chart review*. Crit Care Med. 2012 Aug;40(8):2315-9. [abstract] (File Cabinet, EB Journal Club)

June 2012

  • The RENAL Replacement Therapy Study Investigators. An observational study fluid balance and patient outcomes in the randomized evaluation of normal vs. augmented level of replacement therapy trial* Crit Care Med. 2012 Jun;40(6):1753-1760. [abstract] (File Cabinet, EB Journal Club)
  • Szpilman D, Bierens JJ, Handley AJ, Orlowski JP. Drowning. N Engl J Med. 2012 May 31;366(22):2102-10. [citation] (File Cabinet)
  • The Patient-Centered Outcomes Research Institute (PCORI) announces its first cycle of Funding Opportunities (Clinical Research)
  • Algra SO, Driessen MM, Schadenberg AW, Schouten AN, Haas F, Bollen CW, Houben ML, Jansen NJ. Bedside prediction rule for infections after pediatric cardiac surgery. Intensive Care Med. 2012 Mar;38(3):474-81. [abstract] (File Cabinet, EB Journal Club)
  • Brunkhorst FM, Oppert M, Marx G, Bloos F, Ludewig K, Putensen C, Nierhaus A, Jaschinski U, Meier-Hellmann A, Weyland A, GrĂĽndling M, Moerer O, Riessen R, Seibel A, Ragaller M, BĂĽchler MW, John S, Bach F, Spies C, Reill L, Fritz H, Kiehntopf M, Kuhnt E, Bogatsch H, Engel C, Loeffler M, Kollef MH, Reinhart K, Welte T, German Study Group Competence Network Sepsis Sepnet FT. Effect of Empirical Treatment With Moxifloxacin and Meropenem vs Meropenem on Sepsis-Related Organ Dysfunction in Patients With Severe Sepsis: A Randomized TrialTreatment for Sepsis-Related Organ Dysfunction. JAMA. 2012 Jun 13;307(22):2390-9. [abstract] (File Cabinet, EB Journal Club)
  • Edwards JD, Houtrow AJ, Vasilevskis EE, Rehm RS, Markovitz BP, Graham RJ, Dudley RA. Chronic conditions among children admitted to U.S. pediatric intensive care units: Their prevalence and impact on risk for mortality and prolonged length of stay* Crit Care Med. 2012 Jul;40(7):2196-2203. [abstract] (File Cabinet)
  • Agarwal HS, Saville BR, Slayton JM, Donahue BS, Daves S, Christian KG, Bichell DP, Harris ZL. Standardized postoperative handover process improves outcomes in the intensive care unit: A model for operational sustainability and improved team performance*. Crit Care Med. 2012 Jul;40(7):2109-15. [abstract] (File Cabinet)
  • Nishisaki A, Pines JM, Lin R, Helfaer MA, Berg RA, Tenhave T, Nadkarni VM. The impact of 24-hr, in-hospital pediatric critical care attending physician presence on process of care and patient outcomes*. Crit Care Med. 2012 Jul;40(7):2190-5. [abstract] (File Cabinet, EB Journal Club)
  • Agrawal S, Peters MJ, Adams GG, Pierce CM. Prevalence of retinal hemorrhages in critically ill children. Pediatrics. 2012 Jun;129(6):e1388-96. [abstract] (File Cabinet)
  • Kaufman J, Rannie M, Kahn MG, Vitaska M, Wathen B, Peyton C, Judd J, Quinby Z, da Cruz EM, Dobyns E. An interdisciplinary initiative to reduce unplanned extubations in pediatric critical care units. Pediatrics. 2012 Jun;129(6):e1594-600 [abstract] (File Cabinet)
  • Berwick DM. To Isaiah. JAMA. 2012;307(24):2597-2599. doi:10.1001/jama.2012.6911 [full-text]
  • Lamperti M, Bodenham AR, Pittiruti M, Blaivas M, Augoustides JG, Elbarbary M, Pirotte T, Karakitsos D, Ledonne J, Doniger S, Scoppettuolo G, Feller-Kopman D, Schummer W, Biffi R, Desruennes E, Melniker LA, Verghese ST. International evidence-based recommendations on ultrasound-guided vascular access. Intensive Care Med. 2012 Jul;38(7):1105-17 [abstract] (File Cabinet)
  • Ganu SS, Gautam A, Wilkins B, Egan J. Increase in use of non-invasive ventilation for infants with severe bronchiolitis is associated with decline in intubation rates over a decade. Intensive Care Med. 2012 Jul;38(7):1177-83. [abstract] (File Cabinet, EB Journal Club)
  • Davidson J, Tong S, Hancock H, Hauck A, da Cruz E, Kaufman J. Prospective validation of the vasoactive-inotropic score and correlation to short-term outcomes in neonates and infants after cardiothoracic surgery. Intensive Care Med. 2012 Jul;38(7):1184-90 [abstract] (File Cabinet, EB Journal Club)
  • Ricci Z, Garisto C, Favia I, Vitale V, Di Chiara L, Cogo PE. Levosimendan infusion in newborns after corrective surgery for congenital heart disease: randomized controlled trial. Intensive Care Med. 2012 Jul;38(7):1198-204 [abstract] (File Cabinet, EB Journal Club)
  • The Global Sepsis Alliance announces its first World Sepsis Day, September 13, 2012. It "aims to increase awareness and recognition of Sepsis and the need to diagnose and treat the illness early." (News)

May 2012

  • Macdonald PS, Aneman A, Bhonagiri D, Jones D, O'Callaghan G, Silvester W, Watson A, Dobb G. A systematic review and meta-analysis of clinical trials of thyroid hormone administration to brain dead potential organ donors*. Crit Care Med. 2012 May;40(5):1635-44. [abstract] (File Cabinet, EB Journal Club)
  • Walkey AJ, Wiener RS. Macrolide Antibiotics and Survival in Patients with Acute Lung Injury. Chest 2012; 141:1153-1159. [abstract] (File Cabinet, EB Journal Club)
  • picudoctor.org is a website/smartphone app resource for pediatric cardiac critical care. From Marc Anders, Royal Children's Hospital, Melbourne, Australia. (Software)
  • Arikan AA, Zappitelli M, Goldstein SL, Naipaul A, Jefferson LS, Loftis LL. Fluid overload is associated with impaired oxygenation and morbidity in critically ill children*. Pediatr Crit Care Med. 2012 May;13(3):253-8. [abstract; full-text (pdf; 408K)] (File Cabinet, EB Journal Club)
  • Nelson LP, Gold JI. Posttraumatic stress disorder in children and their parents following admission to the pediatric intensive care unit: A review. Pediatr Crit Care Med. 2012 May;13(3):338-47. [abstract] (File Cabinet)
  • Schortgen F, Clabault K, Katsahian S, Devaquet J, Mercat A, Deye N, Dellamonica J, Bouadma L, Cook F, Beji O, Brun-Buisson C, Lemaire F, Brochard L. Fever Control Using External Cooling in Septic Shock: a Randomized Controlled Trial. Am J Respir Crit Care Med. 2012; 185:1088-1095. [abstract] (File Cabinet, EB Journal Club)
  • The ARDS definition task force. Acute Respiratory Distress Syndrome: The Berlin Definition.JAMA. 2012;307(23):doi:10.1001/jama.2012.5669 [abstract] (File Cabinet)
  • Matthaiou DK, Ntani G, Kontogiorgi M, Poulakou G, Armaganidis A, Dimopoulos G. An ESICM systematic review and meta-analysis of procalcitonin-guided antibiotic therapy algorithms in adult critically ill patients. Intensive Care Med. 2012 Jun;38(6):940-9. [abstract] (File Cabinet, EB Journal Club)
  • Smalley N, Maclaren G, Best D, Paul E, Butt W. Outcomes in children with refractory pneumonia supported with extracorporeal membrane oxygenation. Intensive Care Med. 2012 Jun;38(6):1001-7.[abstract] (File Cabinet, EB Journal Club)
  • Jack T, Boehne M, Brent BE, Hoy L, Köditz H, Wessel A, Sasse M. In-line filtration reduces severe complications and length of stay on pediatric intensive care unit: a prospective, randomized, controlled trial. Intensive Care Med. 2012 Jun;38(6):1008-16. [abstract] (File Cabinet, EB Journal Club)
  • Silver G, Traube C, Kearney J, Kelly D, Yoon MJ, Nash Moyal W, Gangopadhyay M, Shao H, Ward MJ. Detecting pediatric delirium: development of a rapid observational assessment tool. Intensive Care Med. 2012 Jun;38(6):1025-31. [abstract] (File Cabinet, EB Journal Club)
  • Grollmuss O, Demontoux S, Capderou A, Serraf A, Belli E. Electrical velocimetry as a tool for measuring cardiac output in small infants after heart surgery. Intensive Care Med. 2012 Jun;38(6):1032-9.[abstract] (File Cabinet, EB Journal Club)
  • Ranieri VM, Thompson BT, Barie PS, Dhainaut JF, Douglas IS, Finfer S, GĂĄrdlund B, Marshall JC, Rhodes A, Artigas A, Payen D, Tenhunen J, Al-Khalidi HR, Thompson V, Janes J, Macias WL, Vangerow B, Williams MD; the PROWESS-SHOCK Study Group. Drotrecogin Alfa (Activated) in Adults with Septic Shock. N Engl J Med. 2012; 366:2055-2064. [abstract] (File Cabinet, EB Journal Club)
  • Wallace DJ, Angus DC, Barnato AE, Kramer AA, Kahn JM. Nighttime Intensivist Staffing and Mortality among Critically Ill Patients. N Engl J Med. 2012; 366:2093-101. [abstract] (File Cabinet, EB Journal Club)

April 2012

  • Videos In Clinical Medicine: Emergency Pericardiocentesis. Michael T. Fitch, M.D., Ph.D., Bret A. Nicks, M.D., Manoj Pariyadath, M.D., Henderson D. McGinnis, M.D., and David E. Manthey, M.D. N Engl J Med 2012; 366:e17March 22, 2012 [video link] (File Cabinet)
  • ESPNIC, the European Society for Paediatric and Neonatal Intensive Care announces the European Academy of Paediatric Societies Meeting (EAPS), October 5-9, 2012 (abstract closing April 15, 2012), in Istanbul, Turkey. A strong intensive care component is planned. (Organizations/Meetings)
  • Hagihara A, Hasegawa M, Abe T, Nagata T, Wakata Y, Miyazaki S. Prehospital epinephrine use and survival among patients with out-of-hospital cardiac arrest. JAMA. 2012 Mar 21;307(11):1161-8. [abstract] (File Cabinet, EB Journal Club)
  • Jakob SM, Ruokonen E, Grounds RM, Sarapohja T, Garratt C, Pocock SJ, Bratty JR, Takala J; Dexmedetomidine for Long-Term Sedation Investigators. Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials. JAMA. 2012 Mar 21;307(11):1151-60. [abstract] (File Cabinet, EB Journal Club)
  • Kor DJ, Kashyap R, Weiskopf RB, Wilson GA, van Buskirk CM, Winters JL, Malinchoc M, Hubmayr RD, Gajic O. Fresh Red Blood Cell Transfusion and Short-term Pulmonary, Immunologic, and Coagulation Status: a Randomized Clinical Trial. Am J Respir Crit Care Med. 2012; 185:842-850. [abstract] (File Cabinet, EB Journal Club)
  • Concato J. Is It Time for Medicine-Based Evidence? JAMA. 2012;307(15):1641-1643. [extract] (EBM Resources)
  • Srinivasan M, Turmelle M, Depalma LM, Mao J, Carlson DW. Procedural Sedation for Diagnostic Imaging in Children by Pediatric Hospitalists using Propofol: Analysis of the Nature, Frequency, and Predictors of Adverse Events and Interventions. J Pediatr. 2012; 160:801-6. [abstract] (File Cabinet, EB Journal Club)
  • Wong HR. Genetics and genomics in pediatric septic shock. Crit Care Med. 2012 May;40(5):1618-26. [abstract] (File Cabinet)

March 2012

  • We would like to invite you to join us at the 7th International Conference on Pediatric Continuous Renal Replacement Therapies (CRRT) and the 1st Symposium on Pediatric Acute Kidney Injury to be held in Cincinnati, OH Sept 27-30, 2012. This meeting will combine the ongoing educational and application of CRRT in the Intensive Care Unit with, this year, the addition of a novel focus on AKI. The AKI symposium will include sections on biomarkers, organ cross talk, ECMO, renal, hepatic and cardiac support systems all unitized in ICUs.

    This conference will be expanded to include neonatology, hepatology, cardiology, as well as intensive care and nephrology. Speakers and attendees will include nursing, pharmacists, technicians, industry and physicians. CME and CEUs will be available.

    Go to www.pcrrt.com for a link to the brochure and for registration for the meeting and for hotel accommodations.

    We encourage abstract submission with the submission deadline date of June 30, 2012. As in years past there will be 6 awarded travel grants for the best abstracts submitted by nursing or fellows. Instructions for abstract submission can be found at our web site www.pcrrt.com

  • Cline JM, Woods CR, Ervin SE, Rubin BK, Kirse DJ. Surveillance tracheal aspirate cultures do not reliably predict bacteria cultured at the time of an acute respiratory infection in children with tracheostomy tubes. Chest. 2012 Mar;141(3):625-31. [abstract] (File Cabinet)
  • Alrajhi K, Woo MY, Vaillancourt C. Test Characteristics of Ultrasonography for the Detection of Pneumothorax: A Systematic Review and Meta-analysis. Chest. 2012 Mar;141(3):703-8 [abstract] (File Cabinet, EB Journal Club)
  • Streiner DL, Norman GR. Mine is bigger than yours: measures of effect size in research. Chest. 2012 Mar;141(3):595-8. [abstract] (EB Resources)
  • Ingaramo OA, Khemani RG, Markovitz BP, Epstein D. Effect of race on the timing of the Glenn and Fontan procedures for single-ventricle congenital heart disease. Pediatr Crit Care Med. 2012; 13:174 –177 [abstract] (File Cabinet, EB Journal Club)
  • Carcillo JA, Dean JM, Holubkov R, Berger J, Meert KL, Anand KJ, Zimmerman J, Newth CJ, Harrison R, Burr J, Willson CC, Nicholson C and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Collaborative Pediatric Critical Care Research Network (CPCCRN). The randomized comparative pediatric critical illness stress-induced immune suppression (CRISIS) prevention trial. Pediatr Crit Care Med 2012; 13:165–173. [abstract; full-text (pdf 647K)] (File Cabinet, EB Journal Club)
  • Gupta K, Gupta VK, Jayashree M, Singhi S. Randomized controlled trial of interrupted versus continuous sedative infusions in ventilated children. Pediatr Crit Care Med 2012; 13:131–135. [abstract] (File Cabinet, EB Journal Club)
  • Tyrrell CT, Bateman ST. Critically ill children: To transfuse or not to transfuse packed red blood cells, that is the question. Pediatr Crit Care Med 2012; 13:204–209. [abstract] (File Cabinet)
  • Payen V, Jouvet P, Lacroix J, Ducruet T, Gauvin F. Risk factors associated with increased length of mechanical ventilation in children. Pediatr Crit Care Med.2012; 13:152–157. [abstract] (File Cabinet, EB Journal Club)
  • De Backer D, Aldecoa C, Njimi H, Vincent JL. Dopamine versus norepinephrine in the treatment of septic shock: A meta-analysis*. Crit Care Med. 2012 Mar;40(3):725-30. [abstract] (File Cabinet, EB Journal Club)
  • Wind J, Snoeijs MG, Brugman CA, Vervelde J, Zwaveling J, van Mook WN, van Heurn EL. Prediction of time of death after withdrawal of life-sustaining treatment in potential donors after cardiac death*. Crit Care Med. 2012 Mar;40(3):766-9. [abstract] (File Cabinet, EB Journal Club)
  • Coopersmith CM, Wunsch H, Fink MP, Linde-Zwirble WT, Olsen KM, Sommers MS, Anand KJ, Tchorz KM, Angus DC, Deutschman CS. A comparison of critical care research funding and the financial burden of critical illness in the United States. Crit Care Med. 2012; 40:–1079. [abstract] (File Cabinet)
  • Khemani RG, Thomas NJ, Venkatachalam V, Scimeme JP, Berutti T, Schneider JB, Ross PA, Willson DF, Hall MW, Newth CJ; Pediatric Acute Lung Injury and Sepsis Network Investigators (PALISI). Comparison of SpO2 to PaO2 based markers of lung disease severity for children with acute lung injury. Crit Care Med. 2012; 40(4):1309-1316. [abstract] (File Cabinet, EB Journal Club)
  • Grant MJ, Scoppettuolo LA, Wypij D, Curley MA; for the RESTORE Investigative Team. Prospective evaluation of sedation-related adverse events in pediatric patients ventilated for acute respiratory failure* Crit Care Med. 2012 Apr;40(4):1317-1323. [abstract] (File Cabinet, EB Journal Club)

February 2012

  • Banner MJ, Euliano NR, Martin AD, Al-Rawas N, Layon AJ, Gabrielli A. Noninvasive work of breathing improves prediction of post-extubation outcome. Intensive Care Med. 2012 Feb;38(2):248-55. [abstract] (File Cabinet, EB Journal Club)
  • Burbano NH, Otero AV, Berry DE, Orr RA, Munoz RA. Discontinuation of prolonged infusions of dexmedetomidine in critically ill children with heart disease. Intensive Care Med. 2012 Feb;38(2):300-7. [abstract] (File Cabinet)
  • Pasquali SK, Li JS, Burstein DS, Sheng S, O'Brien SM, Jacobs ML, Jaquiss RD, Peterson ED, Gaynor JW, Jacobs JP. Association of Center Volume With Mortality and Complications in Pediatric Heart Surgery. Pediatrics. 2012;129;e370 [abstract] (File Cabinet, EB Journal Club)
  • Chen JM, Richmond ME, Charette K, Takayama H, Williams M, Gilmore L, Garcia A, Addonizio LJ. A decade of pediatric mechanical circulatory support before and after cardiac transplantation. J Thorac Cardiovasc Surg. 2012 Feb;143(2):344-51 [abstract] (File Cabinet, EB Journal Club)
  • The 19th Pediatric Critical Care Colloquium, sponsored by Critical Care Medicine at Children's Hospital Los Angeles will be held at the Loews Santa Monica Beach Hotel, Santa Monica, California, September 7-9, 2012. Abstract deadline is July 1, 2012. See our website for more information. A preliminary brochure is here... (pdf; 429K) Exhibitor information is here... (pdf; 355K)
  • From the 2012 41st Critical Care Congress in Houston: SCCM Pediatric Section Business meeting minutes/presentations are available here... (pdf; 8.8 MB) (Organizations/Meetings)
  • Monagle P, Chan AKC, Godlenberg NA, Ichord RN, Journeycake JM, Nowak-Gottl U, Vesely SK Antithrombotic Therapy in Neonates and Children: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012;141 e737S-e801S [abstract] (File Cabinet)
  • Tagin MA, Woolcott CG, Vincer MJ, Whyte RK, Stinson DA. Hypothermia for Neonatal Hypoxic Ischemic Encephalopathy: An Updated Systematic Review and Meta-analysis. Arch Pediatr Adolesc Med.2012 Feb 6. [Epub ahead of print] [abstract] (File Cabinet, EB Journal Club)
  • The National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. Initial Trophic vs Full Enteral Feeding in Patients With Acute Lung Injury: The EDEN Randomized Trial. JAMA. 2012;307:832-842 [abstract] (File Cabinet, EB Journal Club)

January 2012

  • Ghuman AK, Newth CJ, Khemani RG. The association between the end tidal alveolar dead space fraction and mortality in pediatric acute hypoxemic respiratory failure. Pediatr Crit Care Med. 2012; 13:11–15 [abstract] (File Cabinet, EB Journal Club)
  • Kanter RK. Pediatric mass critical care in a pandemic. Pediatr Crit Care Med 2012; 13:e1– e4. [abstract] (File Cabinet)
  • Crittendon I 3rd, Dreyer WJ, Decker JA, Kim JJ. Ultrasound dilution: An accurate means of determining cardiac output in children. Pediatr Crit Care Med. 2012; 13:42–46. [abstract] (File Cabinet, EB Journal Club)
  • Zhang Z, Hongying N. Efficacy and safety of regional citrate anticoagulation in critically ill patients undergoing continuous renal replacement therapy. Intensive Care Med. 2012 Jan;38(1):20-8 [abstract] (File Cabinet, EB Journal Club)
  • SCCM Pediatric Section Business meeting (and reception!) schedule for the upcoming 41st Critical Care Congress in Houston is available here... (pdf; 37K) (Organizations/Meetings)
  • An updated version of the 2003 edition: "Guidelines for the Acute Medical Management of Severe Traumatic Brain Injury in Infants, Children, and Adolescents" is now freely available online here... (link to table of contents) (Pediatric Critical Care Medicine. January 2012 - volume 13 - supplement 1_suppl) (File Cabinet)
  • Willmitch B, Golembeski S, Kim SS, Nelson LD, Gidel L. Clinical outcomes after telemedicine intensive care unit implementation*. Crit Care Med. 2012 Feb;40(2):450-4. [abstract] (File Cabinet, EB Journal Club)
  • Zhan Q, Sun B, Liang L, Yan X, Zhang L, Yang J, Wang L, Ma Z, Shi L, Wei L, Li G, Yang L, Shi Z, Chen Y, Xu Q, Li W, Zhu X, Wang Z, Sun Y, Zhuo J, Liu Y, Li X, Wang C. Early use of noninvasive positive pressure ventilation for acute lung injury: A multicenter randomized controlled trial* Crit Care Med. 2012 Feb;40(2):455-460. [abstract] (File Cabinet, EB Journal Club)
  • Landoni G, Biondi-Zoccai G, Greco M, Greco T, Bignami E, Morelli A, Guarracino F, Zangrillo A. Effects of levosimendan on mortality and hospitalization. A meta-analysis of randomized controlled studies*. Crit Care Med. 2012 Feb;40(2):634-46. [abstract] (File Cabinet, EB Journal Club)
  • Melendez E, Goldstein AM, Sagar P, Badizadegan K. Case 3-2012 — A Newborn Boy with Vomiting, Diarrhea, and Abdominal Distention. N Engl J Med 2012; 366:361-372 [full-text] (Case Reports)
  • Domico MB, Ridout DA, Bronicki R, Anas NG, Cleary JP, Cappon J, Goldman AP, Brown KL. The impact of mechanical ventilation time before initiation of extracorporeal life support on survival in pediatric respiratory failure: A review of the extracorporeal life support registry*. Pediatr Crit Care Med. 2012 Jan;13(1):16-21. [abstract; full-text (pdf; 425K)] (File Cabinet, EB Journal Club)
  • Billings JA. Humane terminal extubation reconsidered: The role for preemptive analgesia and sedation*. Crit Care Med. 2012 Feb;40(2):625-30. [abstract] (File Cabinet)
  • Truog RD, Brock DW, White DB. Should patients receive general anesthesia prior to extubation at the end of life?*. Crit Care Med. 2012 Feb;40(2):631-3. [abstract] (File Cabinet)
  • Maclaren G, Combes A, Bartlett RH. Contemporary extracorporeal membrane oxygenation for adult respiratory failure: life support in the new era. Intensive Care Med. 2012 Feb;38(2):210-20. [abstract] (File Cabinet)

December 2011

  • Task Force for Pediatric Emergency Mass Critical Care. Deliberations and Recommendations of The Pediatric Emergency Mass Critical Care Task Force 6. Pediatr Crit Care Med 2011; 12:S103-S179 [full-text] (File Cabinet)
  • Brodie D, Bacchetta M. Extracorporeal membrane oxygenation for ARDS in adults. N Engl J Med. 2011 Nov 17;365(20):1905-14. [abstract] (File Cabinet)
  • Randolph AG, Vaughn F, Sullivan R, Rubinson L, Thompson BT, Yoon G, Smoot E, Rice TW, Loftis LL, Helfaer M, Doctor A, Paden M, Flori H, Babbitt C, Graciano AL, Gedeit R, Sanders RC, Giuliano JS, Zimmerman J, Uyeki TM; the Pediatric Acute Lung Injury and Sepsis Investigator's Network and the National Heart, Lung, and Blood Institute ARDS Clinical Trials Network. Critically Ill Children During the 2009-2010 Influenza Pandemic in the United States. Pediatrics. 2011; 128:e1450-e1458 [abstract] (File Cabinet)
  • Pathan N, Burmester M, Adamovic T, Berk M, Ng KW, Betts H, Macrae D, Waddell S, Paul-Clark M, Nuamah R, Mein C, Levin M, Montana G, Mitchell J. Intestinal Injury and Endotoxemia in Children Undergoing Surgery for Congenital Heart Disease. Am J Respir Crit Care Med. 2011;184 1261-1269 [abstract] (File Cabinet)
  • Walsh MA, Merat M, La Rotta G, Joshi P, Joshi V, Tran T, Jarvis S, Caldarone CA, Van Arsdell GS, Redington AN, Kavanagh BP. Airway pressure release ventilation improves pulmonary blood flow in infants after cardiac surgery. Crit Care Med. 2011 Dec;39(12):2599-604. [abstract] (File Cabinet, EB Journal Club)
  • Cheatham ML, Safcsak K. Percutaneous Catheter Decompression in the Treatment of Elevated Intra-abdominal Pressure. Chest. 2011; 140;1428-1435. [abstract] (File Cabinet, EB Journal Club)
  • Kinane TB, Shailam R, Mark EJ. Case 37-2011 — A 9-Month-Old Boy with Recurrent Tachypnea and Respiratory Distress. N Engl J Med 2011; 365:2221-2228 [full-text] (Case Reports)
  • Kim IK, Phrampus E, Sikes K, Pendleton J, Saville A, Corcoran T, Gracely E, Venkataraman S. Helium-oxygen therapy for infants with bronchiolitis: a randomized controlled trial. Arch Pediatr Adolesc Med. 2011 Dec;165(12):1115-22. [abstract] (File Cabinet, EB Journal Club)
  • The December 2011 issue of the AAP Section on Critical Care Newsletter is now available here... (pdf; 1.9MB) (Organizations)
  • Payen JF, Dupuis C, Trouve-Buisson T, Vinclair M, Broux C, Bouzat P, Genty C, Monneret D, Faure P, Chabre O, Bosson JL. Corticosteroid after etomidate in critically ill patients: A randomized controlled trial. Crit Care Med. 2011; 40(1):29-35. [abstract] (File Cabinet, EB Journal Club)
  • The WFPICCS Newsletter, December 25, 2011 (Vol4nr4) is here... (pdf; 242K) (Organizations)
  • Sheth KN, Nutter T, Stein DM, Scalea TM, Bernat JL. Autoresuscitation after asystole in patients being considered for organ donation*. Crit Care Med. 2012 Jan;40(1):158-61. [abstract] (File Cabinet)
  • Bennett TD, Statler KD, Korgenski EK, Bratton SL. Osmolar therapy in pediatric traumatic brain injury*. Crit Care Med. 2012 Jan;40(1):208-15. [abstract] (File Cabinet)
  • Deutschman CS, Ahrens T, Cairns CB, Sessler CN, Parsons PE; for the Critical Care Societies Collaborative USCIITG Task Force on Critical Care Research. Multisociety Task Force for Critical Care Research: Key issues and recommendations* Crit Care Med. 2012 Jan;40(1):254-260. [abstract] (File Cabinet)

November 2011

  • Important announcements from SCCM Pediatric Section Chair, Jeff Burns are here... (Organizations)
  • Nseir S, Zerimech F, Fournier C, Lubret R, Ramon P, Durocher A, Balduyck M. Continuous Control of Tracheal Cuff Pressure and Microaspiration of Gastric Contents in Critically Ill Patients. Am J Respir Crit Care Med. 2011; 184:1041-1047 [abstract] (File Cabinet, EB Journal Club)
  • Flick RP, Katusic SK, Colligan RC, Wilder RT, Voigt RG, Olson MD, Sprung J, Weaver AL, Schroeder DR, Warner DO. Cognitive and Behavioral Outcomes After Early Exposure to Anesthesia and Surgery. Pediatrics. 2011;128 e1053-e1061. [abstract] (File Cabinet)
  • Miller MR, Niedner MF, Huskins WC, Colantuoni E, Yenokyan G, Moss M, Rice TB, Ridling D, Campbell D, Brilli RJ; the National Association of Children's Hospitals and Related Institutions Pediatric Intensive Care Unit Central Line–Associated Bloodstream Infection Quality Transformation Teams. Reducing PICU Central Line-Associated Bloodstream Infections: 3-Year Results. Pediatrics. 2011;128 e1077-e1083. [abstract] (File Cabinet)
  • Monagle P, Cochrane A, Roberts R, Manlhiot C, Weintraub R, Szechtman B, Hughes M, Andrew M, McCrindle BW; Fontan Anticoagulation Study Group. A multicenter, randomized trial comparing heparin/warfarin and acetylsalicylic acid as primary thromboprophylaxis for 2 years after the Fontan procedure in children. J Am Coll Cardiol. 2011 Aug 2;58(6):645-51. [abstract] (File Cabinet, EB Journal Club)
  • Ferguson LP, Walsh BK, Munhall D, Arnold JH. A spontaneous breathing trial with pressure support overestimates readiness for extubation in children. Pediatr Crit Care Med. 2011; 12:e330 – e335 [abstract; full-text (418K)] (File Cabinet, EB Journal Club)
  • Singer K, Subbaiah P, Hutchinson R, Odetola F, Shanley TP. Clinical course of sepsis in children with acute leukemia admitted to the pediatric intensive care unit. Pediatr Crit Care Med. 2011; 12(6):649-654 [abstract] (File Cabinet, EB Journal Club)
  • James CS, Hallewell CP, James DP, Wade A, Mok QQ. Predicting the success of non-invasive ventilation in preventing intubation and re-intubation in the paediatric intensive care unit. Intensive Care Med. 2011 Dec;37(12):1994-2001 [abstract] (File Cabinet, EB Journal Club)
  • Essouri S, Durand P, Chevret L, Balu L, Devictor D, Fauroux B, Tissières P. Optimal level of nasal continuous positive airway pressure in severe viral bronchiolitis. Intensive Care Med. 2011 Dec;37(12):2002-7. [abstract] (File Cabinet)

October 2011

  • Oster ME, Strickland MJ, Mahle WT. Impact of prior hospital mortality versus surgical volume on mortality following surgery for congenital heart disease. J Thorac Cardiovasc Surg. 2011;142:882-6. [abstract] (File Cabinet, EB Journal Club)
  • Nitta M, Iwami T, Kitamura T, Nadkarni VM, Berg RA, Shimizu N, Ohta K, Nishiuchi T, Hayashi Y, Hiraide A, Tamai H, Kobayashi M, Morita H; for the Utstein Osaka Project. Age-Specific Differences in Outcomes After Out-of-Hospital Cardiac Arrests. Pediatrics. 2011; 128:e812 [abstract] (File Cabinet, EB Journal Club)
  • Marini JJ. Dynamic Hyperinflation and Auto-PEEP: Lessons Learned Over Thirty Years. Am J Respir Crit Care Med. 2011; 184:756–762. [abstract] (File Cabinet)
  • Aneja R, Carcillo J. Differences between adult and pediatric septic shock. Minerva Anestesiol. 2011 Oct;77(10):986-92. [abstract] (File Cabinet)
  • The INIS Collaborative Group. Treatment of neonatal sepsis with intravenous immune globulin. N Engl J Med. 2011 Sep 29;365(13):1201-11. [abstract] (File Cabinet, EB Journal Club)
  • Rice TW, Wheeler AP, Thompson BT, Deboisblanc BP, Steingrub J, Rock P; for the NHLBI ARDS Clinical Trials Network. Enteral Omega-3 Fatty Acid, {gamma}-Linolenic Acid, and Antioxidant Supplementation in Acute Lung Injury. JAMA. 2011;306 1574-1581 [abstract] (File Cabinet, EB Journal Club)
  • Noah MA, Peek GJ, Finney SJ, Griffiths MJ, Harrison DA, Grieve R, Sadique MZ, Sekhon JS, McAuley DF, Firmin RK, Harvey C, Cordingley JJ, Price S, Vuylsteke A, Jenkins DP, Noble DW, Bloomfield R, Walsh TS, Perkins GD, Menon D, Taylor BL, Rowan KM. Referral to an Extracorporeal Membrane Oxygenation Center and Mortality Among Patients With Severe 2009 Influenza A(H1N1). JAMA. 2011;306 1659-1668. [abstract] (File Cabinet, EB Journal Club)
  • Raimer PL, Han YY, Weber MS, Annich GM, Custer JR. A normal capillary refill time of ≤ 2 seconds is associated with superior vena cava oxygen saturations of ≥ 70%. J Pediatr. 2011 Jun;158(6):968-72. [abstract] (File Cabinet, EB Journal Club)
  • Levine M, Brooks DE, Truitt CA, Wolk BJ, Boyer EW, Ruha AM. Toxicology in the ICU: Part 1: General Overview and Approach to Treatment. Chest. 2011 Sep;140(3):795-806. [abstract](File Cabinet)
  • Brooks DE, Levine M, O'Connor AD, French RN, Curry SC. Toxicology in the ICU: Part 2: Specific Toxins. Chest. 2011 Oct;140(4):1072-85. [abstract] (File Cabinet)
  • Wong HR, Cvijanovich NZ, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Lin R, Shanley TP, Bigham MT, Wheeler DS, Doughty LA, Tegtmeyer K, Poynter SE, Kaplan JM, Chima RS, Stalets E, Basu RK, Varisco BM, Barr FE. Validation of a gene expression-based subclassification strategy for pediatric septic shock. Crit Care Med. 2011; 39:2511–2517. [abstract] (File Cabinet)
  • Foronda FA, Troster EJ, Farias JA, Barbas CS, Ferraro AA, Faria LS, Bousso A, Panico FF, Delgado AF. The impact of daily evaluation and spontaneous breathing test on the duration of pediatric mechanical ventilation: A randomized controlled trial. Crit Care Med. 2011. 39:2526–2533. [abstract] (File Cabinet, EB Journal Club)
  • Pastores SM, Oconnor MF, Kleinpell RM, Napolitano L, Ward N, Bailey H, Mollenkopf FP Jr, Coopersmith CM. The Accreditation Council for Graduate Medical Education resident duty hour new standards: History, changes, and impact on staffing of intensive care units. Crit Care Med. 2011. 39:2540 –2549. [abstract] (File Cabinet)
  • Khemani RG, Sward K, Morris A, Dean JM, Newth CJ; On behalf of the NICHD Collaborative Pediatric Critical Care Research Network (CPCCRN). Variability in usual care mechanical ventilation for pediatric acute lung injury: the potential benefit of a lung protective computer protocol. Intensive Care Med. 2011 Nov;37(11):1840-1848. [abstract] (File Cabinet)
  • Choong K, Arora S, Cheng J, Farrokhyar F, Reddy D, Thabane L, Walton JM. Hypotonic Versus Isotonic Maintenance Fluids After Surgery for Children: A Randomized Controlled Trial. Pediatrics. 2011 128 857-866 [abstract] (File Cabinet, EB Journal Club)
  • Important announcements from SCCM Pediatric Section Chair, Jeff Burns are here... (Organizations)

September 2011

  • Nakagawa TA, Ashwal S, Mathur M, Mysore MR, Bruce D, Conway EE Jr, Duthie SE, Hamrick S, Harrison R, Kline AM, Lebovitz DJ, Madden MA, Montgomery VL, Perlman JM, Rollins N, Shemie SD, Vohra A, Williams-Phillips JA; Society of Critical Care Medicine; the Section on Critical Care and Section on Neurology of the American Academy of Pediatrics; the Child Neurology Society. Guidelines for the determination of brain death in infants and children: An update of the 1987 Task Force recommendations. Crit Care Med. 2011 Sep;39(9):2139-2155. [abstract] (File Cabinet)
  • Grunwald IQ, Walter S, Fassbender K, KĂĽhn AL, Hartmann KM, Wilson N, Sievert H, Kamran M, Hopkins LN, Wakhloo AK. Ischemic stroke in children: new aspects of treatment. J Pediatr. 2011 Sep;159(3):366-70. [citation] (File Cabinet)
  • Hosokawa K, Shime N, Kato Y, Taniguchi A, Maeda Y, Miyazaki T, Hashimoto S. Dexmedetomidine sedation in children after cardiac surgery. Pediatr Crit Care Med. 2010 Jan;11(1):39-43. [abstract] (File Cabinet, EB Journal Club)
  • Matthay MA, Brower RG, Carson S, Douglas IS, Eisner M, Hite D, Holets S, Kallet RH, Liu KD, Macintyre N, Moss M, Schoenfeld D, Steingrub J, Thompson BT; The National Heart, Lung, and Blood Institute ARDS Clinical Trials Network. Randomized, Placebo-Controlled Clinical Trial of an Aerosolized Beta-2 Agonist for Treatment of Acute Lung Injury. Am J Respir Crit Care Med. 2011;184 561-568. [abstract] (File Cabinet, EB Journal Club)
  • Kissoon N, Carcillo JA, Espinosa V, Argent A, Devictor D, Madden M, Singhi S, van der Voort E, Latour J; the Global Sepsis Initiative Vanguard Center Contributors. World Federation of Pediatric Intensive Care and Critical Care Societies: Global Sepsis Initiative. Pediatr Crit Care Med. 2011 Sep;12(5):494-503. [abstract; full-text (1.2MB)] (File Cabinet)
  • Karam O, Tucci M, Ducruet T, Hume HA, Lacroix J, Gauvin F; for the Canadian Critical Care Trials Group and the PALISI Network. Red blood cell transfusion thresholds in pediatric patients with sepsis. Pediatr Crit Care Med. 2011 Sep;12(5):512-518. [abstract] (File Cabinet, EB Journal Club)
  • van der Wal J, van Heerde M, Markhorst DG, Kneyber MC. Transfusion of leukocyte-depleted red blood cells is not a risk factor for nosocomial infections in critically ill children. Pediatr Crit Care Med. 2011 Sep;12(5):519-24. [abstract] (File Cabinet, EB Journal Club)
  • Weiss CH, Moazed F, McEvoy CA, Singer BD, Szleifer I, Amaral LA, Kwasny M, Watts CM, Persell SD, Baker DW, Sznajder JI, Wunderink RG. Prompting Physicians to Address a Daily Checklist and Process of Care and Clinical Outcomes: A Single-Site Study. Am J Respir Crit Care Med. 2011; 184:680–686. [abstract] (File Cabinet, EB Journal Club)

August 2011

  • Ginther R, Sebastian VA, Huang R, Leonard SR, Gorney R, Guleserian KJ, Forbess JM. Cerebral near-infrared spectroscopy during cardiopulmonary bypass predicts superior vena cava oxygen saturation. J Thorac Cardiovasc Surg. 2011 Aug;142(2):359-65. [abstract] (File Cabinet)
  • An outstanding collection of radiologic teaching files, from John J. Mickell, M.D., former Professor and Chairman Division of Pediatric Critical Care Medicine Children's Medical Center Virginia Commonwealth University Health System, Richmond VA. [powerpoint file; 47 MB!] (File Cabinet)
  • Jacobs SE, Morley CJ, Inder TE, Stewart MJ, Smith KR, McNamara PJ, Wright IM, Kirpalani HM, Darlow BA, Doyle LW; for the Infant Cooling Evaluation Collaboration. Whole-Body Hypothermia for Term and Near-Term Newborns With Hypoxic-Ischemic Encephalopathy: A Randomized Controlled Trial. Arch Pediatr Adolesc Med. 2011;165(8):692-700. [abstract] (File Cabinet, EB Journal Club)
  • Hospital Pediatrics, a new scholarly journal from the AAP dedicated to hospital pediatrics. (Journals)
  • The American Academy of Pediatrics (AAP) Disaster Preparedness Newsletters are here... (Organizations)
  • Casaer MP, Mesotten D, Hermans G, Wouters PJ, Schetz M, Meyfroidt G, Van Cromphaut S, Ingels C, Meersseman P, Muller J, Vlasselaers D, Debaveye Y, Desmet L, Dubois J, Van Assche A, Vanderheyden S, Wilmer A, Van den Berghe G. Early versus Late Parenteral Nutrition in Critically Ill Adults. N Engl J Med. 2011;365:506-17. [abstract] (File Cabinet, EB Journal Club)
  • Portman MA, Slee A, Olson AK, Cohen G, Karl T, Tong E, Hastings L, Patel H, Reinhartz O, Mott AR, Mainwaring R, Linam J, Danzi S; TRICC Investigators. Triiodothyronine Supplementation in Infants and Children Undergoing Cardiopulmonary Bypass (TRICC): a multicenter placebo-controlled randomized trial: age analysis. Circulation. 2010 Sep 14;122(11 Suppl):S224-33. [abstract] (File Cabinet, EB Journal Club)
  • There are new resource materials available on the WFPICCS website here... Includes summaries of the latest research on child health in developing countries: evidence derived from all the randomized trials published over the last year. (Organizations)
  • Peñuelas O, Frutos-Vivar F, Fernández C, Anzueto A, Epstein SK, ApezteguĂ­a C, González M, Nin N, Raymondos K, Tomicic V, Desmery P, Arabi Y, Pelosi P, Kuiper M, Jibaja M, Matamis D, Ferguson ND, Esteban A; for the Ventila Group. Characteristics and Outcomes of Ventilated Patients According to Time to Liberation from Mechanical Ventilation. Am J Respir Crit Care Med. 2011; 184:430-437. [abstract] (File Cabinet, EB Journal Club)
  • Hess DR, Macintyre NR. Ventilator discontinuation: why are we still weaning? Am J Respir Crit Care Med. 2011; 184:392-394. (editorial) [citation] (File Cabinet)
  • Torgersen C, Luckner G, Schröder DC, Schmittinger CA, Rex C, Ulmer H, DĂĽnser MW. Concomitant arginine-vasopressin and hydrocortisone therapy in severe septic shock: association with mortality. Intensive Care Med. 2011 Sep;37(9):1432-7. [abstract] (File Cabinet, EB Journal Club)
  • Piastra M, De Luca D, Marzano L, Stival E, Genovese O, Pietrini D, Conti G. The number of failing organs predicts non-invasive ventilation failure in children with ALI/ARDS. Intensive Care Med. 2011 Sep;37(9):1510-6. [abstract] (File Cabinet, EB Journal Club)
  • Puskarich MA, Trzeciak S, Shapiro NI, Arnold RC, Horton JM, Studnek JR, Kline JA, Jones AE; on behalf of the Emergency Medicine Shock Research Network (EMSHOCKNET). Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol. Crit Care Med. 2011 Sep;39(9):2066-2071. [abstract] (File Cabinet, EB Journal Club)

July 2011

  • Boriosi JP, Sapru A, Hanson JH, Asselin J, Gildengorin G, Newman V, Sabato K, Flori HR. Efficacy and safety of lung recruitment in pediatric patients with acute lung injury. Pediatr Crit Care Med. 2011; 12:431–436 [abstract; full-text (pdf; 500K)] (File Cabinet)
  • Vats A, Goin KH, Fortenberry JD. Lean analysis of a pediatric intensive care unit physician group rounding process to identify inefficiencies and opportunities for improvement. Pediatr Crit Care Med. 2011; 12:415–421 [abstract] (File Cabinet)
  • Fragou M, Gravvanis A, Dimitriou V, Papalois A, Kouraklis G, Karabinis A, Saranteas T, Poularas J, Papanikolaou J, Davlouros P, Labropoulos N, Karakitsos D. Real-time ultrasound-guided subclavian vein cannulation versus the landmark method in critical care patients: A prospective randomized study. Crit Care Med. 2011 Jul;39(7):1607-1612. [abstract] (File Cabinet, EB Journal Club)
  • The latest WFPICCS Newsletter: July 15th, 2011/Volume 4 /Number 2 (pdf; 250K)
  • (Organizations)
  • NIH Clinical Center Grand Rounds: Steroids in Sepsis - Review of Clinical Trials and Preclinical Studies in a Canine Model. Charles Natanson, MD, Senior Investigator and Chief, Anesthesia Section, Critical Care Medicine Department, NIH Clinical Center, and Peter Minneci, MD, Instructor in Surgery, Chief Surgical Resident, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine. video (52 min) (File Cabinet)
  • The CDC has released the following document: Ethical Considerations for Decision Making Regarding Allocation of Mechanical Ventilators during a Severe Influenza Pandemic or Other Public Health Emergency (File Cabinet)
  • Jones DA, DeVita MA, Bellomo R. Rapid-response teams. N Engl J Med. 2011 Jul 14;365(2):139-46. [citation] (File Cabinet)
  • Williams AM, Abramo TJ, Shah MV, Miller RA, Burney-Jones C, Rooks S, Estrada C, Arnold DH. Safety and clinical findings of BiPAP utilization in children 20 kg or less for asthma exacerbations. Intensive Care Med. 2011 Aug;37(8):1338-43. [abstract] (File Cabinet, EB Journal Club)
  • Janssen NJ, Tan EY, Staal M, Janssen EP, Leroy PL, Lousberg R, van Os J, Schieveld JN. On the utility of diagnostic instruments for pediatric delirium in critical illness: an evaluation of the Pediatric Anesthesia Emergence Delirium Scale, the Delirium Rating Scale 88, and the Delirium Rating Scale-Revised R-98. Intensive Care Med. 2011 Aug;37(8):1331-7. [abstract] (File Cabinet, EB Journal Club)
  • Muscedere J, Rewa O, McKechnie K, Jiang X, Laporta D, Heyland DK. Subglottic secretion drainage for the prevention of ventilator-associated pneumonia: A systematic review and meta-analysis. Crit Care Med. 2011; 39:1985–1991. [abstract] (File Cabinet, EB Journal Club)

June 2011

  • Albert SG, Ariyan S, Rather A. The effect of etomidate on adrenal function in critical illness: a systematic review. Intensive Care Med. 2011 Jun;37(6):901-10. [abstract] (File Cabinet, EB Journal Club)
  • Burstein DS, Jacobs JP, Li JS, Sheng S, O'Brien SM, Rossi AF, Checchia PA, Wernovsky G, Welke KF, Peterson ED, Jacobs ML, Pasquali SK. Care models and associated outcomes in congenital heart surgery. Pediatrics. 2011 Jun;127(6):e1482-9. [abstract] (File Cabinet, EB Journal Club)
  • Levy FH, Brilli RJ, First LR, Hyman D, Kohrt AE, Ludwig S, Miles PV, Saffer M. A New Framework for Quality Partnerships in Children's Hospitals. Pediatrics. 2011 Jun;127(6):1147-56. [abstract] (File Cabinet)
  • Larsen GY, Mecham N, Greenberg R. An emergency department septic shock protocol and care guideline for children initiated at triage. Pediatrics. 2011 Jun;127(6):e1585-92. [abstract] (File Cabinet)
  • Mastropietro CW, Valentine K. Early administration of intratracheal surfactant (calfactant) after hydrocarbon aspiration. Pediatrics. 2011 Jun;127(6):e1600-4. [abstract] (Case Reports)
  • Applications are now open for the Pediatric Critical Care Scientist Development Program (PCCSDP). Read more here... (Clinical Research)
  • Maitland K, Kiguli S, Opoka RO, Engoru C, Olupot-Olupot P, Akech SO, Nyeko R, Mtove G, Reyburn H, Lang T, Brent B, Evans JA, Tibenderana JK, Crawley J, Russell EC, Levin M, Babiker AG, Gibb DM; the FEAST Trial Group. Mortality after Fluid Bolus in African Children with Severe Infection. N Engl J Med. 2011;364:2483-2495 [abstract] (File Cabinet, EB Journal Club)
  • van Woensel JB, Vyas H; on behalf of the STAR Trial Group. Dexamethasone in children mechanically ventilated for lower respiratory tract infection caused by respiratory syncytial virus: A randomized controlled trial. Crit Care Med. 2011; 39:1779 –1783 [abstract] (File Cabinet, EB Journal Club)
  • Sorce L, Simone S, Madden M. Educational preparation and post graduate training curriculum for pediatric critical care nurse practitioners* Pediatr Crit Care Med 11:205–212 [abstract; full-text (pdf 197K)]: Now available: Appendix B: Orientation Checklist (pdf; 134K) [ "This information is intended for the Public Domain and access is allowed by the authors (L. Sorce, S. Simone and M. Madden)" ] (Nursing)

May 2011

  • Faustino EV, Lawson KA, Northrup V, Higgerson RA. Mortality-adjusted duration of mechanical ventilation in critically ill children with symptomatic central venous line-related deep venous thrombosis. Crit Care Med. 2011; 39:1151–1156 [abstract] (File Cabinet, EB Journal Club)
  • Brun-Buisson C, Richard JC, Mercat A, ThiĂ©baut AC, Brochard L; for the REVA-SRLF A/H1N1v 2009 Registry Group. Early Corticosteroids in Severe Influenza A/H1N1 Pneumonia and Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2011; 183:1200-1206. [abstract] (File Cabinet, EB Journal Club)
  • Kim SH, Hong SB, Yun SC, Choi WI, Ahn JJ, Lee YJ, Lee HB, Lim CM, Koh Y; for the Korean Society of Critical Care Medicine H1N1 Collaborative. Corticosteroid Treatment in Critically Ill Patients with Pandemic Influenza A/H1N1 2009 Infection: Analytic Strategy using Propensity Scores. Am J Respir Crit Care Med. 2011; 183:1207-1214. [abstract] (File Cabinet, EB Journal Club)
  • Stockwell JA, Pham N, Fortenberry JD. Impact of a computerized note template/checklist on documented adherence to institutional criteria for determination of neurologic death in a pediatric intensive care unit. Pediatr Crit Care Med. 2011; 12:271–276 [abstract] (File Cabinet)
  • Venkatachalam V, Hendley JO, Willson DF. The diagnostic dilemma of ventilator-associated pneumonia in critically ill children. Pediatr Crit Care Med 2011; 12:286-296. [abstract; full-text (pdf; 983K)] (File Cabinet)
  • Zavalkoff SR, Razack SI, Lavoie J, Dancea AB. Handover after pediatric heart surgery: A simple tool improves information exchange. Pediatr Crit Care Med. 2011; 12:304-308. [abstract] (File Cabinet)
  • Joy BF, Elliott E, Hardy C, Sullivan C, Backer CL, Kane JM. Standardized multidisciplinary protocol improves handover of cardiac surgery patients to the intensive care unit. Pediatr Crit Care Med. 2011; 12:304–308. [abstract] (File Cabinet)
  • Li S, Krawczeski CD, Zappitelli M, Devarajan P, Thiessen-Philbrook H, Coca SG, Kim RW, Parikh CR; for the TRIBE-AKI Consortium. Incidence, risk factors, and outcomes of acute kidney injury after pediatric cardiac surgery: A prospective multicenter study* Crit Care Med. 2011 39:1493–1499 [abstract] (File Cabinet, EB Journal Club)
  • Webb AC, Samuels OB. Reversible brain death after cardiopulmonary arrest and induced hypothermia. Crit Care Med. 2011; 39: 1538 –1542. [abstract] (Case Reports, File Cabinet)
  • Lilly CM, Cody S, Zhao H, Landry K, Baker SP, McIlwaine J, Chandler MW, Irwin RS; for the University of Massachusetts Memorial Critical Care Operations Group. Hospital Mortality, Length of Stay, and Preventable Complications Among Critically Ill Patients Before and After Tele-ICU Reengineering of Critical Care Processes. 2011;305(21):doi:10.1001/jama.2011.697 May 16. [Epub ahead of print] [abstract] (File Cabinet, EB Journal Club)

April 2011

  • Hollenberg SM. Vasoactive Drugs in Circulatory Shock. Am J Respir Crit Care Med 2011; 183: 847-855. [abstract] (File Cabinet)
  • Borgman MA, Maegele M, Wade CE, Blackbourne LH, Spinella PC. Pediatric Trauma BIG Score: Predicting Mortality in Children After Military and Civilian Trauma. Pediatrics. 2011; 127 e892-e897. [abstract] (File Cabinet, EB Journal Club)
  • Kleinpell R, Ely EW, Williams G, Liolios A, Ward N, Tisherman SA. Web-based resources for critical care education. Crit Care Med. 2011 Mar;39(3):541-53. [abstract] (File Cabinet)
  • Kamel H, Navi BB, Nakagawa K, Hemphill JC 3rd, Ko NU. Hypertonic saline versus mannitol for the treatment of elevated intracranial pressure: a meta-analysis of randomized clinical trials. Crit Care Med. 2011 Mar;39(3):554-9. [abstract] (File Cabinet, EB Journal Club)
  • Annane D, Chadda K, Gajdos P, Jars-Guincestre MC, Chevret S, Raphael JC Hyperbaric oxygen therapy for acute domestic carbon monoxide poisoning: two randomized controlled trials. Intensive Care Med. 2011 Mar;37(3):486-92. [abstract] (File Cabinet, EB Journal Club)
  • Fraisse A, Butrous G, Taylor MB, Oakes M, Dilleen M, Wessel DL. Intravenous sildenafil for postoperative pulmonary hypertension in children with congenital heart disease. Intensive Care Med. 2011 Mar;37(3):502-9 [abstract] (File Cabinet, EB Journal Club)
  • Hall MW, Knatz NL, Vetterly C, Tomarello S, Wewers MD, Volk HD, Carcillo JA. Immunoparalysis and nosocomial infection in children with multiple organ dysfunction syndrome. Intensive Care Med. 2011 Mar;37(3):525-32 [abstract] (File Cabinet)
  • Maclaren G, Butt W, Best D, Donath S. Central extracorporeal membrane oxygenation for refractory pediatric septic shock. Pediatr Crit Care Med. 2011; 12:133–136 [abstract] (File Cabinet, EB Journal Club)
  • Czaja AS, Scanlon MC, Kuhn EM, Jeffries HE. Performance of the Pediatric Index of Mortality 2 for pediatric cardiac surgery patients. Pediatr Crit Care Med 2011; 12:184 –189. [abstract] (File Cabinet)
  • Karam O, Tucci M, Ducruet T, Hume HA, Lacroix J, Gauvin F; for the Canadian Critical Care Trials Group and the PALISI Network. Red blood cell transfusion thresholds in pediatric patients with sepsis. Pediatr Crit Care Med. 2011; 12(5): [2010 Nov 4. Epub ahead of print] doi: 10.1097/PCC.0b013e3181fe344b [abstract] (File Cabinet, EB Journal Club)
  • Spragg RG, Taut FJ, Lewis JF, Schenk P, Ruppert C, Dean N, Krell K, Karabinis A, GĂĽnther A. Recombinant Surfactant Protein C Based Surfactant for Patients with Severe Direct Lung Injury. Am J Respir Crit Care Med 2011; 183: 1055–1061. [abstract] (File Cabinet, EB Journal Club)
  • Charron C, Bouferrache K, Caille V, Castro S, Aegerter P, Page B, Jardin F, Vieillard-Baron A. Routine prone positioning in patients with severe ARDS: feasibility and impact on prognosis. Intensive Care Med. 2011 May;37(5):785-90. [abstract] (File Cabinet, EB Journal Club)
  • Schibler A, Pham TM, Dunster KR, Foster K, Barlow A, Gibbons K, Hough JL. Reduced intubation rates for infants after introduction of high-flow nasal prong oxygen delivery. Intensive Care Med. 2011 May;37(5):847-52. [abstract] (File Cabinet, EB Journal Club)
  • Sivarajan VB, Best D, Brizard CP, Shekerdemian LS, d'Udekem Y, Butt W. Duration of resuscitation prior to rescue extracorporeal membrane oxygenation impacts outcome in children with heart disease. Intensive Care Med. 2011 May;37(5):853-60. [abstract] (File Cabinet, EB Journal Club)
  • Minutes from the January 2011 APN Subcommittee of the Pediatric Section of SCCM are here... (pdf; 96K) (Meetings)
  • See the latest WFPICCS Newsletter: April 15th, 2011/Volume 4 /Number 1 (pdf; 250K)
  • Istaphanous GK, Wheeler DS, Lisco SJ, Shander A. Red blood cell transfusion in critically ill children: A narrative review. Pediatr Crit Care Med 2011; 12:174 –183. [abstract; full-text (pdf;246K)] (File Cabinet)
  • Hebbar KB, Stockwell JA, Leong T, Fortenberry JD. Incidence of adrenal insufficiency and impact of corticosteroid supplementation in critically ill children with systemic inflammatory syndrome and vasopressor-dependent shock* Crit Care Med. 2011; 39:1145–1150 [abstract] (File Cabinet, EB Journal Club)

March 2011

  • Roquilly A, Mahe PJ, Seguin P, Guitton C, Floch H, Tellier AC, Merson L, Renard B, Malledant Y, Flet L, Sebille V, Volteau C, Masson D, Nguyen JM, Lejus C, Asehnoune K. Hydrocortisone therapy for patients with multiple trauma: the randomized controlled HYPOLYTE study. JAMA. 2011 Mar 23;305(12):1201-9. [abstract] (File Cabinet, EB Journal Club)
  • Le KN, Moffett BS, Ocampo EC, Zaki J, Mossad EB. Impact of dexmedetomidine on early extubation in pediatric cardiac surgical patients. Intensive Care Med. 2011 Apr;37(4):686-90 [abstract] (File Cabinet, EB Journal Club)
  • Cooper DJ, Rosenfeld JV, Murray L, Arabi YM, Davies AR, D'Urso P, Kossmann T, Ponsford J, Seppelt I, Reilly P, Wolfe R; the DECRA Trial Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Decompressive Craniectomy in Diffuse Traumatic Brain Injury. N Engl J Med. 2011 Mar 25. [Epub ahead of print; 10.1056/NEJMoa1102077] [abstract] (File Cabinet, EB Journal Club)
  • Deeter KH, King MA, Ridling D, Irby GL, Lynn AM, Zimmerman JJ. Successful implementation of a pediatric sedation protocol for mechanically ventilated patients. Crit Care Med. 2011; 39:683–688. [abstract] (File Cabinet, EB Journal Club)

February 2011

  • Auerbach SR, Richmond ME, Lamour JM, Blume ED, Addonizio LJ, Shaddy RE, Mahony L, Pahl E, Hsu DT. BNP levels predict outcome in pediatric heart failure patients: post hoc analysis of the Pediatric Carvedilol Trial. Circ Heart Fail. 2010 Sep 1;3(5):606-11. [abstract] (File Cabinet, EB Journal Club)
  • The 2011 CoPS (Council on Pediatric Subspecialities) Winter Newsletter is now available here... (pdf: 115K)
  • Pandemic Influenza in the Pediatric Population: Just in Time Training, by ORISE - Oak Ridge Institute for Science and Education, for the CDC. Corresponding author Ken Tegtmeyer, MD, FAAP, FCCM (File Cabinet)
  • Jaber S, Petrof BJ, Jung B, Chanques G, Berthet JP, Rabuel C, Bouyabrine H, Courouble P, Koechlin-Ramonatxo C, Sebbane M, Similowski T, Scheuermann V, Mebazaa A, Capdevila X, Mornet D, Mercier J, Lacampagne A, Philips A, Matecki S. Rapidly Progressive Diaphragmatic Weakness and Injury during Mechanical Ventilation in Humans. Am J Respir Crit Care Med. 2011 Feb 1;183(3):364-71. [abstract] (File Cabinet)
  • Bazelon E. Shaken-Baby Syndrome Faces New Questions in Court, New York Times Magazine, February 6, 2011. (Timely Issues)
  • The Pediatric Critical Care Colloquium : An independent scientific and educational meeting, now with it's own website: www.pedccc.com (Meetings)

  • 19th Pediatric Critical Care Colloquium, sponsored by Critical Care Medicine at Children's Hospital Los Angeles will be held at the Loews Santa Monica Beach Hotel, Santa Monica, California, September 9-11, 2012. Details to follow.. (Meetings)
  • Craig TR, Duffy MJ, Shyamsundar M, McDowell C, O' Kane C, Elborn JS, McAuley DF. A Randomized Clinical Trial of Hydroxymethylglutaryl-CoA reductase Inhibition for Acute Lung Injury (The HARP study). Am J Respir Crit Care Med 2011; 183:620-626. [abstract] (File Cabinet, EB Journal Club)

January 2011

  • Meaney PA, Nadkarni VM, Atkins DL, Berg MD, Samson RA, Hazinski MF, Berg RA; for the American Heart Association National Registry of Cardiopulmonary Resuscitation Investigators. Effect of Defibrillation Energy Dose During In-Hospital Pediatric Cardiac Arrest. Pediatrics. 2011; 127 e16-e23 [abstract] (File Cabinet)
  • Yung M, Slater A, Festa M, Williams G, Erickson S, Pettila V, Alexander J, Howe BD, Shekerdemian LS; on behalf of the Australia New Zealand Intensive Care Influenza Investigators and the Paediatric Study Groupthe Clinical Trials Group of the Australia New Zealand Intensive Care Society. Pandemic H1N1 in Children Requiring Intensive Care in Australia and New Zealand During Winter 2009. Pediatrics 2011;127 e156-e163 [abstract] (File Cabinet)
  • Stroud MH, Prodhan P, Moss M, Fiser R, Schexnayder S, Anand K. Enhanced Monitoring Improves Pediatric Transport Outcomes: A Randomized Controlled Trial. Pediatrics 2011;127 42-48 [abstract] (File Cabinet, EB Journal Club)
  • Kavanagh BP, McCowen KC. Clinical practice. Glycemic control in the ICU. N Engl J Med. 2010 Dec 23;363(26):2540-6 [citation] (File Cabinet)
  • "Peds Heart," an iPhone app by and for post-operative cardiac surgery ICU nurses. From Shands Healthcare, Inc. iTunes preview description is here... (Software)
  • Khouli H, Jahnes K, Shapiro J, Rose K, Mathew J, Gohil A, Han Q, Sotelo A, Jones J, Aqeel A, Eden E, Fried E. Performance of Medical Residents in Sterile Techniques during Central Vein Catheterization: Randomized Trial of Efficacy of Simulation-Based Training. Chest 2011; 139(1): 80-87 [abstract] (File Cabinet, EB Journal Club)
  • Cholette J, Rubenstein J, Alfieris G, Powers K, Eaton M, Lerner N. Children with single-ventricle physiology do not benefit from higher hemoglobin levels post cavopulmonary connection: Results of a prospective, randomized, controlled trial of a restrictive versus liberal red-cell transfusion strategy. Pediatr Crit Care Med 2011; 12(1): 39-45. [abstract; full-text (pdf;225K)] (File Cabinet, EB Journal Club)
  • Zimmerman JJ, Williams MD. Adjunctive corticosteroid therapy in pediatric severe sepsis: Observations from the RESOLVE study. Pediatr Crit Care Med. 2011 Jan;12(1):2-8. [abstract] (File Cabinet, EB Journal Club)
  • Presentations at the SCCM Pediatric Section Business Meeting, January 18, 2011, in San Diego [pdf; 2 MB]
  • Andreatta P, Saxton E, Thompson M, Annich G. Simulation-based mock codes significantly correlate with improved pediatric patient cardiopulmonary arrest survival rates. Pediatr Crit Care Med. 2011 Jan;12(1):33-8. [abstract] (File Cabinet)
  • McCrory MC, Brady KM, Takemoto C, Tobias JD, Easley RB. Thrombotic disease in critically ill children. Pediatr Crit Care Med. 2011 Jan;12(1):80-9. [abstract] (File Cabinet)
  • Ranjit S, Kissoon N. Dengue hemorrhagic fever and shock syndromes. Pediatr Crit Care Med. 2011 Jan;12(1):90-100. [abstract] (File Cabinet)
  • LearnICU: a new knowledge portal from SCCM. (Organizations)
  • Zabrocki LA, Brogan TV, Statler KD, Poss WB, Rollins MD, Bratton SL. Extracorporeal membrane oxygenation for pediatric respiratory failure: Survival and predictors of mortality. Crit Care Med. 2011 Feb;39(2):364-70. [abstract] (File Cabinet, EB Journal Club)
  • Delaney AP, Dan A, McCaffrey J, Finfer S. The role of albumin as a resuscitation fluid for patients with sepsis: A systematic review and meta-analysis. Crit Care Med. 2011 Feb;39(2):386-91. [abstract] (File Cabinet, EB Journal Club)
  • Cotts T, Hirsch J, Thorne M, Gajarski R. Tracheostomy after pediatric cardiac surgery: Frequency, indications, and outcomes. J Thorac Cardiovasc Surg. 2011 Feb;141(2):413-8. [abstract] (File Cabinet)
  • Scales DC, Dainty K, Hales B, Pinto R, Fowler RA, Adhikari NK, Zwarenstein M. A Multifaceted Intervention for Quality Improvement in a Network of Intensive Care Units: A Cluster Randomized Trial. JAMA. 2011; 305: 363-372[abstract] (File Cabinet)

December 2010

  • Dmello D, Taylor S, O'Brien J, Matuschak GM. Outcomes of Etomidate in Severe Sepsis and Septic Shock. Chest. 2010; 138:1327-1332 [abstract] (File Cabinet, EB Journal Club)
  • Pipeling MR, Fan E. Therapies for refractory hypoxemia in acute respiratory distress syndrome. JAMA. 2010 Dec 8;304(22):2521-7. [abstract] (File Cabinet)
  • WFPICCS Newsletter, December 20th, 2010/Volume 3 /Number 4 (pdf; 336K) (Organizations)
  • Mascia L, Pasero D, Slutsky AS, Arguis MJ, Berardino M, Grasso S, Munari M, Boifava S, Cornara G, Della Corte F, Vivaldi N, Malacarne P, Del Gaudio P, Livigni S, Zavala E, Filippini C, Martin EL, Donadio PP, Mastromauro I, Ranieri VM. Effect of a lung protective strategy for organ donors on eligibility and availability of lungs for transplantation: a randomized controlled trial. JAMA. 2010 Dec 15;304(23):2620-7. [abstract] (File Cabinet, EB Journal Club)
  • Khemani RG, Newth CJ. The design of future pediatric mechanical ventilation trials for acute lung injury. Am J Respir Crit Care Med. 2010 Dec 15;182(12):1465-74. [abstract] (Clinical Research)
  • Moler FW, Donaldson AE, Meert K, Brilli RJ, Nadkarni V, Shaffner DH, Schleien CL, Clark RS, Dalton HJ, Statler K, Tieves KS, Hackbarth R, Pretzlaff R, van der Jagt EW, Pineda J, Hernan L, Dean JM; for the Pediatric Emergency Care Applied Research Network. Multicenter cohort study of out-of-hospital pediatric cardiac arrest. Crit Care Med. 2011; 39:141–149 [abstract] (File Cabinet, EB Journal Club)
  • Smith HA, Boyd J, Fuchs DC, Melvin K, Berry P, Shintani A, Eden SK, Terrell MK, Boswell T, Wolfram K, Sopfe J, Barr FE, Pandharipande PP, Ely EW. Diagnosing delirium in critically ill children: Validity and reliability of the Pediatric Confusion Assessment Method for the Intensive Care Unit (pCAM-ICU). Crit Care Med. 2011; 39:150–157. [abstract] (File Cabinet)

November 2010

  • Muñoz-Bonet JI, Flor-Macián EM, Brines J, RosellĂł-Millet PM, Cruz Llopis M, LĂłpez-Prats JL, Castillo S. Predictive factors for the outcome of noninvasive ventilation in pediatric acute respiratory failure. Pediatr Crit Care Med. 2010 Nov;11(6):675-80. [abstract; full-text (pdf: 434K)] (File Cabinet, EB Journal Club)
  • Faustino EV, Bogue CW. Relationship between hypoglycemia and mortality in critically ill children. Pediatr Crit Care Med. 2010 Nov;11(6):690-8. [abstract] (File Cabinet)
  • Rake AJ, Srinivasan V, Nadkarni V, Kaptan R, Newth CJ. Glucose variability and survival in critically ill children: Allostasis or harm? Pediatr Crit Care Med. 2010 Nov;11(6):707-712. [abstract] (File Cabinet)
  • Bembea MM, Nadkarni VM, Diener-West M, Venugopal V, Carey SM, Berg RA, Hunt EA; for the American Heart Association National Registry of Cardiopulmonary Resuscitation Investigators. Temperature patterns in the early postresuscitation period after pediatric inhospital cardiac arrest. Pediatr Crit Care Med. 2010 Nov;11(6):723-730. [abstract] (File Cabinet, EB Journal Club)
  • Edwards JD, Kun SS, Keens TG. Outcomes and Causes of Death in Children on Home Mechanical Ventilation via Tracheostomy: An Institutional and Literature Review. J Pediatr. 2010 Dec;157(6):955-959.e2. [abstract] (File Cabinet)

October 2010

  • Lacherade JC, De Jonghe B, Guezennec P, Debbat K, Hayon J, Monsel A, Fangio P, Appere de Vecchi C, Ramaut C, Outin H, Bastuji-Garin S. Intermittent Subglottic Secretion Drainage and Ventilator-associated Pneumonia: A Multicenter Trial. Am J Respir Crit Care Med. 2010 Oct 1;182(7):910-7. [abstract] (File Cabinet, EB Journal Club)
  • Lee KJ, Tieves K, Scanlon MC. Alterations in End-of-Life Support in the Pediatric Intensive Care Unit. Pediatrics. 2010; 126:e859-e864. [abstract; free full-text] (File Cabinet)
  • Frader J, Kodish E, Lantos JD. Symbolic Resuscitation, Medical Futility, and Parental Rights. Pediatrics. 2010; 126:769-772. [citation] (File Cabinet)
  • Rowlands HE, Goldman AP, Harrington K, Karimova A, Brierley J, Cross N, Skellett S, Peters MJ. Impact of Rapid Leukodepletion on the Outcome of Severe Clinical Pertussis in Young Infants. Pediatrics. 2010; 126;816-827. [abstract] (File Cabinet, EB Journal Club)
  • Simbruner G, Mittal RA, Rohlmann F, Muche R; neo.nEURO.network Trial Participants. Systemic Hypothermia After Neonatal Encephalopathy: Outcomes of neo.nEURO.network RCT. Pediatrics. 2010; 126 e771-e778 [abstract; free full-text] (File Cabinet)
  • Shah SS, Hall M, Srivastava R, Subramony A, Levin JE. Intravenous immunoglobulin in children with streptococcal toxic shock syndrome. Clin Infect Dis. 2009 Nov 1;49(9):1369-76. [abstract] (File Cabinet, EB Journal Club)
  • Bobrow BJ, Spaite DW, Berg RA, Stolz U, Sanders AB, Kern KB, Vadeboncoeur TF, Clark LL, Gallagher JV, Stapczynski JS, LoVecchio F, Mullins TJ, Humble WO, Ewy GA. Chest compression-only CPR by lay rescuers and survival from out-of-hospital cardiac arrest. JAMA. 2010 Oct 6;304(13):1447-54. [abstract] (File Cabinet, EB Journal Club)
  • Zimmerman JJ, Barker RM, Jack R. Initial observations regarding free cortisol quantification logistics among critically ill children. Intensive Care Med. 2010 Nov;36(11):1914-22. [abstract] (File Cabinet)
  • Peeters B, Jansen NJ, Bollen CW, van Vught AJ, van der Heide D, Albers MJ. Off-hours admission and mortality in two pediatric intensive care units without 24-h in-house senior staff attendance. Intensive Care Med. 2010 Nov;36(11):1923-7. [abstract] (File Cabinet, EB Journal Club)
  • Kleinman ME, Chameides L, Schexnayder SM, Samson RA, Hazinski MF, Atkins DL, Berg MD, de Caen AR, Fink EL, Freid EB, Hickey RW, Marino BS, Nadkarni VM, Proctor LT, Qureshi FA, Sartorelli K, Topjian A, van der Jagt EW, Zaritsky AL. Part 14: pediatric advanced life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2010;122(suppl 3):S876–S908. [full-text pdf 3.7 MB] (The supplement in Circulation with the complete "2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science" is here...) (File Cabinet)
  • Neily J, Mills PD, Young-Xu Y, Carney BT, West P, Berger DH, Mazzia LM, Paull DE, Bagian JP. Association between implementation of a medical team training program and surgical mortality. JAMA. 2010 Oct 20;304(15):1693-700. [abstract] (File Cabinet)
  • Rouette J, Trottier H, Ducruet T, Beaunoyer M, Lacroix J, Tucci M; Canadian Critical Care Trials Group; PALISI Network. Red blood cell transfusion threshold in postsurgical pediatric intensive care patients: a randomized clinical trial. Ann Surg. 2010 Mar;251(3):421-7. [abstract] (File Cabinet, EB Journal Club)

September 2010

  • Janvier A. I think it is time to stop.Pediatr Crit Care Med. 2010 Sep;11(5):624-5. [citation] (File Cabinet)
  • Agarwal S, Classen D, Larsen G, Tofil NM, Hayes LW, Sullivan JE, Storgion SA, Coopes BJ, Craig V, Jaderlund C, Bisarya H, Parast L, Sharek P. Prevalence of adverse events in pediatric intensive care units in the United States. Pediatr Crit Care Med. 2010 Sep;11(5):568-578. [abstract] (File Cabinet)
  • Nowak JE, Brilli RJ, Lake MR, Sparling KW, Butcher J, Schulte M, Wheeler DS. Reducing catheter-associated bloodstream infections in the pediatric intensive care unit: Business case for quality improvement. Pediatr Crit Care Med. 2010 Sep;11(5):579-587. [abstract] (File Cabinet)
  • Namachivayam P, Shann F, Shekerdemian L, Taylor A, van Sloten I, Delzoppo C, Daffey C, Butt W. Three decades of pediatric intensive care: Who was admitted, what happened in intensive care, and what happened afterward. Pediatr Crit Care Med. 2010 Sep;11(5):549-55. [abstract; full-text (184K)] (File Cabinet)
  • Jouvet P, Hutchison J, Pinto R, Menon K, Rodin R, Choong K, Kesselman M, Veroukis S, AndrĂ© Dugas M, Santschi M, Guerguerian AM, Withington D, Alsaati B, Joffe AR, Drews T, Skippen P, Rolland E, Kumar A, Fowler R; for the Canadian Critical Care Trials Group H1N1 Collaborative. Critical illness in children with influenza A/pH1N1 2009 infection in Canada. Pediatr Crit Care Med. 2010 Sep;11(5):603-609. [abstract] (File Cabinet)
  • Carcillo JA, Orr R, Bell M, Joffe A, Maffei FA, Sullivan J, Han YY, Thomas J. A call for full public disclosure and moratorium on donation after cardiac death in children. Pediatr Crit Care Med. 2010 Sep;11(5):641-3. [citation]. With author replies: Webster PA. Pediatr Crit Care Med. 2010 Sep;11(5):643-4. [citation] and Mathur M, Abd-Allah S, Orr RD. Pediatr Crit Care Med. 2010 Sep;11(5):644-5. [citation] (File Cabinet)
  • Jansen TC, van Bommel J, Schoonderbeek J, Sleeswijk Visser SJ, van der Klooster JM, Lima AP, Willemsen SP, Bakker J; for the LACTATE Study Group. Early Lactate-Guided Therapy in ICU Patients: A Multicenter, Open-Label, Randomized, Controlled Trial. Am J Respir Crit Care Med. 2010; 182:752-761 [abstract] (File Cabinet, EB Journal Club)
  • Sevransky JE, Checkley W, Martin GS. Critical care trial design and interpretation: a primer. Crit Care Med. 2010 Sep;38(9):1882-9. [abstract] (File Cabinet)
  • WFPICCS Newsletter, September 15, 2010, volume 3 no. 2. [pdf; 346K] (Organizations)
  • Papazian L, Forel JM, Gacouin A, Penot-Ragon C, Perrin G, Loundou A, Jaber S, Arnal JM, Perez D, Seghboyan JM, Constantin JM, Courant P, Lefrant JY, GuĂ©rin C, Prat G, Morange S, Roch A. Neuromuscular Blockers in Early Acute Respiratory Distress Syndrome. N Engl J Med. 2010 Sep 16;363(12):1107-1116. [abstract] (File Cabinet, EB Journal Club)
  • Squadrone V, Massaia M, Bruno B, Marmont F, Falda M, Bagna C, Bertone S, Filippini C, Slutsky AS, Vitolo U, Boccadoro M, Ranieri VM. Early CPAP prevents evolution of acute lung injury in patients with hematologic malignancy. Intensive Care Med. 2010 Oct;36(10):1666-74. [abstract] (File Cabinet, EB Journal Club)

August 2010

  • Jeschke MG, Kulp GA, Kraft R, Finnerty CC, Mlcak R, Lee JO, Herndon DN. Intensive Insulin Therapy in Severely Burned Pediatric Patients: A Prospective Randomized Trial. Am J Respir Crit Care Med. 2010; 182 351-359. [abstract] (File Cabinet, EB Journal Club)
  • A supplement in the April issue of Intensive Care Medicine on ICU preparations for epidemic or mass disaster. Selected chapters include: (File Cabinet)
    • Sprung CL, Cohen R, Adini B; European Society of Intensive Care Medicine's Task Force for intensive care unit triage during an influenza epidemic or mass disaster. Chapter 1. Introduction. Recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza epidemic or mass disaster. Intensive Care Med. 2010 Apr;36 Suppl 1:S4-10. [abstract]
    • Hick JL, Christian MD, Sprung CL; European Society of Intensive Care Medicine's Task Force for intensive care unit triage during an influenza epidemic or mass disaster. Chapter 2. Surge capacity and infrastructure considerations for mass critical care. Recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza epidemic or mass disaster. Intensive Care Med. 2010 Apr;36 Suppl 1:S11-20. [abstract]
    • Christian MD, Joynt GM, Hick JL, Colvin J, Danis M, Sprung CL; European Society of Intensive Care Medicine's Task Force for intensive care unit triage during an influenza epidemic or mass disaster. Chapter 7. Critical care triage. Recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza epidemic or mass disaster. Intensive Care Med. 2010 Apr;36 Suppl 1:S55-64.[abstract]
    • Zimmerman JL, Sprung CL; European Society of Intensive Care Medicine's Task Force for intensive care unit triage during an influenza epidemic or mass disaster. Chapter 8. Medical procedures. Recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza epidemic or mass disaster. Intensive Care Med. 2010 Apr;36 Suppl 1:S65-9. [abstract]
  • Point/counterpoint on donation after cardiac death in the July 2010 issue of Chest: (File Cabinet)
    • Bernat JL. Point: are donors after circulatory death really dead, and does it matter? Yes and yes. Chest. 2010 Jul;138(1):13-6. [citation]
    • Truog RD, Miller FG. Counterpoint: are donors after circulatory death really dead, and does it matter? No and not really. Chest. 2010 Jul;138(1):16-8. [citation]
  • Cavallazzi R, Marik PE, Hirani A, Pachinburavan M, Vasu TS, Leiby BE. Association between time of admission to the ICU and mortality: a systematic review and metaanalysis. Chest. 2010 Jul;138(1):68-75 [abstract] (File Cabinet, EB Journal Club)
  • Davison DL, Chawla LS, Selassie L, Jones EM, McHone KC, Vota AR, Junker C, Sateri S, Seneff MG. Femoral-based central venous oxygen saturation is not a reliable substitute for subclavian/internal jugular-based central venous oxygen saturation in patients who are critically ill. Chest. 2010 Jul;138(1):76-83. [abstract] (File Cabinet, EB Journal Club)
  • Rea TD, Fahrenbruch C, Culley L, Donohoe RT, Hambly C, Innes J, Bloomingdale M, Subido C, Romines S, Eisenberg MS. CPR with Chest Compression Alone or with Rescue Breathing N Engl J Med 2010; 363:423-433 [abstract] (File Cabinet, EB Journal Club)
  • Svensson L, Bohm K, Castren M, Pettersson H, Engerstrom L, Herlitz J, Rosenqvist M. Compression-Only CPR or Standard CPR in Out-of-Hospital Cardiac Arrest. N Engl J Med 2010; 363:434-442. [abstract] (File Cabinet, EB Journal Club)
  • Namachivayam P, Theilen U, Butt WW, Cooper SM, Penny DJ, Shekerdemian LS. Sildenafil prevents rebound pulmonary hypertension after withdrawal of nitric oxide in children. Am J Respir Crit Care Med. 2006 Nov 1;174(9):1042-7 [abstract] (File Cabinet, EB Journal Club)

July 2010

  • Tibballs J. A critique of the apneic oxygenation test for the diagnosis of "brain death". Pediatr Crit Care Med. 2010 Jul;11(4):475-8. [abstract]
  • Eulmesekian PG, PĂ©rez A, Minces PG, Bohn D. Hospital-acquired hyponatremia in postoperative pediatric patients: prospective observational study. Pediatr Crit Care Med. 2010 Jul;11(4):479-83. [abstract] (File Cabinet, EB Journal Club)
  • Schroeder AR, Axelrod DM, Silverman NH, Rubesova E, Merkel E, Roth SJ. A continuous heparin infusion does not prevent catheter-related thrombosis in infants after cardiac surgery. Pediatr Crit Care Med. 2010 Jul;11(4):489-95. [abstract] (File Cabinet, EB Journal Club)
  • White M, Barron J, Gornbein J, Lin JA. Are red blood cell transfusions associated with nosocomial infections in pediatric intensive care units? Pediatr Crit Care Med. 2010 Jul;11(4):464-8. [abstract] [full-text; (pdf 140K) ](File Cabinet, EB Journal Club)
  • Launay E, Gras-Le Guen C, Martinot A, Assathiany R, Blanchais T, Mourdi N, Aouba A, Bouvier-Colle MH, RozĂ© JC, Chalumeau M. Suboptimal care in the initial management of children who died from severe bacterial infection: a population-based confidential inquiry. Pediatr Crit Care Med. 2010 Jul;11(4):469-74. [abstract] (File Cabinet)
  • The World Federation of Pediatric Intensive and Critical Care Societies: a Global Pediatric Sepsis Initiative at http://www.pediatricsepsis.org (Organizations)
  • The AAP Section on Critical Care's Summer 2010 newsletter is here... (pdf; 780K) (Organizations)
  • Menon K, Ward RE, Lawson ML, Gaboury I, Hutchison JS, HĂ©bert PC, Canadian Critical Care Trials Group. A Prospective Multi-Center Study of Adrenal Function in Critically Ill Children. Am J Respir Crit Care Med. 2010; 182:246-251. [abstract] (File Cabinet, EB Journal Club)
  • Puri V, Epstein D, Raithel SC, Gandhi SK, Sweet SC, Faro A, Huddleston CB. Extracorporeal membrane oxygenation in pediatric lung transplantation. J Thorac Cardiovasc Surg. 2010 Aug;140(2):427-32. [abstract] (File Cabinet, EB Journal Club)

June 2010

  • Ohye RG, Sleeper LA, Mahony L, Newburger JW, Pearson GD, Lu M, Goldberg CS, Tabbutt S, Frommelt PC, Ghanayem NS, Laussen PC, Rhodes JF, Lewis AB, Mital S, Ravishankar C, Williams IA, Dunbar-Masterson C, Atz AM, Colan S, Minich LL, Pizarro C, Kanter KR, Jaggers J, Jacobs JP, Krawczeski CD, Pike N, McCrindle BW, Virzi L, Gaynor JW; the Pediatric Heart Network Investigators. Comparison of Shunt Types in the Norwood Procedure for Single-Ventricle Lesions. N Engl J Med. 2010 May 27;362(21):1980-1992. [abstract] (File Cabinet, EB Journal Club)
  • Two interesting point-counterpoint editorials regarding 24/7 in-house intensivist staffing: Burnham El, Mass M, Geraci MW. The Case for 24/7 In-House Intensivist Coverage Am. J. Respir. Crit. Care Med. 2010;181 1159-1160 [full-text], and Kahn JM, Hall JB. More Doctors to the Rescue in the Intensive Care Unit: A Cautionary Note. Am. J. Respir. Crit. Care Med. 2010;181 1160-1161 [full-text]
  • Esan A, Hess DR, Raoof S, George L, Sessler CN. Severe hypoxemic respiratory failure: part 1--ventilatory strategies. Chest. 2010 May;137(5):1203-16. [abstract] (File Cabinet)
  • Cornell TT, Wynn J, Shanley TP, Wheeler DS, Wong HR. Mechanisms and regulation of the gene-expression response to sepsis. Pediatrics. 2010 Jun;125(6):1248-58. [abstract] (File Cabinet)
  • Westermaier T, Stetter C, Vince GH, Pham M, Tejon JP, Eriskat J, Kunze E, Matthies C, Ernestus RI, Solymosi L, Roosen K. Prophylactic intravenous magnesium sulfate for treatment of aneurysmal subarachnoid hemorrhage: a randomized, placebo-controlled, clinical study. Crit Care Med. 2010 May;38(5):1284-90. [abstract] (File Cabinet, EB Journal Club)
  • Kilgannon JH, Jones AE, Shapiro NI, Angelos MG, Milcarek B, Hunter K, Parrillo JE, Trzeciak S; Emergency Medicine Shock Research Network (EMShockNet) Investigators. Association between arterial hyperoxia following resuscitation from cardiac arrest and in-hospital mortality. JAMA. 2010 Jun 2;303(21):2165-71. [abstract] (File Cabinet, EB Journal Club)
  • WFPICCS (World Federation of Pediatric Intensive and Critical Care Societies) Newsletter, June 2010 is here... (pdf; 312K) (Organizations)
  • Typpo KV, Petersen NJ, Petersen LA, Mariscalco MM. Children with Chronic Illness Return to Their Baseline Functional Status after Organ Dysfunction on the First Day of Admission in the Pediatric Intensive Care Unit. J Pediatr. 2010 Jul;157(1):108-113.e1. Epub 2010 Mar 10. [abstract] (File Cabinet, EB Journal Club)

May 2010

  • Terragni PP, Antonelli M, Fumagalli R, et al. Early vs Late Tracheotomy for Prevention of Pneumonia in Mechanically Ventilated Adult ICU Patients. A Randomized Controlled Trial. JAMA. 2010;303(15):1483-1489 [abstract] (File Cabinet, EB Journal Club)
  • Wynn J, Cornell TT, Wong HR, Shanley TP, Wheeler DS. The Host Response to Sepsis and Developmental Impact. Pediatrics. 2010; 125 1031-1041 [abstract] (File Cabinet)
  • Anand KJ, Willson DF, Berger J, Harrison R, Meert KL, Zimmerman J, Carcillo J, Newth CJ, Prodhan P, Dean JM, Nicholson C; for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network. Tolerance and Withdrawal From Prolonged Opioid Use in Critically Ill Children. Pediatrics. 2010; 125 e1208-e1225 [abstract] (File Cabinet)
  • Afessa B, Shorr AF, Anzueto AR, Craven DE, Schinner R, Kollef MH. Association Between a Silver-Coated Endotracheal Tube and Reduced Mortality in Patients With Ventilator-Associated Pneumonia. Chest. 2009; 137;1015-1021 [abstract] (File Cabinet, EB Journal Club)
  • Bach JR, Gonçalves MR, Hamdani I, Winck JC. Extubation of Patients with Neuromuscular Weakness: A New Management Paradigm. Chest. 2010; 137:1033-1039 [abstract] (File Cabinet)
  • Raymond TT, Cunnyngham CB, Thompson MT, Thomas JA, Dalton HJ, Nadkarni VM; for the American Heart Association National Registry of CPR Investigators. Outcomes among neonates, infants, and children after extracorporeal cardiopulmonary resuscitation for refractory in-hospital pediatric cardiac arrest: A report from the National Registry of CardioPulmonary Resuscitation. Pediatr Crit Care Med 2010; 11:362–371 [abstract; full-text (pdf:668K)] (File Cabinet, EB Journal Club)
  • del Castillo SL, McCulley ME, Khemani RG, Jeffries HE, Thomas DW, Peregrine J, Wells WJ, Starnes VA, Moromisato DY. Reducing the incidence of necrotizing enterocolitis in neonates with hypoplastic left heart syndrome with the introduction of an enteral feed protocol* Pediatr Crit Care Med 2010; 11(3):373-377. [abstract] (File Cabinet, EB Journal Club)
  • Spragg RG, Bernard GR, Checkley W, Curtis JR, Gajic O, Guyatt G, Hall J, Israel E, Jain M, Needham DM, Randolph AG, Rubenfeld GD, Schoenfeld D, Thompson BT, Ware LB, Young D, Harabin AL. Beyond mortality: future clinical research in acute lung injury. Am J Respir Crit Care Med. 2010 May 15;181(10):1121-7 [abstract] (File Cabinet)
  • Brochard L, Abroug F, Brenner M, Broccard AF, Danner RL, Ferrer M, Laghi F, Magder S, Papazian L, Pelosi P, Polderman KH; ATS/ERS/ESICM/SCCM/SRLF Ad Hoc Committee on Acute Renal Failure. An Official ATS/ERS/ESICM/SCCM/SRLF Statement: Prevention and Management of Acute Renal Failure in the ICU Patient: an international consensus conference in intensive care medicine. Am J Respir Crit Care Med. 2010 May 15;181(10):1128-55. [abstract] (File Cabinet)
  • Gauvin F, Spinella PC, Lacroix J, Choker G, Ducruet T, Karam O, HĂ©bert PC, Hutchison JS, Hume HA, Tucci M. Association between length of storage of transfused red blood cells and multiple organ dysfunction syndrome in pediatric intensive care patients. Transfusion. 2010 Apr 30. [Epub ahead of print][abstract] (File Cabinet, EB Journal Club)

April 2010

  • Hartzband P, Groopman J. Untangling the Web — Patients, Doctors, and the Internet. New Engl J Med 2010; 362:1063-1066 [full-text] (File Cabinet)
  • Gaieski DF, Mikkelsen ME, Band RA, Pines JM, Massone R, Furia FF, Shofer FS, Goyal M. Impact of time to antibiotics on survival in patients with severe sepsis or septic shock in whom early goal-directed therapy was initiated in the emergency department. Crit Care Med. 2010 Apr;38(4):1045-53. [abstract] (File Cabinet, EB Journal Club)
  • Committee on Hospital Care, Section on Surgery, and Section on Critical Care. Policy statement--pediatric organ donation and transplantation. Pediatrics. 2010 Apr;125(4):822-8. [abstract; full-text (pdf 270K)] (File Cabinet)
  • Akre M, Finkelstein M, Erickson M, Liu M, Vanderbilt L, Billman G. Sensitivity of the pediatric early warning score to identify patient deterioration. Pediatrics. 2010 Apr;125(4):e763-9. [abstract; full-text] (File Cabinet, EB Journal Club)
  • Miller RR 3rd, Markewitz BA, Rolfs RT, Brown SM, Dascomb KK, Grissom CK, Friedrichs MD, Mayer J, Hirshberg EL, Conklin J, Paine R 3rd, Dean NC. Clinical findings and demographic factors associated with intensive care unit admission in Utah due to 2009 novel influenza A (H1N1) infection. Chest 2010;137;752-758 [abstract] (File Cabinet)
  • Jung YJ, Koh Y, Hong SB, Chung JW, Ho Choi S, Kim NJ, Kim MN, Choi IS, Han SY, Kim WD, Yun SC, Lim CM. Effect of vancomycin plus rifampicin in the treatment of nosocomial methicillin-resistant Staphylococcus aureus pneumonia. Crit Care Med. 2010 Jan;38(1):175-80. [abstract] (File Cabinet, EB Journal Club)
  • Hornby K, Hornby L, Shemie SD. A systematic review of autoresuscitation after cardiac arrest. Crit Care Med. 2010; 38(5):1246-1253 [abstract] (File Cabinet)
  • Curley G, Kavanagh BP, Laffey JG. Hypocapnia and the injured brain: More harm than benefit. Crit Care Med. 2010; 38(5):1348-1359 [abstract] (File Cabinet)
  • Wert RV, Friedrich JO, Scales DC, Wald R, Adhikari NK; for the University of Toronto Acute Kidney Injury Research Group. High-dose renal replacement therapy for acute kidney injury: Systematic review and meta-analysis. Crit Care Med. 2010; 38(5):1360-1369 [abstract] (File Cabinet, EB Journal Club)
  • Silvestri L, van Saene HK, Zandstra DF, Marshall JC, Gregori D, Gullo A. Impact of selective decontamination of the digestive tract on multiple organ dysfunction syndrome: Systematic review of randomized controlled trials. Crit Care Med. 2010; 38(5):1370-1376 [abstract] (File Cabinet, EB Journal Club)
  • Ortega R, Song M, Hansen CJ, Barash P. Ultrasound-Guided Internal Jugular Vein Cannulation. New Engl J Med 2010; 362:e57. [video] (File Cabinet)

March 2010

  • De Backer D, Biston P, Devriendt J, Madl C, Chochrad D, Aldecoa C, Brasseur A, Defrance P, Gottignies P, Vincent JL; SOAP II Investigators. Comparison of dopamine and norepinephrine in the treatment of shock. N Engl J Med. 2010 Mar 4;362(9):779-89. [abstract] (File Cabinet, EB Journal Club)
  • Briel M, Meade M, Mercat A, Brower RG, Talmor D, Walter SD, Slutsky AS, Pullenayegum E, Zhou Q, Cook D, Brochard L, Richard JC, Lamontagne F, Bhatnagar N, Stewart TE, Guyatt G. Higher vs lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: systematic review and meta-analysis. JAMA. 2010 Mar 3;303(9):865-73. [abstract] (File Cabinet, EB Journal Club)
  • Jones AE, Shapiro NI, Trzeciak S, Arnold RC, Claremont HA, Kline JA; Emergency Medicine Shock Research Network (EMShockNet) Investigators. Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial. JAMA. 2010 Feb 24;303(8):739-46. [abstract] (File Cabinet, EB Journal Club)
  • Lung Opening and Closing During Ventilation of Acute Respiratory Distress Syndrome. Caironi P, Cressoni M, Chiumello D, Ranieri M, Quintel M, Russo SG, Cornejo R, Bugedo G, Carlesso E, Russo R, Caspani L, Gattinoni L. Am J Respir Crit Care Med 2010; 181:578-586 [abstract] (File Cabinet)
  • Gaies MG, Gurney JG, Yen AH, Napoli ML, Gajarski RJ, Ohye RG, Charpie JR, Hirsch JC. Vasoactive-inotropic score as a predictor of morbidity and mortality in infants after cardiopulmonary bypass* Pediatr Crit Care Med 2010; 11:234–238. [abstract] (File Cabinet, EB Journal Club)
  • Sorce L, Simone S, Madden M. Educational preparation and post graduate training curriculum for pediatric critical care nurse practitioners* Pediatr Crit Care Med 11:205–212 [abstract; full-text (pdf 197K)] (Advanced Practice Nursing)
  • Sachdev A, Chugh K, Sethi M, Gupta D, Wattal C, Menon G. Diagnosis of ventilator-associated pneumonia in children in resource-limited setting: A comparative study of bronchoscopic and nonbronchoscopic methods* Pediatr Crit Care Med. 2010; 11: 258-266 [abstract] (File Cabinet, EB Journal Club)
  • The 2010 Winter Newsletter from CoPS (Council on Pediatric Subspecialities) is now available here... (pdf; 90K) (Organizations)
  • Srinivasan V, Nadkarni VM, Helfaer MA, Carey SM, Berg RA; American Heart Association National Registry of Cardiopulmonary Resuscitation Investigators. Childhood obesity and survival after in-hospital pediatric cardiopulmonary resuscitation. Pediatrics. 2010 Mar;125(3):e481-8. Epub 2010 Feb 22. [abstract] (File Cabinet, EB Journal Club)
  • McKiernan C, Chua LC, Visintainer PF, Allen H. High Flow Nasal Cannulae Therapy in Infants with Bronchiolitis. J Pediatr. 2010 Apr;156(4):634-638 [abstract] (File Cabinet, EB Journal Club)
  • "The EMSC National Resource Center has developed an online interactive map designed to provide health care professionals interested in volunteering a resource to identify disaster volunteer agencies in their state." The map is here.... (Organizations)

February 2010

  • Santamaria J, Tobin A, Holmes J. Changing cardiac arrest and hospital mortality rates through a medical emergency team takes time and constant review. Crit Care Med. 2010 Feb;38(2):445-50. [abstract] (File Cabinet)
  • Willems A, Harrington K, Lacroix J, Biarent D, Joffe AR, Wensley D, Ducruet T, HĂ©bert PC, Tucci M; TRIPICU investigators; Canadian Critical Care Trials Group; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Comparison of two red-cell transfusion strategies after pediatric cardiac surgery: a subgroup analysis. Crit Care Med. 2010 Feb;38(2):649-56. [abstract] (File Cabinet, EB Journal Club)
  • WFPICCS Newsletter, February 1, 2010, volume 3 no. 1. [pdf; 238K] (Organizations)
  • COIITSS Study Investigators, Annane D, Cariou A, Maxime V, Azoulay E, D'honneur G, Timsit JF, Cohen Y, Wolf M, Fartoukh M, Adrie C, SantrĂ© C, Bollaert PE, Mathonet A, Amathieu R, Tabah A, Clec'h C, Mayaud J, Lejeune J, Chevret S. Corticosteroid treatment and intensive insulin therapy for septic shock in adults: a randomized controlled trial. JAMA. 2010 Jan 27;303(4):341-8. [abstract] (File Cabinet, EB Journal Club)
  • Angus DC, Mira JP, Vincent JL. Improving clinical trials in the critically ill. Crit Care Med. 2010 Feb;38(2):527-32. [abstract] (File Cabinet)
  • Miller MR, Griswold M, Harris JM 2nd, Yenokyan G, Huskins WC, Moss M, Rice TB, Ridling D, Campbell D, Margolis P, Muething S, Brilli RJ. Decreasing PICU Catheter-Associated Bloodstream Infections: NACHRI's Quality Transformation Efforts. Pediatrics. 2010; 125 206-213 [abstract] (File Cabinet, EB Journal Club)
  • Truog RD. Is It Always Wrong to Perform Futile CPR? N Engl J Med. 2010 Feb 11;362(6):477-9. [citation] (File Cabinet)
  • Schneider J, Khemani R, Grushkin C, Bart R. Serum creatinine as stratified in the RIFLE score for acute kidney injury is associated with mortality and length of stay for children in the pediatric intensive care unit. Crit Care Med. 2010 Mar;38(3):933-9.[abstract] (File Cabinet, EB Journal Club)

January 2010

  • Dennen P, Douglas IS, Anderson R. Acute kidney injury in the intensive care unit: an update and primer for the intensivist. Crit Care Med. 2010 Jan;38(1):261-75. [abstract] (File Cabinet)
  • Frankenfield DC, Alam S, Bekteshi E, Vender RL. Predicting dead space ventilation in critically ill patients using clinically available data. Crit Care Med. 2010 Jan;38(1):288-91. [abstract] (File Cabinet)
  • Manrique AM, Arroyo M, Lin Y, El Khoudary SR, Colvin E, Lichtenstein S, Chrysostomou C, Orr R, Jooste E, Davis P, Wearden P, Morell V, Munoz R. Magnesium supplementation during cardiopulmonary bypass to prevent junctional ectopic tachycardia after pediatric cardiac surgery: A randomized controlled study. J Thorac Cardiovasc Surg. 2010;139:162-9 [abstract] (File Cabinet, EB Journal Club)
  • Preissig CM, Rigby MR. Pediatric critical illness hyperglycemia: risk factors associated with development and severity of hyperglycemia in critically ill children. J Pediatr. 2009 Nov;155(5):734-9 [abstract] (File Cabinet)
  • Toussaint S, Gerlach H. Activated protein C for sepsis. N Engl J Med. 2009 Dec 31;361(27):2646-52. [citation] (File Cabinet)
  • Thomas EJ, Lucke JF, Wueste L, Weavind L, Patel B. Association of telemedicine for remote monitoring of intensive care patients with mortality, complications, and length of stay. JAMA. 2009 Dec 23;302(24):2671-8. [abstract] (File Cabinet, EB Journal Club)
  • Willson DF, Dean JM, Meert KL, Newth CJ, Anand KJ, Berger J, Harrison R, Zimmerman J, Carcillo J, Pollack M, Holubkov R, Jenkins TL, Nicholson C; for the Eunice Kennedy Shriver National Institute of Child Health, and Human Development Collaborative Pediatric Critical Care Research Network. Collaborative Pediatric Critical Care Research Network: Looking back and moving forward. Pediatr Crit Care Med 2010; 11(1):1-6. [abstract] (File Cabinet, Research)
  • Breatnach C, Conlon NP, Stack M, Healy M, O'Hare BP. A prospective crossover comparison of neurally adjusted ventilatory assist and pressure-support ventilation in a pediatric and neonatal intensive care unit population* Pediatr Crit Care Med 2010; 11(1):7-11 [abstract; full-text (pdf; 262K)] (File Cabinet, EB Journal Club)
  • Fink EL, Clark RS, Kochanek PM, Bell MJ, Watson RS. A tertiary care center's experience with therapeutic hypothermia after pediatric cardiac arrest. Pediatr Crit Care Med. 2010; 11(1):66-74 [abstract] (File Cabinet, EB Journal Club)
  • Reveiz L, Guerrero-Lozano R, Camacho A, Yara L, Mosquera PA. Stress ulcer, gastritis, and gastrointestinal bleeding prophylaxis in critically ill pediatric patients: A systematic review* Pediatr Crit Care Med. 2010; 11(1):124-132 [abstract] (File Cabinet, EB Journal Club)
  • Thomas NJ, Shaffer ML, Willson DF, Shih MC, Curley MA. Defining acute lung disease in children with the oxygenation saturation index. Pediatr Crit Care Med. 2010; 11(1):12-17 [abstract] (File Cabinet)
  • Levy MM, Dellinger RP, Townsend SR, Linde-Zwirble WT, Marshall JC, Bion J, Schorr C, Artigas A, Ramsay G, Beale R, Parker MM, Gerlach H, Reinhart K, Silva E, Harvey M, Regan S, Angus DC. The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis. Crit Care Med. 2010; 38:367-374. [abstract] (File Cabinet)
  • Rajagopal SK, Almond CS, Laussen PC, Rycus PT, Wypij D, Thiagarajan RR. Extracorporeal membrane oxygenation for the support of infants, children, and young adults with acute myocarditis: a review of the Extracorporeal Life Support Organization registry. Crit Care Med. 2010 Feb;38(2):382-7. [abstract] (File Cabinet, EB Journal Club)

December 2009

  • Del Castillo SL, McCulley ME, Khemani RG, Jeffries HE, Thomas DW, Peregrine J, Wells WJ, Starnes VA, Moromisato DY. Reducing the incidence of necrotizing enterocolitis in neonates with hypoplastic left heart syndrome with the introduction of an enteral feed protocol* Pediatr Crit Care Med. 2009 Oct 20. [Epub ahead of print] [abstract] (File Cabinet)
  • Cobb JP, Ognibene FP, Ingbar DH, Mann HJ, Hoyt DB, Angus DC, Thomas AV Jr, Danner RL, Suffredini AF. Forging a critical alliance: Addressing the research needs of the United States critical illness and injury community. Crit Care Med. 2009 Dec;37(12):3158-3160. [abstract] (File Cabinet)
  • Donoghue A, Berg RA, Hazinski MF, Praestgaard AH, Roberts K, Nadkarni VM; for the American Heart Association National Registry of CPR Investigators. Cardiopulmonary Resuscitation for Bradycardia With Poor Perfusion Versus Pulseless Cardiac Arrest. Pediatrics. 2009; 124;1541-1548 [abstract] (File Cabinet)
  • O'Brien SM, Clarke DR, Jacobs JP, Jacobs ML, Lacour-Gayet FG, Pizarro C, Welke KF, Maruszewski B, Tobota Z, Miller WJ, Hamilton L, Peterson ED, Mavroudis C, Edwards FH. An empirically based tool for analyzing mortality associated with congenital heart surgery. J Thorac Cardiovasc Surg. 2009 Nov;138(5):1139-53. [abstract] (File Cabinet, EB Journal Club)
  • Afessa B, Gajic O, Morales IJ, Keegan MT, Peters SG, Hubmayr RD. Association between ICU admission during morning rounds and mortality. Chest. 2009 Dec;136(6):1489-95 [abstract] (File Cabinet, EB Journal Club)
  • Sanghavi D. "When Does Death Start" NY Times, December 20, 2009. [full-text] Well written coverage of donation after cardiac death in children. (File Cabinet)
  • WFPICCS Newsletter, December 25, 2009, volume 1 no. 4. [pdf; 176K] (Organizations)
  • Libster R, Bugna J, Coviello S, et al. Pediatric Hospitalizations Associated with 2009 Pandemic Influenza A (H1N1) in Argentina. N Engl J Med. 2009 Dec 23. [Epub ahead of print] [full-text] (File Cabinet)

November 2009

  • Harikumar G, Egberongbe Y, Nadel S, Wheatley E, Moxham J, Greenough A, Rafferty GF. Tension Time Index as a Predictor of Extubation Outcome in Ventilated Children. Am J Respir Crit Care Med. 2009; 180: 982-988. [abstract] (File Cabinet, EB Journal Club)
  • Kesecioglu J, Beale R, Stewart TE, Findlay GP, Rouby JJ, Holzapfel L, Bruins P, Steenken EJ, Jeppesen OK, Lachmann B. Exogenous Natural Surfactant for Treatment of Acute Lung Injury and the Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2009; 180: 989-994. [abstract] (File Cabinet, EB Journal Club)
  • Bronner MB, Knoester H, Sol JJ, Bos AP, Heymans HS, Grootenhuis MA. An explorative study on quality of life and psychological and cognitive function in pediatric survivors of septic shock. Pediatr Crit Care Med. 2009 Nov;10(6):636-42. [abstract] [full-text;188K] (File Cabinet)
  • Michelson KN, Koogler T, Sullivan C, Ortega Mdel P, Hall E, Frader J. Parental views on withdrawing life-sustaining therapies in critically ill children. Arch Pediatr Adolesc Med. 2009 Nov;163(11):986-92. [abstract] (File Cabinet)
  • Ferrer R, Artigas A, Suarez D, Palencia E, Levy MM, Arenzana A, PĂ©rez XL, Sirvent JM; Edusepsis Study Group. Effectiveness of treatments for severe sepsis: a prospective, multicenter, observational study. Am J Respir Crit Care Med. 2009 Nov 1;180(9):861-6. [abstract] (File Cabinet)
  • Taccone P, Pesenti A, Latini R, Polli F, Vagginelli F, Mietto C, Caspani L, Raimondi F, Bordone G, Iapichino G, Mancebo J, GuĂ©rin C, Ayzac L, Blanch L, Fumagalli R, Tognoni G, Gattinoni L; for the Prone-Supine II Study Group. Prone Positioning in Patients With Moderate and Severe Acute Respiratory Distress Syndrome: A Randomized Controlled Trial. JAMA. 2009 Nov 11;302(18):1977-1984. [abstract] (File Cabinet, EB Journal Club)
  • Ventre KM, Collingridge DS, DeCarlo D, Schwid HA. Performance of a consensus scoring algorithm for assessing pediatric advanced life support competency using a computer screen-based simulator. Pediatr Crit Care Med. 2009 Nov;10(6):623-35. [abstract] (File Cabinet)
  • RENAL Replacement Therapy Study Investigators, Bellomo R, Cass A, Cole L, Finfer S, Gallagher M, Lo S, McArthur C, McGuinness S, Myburgh J, Norton R, Scheinkestel C, Su S. Intensity of continuous renal-replacement therapy in critically ill patients. N Engl J Med. 2009 Oct 22;361(17):1627-38. [abstract] (File Cabinet, EB Journal Club)
  • Iyer VN, Hoel R, Rabinstein AA. Propofol infusion syndrome in patients with refractory status epilepticus: An 11-year clinical experience. Crit Care Med. 2009 Dec;37(12):3024-3030. [abstract] (File Cabinet)
  • Campello G, Granja C, Carvalho F, Dias C, Azevedo LF, Costa-Pereira A. Immediate and long-term impact of medical emergency teams on cardiac arrest prevalence and mortality: A plea for periodic basic life-support training programs. Crit Care Med. 2009 Dec;37(12):3054-3061. [abstract] (File Cabinet)

October 2009

  • Jain S, Kamimoto L, Bramley AM, Schmitz AM, Benoit SR, Louie J, Sugerman DE, Druckenmiller JK, Ritger KA, Chugh R, Jasuja S, Deutscher M, Chen S, Walker JD, Duchin JS, Lett S, Soliva S, Wells EV, Swerdlow D, Uyeki TM, Fiore AE, Olsen SJ, Fry AM, Bridges CB, Finelli L; the 2009 Pandemic Influenza A (H1N1) Virus Hospitalizations Investigation Team. Hospitalized Patients with 2009 H1N1 Influenza in the United States, April-June 2009. N Engl J Med. 2009 Oct 8. [Epub ahead of print] [abstract] (File Cabinet)
  • Critical Care Services and 2009 H1N1 Influenza in Australia and New Zealand. The ANZIC Influenza Investigators. N Engl J Med. 2009 Oct 8. [Epub ahead of print] [abstract] (File Cabinet)
  • DomĂ­nguez-Cherit G, Lapinsky SE, Macias AE, Pinto R, Espinosa-Perez L, de la Torre A, Poblano-Morales M, Baltazar-Torres JA, Bautista E, Martinez A, Martinez MA, Rivero E, Valdez R, Ruiz-Palacios G, Hernández M, Stewart TE, Fowler RA. Critically Ill Patients With 2009 Influenza A(H1N1) in Mexico. JAMA. 2009 Oct 12. [Epub ahead of print] [abstract] (File Cabinet)
  • Kumar A, Zarychanski R, Pinto R, Cook DJ, Marshall J, Lacroix J, Stelfox T, Bagshaw S, Choong K, Lamontagne F, Turgeon AF, Lapinsky S, Ahern SP, Smith O, Siddiqui F, Jouvet P, Khwaja K, McIntyre L, Menon K, Hutchison J, Hornstein D, Joffe A, Lauzier F, Singh J, Karachi T, Wiebe K, Olafson K, Ramsey C, Sharma S, Dodek P, Meade M, Hall R, Fowler R; for the Canadian Critical Care Trials Group H1N1 Collaborative. Critically Ill Patients With 2009 Influenza A(H1N1) Infection in Canada. JAMA. 2009 Oct 12. [Epub ahead of print] [abstract] (File Cabinet)
  • The Australia and New Zealand Extracorporeal Membrane Oxygenation (ANZ ECMO) Influenza Investigators. Extracorporeal Membrane Oxygenation for 2009 Influenza A(H1N1) Acute Respiratory Distress Syndrome. JAMA. 2009 Oct 12. [Epub ahead of print] [abstract] (File Cabinet)
  • Aronson PL, Yau J, Helfaer MA, Morrison W. Impact of family presence during pediatric intensive care unit rounds on the family and medical team. Pediatrics. 2009 Oct;124(4):1119-25. Epub 2009 Sep 7. [abstract] (File Cabinet)

September 2009

  • Kadmon G, Bron-Harlev E, Nahum E, Schiller O, Haski G, Shonfeld T. Computerized Order Entry With Limited Decision Support to Prevent Prescription Errors in a PICU. Pediatrics. 2009; 124:935-940. [abstract] (File Cabinet)
  • Inoue M, Caldarone CA, Frndova H, Cox PN, Ito S, Taddio A, Guerguerian AM. Safety and efficacy of ketorolac in children after cardiac surgery. Intensive Care Med. 2009 Sep;35(9):1584-92 [abstract] (File Cabinet, EB Journal Club)
  • Vivian L, Marais A, McLaughlin S, Falkenstein S, Argent A. Relationships, trust, decision-making and quality of care in a paediatric intensive care unit. Intensive Care Med. 2009 Sep;35(9):1593-8 [abstract] (File Cabinet)
  • Halpern SD, Randolph AG, Angus DC. No child left behind: Enrolling children and adults simultaneously in critical care randomized trials. Crit Care Med. 2009 Sep;37(9):2638-41. [abstract] (File Cabinet)
  • Meert KL, Donaldson A, Nadkarni V, Tieves KS, Schleien CL, Brilli RJ, Clark RS, Shaffner DH, Levy F, Statler K, Dalton HJ, van der Jagt EW, Hackbarth R, Pretzlaff R, Hernan L, Dean JM, Moler FW; Pediatric Emergency Care Applied Research Network. Multicenter cohort study of in-hospital pediatric cardiac arrest. Pediatr Crit Care Med. 2009 Sep;10(5):544-53. [abstract; Meert-cardiac_arrest.pdf">full-text (pdf:260K)] (File Cabinet)
  • Typpo KV, Petersen NJ, Hallman DM, Markovitz BP, Mariscalco MM. Day 1 multiple organ dysfunction syndrome is associated with poor functional outcome and mortality in the pediatric intensive care unit. Pediatr Crit Care Med. 2009 Sep;10(5):562-70. [abstract] (File Cabinet)
  • Heath B, Salerno R, Hopkins A, Hertzig J, Caputo M. Pediatric critical care telemedicine in rural underserved emergency departments. Pediatr Crit Care Med. 2009 Sep;10(5):588-91. [abstract] (File Cabinet)
  • Kissoon N, Argent A, Devictor D, Madden MA, Singhi S, van der Voort E, Latour JM. World federation of pediatric intensive and critical care societies-its global agenda. Pediatr Crit Care Med. 2009 Sep;10(5):597-600. [abstract] (Organizations)
  • Choong K, Bohn D, Fraser DD, Gaboury I, Hutchison JS, Joffe AR, Litalien C, Menon K, McNamara P, Ward RE. Vasopressin in Pediatric Vasodilatory Shock - A Multi-center Randomized Controlled Trial. Am J Respir Crit Care Med. 2009; 180:632-639 [abstract] (File Cabinet, EB Journal Club)
  • Cameron MA, Schleien CL, Morris MC. Parental Presence on Pediatric Intensive Care Unit Rounds. J Pediatr. 2009;155:522-8. [abstract] (File Cabinet)
  • Peek GJ, Mugford M, Tiruvoipati R, Wilson A, Allen E, Thalanany MM, Hibbert CL, Truesdale A, Clemens F, Cooper N, Firmin RK, Elbourne D; for the CESAR trial collaboration. Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial. Lancet. 2009 Sep 15. [Epub ahead of print] [abstract] (File Cabinet, EB Journal Club)
  • Alberda C, Gramlich L, Jones N, Jeejeebhoy K, Day AG, Dhaliwal R, Heyland DK. The relationship between nutritional intake and clinical outcomes in critically ill patients: results of an international multicenter observational study. Intensive Care Med. 2009 Oct;35(10):1728-37. [abstract] (File Cabinet, EB Journal Club)

August 2009

  • The World Federation of Pediatric Intensive and Critical Care Societies newsletter. July 31, 2009 (vol 2 number 2) is here... (Organizations)
  • The AAP Section on Critical Care Summer 2009 newsletter is here... (pdf; 848K) (Organizations)
  • Young GB. Neurologic Prognosis after Cardiac Arrest. New Engl J Med 2009; 361:605-611. [extract] (File Cabinet)
  • White DB, Evans LR, Bautista CA, Luce JM, Lo B. Are Physicians' Recommendations to Limit Life Support Beneficial or Burdensome? Bringing Empirical Data to the Debate. Am J Respir Crit Care Med. 2009; 180 320-325. [abstract] (File Cabinet)
  • Carcillo JA, Kuch BA, Han YY, Day S, Greenwald BM, McCloskey KA, Pearson-Shaver AL, Orr RA. Mortality and functional morbidity after use of PALS/APLS by community physicians. Pediatrics. 2009 Aug;124(2):500-8. [abstract] (File Cabinet, EB Journal Club)
  • Sutton RM, Niles D, Nysaether J, Abella BS, Arbogast KB, Nishisaki A, Maltese MR, Donoghue A, Bishnoi R, Helfaer MA, Myklebust H, Nadkarni V. Quantitative analysis of CPR quality during in-hospital resuscitation of older children and adolescents. Pediatrics. 2009 Aug;124(2):494-9. [abstract] (File Cabinet)
  • Read Dr. Basnet's Update about opening Nepal's first PICU, as of August 10, 2009 here... (pdf; 40K) (International)

July 2009

  • Pollack MM, Holubkov R, Glass P, Dean JM, Meert KL, Zimmerman J, Anand KJ, Carcillo J, Newth CJ, Harrison R, Willson DF, Nicholson C; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network. Functional status scale: new pediatric outcome measure. Pediatrics. 2009 Jul;124(1):e18-28. [abstract] (File Cabinet)
  • Braga MS, Dominguez TE, Pollock AN, Niles D, Meyer A, Myklebust H, Nysaether J, Nadkarni V. Estimation of optimal CPR chest compression depth in children by using computer tomography. Pediatrics. 2009 Jul;124(1):e69-74. [abstract] (File Cabinet)
  • Zimmerman JJ, Akhtar SR, Caldwell E, Rubenfeld GD. Incidence and outcomes of pediatric acute lung injury. Pediatrics. 2009 Jul;124(1):87-95. [abstract] (File Cabinet)
  • Orr RA, Felmet KA, Han Y, McCloskey KA, Dragotta MA, Bills DM, Kuch BA, Watson RS. Pediatric specialized transport teams are associated with improved outcomes. Pediatrics. 2009 Jul;124(1):40-8. [abstract] (File Cabinet, EB Journal Club)
  • Zebrack M, Dandoy C, Hansen K, Scaife E, Mann NC, Bratton SL. Early resuscitation of children with moderate-to-severe traumatic brain injury. Pediatrics. 2009 Jul;124(1):56-64. [abstract] (File Cabinet, EB Journal Club)
  • Murphy CV, Schramm GE, Doherty JA, Reichley RM, Gajic O, Afessa B, Micek ST, Kollef MH. The Importance of Fluid Management in Acute Lung Injury Secondary to Septic Shock. Chest. 2009; 136:102-109. [abstract] (File Cabinet, EB Journal Club)
  • Barrett CS, Bratton SL, Salvin JW, Laussen PC, Rycus PT, Thiagarajan RR. Neurological injury after extracorporeal membrane oxygenation use to aid pediatric cardiopulmonary resuscitation. Pediatr Crit Care Med. 2009 Jul;10(4):445-451. [abstract] (File Cabinet, EB Journal Club)
  • Braudis NJ, Curley MA, Beaupre K, Thomas KC, Hardiman G, Laussen P, Gauvreau K, Thiagarajan RR. Enteral feeding algorithm for infants with hypoplastic left heart syndrome poststage I palliation. Pediatr Crit Care Med. 2009 Jul;10(4):460-466. [abstract] (File Cabinet, EB Journal Club)
  • Webster PA, Markham L. Pediatric organ donation: A national survey examining consent rates and characteristics of donor hospitals. Pediatr Crit Care Med. 2009 Jul;10(4):500-4. [abstract] (File Cabinet)
  • Holubkov R, Dean JM, Berger J, Anand KJ, Carcillo J, Meert K, Zimmerman J, Newth C, Harrison R, Willson DF, Nicholson C; the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network. Is "rescue" therapy ethical in randomized controlled trials? Pediatr Crit Care Med. 2009 Jul;10(4):431-438. [abstract; full-text (pdf; 580K)] (File Cabinet)
  • Randolph AG. Management of acute lung injury and acute respiratory distress syndrome in children. Crit Care Med. 2009; 37:2448–2454 [abstract] (File Cabinet)
  • Piastra M, De Luca D, Pietrini D, Pulitanò S, D'Arrigo S, Mancino A, Conti G. Noninvasive pressure-support ventilation in immunocompromised children with ARDS: a feasibility study. Intensive Care Med. 2009 Aug;35(8):1420-7. [abstract] (File Cabinet, EB Journal Club)
  • Khemani RG, Conti D, Alonzo TA, Bart RD 3rd, Newth CJ. Effect of tidal volume in children with acute hypoxemic respiratory failure. Intensive Care Med. 2009 Aug;35(8):1428-37. [abstract] (File Cabinet, EB Journal Club)
  • Rey C, Alvarez F, De La Rua V, Medina A, Concha A, DĂ­az JJ, MenĂ©ndez S, Los Arcos M, Mayordomo-Colunga J. Mechanical complications during central venous cannulations in pediatric patients. Intensive Care Med. 2009 Aug;35(8):1438-43. [abstract] (File Cabinet)

June 2009

  • McCaffrey J, Farrell C, Whiting P, Dan A, Bagshaw SM, Delaney AP. Corticosteroids to prevent extubation failure: a systematic review and meta-analysis. Intensive Care Med. 2009 Jun;35(6):977-86 [abstract] (File Cabinet, EB Journal Club)
  • Maloney-Wilensky E, Gracias V, Itkin A, Hoffman K, Bloom S, Yang W, Christian S, LeRoux PD. Brain tissue oxygen and outcome after severe traumatic brain injury: a systematic review. Crit Care Med. 2009 Jun;37(6):2057-63. [abstract] (File Cabinet)
  • Annane D, Bellissant E, Bollaert PE, Briegel J, Confalonieri M, De Gaudio R, Keh D, Kupfer Y, Oppert M, Merduri GU. Corticosteroids in the Treatment of Severe Sepsis and Septic Shock in Adults: A Systematic Review. JAMA. 2009; 301:2362-2375. [abstract] (File Cabinet, EB Journal Club)
  • Bronicki RA, Anas NG. Cardiopulmonary interaction. Pediatr Crit Care Med. 2009 May;10(3):313-22. [abstract] (File Cabinet)
  • Marchick MR, Kline JA, Jones AE. The significance of non-sustained hypotension in emergency department patients with sepsis. Intensive Care Med. 2009 Jul;35(7):1261-4. [abstract] (File Cabinet, EB Journal Club)
  • DĂĽnser MW, Takala J, Ulmer H, Mayr VD, Luckner G, Jochberger S, Daudel F, Lepper P, Hasibeder WR, Jakob SM. Arterial blood pressure during early sepsis and outcome. Intensive Care Med. 2009 Jul;35(7):1225-33. [abstract] (File Cabinet, EB Journal Club)
  • Poomthavorn P, Lertbunrian R, Preutthipan A, Sriphrapradang A, Khlairit P, Mahachoklertwattana P. Serum free cortisol index, free cortisol, and total cortisol in critically ill children. Intensive Care Med. 2009 Jul;35(7):1281-5. [abstract] (File Cabinet)
  • Moler FW, Meert K, Donaldson AE, Nadkarni V, Brilli RJ, Dalton HJ, Clark RS, Shaffner DH, Schleien CL, Statler K, Tieves KS, Hackbarth R, Pretzlaff R, van der Jagt EW, Levy F, Hernan L, Silverstein FS, Dean JM; Pediatric Emergency Care Applied Research Network. In-hospital versus out-of-hospital pediatric cardiac arrest: a multicenter cohort study. Crit Care Med. 2009 Jul;37(7):2259-67. [abstract] (File Cabinet)
  • Siempos II, Kopterides P, Tsangaris I, Dimopoulou I, Armaganidis AE. Impact of catheter-related bloodstream infections on the mortality of critically ill patients: a meta-analysis. Crit Care Med. 2009 Jul;37(7):2283-9. [abstract] (File Cabinet, EB Journal Club)

May 2009

  • Cummings P. The relative merits of risk ratios and odds ratios. Arch Pediatr Adolesc Med. 2009 May;163(5):438-45. [abstract] (EB Resources)
  • Bigham MT, Amato R, Bondurrant P, Fridriksson J, Krawczeski CD, Raake J, Ryckman S, Schwartz S, Shaw J, Wells D, Brilli RJ. Ventilator-Associated Pneumonia in the Pediatric Intensive Care Unit: Characterizing the Problem and Implementing a Sustainable Solution. J Pediatr. 2009; 154:582-7. [abstract] (File Cabinet, EB Journal Club)
  • Gow KW, Heiss KF, Wulkan ML, Katzenstein HM, Rosenberg ES, Heard ML, Rycus PT, Fortenberry JD. Extracorporeal life support for support of children with malignancy and respiratory or cardiac failure: The extracorporeal life support experience. Crit Care Med. 2009 Apr;37(4):1308-16. [abstract] (File Cabinet)
  • Kimberly HH, Shah S, Marill K, Noble V. Correlation of optic nerve sheath diameter with direct measurement of intracranial pressure. Acad Emerg Med. 2008 Feb;15(2):201-4. [abstract] (File Cabinet, EB Journal Club)
  • Tibballs J, Kinney S. Reduction of hospital mortality and of preventable cardiac arrest and death with increased survival on introduction of a pediatric medical emergency team. Pediatr Crit Care Med. 2009; 10:306–312. [abstract; full-text (pdf; 220K)] (File Cabinet, EB Journal Club)
  • Castillo L, Carcillo J. Secondary HLH and severe sepsis/SIRS/MODS/MAS share common intermediate phenotypes on a spectrum of inflammation. Pediatr Crit Care Med. 2009; 10(3):387-392. [abstract] (File Cabinet)
  • Antommaria AH, Trotochaud K, Kinlaw K, Hopkins PN, Frader J. Policies on donation after cardiac death at children's hospitals: a mixed-methods analysis of variation. JAMA. 2009; 301:1902-1908. [abstract] (File Cabinet)
  • Plint AC, Johnson DW, Patel H, Wiebe N, Correll R, Brant R, Mitton C, Gouin S, Bhatt M, Joubert G, Black KJ, Turner T, Whitehouse S, Klassen TP; Pediatric Emergency Research Canada (PERC). Epinephrine and dexamethasone in children with bronchiolitis. N Engl J Med. 2009 May 14;360(20):2079-89. [abstract] (File Cabinet, EB Journal Club)

April 2009

  • Levitt JE, Bedi H, Calfee CS, Gould MK, Matthay MA. Identification of Early Acute Lung Injury at Initial Evaluation in an Acute Care Setting Prior to the Onset of Respiratory Failure. Chest. 2009; 135:936-943. [abstract] (File Cabinet, EB Journal Club)
  • Srinivasan R, Asselin J, Gildengorin G, Wiener-Kronish J, Flori HR. A prospective study of ventilator-associated pneumonia in children. Pediatrics. 2009 Apr;123(4):1108-15. [abstract] (File Cabinet, EB Journal Club)
  • The World Federation of Pediatric Intensive and Critical Care Societies newsletter. March 31, 2009 (vol 1 number 1) is here... (Organizations)
  • Invitation to participate in SAFE EPIC: Saline vs. Albumin Resuscitation - Extrapolation to Paediatric Intensive Care, an international single day cross sectional observational study. Organized and sponsored by the Paediatric Study Group of the Australia and New Zealand Intensive Care Society (ANZICS PSG)The invitation is here... (Clinical Research)
  • Wong HR, Cvijanovich N, Allen GL, Lin R, Anas N, Meyer K, Freishtat RJ, Monaco M, Odoms K, Sakthivel B, Shanley TP; for the Genomics of Pediatric SIRS/Septic Shock Investigators. Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum* Crit Care Med. 2009; 37(5):1558-1566 [abstract] (File Cabinet)
  • Tang BM, Craig JC, Eslick GD, Seppelt I, McLean AS. Use of corticosteroids in acute lung injury and acute respiratory distress syndrome: A systematic review and meta-analysis* Crit Care Med. 2009; 37:1594-1603. [abstract] (File Cabinet, EB Journal Club)
  • Mikkelsen ME, Miltiades AN, Gaieski DF, Goyal M, Fuchs BD, Shah CV, Bellamy SL, Christie JD. Serum lactate is associated with mortality in severe sepsis independent of organ failure and shock* Crit Care Med. 2009; 37:1670 –1677 [abstract] (File Cabinet, EB Journal Club)
  • Fahy BG, Sheehy AM, Coursin DB. Glucose control in the intensive care unit. Crit Care Med. 2009 May;37(5):1769-76 [abstract] (File Cabinet)
  • Reader TW, Flin R, Mearns K, Cuthbertson BH. Developing a team performance framework for the intensive care unit. Crit Care Med. 2009 May;37(5):1787-93. [abstract] (File Cabinet)
  • Welke KF, O'Brien SM, Peterson ED, Ungerleider RM, Jacobs ML, Jacobs JP. The complex relationship between pediatric cardiac surgical case volumes and mortality rates in a national clinical database. J Thorac Cardiovasc Surg. 2009 May;137(5):1133-40 [abstract] (File Cabinet, EB Journal Club)

March 2009

  • Payen D, Mateo J, Cavaillon JM, Fraisse F, Floriot C, Vicaut E; Hemofiltration and Sepsis Group of the Collège National de RĂ©animation et de MĂ©decine d'Urgence des HĂ´pitaux extra-Universitaires.Impact of continuous venovenous hemofiltration on organ failure during the early phase of severe sepsis: a randomized controlled trial. Crit Care Med. 2009 Mar;37(3):803-10. [abstract] (File Cabinet, EB Journal Club)
  • Russell JA, Walley KR, Gordon AC, Cooper DJ, HĂ©bert PC, Singer J, Holmes CL, Mehta S, Granton JT, Storms MM, Cook DJ, Presneill JJ; Dieter Ayers for the Vasopressin and Septic Shock Trial Investigators. Interaction of vasopressin infusion, corticosteroid treatment, and mortality of septic shock. Crit Care Med. 2009 Mar;37(3):811-8. [abstract] (File Cabinet, EB Journal Club)
  • Thiel SW, Asghar MF, Micek ST, Reichley RM, Doherty JA, Kollef MH. Hospital-wide impact of a standardized order set for the management of bacteremic severe sepsis. Crit Care Med. 2009 Mar;37(3):819-24. [abstract] (File Cabinet)
  • Froehlich CD, Rigby MR, Rosenberg ES, Li R, Roerig PL, Easley KA, Stockwell JA. Ultrasound-guided central venous catheter placement decreases complications and decreases placement attempts compared with the landmark technique in patients in a pediatric intensive care unit. Crit Care Med. 2009 Mar;37(3):1090-6. [abstract] (File Cabinet, EB Journal Club)
  • Nishisaki A, Hales R, Biagas K, Cheifetz I, Corriveau C, Garber N, Hunt E, Jarrah R, McCloskey J, Morrison W, Nelson K, Niles D, Smith S, Thomas S, Tuttle S, Helfaer M, Nadkarni V. A multi-institutional high-fidelity simulation "boot camp" orientation and training program for first year pediatric critical care fellows. Pediatr Crit Care Med. 2009 Mar;10(2):157-162. [abstract] (File Cabinet)
  • Sorce LR, Hamilton SM, Gauvreau K, Mets MB, Hunter DG, Rahmani B, Wu C, Curley MA. Preventing corneal abrasions in critically ill children receiving neuromuscular blockade: A randomized, controlled trial. Pediatr Crit Care Med. 2009 Mar;10(2):171-175. [abstract] (File Cabinet, EB Journal Club)
  • Pleacher KM, Roach ES, Van der Werf W, Antommaria AH, Bratton SL. Impact of a pediatric donation after cardiac death program. Pediatr Crit Care Med. 2009 Mar;10(2):166-170. [abstract] (File Cabinet)
  • Hartman ME, McCrory DC, Schulman SR. Efficacy of sedation regimens to facilitate mechanical ventilation in the pediatric intensive care unit: A systematic review. Pediatr Crit Care Med. 2009 Mar;10(2):246-55. [abstract] (File Cabinet)
  • Veldhoen ES, Hartman BJ, van Gestel JP. Monitoring biochemical parameters as an early sign of propofol infusion syndrome: False feeling of security. Pediatr Crit Care Med. 2009 Mar;10(2):e19-21. [abstract] (Case Reports)
  • Sarnaik AP. Lessons learned in the life of a pediatric intensivist. Pediatr Crit Care Med. 2009 Mar;10(2):239-41. [abstract; full-text (pdf; 92K)] (File Cabinet)
  • Khemani RG, Patel NR, Bart RD 3rd, Newth CJ. Comparison of the Pulse Oximetric Saturation/Fraction of Inspired Oxygen Ratio and the PaO2/Fraction of Inspired Oxygen Ratio in Children. Chest. 2009 Mar;135(3):662-8 [abstract] (File Cabinet, EB Journal Club)
  • Anton N, Cox PN, Massicotte MP, Chait P, Yasui Y, Dinyari PM, Marzinotto V, Mitchell LG. Heparin-bonded central venous catheters do not reduce thrombosis in infants with congenital heart disease: a blinded randomized, controlled trial. Pediatrics. 2009 Mar;123(3):e453-8. [abstract] (File Cabinet, EB Journal Club)
  • Czaja AS, Zimmerman JJ, Nathens AB. Readmission and late mortality after pediatric severe sepsis. Pediatrics. 2009 Mar;123(3):849-57. [abstract] (File Cabinet, EB Journal Club)
  • Newall F, Johnston L, Ignjatovic V, Monagle P. Unfractionated heparin therapy in infants and children. Pediatrics. 2009 Mar;123(3):e510-8. [abstract] (File Cabinet)
  • Meeting minutes from the SCCM Pediatric Section committees are online: Business section here... (pdf; 560K); A report on our journal, Pediatric Critical Care Medicine, given by editor Pat Kochanek is here... (pdf; 600K)
    ; Newsletter and Minutes from the Fellowship Directors meeting are here... (pdf; 93K); APN Committee minutes are here... (pdf; 76K); Resident Education Committee minutes are here... (pdf; 73K) (Organizations/Meetings)
  • October TW, Hardart GE. Successful placement of postpyloric enteral tubes using electromagnetic guidance in critically ill children. Pediatr Crit Care Med. 2009 Mar;10(2):196-200. [abstract] (File Cabinet, EB Journal Club)
  • The preliminary Section on Critical Care program schedule at the AAP NCE in Washington DC, October 17-20, 2009, is now available online via the SOCC website here.... This includes a special 25-Year SOCC Anniversary program and celebration. (Organizations/Meetings)
  • Maclaren G, Butt W. Controversies in paediatric continuous renal replacement therapy. Intensive Care Med. 2009 Apr;35(4):596-602 [abstract] (File Cabinet)
  • The NICE-SUGAR Study Investigators. Intensive versus Conventional Glucose Control in Critically Ill Patients. N Engl J Med. 2009; 360:1283-1297. [abstract] (File Cabinet, EB Journal Club)
  • Timsit JF, Schwebel C, Bouadma L, Geffroy A, Garrouste-Orgeas M, Pease S, Herault MC, Haouache H, Calvino-Gunther S, Gestin B, Armand-Lefevre L, Leflon V, Chaplain C, Benali A, Francais A, Adrie C, Zahar JR, Thuong M, Arrault X, Croize J, Lucet JC; Dressing Study Group. Chlorhexidine-impregnated sponges and less frequent dressing changes for prevention of catheter-related infections in critically ill adults: a randomized controlled trial. JAMA. 2009 Mar 25;301(12):1231-41. [abstract] (File Cabinet, EB Journal Club)

February 2009

  • Holick MF, Lim R, Dighe AS. Case 3-2009 -- A 9-Month-Old Boy with Seizures. N Engl J Med. 2009 Jan 22;360(4):398-407 [citation] (Case Reports)
  • Mack EH, Wheeler DS, Embi PJ. Clinical decision support systems in the pediatric intensive care unit. Pediatr Crit Care Med. 2009 Jan;10(1):23-8. [abstract] (Clinical Resources, File Cabinet)
  • Riker RR, Shehabi Y, Bokesch PM, Ceraso D, Wisemandle W, Koura F, Whitten P, Margolis BD, Byrne DW, Ely EW, Rocha MG; for the SEDCOM (Safety and Efficacy of Dexmedetomidine Compared With Midazolam) Study Group. Dexmedetomidine vs Midazolam for Sedation of Critically Ill Patients: A Randomized Trial. JAMA. 2009; 301(5):489-499 [abstract] (File Cabinet, EB Journal Club)
  • Price JF, Mott AR, Dickerson HA, Jefferies JL, Nelson DP, Chang AC, O'Brian Smith E, Towbin JA, Dreyer WJ, Denfield SW, Goldstein SL. Worsening renal function in children hospitalized with decompensated heart failure: evidence for a pediatric cardiorenal syndrome? Pediatr Crit Care Med. 2008 May;9(3):279-84. [abstract] (File Cabinet, EB Journal Club)
  • Brierley J, Carcillo J, Choong K, et al. 2007 American College of Critical Care Medicine clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock* Crit Care Med. 2009; 37(2):666-688 [abstract] (File Cabinet)
  • Vlasselaers D, Milants I, Desmet L, Wouters PJ, Vanhorebeek I, van den Heuvel I, Mesotten D, Casaer MP, Meyfroidt G, Ingels C, Muller J, Van Cromphaut S, Schetz M, Van den Berghe G. Intensive insulin therapy for patients in paediatric intensive care: a prospective, randomised controlled study. Lancet. 2009 Jan 26 (epub ahead of print: DOI)[abstract] (File Cabinet, EB Journal Club)
  • Khemani RG, Bart RD, Alonzo TA, Hatzakis G, Hallam D, Newth CJ. Disseminated intravascular coagulation score is associated with mortality for children with shock. Intensive Care Med. 2009 Feb;35(2):327-33. [abstract] (File Cabinet, EB Journal Club)
  • Willson DF, Chess PR, Notter RH. Surfactant for pediatric acute lung injury.Pediatr Clin North Am. 2008 Jun;55(3):545-75. Review. [abstract] (File Cabinet)
  • Carcillo JA. Multiple organ system extracorporeal support in critically ill children. Pediatr Clin North Am. 2008 Jun;55(3):617-46. Review. [abstract] (File Cabinet)
  • Mayordomo-Colunga J, Medina A, Rey C, Díaz JJ, Concha A, Los Arcos M, Menéndez S. Predictive factors of non invasive ventilation failure in critically ill children: a prospective epidemiological study. Intensive Care Med. 2009 Mar;35(3):527-536. [abstract] (File Cabinet, EB Journal Club)
  • Evidence Based Decision Making in Critical Care, from Northern Clinical School, Faculty of Medicine, University of Sydney (EB Resources)

January 2009

  • An update regarding participation in the Critical Pertussis Study is here... (Clinical Research)
  • Cinel I, Opal SM. Molecular biology of inflammation and sepsis: A primer. Crit Care Med. 2009 Jan;37(1):291-304. [abstract] (File Cabinet)
  • de Smet AM, Kluytmans JA, Cooper BS, et al. Decontamination of the Digestive Tract and Oropharynx in ICU Patients. N Engl J Med. 2009 Jan 1;360(1):20-31. [abstract] (File Cabinet, EB Journal Club)
  • Neufeld RE, Clark BG, Robertson CM, Moddemann DM, Dinu IA, Joffe AR, Sauve RS, Creighton DE, Zwaigenbaum L, Ross DB, Rebeyka IM; Western Canadian Complex Pediatric Therapies Follow-up Group. Five-year neurocognitive and health outcomes after the neonatal arterial switch operation. J Thorac Cardiovasc Surg. 2008 Dec;136(6):1413-1421.e2. [abstract] (File Cabinet, EB Journal Club)
  • Meckler GD, Lowe C. To intubate or not to intubate? Transporting infants on prostaglandin E1. Pediatrics. 2009 Jan;123(1):e25-30. [abstract] (File Cabinet)
  • Franck LS, Harris SK, Soetenga DJ, Amling JK, Curley MA. The Withdrawal Assessment Tool-1 (WAT-1): an assessment instrument for monitoring opioid and benzodiazepine withdrawal symptoms in pediatric patients. Pediatr Crit Care Med. 2008 Nov;9(6):573-80. [abstract] (File Cabinet, EB Journal Club)
  • The Pediatric Section meetings at SCCM in Nashville are here... (pdf; 28K) (Organizations/Meetings)
  • Marik PE. Critical illness-related corticosteroid insufficiency. Chest. 2009 Jan;135(1):181-93. [abstract] (File Cabinet)
  • Newth CJ, Venkataraman S, Willson DF, Meert KL, Harrison R, Dean JM, Pollack M, Zimmerman J, Anand KJ, Carcillo JA, Nicholson CE; Eunice Shriver Kennedy National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network. Weaning and extubation readiness in pediatric patients. Pediatr Crit Care Med. 2009 Jan;10(1):1-11. [abstract; full-text (pdf; 730K)] (File Cabinet)
  • Proulx F, Joyal JS, Mariscalco MM, Leteurtre S, Leclerc F, Lacroix J. The pediatric multiple organ dysfunction syndrome. Pediatr Crit Care Med. 2009 Jan;10(1):12-22. [abstract] (File Cabinet)
  • Attia J, Ioannidis JP, Thakkinstian A, McEvoy M, Scott RJ, Minelli C, Thompson J, Infante-Rivard C, Guyatt G. How to use an article about genetic association: A: Background concepts. JAMA. 2009 Jan 7;301(1):74-81. [abstract] (EB Resources)
  • Attia J, Ioannidis JP, Thakkinstian A, McEvoy M, Scott RJ, Minelli C, Thompson J, Infante-Rivard C, Guyatt G. How to use an article about genetic association: B: Are the results of the study valid? JAMA. 2009 Jan 14;301(2):191-7. [abstract] (EB Resources)
  • Attia J, Ioannidis JP, Thakkinstian A, McEvoy M, Scott RJ, Minelli C, Thompson J, Infante-Rivard C, Guyatt G. How to use an article about genetic association: C: What are the results and will they help me in caring for my patients? JAMA. 2009 Jan 21;301(3):304-8. [abstract] (EB Resources)
  • Feihl F, Broccard AF. Interactions between respiration and systemic hemodynamics. Part I: basic concepts. Intensive Care Med. 2009 Jan;35(1):45-54. [abstract] (File Cabinet)
  • Yu WL, Lu ZJ, Wang Y, Shi LP, Kuang FW, Qian SY, Zeng QY, Xie MH, Zhang GY, Zhuang DY, Fan XM, Sun B; Collaborative Study Group of Pediatric Respiratory Failure. The epidemiology of acute respiratory distress syndrome in pediatric intensive care units in China. Intensive Care Med. 2009 Jan;35(1):136-43 [abstract] (File Cabinet)

December 2008

  • Borasino S, Morrison W, Silberman J, Nelson RM, Feudtner C. Physicians' Contact With Families After the Death of Pediatric Patients: A Survey of Pediatric Critical Care Practitioners' Beliefs and Self-Reported Practices. Pediatrics. 2008; 122:e1174-e1178 [abstract] (File Cabinet)
  • Domi T, Edgell DS, McCrindle BW, et al. Frequency, Predictors, and Neurologic Outcomes of Vaso-occlusive Strokes Associated With Cardiac Surgery in Children Pediatrics 2008;122: 1292-1298 [abstract] (File Cabinet, EB Journal Club)
  • Knoester H, Sol JJ, Ramsodit P, et al. Cardiac Function in Pediatric Septic Shock Survivors. Arch Pediatr Adolesc Med. 2008; 162:1164-1168 [abstract] (File Cabinet, EB Journal Club)
  • Changes at the NIH regarding the peer review process:
  • Yañez LJ, Yunge M, Emilfork M, Lapadula M, Alcántara A, Fernández C, Lozano J, Contreras M, Conto L, Arevalo C, Gayan A, Hernández F, Pedraza M, Feddersen M, Bejares M, Morales M, Mallea F, Glasinovic M, Cavada G. A prospective, randomized, controlled trial of noninvasive ventilation in pediatric acute respiratory failure. Pediatr Crit Care Med. 2008 Sep;9(5):484-9. [abstract] (File Cabinet, EB Journal Club)
  • The third newsletter of the World Federation of Pediatric Intensive and Critical Care Societies (WFPICSS) is here... (pdf; 380K) (Organizations)
  • Mathews SC, Pronovost PJ. Physician Autonomy and Informed Decision Making: Finding the Balance for Patient Safety and Quality JAMA. 2008;300(24):2913-2915. [extract]
  • Zappitelli M, Goldstein SL, Symons JM, Somers MJ, Baum MA, Brophy PD, Blowey D, Fortenberry JD, Chua AN, Flores FX, Benfield MR, Alexander SR, Askenazi D, Hackbarth R, Bunchman TE; Prospective Pediatric Continuous Renal Replacement Therapy Registry Group. Protein and calorie prescription for children and young adults receiving continuous renal replacement therapy: a report from the Prospective Pediatric Continuous Renal Replacement Therapy Registry Group. Crit Care Med. 2008 Dec;36(12):3239-45. [abstract] (File Cabinet)
  • Weisberg LS. Management of severe hyperkalemia. Crit Care Med. 2008 Dec;36(12):3246-51 [abstract] (File Cabinet)

November 2008

  • The November 2008 WFPICCS newsletter is now available here... (Organizations)
  • Miller MP, Sagy M. Pressure Characteristics of Mechanical Ventilation and Incidence of Pneumothorax Before and After the Implementation of Protective Lung Strategy (PLS) in the Management of Pediatric Patients with Severe ARDS. Chest. 2008; 134 969-973. [abstract] (File Cabinet, EB Journal Club)
  • Devictor DJ, Tissieres P, Gillis J, Truog R; for the WFPICCS task-force on Ethics. Intercontinental differences in end-of-life attitudes in the pediatric intensive care unit. Results of a worldwide survey. Pediatr Crit Care Med. 2008; 9(6):560-566. [abstract] (File Cabinet)
  • Rafaat KT, Spear RM, Kuelbs C, Parsapour K, Peterson B. Cranial computed tomographic findings in a large group of children with drowning: Diagnostic, prognostic, and forensic implications. Pediatr Crit Care Med. 2008; 9(6):567-572 [abstract] (File Cabinet, EB Journal Club)
  • Marik PE, Zaloga GP. Immunonutrition in critically ill patients: a systematic review and analysis of the literature. Intensive Care Med. 2008 Nov;34(11):1980-90 [abstract] (File Cabinet, EB Journal Club)
  • Lamas A, LĂłpez-Herce J, Sancho L, MencĂ­a S, Carrillo A, Santiago MJ, MartĂ­nez V. Assessing sedation in critically ill children by bispectral index, auditory-evoked potentials and clinical scales. Intensive Care Med. 2008 Nov;34(11):2092-9 [abstract] (File Cabinet)
  • Calzavacca P, Licari E, Tee A, Egi M, Haase M, Haase-Fielitz A, Bellomo R. A prospective study of factors influencing the outcome of patients after a Medical Emergency Team review. Intensive Care Med. 2008 Nov;34(11):2112-6. [abstract] (File Cabinet)
  • Pre-Application Meeting For RFAHD-08-025 "Collaborative Pediatric Critical Care Research Program" and RFA-HD-08-027 "Data Coordinating Center For The Collaborative Pediatric Critical Care Research Program." December 3, 2008, Bethesda MD. Full meeting details are here... (pdf 60K) and the official announcement here... (Research)
  • Montañana PA, I Alapont VM, OcĂłn AP, LĂłpez PO, Prats JL, Parreño JD. The use of isotonic fluid as maintenance therapy prevents iatrogenic hyponatremia in pediatrics: A randomized, controlled open study. Pediatr Crit Care Med. 2008; 9(6):589-597. [abstract; full-text (pdf 788K) (File Cabinet, EB Journal Club)
  • Seear MD, Scarfe JC, Leblanc JG. Predicting major adverse events after cardiac surgery in children. Pediatr Crit Care Med. 2008; 9:606-611. [abstract] (File Cabinet, EB Journal Club)
  • Talmor D, Sarge T, Malhotra A, O'Donnell CR, Ritz R, Lisbon A, Novack V, Loring SH. Mechanical Ventilation Guided by Esophageal Pressure in Acute Lung Injury. N Engl J Med. 2008; 359:2095-104 [abstract] (File Cabinet, EB Journal Club)
  • Joffe AR, Anton NR, deCaen AR. Survey of pediatricians' opinions on donation after cardiac death: are the donors dead? Pediatrics. 2008 Nov;122(5):e967-74. [abstract] (File Cabinet)
  • Topjian AA, Berg RA, Nadkarni VM. Pediatric cardiopulmonary resuscitation: advances in science, techniques, and outcomes. Pediatrics. 2008 Nov;122(5):1086-98. [abstract] (File Cabinet)
  • Arabi YM, Dabbagh OC, Tamim HM, Al-Shimemeri AA, Memish ZA, Haddad SH, Syed SJ, Giridhar HR, Rishu AH, Al-Daker MO, Kahoul SH, Britts RJ, Sakkijha MH. Intensive versus conventional insulin therapy: A randomized controlled trial in medical and surgical critically ill patients. Crit Care Med. 2008; 36(12):3190-3197 [abstract] (File Cabinet, EB Journal Club)
  • Fan E, Wilcox ME, Brower RG, Stewart TE, Mehta S, Lapinsky SE, Meade MO, Ferguson ND. Recruitment Maneuvers for Acute Lung Injury: A Systematic Review. Am J Respir Crit Care Med. 2008; 178 1156-1163 [abstract] (File Cabinet, EB Journal Club)
  • SearchingPediatrics.com is a new search tool for peer-reviewed pediatric resources on the web. (Internet Resources)
  • Trzeciak S, McCoy JV, Phillip Dellinger R, Arnold RC, Rizzuto M, Abate NL, Shapiro NI, Parrillo JE, Hollenberg SM; on behalf of the Microcirculatory Alterations in Resuscitation and Shock (MARS) investigators. Early increases in microcirculatory perfusion during protocol-directed resuscitation are associated with reduced multi-organ failure at 24 h in patients with sepsis. Intensive Care Med. 2008 Dec;34(12):2210-221 [abstract] (File Cabinet, EB Journal Club)
  • VallĂ©e F, Vallet B, Mathe O, Parraguette J, Mari A, Silva S, Samii K, Fourcade O, Genestal M. Central venous-to-arterial carbon dioxide difference: an additional target for goal-directed therapy in septic shock? Intensive Care Med. 2008 Dec;34(12):2218-2225. [abstract] (File Cabinet, EB Journal Club)
  • http://www.ncbi.nlm.nih.gov/pubmed/18629472?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum (File Cabinet, EB Journal Club)
  • Children & Clinical Studies: an NIH-developed website to explain clinical research to children and families - why it is needed, what to expect, how to identify additional reliable resources. (Websites, clinical research)
  • Echocardiographic Evaluation of Congenital Heart Disease; an excellent compilation of resources on the web. Echocardiography Labratory at Childrens Hospital Los Angeles (File Cabinet)

October 2008

  • Needham DM. Mobilizing patients in the Intensive Care Unit: Improving Neuromuscular Weakness and Physical Function JAMA 2008;300(14):1685-1690 [abstract] (File Cabinet)
  • Anderson J, Leonard D, Braner DAV, Lai S, Tegtmeyer K. Umbilical vascular catheterization. New Engl J Med 2008; 359:e18 [video] (File Cabinet)
  • Honeycutt TC, El Khashab M, Wardrop RM 3rd, McNeal-Trice K, Honeycutt AL, Christy CG, Mistry K, Harris BD, Meliones JN, Kocis KC. Probiotic administration and the incidence of nosocomial infection in pediatric intensive care: a randomized placebo-controlled trial. Pediatr Crit Care Med. 2007 Sep;8(5):452-8 [abstract] (File Cabinet)
  • Montagnino BA, Ethier AM. The experiences of pediatric nurses caring for children in a persistent vegetative state. Pediatr Crit Care Med. 2007 Sep;8(5):440-6. [abstract] (File Cabinet, EB Journal Club)
  • Carnevale FA, Canoui P, Cremer R, Farrell C, Doussau A, Seguin MJ, Hubert P, Leclerc F, Lacroix J. Parental involvement in treatment decisions regarding their critically ill child: a comparative study of France and Quebec. Pediatr Crit Care Med. 2007 Jul;8(4):337-42. [abstract] (File Cabinet, EB Journal Club)
  • Curley MA, Harrison CH, Craig N, Lillehei CW, Micheli A, Laussen PC. Pediatric staff perspectives on organ donation after cardiac death in children. Pediatr Crit Care Med. 2007 May;8(3):212-9. [abstract] (File Cabinet, EB Journal Club)
  • Montor VM, Guyatt GH. Progress in Evidence-Based Medicine. JAMA. 2008; 300:1814-1816 [extract] (EB Resources)
  • Kleinpell RM, Ely EW, Grabenkort R. Nurse practitioners and physician assistants in the intensive care unit: an evidence-based review. Crit Care Med. 2008 Oct;36(10):2888-97. [abstract] (Nursing)
  • van Gestel JP, Bollen CW, van der Tweel I, Boelens JJ, van Vught AJ. Intensive care unit mortality trends in children after hematopoietic stem cell transplantation: a meta-regression analysis. Crit Care Med. 2008 Oct;36(10):2898-904. [abstract] (File Cabinet)
  • Zarychanski R, Doucette S, Fergusson D, Roberts D, Houston DS, Sharma S, Gulati H, Kumar A. Early intravenous unfractionated heparin and mortality in septic shock. Crit Care Med. 2008; 36(11):2973-2979 [abstract] (File Cabinet, EB Journal Club)
  • Post F, Weilemann LS, Messow CM, Sinning C, MĂĽnzel T. B-type natriuretic peptide as a marker for sepsis-induced myocardial depression in intensive care patients. Crit Care Med. 2008; 36(11):3030-3037 [abstract] (File Cabinet, EB Journal Club)
  • Marik PE, Corwin HL. Acute lung injury following blood transfusion: Expanding the definition. Crit Care Med. 2008; 36(11):3080-3084 [abstract] (File Cabinet)

September 2008

  • Wiener Soylemez R, Wiener DC, Larson RJ. Benefits and Risks of Tight Glucose Control in Critically Ill Adults: A Meta-analysis. JAMA. 2008; 300:933-944. [abstract] (File Cabinet, EB Journal Club)
  • Marik PE, Corwin HL. Efficacy of red blood cell transfusion in the critically ill: A systematic review of the literature. Crit Care Med. 2008; 36:2667-2674. [abstract] (File Cabinet, EB Journal Club)
  • Liu KD, Levitt J, Zhuo H, Kallet RH, Brady S, Steingrub J, Tidswell M, Siegel MD, Soto G, Peterson MW, Chesnutt MS, Phillips C, Weinacker A, Thompson BT, Eisner MD, Matthay MA. Randomized Clinical Trial of Activated Protein C for the Treatment of Acute Lung Injury. Am J Respir Crit Care Med. 2008; 178:618-623 [abstract] (File Cabinet, EB Journal Club)
  • The Laura P. and Leland K. Whittier Virtual Pediatric Intensive Care Unit announces the creation of a VPICU Fellowship Program. Read details and application instructions here... (pdf 150K) (VPICU)
  • Kon AA. Healthcare providers must offer palliative treatment to parents of neonates with hypoplastic left heart syndrome. Arch Pediatr Adolesc Med. 2008 Sep;162(9):844-8 [abstract] (File Cabinet)
  • Wernovsky G. The paradigm shift toward surgical intervention for neonates with hypoplastic left heart syndrome. Arch Pediatr Adolesc Med. 2008 Sep;162(9):849-54 [abstract] (File Cabinet)
  • Domico M, Liao P, Anas N, Mink RB. Elevation of brain natriuretic peptide levels in children with septic shock. Pediatr Crit Care Med. 2008; 9(5):478-483 [abstract] (File Cabinet, EB Journal Club)
  • Yañez LJ, Yunge M, Emilfork M, Lapadula M, Alcántara A, Fernández C, Hernández F, Catalán C, Conto L, Arevalo C, Landeros J. A prospective, randomized, controlled trial of noninvasive ventilation in pediatric acute respiratory failure. Pediatr Crit Care Med. 2008; 9:484-489 [abstract] (File Cabinet, EB Journal Club)
  • Wratney AT, Benjamin DK Jr, Slonim AD, He J, Hamel DS, Cheifetz IM. The endotracheal tube air leak test does not predict extubation outcome in critically ill pediatric patients. Pediatr Crit Care Med. 2008; 9:490-496 [abstract][full-text (pdf: 200K)](File Cabinet, EB Journal Club)
  • Staley KJ, Sims KB, Grand PE, Hedley-Whyte ET. Case 28-2008 — An 8-Day-Old Infant with Congenital Deafness, Lethargy, and Hypothermia. New Engl J Med 2008; 359:1156-1167 [full-text for subscribers] (Case Reports)

August 2008

  • AACN Standards for Establishing and Sustaining Healthy Work Environments (pdf; 2MB) (Nursing)
  • Fong JJ, Sylvia L, Ruthazer R, Schumaker G, Kcomt M, Devlin JW. Predictors of mortality in patients with suspected propofol infusion syndrome. Crit Care Med. 2008 Aug;36(8):2281-7. [abstract] (File Cabinet, EB Journal Club)
  • Ista E, van Dijk M, Gamel C, Tibboel D, de Hoog M. Withdrawal symptoms in critically ill children after long-term administration of sedatives and/or analgesics: A first evaluation. Crit Care Med. 2008; 36(8):2427-2432. [abstract] (File Cabinet)
  • Principi T, Morrison GC, Matsui DM, Speechley KN, Seabrook JA, Singh RN, Kornecki A. Elective tracheostomy in mechanically ventilated children in Canada. Intensive Care Med. 2008 Aug;34(8):1498-502. [abstract] (File Cabinet)
  • Mercurio MR, Peterec SM, Weeks B. Hypoplastic left heart syndrome, extreme prematurity, comfort care only, and the principle of justice. Pediatrics. 2008 Jul;122(1):186-9 [citation] (File Cabinet)
  • Choong K, Kissoon N. Vasopressin in pediatric shock and cardiac arrest. Pediatr Crit Care Med. 2008; 9:372-379. [abstract; full-text (pdf: 200K) (File Cabinet)
  • Boucek MM, Mashburn C, Dunn SM, et al. Pediatric Heart Transplantation after Declaration of Cardiocirculatory Death. New Engl J Med 2008; 359:709-714. [full-text]. This issue includes several relevant and thought-provoking commentaries, including: Truog RD, Miller FG. The Dead Donor Rule and Organ Transplantation. New Engl J Med 2008; 359:674-675. [full-text] (File Cabinet)
  • The 2008 AAP National Conference and Exhibition is in Boston, October 11-14. The SOCC program is here... (pdf; 600K) (Meetings)
  • The AAP SOCC Summer 2008 newsletter is here... (pdf; 1.2MB)
  • Kollef MH, Afessa B, Anzueto A, et al. for the NASCENT Investigation Group. Silver-Coated Endotracheal Tubes and Incidence of Ventilator-Associated Pneumonia: The NASCENT Randomized Trial. JAMA. 2008;300(7):805-813. [abstract] (File Cabinet, EB Journal Club)
  • Javouhey E, Barats A, Richard N, Stamm D, Floret D. Non-invasive ventilation as primary ventilatory support for infants with severe bronchiolitis. Intensive Care Med. 2008 Sep;34(9):1608-14 [abstract] (File Cabinet, EB Journal Club)
  • Hauser GJ, Kaufman SS, Matsumoto CS, Fishbein TM. Pediatric intestinal and multivisceral transplantation: a new challenge for the pediatric intensivist. Intensive Care Med. 2008 Sep;34(9):1570-9 [abstract] (File Cabinet)
  • Wolfler A, Silvani P, Musicco M, Antonelli M, Salvo I; on behalf of the Italian Pediatric Sepsis Study (SISPe) group. Incidence of and mortality due to sepsis, severe sepsis and septic shock in Italian Pediatric Intensive Care Units: a prospective national survey. Intensive Care Med. 2008 Sep;34(9):1690-1697 [abstract] (File Cabinet)
  • Plötz FB, Bouma AB, van Wijk JA, Kneyber MC, Bökenkamp A. Pediatric acute kidney injury in the ICU: an independent evaluation of pRIFLE criteria. Intensive Care Med. 2008 Sep;34(9):1713-7 [abstract] (File Cabinet)
  • Klein GW, Hojsak JM, Schmeidler J, Rapaport R. Hyperglycemia and Outcome in the Pediatric Intensive Care Unit. J Pediatr 2008; 153:379-384. [abstract] (File Cabinet, EB Journal Club)
  • The Collaborative Pediatric Critical Care Research Network (CPCCRN): A renewal RFA has been issued (U10) for site application here... And the Data Coordinating Center RFA is here... (Clinical Research)

July 2008

  • Tsui JY, Caoolins AB, White DW, Lai J, Tabas JA. Placement of a Femoral Venous Catheter. New Engl J Med 2008; 358:e30 [video link] (File Cabinet)
  • Gueugniaud PV, David JS, Chanzy E, et al. Vasopressin and Epinephrine vs. Epinephrine Alone in Cardiopulmonary Resuscitation. New Engl J Med 2008; 359:21-30. [abstract] (File Cabinet, EB Journal Club)
  • Abroug F, Ouanes-Besbes L, Elatrous S, Brochard L. The effect of prone positioning in acute respiratory distress syndrome or acute lung injury: a meta-analysis. Areas of uncertainty and recommendations for research. Intensive Care Med. 2008 Jun;34(6):1002-11 [abstract] (File Cabinet, EB Journal Club)
  • Knoester H, Bronner MB, Bos AP. Surviving pediatric intensive care: physical outcome after 3 months. Intensive Care Med. 2008 Jun;34(6):1076-1082 [abstract] (File Cabinet, EB Journal Club)
  • Tissières P, da Cruz E, Habre W, Aggoun Y, Mensi N, Kalangos A, Beghetti M. Value of brain natriuretic peptide in the perioperative follow-up of children with valvular disease. Intensive Care Med. 2008 Jun;34(6):1109-13 [abstract] (File Cabinet, EB Journal Club)
  • The Pediatric Critical Care Scientist Development Program (PCCSDP) has been successfully reissued by the NICHD. Read the RFA here... This program is to foster the development of highly promising young faculty in pediatric critical care into physician scientists. Details of the program can be found at www.pccsdp.org (Clinical Research)
  • Gray A, Goodacre S, Newby DE, Masson M, Sampson F, Nicholl J; 3CPO Trialists. Noninvasive ventilation in acute cardiogenic pulmonary edema. N Engl J Med. 2008 Jul 10;359(2):142-51. [abstract] (File Cabinet, EB Journal Club)
  • Hirshberg E, Larsen G, Van Duker H. Alterations in glucose homeostasis in the pediatric intensive care unit: Hyperglycemia and glucose variability are associated with increased mortality and morbidity* Pediatr Crit Care Med. 2008; 9:361-366 [abstract] (File Cabinet, EB Journal Club)
  • Simon L, Saint-Louis P, Amre DK, Lacroix J, Gauvin F. Procalcitonin and C-reactive protein as markers of bacterial infection in critically ill children at onset of systemic inflammatory response syndrome* Pediatr Crit Care Med. 2008; 9:407-413 [abstract] (File Cabinet, EB Journal Club)
  • Knirsch W, Kretschmar O, Tomaske M, Stutz K, Nagdyman N, Balmer C, Schmitz A, BĂ©ttex D, Berger F, Bauersfeld U, Weiss M. Cardiac output measurement in children: comparison of the Ultrasound Cardiac Output Monitor with thermodilution cardiac output measurement. Intensive Care Med. 2008 Jun;34(6):1060-1064 [abstract] (File Cabinet, EB Journal Club)
  • Baghurst PA, Norton L, Slater A; for the ANZICS Paediatric Study Group. The application of risk-adjusted control charts using the Paediatric Index of Mortality 2 for monitoring paediatric intensive care performance in Australia and New Zealand. Intensive Care Med. 2008 Jul;34(7):1281-1288 [abstract] (File Cabinet)

June 2008

  • The first newsletter from the World Federation of Pediatric Intensive and Critical Care Societies (WFPICSS) (Organizations)
  • Hsiao J, Pacheco-Fowler V. Cricothyroidotomy. New Engl J Med 2008; 358:e25 (Videos in Clinical Medicine) [video] (File Cabinet)
  • Hutchison JS, Ward RE, Lacroix J, et al. for the Hypothermia Pediatric Head Injury Trial Investigators andt the Canadian Critical Care Trials Group. Hypothermia Therapy after Traumatic Brain Injury in Children. N Engl J Med 2008; 358; 2447-2456. [abstract] (File Cabinet, EB Journal Club)
  • The 7th International Symposium of the Pediatric Cardiac Critical Care Society will be held in Miami from December 2-6, 2008. (Organizations)
  • Naim MY, Hoehn KS, Hasz RD, White LS, Helfaer MA, Nelson RM. The Children's Hospital of Philadelphia's experience with donation after cardiac death. Crit Care Med. 2008 Jun;36(6):1729-33. [abstract] (File Cabinet)
  • Morris AH, Orme J Jr, Truwit JD, Steingrub J, Grissom C, Lee KH, Li GL, Thompson BT, Brower R, Tidswell M, Bernard GR, Sorenson D, Sward K, Zheng H, Schoenfeld D, Warner H. A replicable method for blood glucose control in critically Ill patients. Crit Care Med. 2008 Jun;36(6):1787-95. [abstract] (File Cabinet)
  • Rosenthal G, Hemphill JC 3rd, Sorani M, Martin C, Morabito D, Obrist WD, Manley GT. Brain tissue oxygen tension is more indicative of oxygen diffusion than oxygen delivery and metabolism in patients with traumatic brain injury. Crit Care Med. 2008 Jun;36(6):1917-24. [abstract] (File Cabinet)
  • Marik PE, Pastores SM, Annane D, Meduri GU, Sprung CL, Arlt W, Keh D, Briegel J, Beishuizen A, Dimopoulou I, Tsagarakis S, Singer M, Chrousos GP, Zaloga G, Bokhari F, Vogeser M; American College of Critical Care Medicine. Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: consensus statements from an international task force by the American College of Critical Care Medicine. Crit Care Med. 2008 Jun;36(6):1937-49. [abstract] (File Cabinet, EB Journal Club)
  • Bateman ST, Lacroix J, Boven K, Forbes P, Barton R, Thomas NJ, Jacobs B, Markovitz B, Goldstein B, Hanson JH, Li HA, Randolph AG. Anemia, Blood Loss, and Blood Transfusions in North American Children in the Intensive Care Unit. Am J Respir Crit Care Med. 2008 Apr 17. [Epub ahead of print] [abstract] (File Cabinet)

May 2008

  • Iscimen R, Cartin-Ceba R, Yilmaz M, Khan H, Hubmayr RD, Afessa B, Gajic O. Risk factors for the development of acute lung injury in patients with septic shock: an observational cohort study. Crit Care Med. 2008 May;36(5):1518-22. [abstract] (File Cabinet, EB Journal Club)
  • Huang SC, Wu ET, Chen YS, Chang CI, Chiu IS, Wang SS, Lin FY, Ko WJ. Extracorporeal membrane oxygenation rescue for cardiopulmonary resuscitation in pediatric patients. Crit Care Med. 2008 May;36(5):1607-13. [abstract] (File Cabinet, EB Journal Club)
  • Critical Care Nursing of Infants and Children. 2nd Edition. Curley MAQ, Moloney-Harmon PA, eds. 2001. (this edition is out of print and now freely available) (Nursing)
  • Tamburro RF, Barfield RC, Shaffer ML, Rajasekaran S, Woodard P, Morrison RR, Howard SC, Fiser RT, Schmidt JE, Sillos EM. Changes in outcomes (1996-2004) for pediatric oncology and hematopoietic stem cell transplant patients requiring invasive mechanical ventilation. Pediatr Crit Care Med. 2008 May;9(3):270-7. [abstract] (File Cabinet, EB Journal Club)
  • Kalyanaraman M, DeCampli WM, Campbell AI, Bhalala U, Harmon TG, Sandiford P, McMahon CK, Shore S, Yeh TS. Serial blood lactate levels as a predictor of mortality in children after cardiopulmonary bypass surgery. Pediatr Crit Care Med. 2008 May;9(3):285-8. [abstract] (File Cabinet, EB Journal Club)
  • Levin DL. Cerebral edema in diabetic ketoacidosis. Pediatr Crit Care Med. 2008 May;9(3):320-9. [abstract; full-text (pdf; 280K)] (File Cabinet)
  • Parienti JJ, Thirion M, MĂ©garbane B, et al; Members of the Cathedia Study Group. Femoral vs jugular venous catheterization and risk of nosocomial events in adults requiring acute renal replacement therapy: a randomized controlled trial. JAMA. 2008 May 28;299(20):2413-22. [abstract] (File Cabinet, EB Journal Club)
  • The VA/NIH Acute Renal Failure Trial Network. Intensity of Renal Support in Critically Ill Patients with Acute Kidney Injury. N Engl J Med. 2008 May 20. [Epub ahead of print] [abstract] (File Cabinet, EB Journal Club)

April 2008

  • Sarani B, Dunkman WJ, Dean L, Sonnad S, Rohrbach JI, Gracias VH. Transfusion of fresh frozen plasma in critically ill surgical patients is associated with an increased risk of infection. Crit Care Med. 2008 Apr;36(4):1114-8. [abstract] (File Cabinet, EB Journal Club)
  • Leal-Noval SR, Munoz-Gomez M, Arellano-Orden V, MarĂ­n-Caballos A, Amaya-Villar R, Marin A, Puppo-Moreno A, Ferrandiz-Millon C, Flores-Cordero JM, Murillo-Cabezas F. Impact of age of transfused blood on cerebral oxygenation in male patients with severe traumatic brain injury. Crit Care Med. 2008 Apr;36(4):1290-6. [abstract] (File Cabinet)
  • Wheeler DS, Devarajan P, Ma Q, Harmon K, Monaco M, Cvijanovich N, Wong HR. Serum neutrophil gelatinase-associated lipocalin (NGAL) as a marker of acute kidney injury in critically ill children with septic shock. Crit Care Med. 2008 Apr;36(4):1297-303. [abstract] (File Cabinet)
  • An G, West MA. Abdominal compartment syndrome: A concise clinical review. Crit Care Med. 2008 Apr;36(4):1304-10. [abstract] (File Cabinet)
  • Palevsky PM. Clinical review: timing and dose of continuous renal replacement therapy in acute kidney injury. Crit Care. 2007;11(6):232. [abstract] (see entire April 2008 supplement on acute kidney injury) (File Cabinet)
  • Kneyber MC, Brouwers AG, Caris JA, Chedamni S, Plötz FB. Acute respiratory distress syndrome: is it underrecognized in the pediatric intensive care unit? Intensive Care Med. 2008 Apr;34(4):751-4. [abstract] (File Cabinet)
  • Vinclair M, Broux C, Faure P, Brun J, Genty C, Jacquot C, Chabre O, Payen JF. Duration of adrenal inhibition following a single dose of etomidate in critically ill patients. Intensive Care Med. 2008 Apr;34(4):714-9 [abstract] (File Cabinet)
  • Ross Russell RI, Helms PJ, Elliott MJ. A prospective study of phrenic nerve damage after cardiac surgery in children. Intensive Care Med. 2008 Apr;34(4):728-734. [abstract] (File Cabinet) pdf; 56K] (File Cabinet)
  • World Federation of Pediatric and Intensive Care Societies (WFPICCS) Pediatric Sepsis Initiative Database is operational. Read more... (Organizations)
  • LĂłpez-Herce J, Santiago MJ, Sánchez C, MencĂ­a S, Carrillo A, Vigil D. Risk factors for gastrointestinal complications in critically ill children with transpyloric enteral nutrition. Eur J Clin Nutr. 2008 Mar;62(3):395-400 [abstract] (File Cabinet, EB Journal Club)
  • Andreasen JB, Johnsen SP, Ravn HB.Junctional ectopic tachycardia after surgery for congenital heart disease in children. Intensive Care Med. 2008 May;34(5):895-902. [abstract] (File Cabinet, EB Journal Club)
  • Minneci PC, Eichacker PQ, Danner RL, Banks SM, Natanson C, Deans KJ. The importance of usual care control groups for safety monitoring and validity during critical care research. Intensive Care Med. 2008 May;34(5):942-947. [abstract] (File Cabinet)
  • Eichenwald EC, Stark AR. Management and outcomes of very low birth weight. N Engl J Med. 2008 Apr 17;358(16):1700-11 [abstract] (File Cabinet)
  • Redline RW, Sagar P, King ME, Krishnamoorthy KS, Grabowski EF, Roberts DJ. Case records of the Massachusetts General Hospital. Case 12-2008. A newborn infant with intermittent apnea and seizures. N Engl J Med. 2008 Apr 17;358(16):1713-23 [citation] (Case Reports)
  • de Oliveira CF, de Oliveira DS, Gottschald AF, Moura JD, Costa GA, Ventura AC, Fernandes JC, Vaz FA, Carcillo JA, Rivers EP, Troster EJ. ACCM/PALS haemodynamic support guidelines for paediatric septic shock: an outcomes comparison with and without monitoring central venous oxygen saturation. Intensive Care Med. 2008 Mar 28; DOI 10.1007/s00134-008-1085-9. [abstract] (File Cabinet, EB Journal Club)

March 2008

  • Campbell ML, Curtis JR, Haas CE et al. Recommendations for end-of-life care in the intensive care unit: A consensus statement by the American Academy of Critical Care Medicine. Crit Care Med 2008; 36(3):953-963 [abstract] (File Cabinet)
  • Russell JA, Walley KR, Singer J, et al. for the VASST Investigators. Vasopressin versus norepinephrine infusion in patients with septic shock. New Engl J Med 2008; 358:877-87 [abstract] (File Cabinet, EB Journal Club)
  • Kinane, TB, Grabowski EF, Sharma A, et al. Case 7-2008 — A 17-Year-Old Girl with Chest Pain and Hemoptysis. New Engl J Med 2008; 358:941-952. [case introduction] (Case Reports)
  • Minutes from the Fellowship Directors meeting at the 2008 SCCM Congress are here... (pdf; 208K) (Organizations)
  • Mekontso-Dessap A, Leon R, Habibi A, et al. Pulmonary Hypertension and Cor Pulmonale during Severe Acute Chest Syndrome in Sickle Cell Disease. Am J Resp Crit Care Med 2008; 177:646-653. [abstract] (File Cabinet, EB Journal Club)
  • Yung M, Wilkins B, Norton L, Slater A, for the Paediatric Study Group; Australian and New Zealand Intensive Care Society. Glucose control, organ failure, and mortality in pediatric intensive care*. Pediatr Crit Care Med 2008; 9(2):147-152 [abstract; full-text (188K)] (File Cabinet, EB Journal Club)
  • Rodrigue JR, Cornell DL, Howard RJ. Pediatric organ donation: What factors most influence parents' donation decisions? Pediatr Crit Care Med 2008; 9(2):180-185 [abstract] (File Cabinet)
  • Intensivists needed for multiple International Children's Heart Foundation congenital heart surgery trips this year. Read more.... (International Child Health)
  • Koch CG, Li L, Sessler DI, et al. Duration of Red-Cell Storage and Complications after Cardiac Surgery. New Engl J Med 2008; 358:1229-1239. [abstract] (File Cabinet, EB Journal Club)
  • Truog RD. Consent for Organ Donation — Balancing Conflicting Ethical Obligations. New Engl J Med 2008; 358:1209-1211. [full-text] (File Cabinet)

February 2008

  • Hunt EA, Zimmer KP, Rinke ML, Shilkofski NA, Matlin C, Garger C, Dickson C, Miller MR. Transition from a traditional code team to a medical emergency team and categorization of cardiopulmonary arrests in a children's center. Arch Pediatr Adolesc Med. 2008 Feb;162(2):117-22. [abstract] (File Cabinet)
  • Meduri GU, Marik PE, Chrousos GP, Pastores SM, Arlt W, Beishuizen A, Bokhari F, Zaloga G, Annane D. Steroid treatment in ARDS: a critical appraisal of the ARDS network trial and the recent literature. Intensive Care Med. 2008 Jan;34(1):61-9 [abstract] (File Cabinet, EB Journal Club)
  • Numa A, Williams G, Awad J, Duffy B. After-hours admissions are not associated with increased risk-adjusted mortality in pediatric intensive care. Intensive Care Med. 2008 Jan;34(1):148-151. [abstract] (File Cabinet, EB Journal Club)
  • den Brinker M, Hokken-Koelega AC, Hazelzet JA, de Jong FH, Hop WC, Joosten KF.One single dose of etomidate negatively influences adrenocortical performance for at least 24h in children with meningococcal sepsis. Intensive Care Med. 2008 Jan;34(1):163-168 [abstract] (File Cabinet)
  • Tibby SM, Durward A. Interpretation of the echocardiographic pressure gradient across a pulmonary artery band in the setting of a univentricular heart. Intensive Care Med. 2008 Jan;34(1):203-207 [citation] (File Cabinet)
  • Truog RD. Ethical assessment of pediatric research protocols. Intensive Care Med. 2008 Jan;34(1):198-202. [abstract] (File Cabinet)
  • Dr. Greg Hammer at Stanford University is seeking sites interested in participating in a NICHD funded study of the effects of sodium nitroprusside. (Clinical research)
  • Alsaghir AH, Martin CM. Effect of prone positioning in patients with acute respiratory distress syndrome: a meta-analysis. Crit Care Med. 2008 Feb;36(2):603-9. [abstract] (File Cabinet, EB Journal Club)
  • Papers discussed at the Pediatrics Year in Review session at the SCCM Congress in Hawaii are here... (pdf; 100K) (Meetings)
  • Meade MO, Cook Dj, Guyatt GH, et al. for the Lung Open Ventilation Study Investigators. Ventilation Strategy Using Low Tidal Volumes, Recruitment Maneuvers, and High Positive End-Expiratory Pressure for Acute Lung Injury and Acute Respiratory Distress Syndrome: A Randomized Controlled Trial. JAMA 2008;299 637-645 [abstract] (File Cabinet, EB Journal Club)
  • Mercat A, Richard J-C M, Vielle B, et al. for the Expiratory Pressure (Express) Study Group. Positive End-Expiratory Pressure Setting in Adults With Acute Lung Injury and Acute Respiratory Distress Syndrome: A Randomized Controlled Trial. JAMA 2008;299 646-655 [abstract] (File Cabinet, EB Journal Club)
  • Minutes from the 2008 SCCM Pediatric Section Business Meeting are here... (pdf;40K) (Meetings)
  • Heyland DK, Dodek P, Muscedere J, Day A, Cook D; for the Canadian Critical Care Trials Group. Randomized trial of combination versus monotherapy for the empiric treatment of suspected ventilator-associated pneumonia* Crit Care Med 2008; 36:737-744 [abstract] (File Cabinet, EB Journal Club)
  • Becker KL, Snider R, Nylen ES. Procalcitonin assay in systemic inflammation, infection, and sepsis: Clinical utility and limitations Crit Care Med 2008; 36:941-952 [abstract] (File Cabinet)

January 2008

  • Hunt EA, Walker AR, Shafner DH, Miller MR, Pronovost PJ. Simulation of In-Hospital Pediatric Medical Emergencies and Cardiopulmonary Arrests: Highlighting the Importance of the First 5 Minutes. Pediatrics 2008;121 e34-e43 [abstract] (File Cabinet)
  • Sprung CL, Annane D, Keh D, et al., for the CORTICUS Study Group. Hydrocortisone Therapy for Patients with Septic Shock. New Engl J Med 2008; 358:111-124. [abstract] (File Cabinet, EB Journal Club)
  • Brunkhorst FM, Engel C, Bloos F, et al., for the German Competence Network Sepsis (SepNet). Intensive Insulin Therapy and Pentastarch Resuscitation in Severe Sepsis. New Engl J Med 2008; 358:125-139. [abstract] (File Cabinet, EB Journal Club)
  • Meert KL, Eggly S, Pollack M, et al., for the NICHD Collaborative Pediatric Critical Care Research Network. Parents' perspectives on physician-parent communication near the time of a child's death in the pediatric intensive care unit*. Pediatr Crit Care Med 2008; 9:2-7. [abstract; full-text (pdf;160K)] (File Cabinet)
  • Pediatric section meetings at upcoming SCCM Congress are available here... (pdf; 40K) (Meetings)
  • Pandharipande PP, Pun BT, Herr DL, et al. Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial. JAMA. 2007 Dec 12;298(22):2644-53. [abstract] (File Cabinet, EB Journal Club)

December 2007

  • Underwood K, Rubin S, Deakers T, Newth C. Infant Botulism: A 30-Year Experience Spanning the Introduction of Botulism Immune Globulin Intravenous in the Intensive Care Unit at Childrens Hospital Los Angeles. Pediatrics 2007;120 e1380-e1385 [abstract] (File Cabinet)
  • The AAP Section on Critical Care announces: PREP ICU: Critical Care Self-Assessment Program. Review for exams and maintain your knowledge of pediatric critical care with the new self-study program from a source you can trust. Brought to you by the American Academy of Pediatrics' Pediatrics Review and Education Program®, PREP® ICU is an online subspecialty self-assessment program designed to help pediatric intensivists succeed in the PICU. Click here for a FREE trial. (Organizations, Clinical Resources)
  • NiĂ«l-Weise BS, Stijnen T, van den Broek PJ. Anti-infective-treated central venous catheters: a systematic review of randomized controlled trials. Intensive Care Med. 2007 Dec;33(12):2058-68 [abstract] (File Cabinet, EB Journal Club)
  • Michalek J, Svetlikova P, Fedora M, Klimovic M, Klapacova L, Bartosova D, Elbl L, Hrstkova H, Hubacek JA. Bactericidal permeability increasing protein gene variants in children with sepsis. Intensive Care Med. 2007 Dec;33(12):2158-64 [abstract] (File Cabinet)
  • Braner DAV, Lai S, Eman S, Tegtmeyer K. Central Venous Catheterization — Subclavian Vein. New Engl J Med 2007; 357:326 [video] (File Cabinet)
  • Burns JP, Truog RD. Futility: A Concept in Evolution. Chest 2007;132 1987-1993 [abstract](File Cabinet)
  • NACHRI CA-BSI Collaborative - Phase II Announcement is here... (Clinical Resources)
  • The TRIP database (Turning Research Into Practice) now has a special search page for critical care. (EB Resources)
  • Meersseman W, Lagrou K, Maertens J, Wilmer A, Hermans G, Vanderschueren S, Spriet I, Verbeken E, Van Wijngaerden E. Galactomannan in bronchoalveolar lavage fluid: a tool for diagnosing aspergillosis in intensive care unit patients. Am J Respir Crit Care Med. 2008 Jan 1;177(1):27-34 [abstract] (File Cabinet, EB Journal Club)
  • Gajic O, Afessa B, Hanson AC, Krpata T, Yilmaz M, Mohamed SF, Rabatin JT, Evenson LK, Aksamit TR, Peters SG, Hubmayr RD, Wylam ME. Effect of 24-hour mandatory versus on-demand critical care specialist presence on quality of care and family and provider satisfaction in the intensive care unit of a teaching hospital. Crit Care Med. 2008; 36:26-44. [abstract] (File Cabinet, EB Journal Club)
  • Dellinger RP, Levy MM, Carlet JM, et al; for the International Surviving Sepsis Campaign Guidelines Committee. Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med. 2008 Jan;36(1):296-327 [abstract] (File Cabinet)

November 2007

  • European Society of Paediatric and Neonatal Intensive Care (ESPNIC) (Internet Resources)
  • Presentations available for download from the 5th World Congress of Pediatric Critical Care in Geneva, June 25-28, 2007 here.... (Meetings)
  • Zimmerman J. A history of adjunctive glucocorticoid treatment for pediatric sepsis: Moving beyond steroid pulp fiction toward evidence-based medicine. Pediatr Crit Care Med 2007; 8(6):530-539. [abstract; full-text (pdf: 450K)] (File Cabinet)
  • Meert KL, Clark J, Sarnaik AP. Metabolic acidosis as an underlying mechanism of respiratory distress in children with severe acute asthma* Pediatr Crit Care Med. 2007 Nov;8(6):519-523. [abstract] (File Cabinet)
  • Stevens RD, Dowdy DW, Michaels RK, Mendez-Tellez PA, Pronovost PJ, Needham DM. Neuromuscular dysfunction acquired in critical illness: a systematic review. Intensive Care Med. 2007 Nov;33(11):1876-91 [abstract] (File Cabinet, EB Journal Club)
  • Howell MD, Donnino M, Clardy P, Talmor D, Shapiro NI. Occult hypoperfusion and mortality in patients with suspected infection. Intensive Care Med. 2007 Nov;33(11):1892-9 [abstract] (File Cabinet, EB Journal Club)
  • Bontadelli J, Moeller A, Schmugge M, Schraner T, Kretschmar O, Bauersfeld U, Bernet-Buettiker V, Albisetti M. Enoxaparin therapy for arterial thrombosis in infants with congenital heart disease. Intensive Care Med. 2007 Nov;33(11):1978-1984 [abstract] (File Cabinet)
  • The Robert Wood Johnson Clinical Scholars Program. Details here... (Fellowships, Clinical Research)
  • Sharek PJ, Parast LM, Long K, Coombs J, Earnest K, Sullivan J, Frankel LR, Roth SJ. Effect of a Rapid Response Team on Hospital-wide Mortality and Code Rates Outside the ICU in a Children's Hospital. JAMA 2007;298 2267-2274 [abstract] (File Cabinet, EB Journal Club)
  • Lorente L, Lecuona M, Jimenez A, Mora ML, Sierra A. Influence of an Endotracheal Tube with Polyurethane Cuff and Subglottic Drainage on Pneumonia. Am J Respir Crit Care Med. 2007;176 1079-1083 [abstract] (File Cabinet, EB Journal Club)
  • Kreymann KG, de Heer G, Nierhaus Z, Kluge S. Use of polyclonal immunoglobulins as adjunctive therapy for sepsis or septic shock. Crit Care Med 2007; 35:2677-2685 [abstract] (File Cabinet, EB Journal Club)
  • Laupland KB, Kirkpatrick AW, Delaney A. Polyclonal intravenous immunoglobulin for the treatment of severe sepsis and septic shock in critically ill adults: A systematic review and meta-analysis. Crit Care Med 2007; 35:2686-2692 [abstract] (File Cabinet, EB Journal Club)
  • Werdan K, Pilz G, Bujdoso O, et al., for the Score-Based Immunoglobulin Therapy of Sepsis (SBITS) Study Group Score-based immunoglobulin G therapy of patients with sepsis: The SBITS study. Crit Care Med 2007; 35:2693-2701 [abstract] (File Cabinet, EB Journal Club)

October 2007

  • Mazor R, Baden HP. Trends in Pediatric Organ Donation After Cardiac Death. Pediatrics 2007;120 e960-e966 [abstract] (File Cabinet)
  • Dingeman RS, Mitchell EA, Meyer EC, Curley MAQ. Parent Presence During Complex Invasive Procedures and Cardiopulmonary Resuscitation: A Systematic Review of the Literature. Pediatrics 2007;120 842-854 [abstract] (File Cabinet)
  • Su L, Munoz R. Isn't It the Right Time to Address the Impact of Pediatric Cardiac Intensive Care Units on Medical Education? Pediatrics 2007;120 e1117-e1119 [article] (File Cabinet)
  • Shah PS, Ohlsson A, Perlman M. Hypothermia to Treat Neonatal Hypoxic Ischemic Encephalopathy: Systematic Review. Arch Pediatr Adolesc Med 2007;161 951-958 [abstract] (File Cabinet, EB Journal Club)
  • Nadel S, Goldstein B, Williams MD, Dalton H, Peters M, Macias WL, Abd-Allah SA, Levy H, Angle R, Wang D, Sundin DP, Giroir B; REsearching severe Sepsis and Organ dysfunction in children: a gLobal perspective (RESOLVE) study group. Drotrecogin alfa (activated) in children with severe sepsis: a multicentre phase III randomised controlled trial. Lancet. 2007 Mar 10;369(9564):836-43. [abstract] (File Cabinet, EB Journal Club)
  • Villar J, Perez-Mendez L, Lopez J, Belda J, Blanco J, Saralegui I, Suarez-Sipmann F, Lopez J, Lubillo S, Kacmarek RM; on behalf of the HELP Network. An Early PEEP/FIO2 Trial Identifies Different Degrees of Lung Injury in Patients with Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2007 Oct 15;176(8):795-804 [abstract] (File Cabinet, EB Journal Club)
  • Duff JP, Rosychuk RJ, Joffe AR. The safety and efficacy of sustained inflations as a lung recruitment maneuver in pediatric intensive care unit patients. Intensive Care Med. 2007 Oct;33(10):1778-1786. [abstract] (File Cabinet)
  • Hill NS, Brennan J, Garpestad E, Nava S. Noninvasive ventilation in acute respiratory failure. Crit Care Med. 2007; 35(10):2402-2407. [abstract] (File Cabinet)
  • Netzer G, Shah C, Iwashyna T, Lanken P, Finkel B, Fuchs B, Guo W, Christie J. Association of Red Cell Transfusion with Mortality in Patients with Acute Lung Injury. Chest. 2007; 132:1116-1123. [abstract] (File Cabinet, EB Journal Club)
  • Ajizian SJ, Nakagawa TA. Interfacility Transport of the Critically Ill Pediatric Patient. Chest 2007;132 1361-1367 [abstract] (File Cabinet)
  • Kane JM, Rossi J, Tsao S, Burton BK. Metabolic Cardiomyopathy and Mitochondrial Disorders in the Pediatric Intensive Care Unit. J Pediatr 2007; 151:538-541 [full-text link] (Case Reports)

September 2007

  • Corwin HL, Gettinger A, Fabian TC, May A, Pearl RG, Heard S, An R, Bowers PJ, Burton P, Klausner MA, Corwin MJ; EPO Critical Care Trials Group. Efficacy and safety of epoetin alfa in critically ill patients. N Engl J Med. 2007 Sep 6;357(10):965-76. [abstract] (File Cabinet, EB Journal Club)
  • Vassallo P, Trohman RG. Prescribing Amiodarone: An Evidence-Based Review of Clinical Indications. JAMA 2007;298 1312-1322 [abstract] (File Cabinet)
  • Montagnino BA, Ethier AM. The experiences of pediatric nurses caring for children in a persistent vegetative state* Pediatr Crit Care Med. 2007; 8:440-446 [abstract; full-text (pdf 176K)] (File Cabinet)
  • Malhotra A. Low-tidal-volume ventilation in the acute respiratory distress syndrome. N Engl J Med. 2007 Sep 13;357(11):1113-20. [citation] (File Cabinet)
  • Meduri GU, Golden E, Freire AX, Taylor E, Zaman M, Carson SJ, Gibson M, Umberger R. Methylprednisolone infusion in early severe ARDS: results of a randomized controlled trial. Chest. 2007 Apr;131(4):954-63. [abstract] (File Cabinet, EB Journal Club)
  • O'dell E, Tibby SM, Durward A, Murdoch IA. Hyperchloremia is the dominant cause of metabolic acidosis in the postresuscitation phase of pediatric meningococcal sepsis* Crit Care Med. 2007; 35:2390-2394. [abstract] (File Cabinet)

August 2007

  • Kneyber MC, Hersi MI, Twisk JW, Markhorst DG, Plotz FB. Red blood cell transfusion in critically ill children is independently associated with increased mortality. Intensive Care Med. 2007 Aug;33(8):1414-22 [abstract] (File Cabinet, EB Journal Club)
  • Landry M-A, Lafrenaye S, Roy M-C, Cyr C. A Randomized, Controlled Trial of Bedside Versus Conference-Room Case Presentation in a Pediatric Intensive Care Unit. Pediatrics 2007;120 275-280 [abstract] (File Cabinet)
  • Kabrhel C, Thomsen TW, Setnik GS, Walls RM. Orotracheal intubation. N Engl J Med 2007;356:e15 (Web only). (Available at http://content.nejm.org/cgi/content/full/356/17/e15. (File Cabinet)
  • Albuali WH, Singh RN, Fraser DD, Seabrook JA, Kavanagh BP, Parshuram CS, Kornecki A. Have changes in ventilation practice improved outcome in children with acute lung injury? Pediatr Crit Care Med. 2007 Jul;8(4):324-30. [abstract] [full-text (pdf 300K)] (File Cabinet)
  • Wiener RS, Welch HG. Trends in the use of the pulmonary artery catheter in the United States, 1993-2004. JAMA. 2007 Jul 25;298(4):423-9. [abstract] (File Cabinet)
  • Steinbrook R. Organ donation after cardiac death. N Engl J Med. 2007 Jul 19;357(3):209-13 [full-text] (File Cabinet)
  • Ream RS, Mackey K, Leet T, Green MC, Andreone TL, Loftis LL, Lynch RE. Association of nursing workload and unplanned extubations in a pediatric intensive care unit. Pediatr Crit Care Med. 2007 Jul;8(4):366-71 [abstract] (File Cabinet)
  • Rice TW, Wheeler AP, Bernard GR, Hayden DL, Schoenfeld DA, Ware LB; for the National Institutes of Health, National Heart, Lung, and Blood Institute ARDS Network. Comparison of the SpO2/FIO2 Ratio and the PaO2/FIO2 Ratio in Patients With Acute Lung Injury or ARDS. Chest. 2007 Aug;132(2):410-7 [abstract] (File Cabinet)
  • Jones AE, Focht A, Horton JM, Kline JA. Prospective external validation of the clinical effectiveness of an emergency department-based early goal-directed therapy protocol for severe sepsis and septic shock. Chest. 2007 Aug;132(2):425-32 [abstract] (EB Journal Club, File Cabinet)
  • Duffett M, Choong K, Ng V, Randolph A, Cook DJ. Surfactant therapy for acute respiratory failure in children: a systematic review and meta-analysis. Crit Care. 2007 Jun 15;11(3):R66 [abstract] (EB Journal Club, File Cabinet)
  • Casartelli CH, Garcia PC, Branco RG, Piva JP, Einloft PR, Tasker RC. Adrenal response in children with septic shock. Intensive Care Med. 2007 Sep;33(9):1609-13 [abstract] (File Cabinet, EB Journal Club)
  • Rivers EP, Kruse JA, Jacobsen G, Shah K, Loomba M, Otero R, Childs EW. The influence of early hemodynamic optimization on biomarker patterns of severe sepsis and septic shock* Crit Care Med. 2007; 35(9):2016-2024 [abstract] (File Cabinet, EB Journal Club)
  • Quenot JP, Ladoire S, Devoucoux F, Doise JM, Cailliod R, Cunin N, Aube H, Blettery B, Charles PE. Effect of a nurse-implemented sedation protocol on the incidence of ventilator-associated pneumonia* Crit Care Med. 2007; 35(9):2031-2036 [abstract] (File Cabinet, EB Journal Club)
  • Kuzik BA, Al-Qadhi SA, Kent S, Flavin MP, Hopman W, Hotte S, Gander S. Nebulized hypertonic saline in the treatment of viral bronchiolitis in infants. J Pediatr. 2007 Sep;151(3):266-70, 270.e1. [abstract] (File Cabinet, EB Journal Club)
  • The SAFE Study Investigators. Saline or Albumin for Fluid Resuscitation in Patients with Traumatic Brain Injury. New Engl J Med 2007; 357:874-884. [abstract] (File Cabinet, EB Journal Club)
  • Mascia L, Zavala E, Bosma K, Pasero D, Decaroli D, Andrews P, Isnardi D, Davi A, Arguis MJ, Berardino M, Ducati A; on behalf of the Brain IT group. High tidal volume is associated with the development of acute lung injury after severe brain injury: An international observational study. Crit Care Med. 2007 Aug;35(8):1815-1820. [abstract] (File Cabinet, EB Journal Club)
  • Millar KJ, Thiagarajan RR, Laussen PC. Glucocorticoid therapy for hypotension in the cardiac intensive care unit. Pediatr Cardiol. 2007 May-Jun;28(3):176-82 [abstract] (File Cabinet, EB Journal Club)

July 2007


June 2007

  • The AAP Section on Critical Care Spring 2007 newsletter is here... (pdf; 500K) (Organizations)
  • Luce JM, White DB. The Pressure to Withhold or Withdraw Life-sustaining Therapy from Critically Ill Patients in the United States. Am J Respir Crit Care Med. 2007 Jun 1;175(11):1104-8. [abstract] (File Cabinet)
  • Jhung MA, Sunenshine RH, Noble-Wang J, et al. A national outbreak of Ralstonia mannitolilytica associated with use of a contaminated oxygen-delivery device among pediatric patients. Pediatrics. 2007 Jun;119(6):1061-8. [abstract] [accompanying editorial] (File Cabinet)
  • An update on the requirement by the International Committee of Medical Journal Editors to require clinical trial registration prior to enrollment: Laine C, et al. Clinical Trial Registration: Looking Back and Moving Ahead. New Engl J Med 2007; 10.1056/NEJMe078110 [full-text] (Clinical Research)
  • Vilmaz M, Keegan MT, Iscimen R, et al. Toward the prevention of acute lung injury: Protocol-guided limitation of large tidal volume ventilation and inappropriate transfusion. Crit Care Med 2007; 35:1660-1666. [abstract] (File Cabinet, EB Journal Club)
  • Kato Y, Shime N, Hashimoto S, et al. Effects of controlled perioperative antimicrobial prophylaxis on infectious outcomes in pediatric cardiac surgery. Crit Care Med 2007; 35:1763-1768. [abstract] (File Cabinet, EB Journal Club)

May 2007

  • Kain ZN, MacLaren J. P less than .05: what does it really mean? Pediatrics. 2007 Mar;119(3):608-10. [citation (EBM Resources)
  • Mischler M, Fleming GM, Shanley TP, Madden L, Levine J, Castle V, Filipovich AH, Cornell TT. Epstein-Barr Virus-Induced Hemophagocytic Lymphohistiocytosis and X-Linked Lymphoproliferative Disease: A Mimicker of Sepsis in the Pediatric Intensive Care Unit. Pediatrics. 2007; 119:e1212-1218. [abstract] (Case Reports)
  • Lacherade JC, Jabre P, Bastuji-Garin S, Grimaldi D, Fangio P, Theron V, Outin H, De Jonghe B. Failure to achieve glycemic control despite intensive insulin therapy in a medical ICU: incidence and influence on ICU mortality. Intensive Care Med. 2007 May;33(5):814-21 [abstract] (File Cabinet, EB Journal Club)
  • Hatherill M, Salie S, Waggie Z, Lawrenson J, Hewitson J, Reynolds L, Argent A. The lactate:pyruvate ratio following open cardiac surgery in children. Intensive Care Med. 2007 May;33(5):822-829 [abstract] (File Cabinet)
  • Khan H, Belsher J, Yilmaz M, Afessa B, Moore SB, Hubmayr RD, Gajic O. Fresh frozen plasma and platelet transfusions are associated with development of acute lung injury in critically ill medical patients. Chest. 2007; 131:1308-1314. [abstract] (File Cabinet, EB Journal Club)
  • Namachivayam P, Shimizu K, Butt W. Pertussis: Severe clinical presentation in pediatric intensive care and its relation to outcome* Pediatr Crit Care Med. 2007; 8:207-211 [abstract] (File Cabinet)
  • Phipps LM, Bartke CN, Spear DA, Jones LF, Foerster CP, Killian ME, Hughes JR, Hess JC, Johnson DR, Thomas NJ. Assessment of parental presence during bedside pediatric intensive care unit rounds: Effect on duration, teaching, and privacy* Pediatr Crit Care Med. 2007; 8(3):220-224 [abstract] (File Cabinet)
  • Brilli RJ, Gibson R, Luria JW, Wheeler TA, Shaw J, Linam M, Kheir J, McLain P, Lingsch T, Hall-Haering A, McBride M. Implementation of a medical emergency team in a large pediatric teaching hospital prevents respiratory and cardiopulmonary arrests outside the intensive care unit* Pediatr Crit Care Med. 2007; 8(3):236-246 [abstract] [full-text (pdf;1.7M)](File Cabinet)
  • Dyke PC 2nd, Yates AR, Cua CL, Hoffman TM, Hayes J, Feltes TF, Springer MA, Taeed R. Increased calcium supplementation is associated with morbidity and mortality in the infant postoperative cardiac patient*. Pediatr Crit Care Med. 2007 May;8(3):254-7 [abstract] (File Cabinet, EB Journal Club)
  • Varpula M, Pulkki K, Karlsson S, Ruokonen E, Pettila V; FINNSEPSIS Study Group. Predictive value of N-terminal pro-brain natriuretic peptide in severe sepsis and septic shock. Crit Care Med. 2007 May;35(5):1277-83 [abstract] (File Cabinet, EB Journal Club)
  • Graham AS, Ozment C, Tegtmeyer K, Lai S, Braner DAV. Central Venous Catheterization. New Engl J Med 2007; 356:e21 [video] (File Cabinet)
  • Deans KJ, Minneci PC, Suffredini AF, Danner RL, Hoffman WD, Ciu X, Klein HG, Schechter AN, Banks SM, Eichacker PQ, Natanson C. Randomization in clinical trials of titrated therapies: Unintended consequences of using fixed treatment protocols. Crit Care Med. 2007 Jun;35(6):1509-1516 [abstract] (File Cabinet)

April 2007

  • Kumar A, Roberts D, Wood KE, et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med. 2006 Jun;34(6):1589-96. [abstract] (File Cabinet, EB Journal Club)
  • Critical Care Society of Southern Africa (Internet Resources)
  • Klompas M. Does this patient have ventilator-associated pneumonia? JAMA. 2007 Apr 11;297(14):1583-93. [abstract] (File Cabinet)
  • NACHRI and CHCA PICU Catheter-associated Bloodstream infection initiatives make mainstream press: Landro L. Pediatric ICUs Make Headway Against Infection. Wall Street Journal Online. April 18, 2007. [full-text]
  • Lacroix J, Hebert PC, Hutchison, et al. Transfusion Strategies for Patients in Pediatric Intensive Care Units. New Engl J Med 2007; 356:1609-1619. [abstract] (File Cabinet, EB Journal Club)
  • Minutes of the February 2007 SCCM Pediatric Section business meeting are available here...(pdf; 48K)
  • Critical Care Nutrition (Internet Resources, File Cabinet)
  • Winters BD, Pham JC, Hunt EA, Guallar E, Berenholtz S, Pronovost PJ. Rapid response systems: A systematic review. Crit Care Med. 2007 May;35(5):1238-43. [abstract] (File Cabinet)
  • Hoorn EJ, Carlotti AP, Costa LA, MacMahon B, Bohn G, Zietse R, Halperin ML, Bohn D. Preventing a drop in effective plasma osmolality to minimize the likelihood of cerebral edema during treatment of children with diabetic ketoacidosis. J Pediatr. 2007 May;150(5):467-73 [abstract] (File Cabinet, EB Journal Club)

March 2007

  • Nguyen NQ, Chapman MJ, Fraser RJ, Bryant LK, Holloway RH. Erythromycin is more effective than metoclopramide in the treatment of feed intolerance in critical illness. Crit Care Med. 2007 Feb;35(2):483-9. [abstract] (File Cabinet, EB Journal Club)
  • Bass JL, Corwin M, Gozal D, et al. The effect of chronic or intermittent hypoxia on cognition in childhood: a review of the evidence. Pediatrics. 2004 Sep;114(3):805-16. [abstract] (File Cabinet)
  • Scanlon MC, Mistry KP, Jeffries HE. Determining pediatric intensive care unit quality indicators for measuring pediatric intensive care unit safety. Pediatr Crit Care Med 2007; 8[suppl]: S3-S10. [abstract][full-text (pdf;316K)] (File Cabinet)
  • McQuillen PS, Nishimoto MS, Bottrell CL, et al. Regional and central venous oxygen saturation monitoring following pediatric cardiac surgery: Concordance and association with clinical variables. Pediatr Crit Care Med. 2007 Mar;8(2):154-60 [abstract; full-text (pdf 612K)] (File Cabinet)
  • Lipiner D, Sprung CL, Laterre PF, et al. Adrenal function in sepsis: The retrospective Corticus cohort study. Crit Care Med. 2007; 35:1012-1018. [abstract] (File Cabinet, EB Journal Club)
  • Minutes from the PCCM Fellowship Directors' Meeting at SCCM, February, 2007; [Word (80K) or pdf (130K)] (Meetings)

February 2007

  • Jeschke MG, Chinkes DL, Finnerty CC, et al. Blood transfusions are associated with increased risk for development of sepsis in severely burned pediatric patients. Crit Care Med. 2007 Feb;35(2):579-83 [abstract] (File Cabinet, EB Journal Club)
  • Di Filippo S, Lai Y, Manrique A, Pigula F, Munoz R. Intensive care course after stage 1 Norwood procedure: are there early predictors of failure? Intensive Care Med. 2007 Jan;33(1):111-119. [abstract] (File Cabinet)
  • Graham AS, Chandrashekharaiah G, Citak A, Wetzel RC, Newth CJ. Positive end-expiratory pressure and pressure support in peripheral airways obstruction : Work of breathing in intubated children. Intensive Care Med. 2007 Jan;33(1):120-7. [abstract] (File Cabinet)
  • PICU Tools - a Palm OS application for pediatric intensive care practitioners, has been updated to version 5.0: now supports some EBM calculations, several new tools, and a more comprehensive drug and resuscitation database, and has been updated for PALS 2005. Freeware, by M. Verive. Details here... (Software)
  • PedBase+ is a new version of Dr. Alan Gandy's downloadable database of pediatric disorders for PalmOS PDA's. Now with updatable records and other new features. Thanks to Dr. Michael Verive for this version. Available here... (700K). (Software)
  • Hermans G, Wilmer A, Meersseman W, et a l. Impact of intensive insulin therapy on neuromuscular complications and ventilator dependency in the medical intensive care unit. Am J Respir Crit Care Med. 2007 Mar 1;175(5):480-9. [abstract] (File Cabinet, EB Journal Club)
  • Papers discussed at the Pediatrics in Review session at the 2007 SCCM Critical Care Congress are listed here... (pdf; 57K) (Meetings)

January 2007

  • Pronovost P, Needham D, Berenholtz S, et al. An intervention to decrease catheter-related bloodstream infections in the ICU. N Engl J Med. 2006 Dec 28;355(26):2725-32. [abstract] (File Cabinet, EB Journal Club)
  • Truog RD, Christ G, Browning DM, Meyer EC. Sudden traumatic death in children: "we did everything, but your child didn't survive". JAMA. 2006 Jun 14;295(22):2646-54. [abstract] (File Cabinet)
  • Shah PS, Kalyn A, Satodia P,et al. A Randomized, Controlled Trial of Heparin Versus Placebo Infusion to Prolong the Usability of Peripherally Placed Percutaneous Central Venous Catheters (PCVCs) in Neonates: The HIP (Heparin Infusion for PCVC) Study. Pediatrics. 2007 Jan;119(1):e284-91. [abstract] (File Cabinet, EB Journal Club)
  • Durall AL, Laussen PC, Randolph AG. Potential for Donation After Cardiac Death in a Children's Hospital. Pediatrics. 2007 Jan;119(1):e219-24. [abstract] (File Cabinet)
  • Alsoufi B, Bennetts J, Verma S, Caldarone CA. New developments in the treatment of hypoplastic left heart syndrome. Pediatrics. 2007 Jan;119(1):109-17 [abstract] (File Cabinet)
  • New in the AAP Bookstore: Guidelines for Air and Ground Transport of Neonatal and Pediatric Patients - 3rd Edition (Organizations)
  • A list of SCCM Pediatric Section meetings at the upcoming SCCM Congress, February 17-21, 2007 in Orlando, FL, is available here... (pdf; 64K) (Meetings)
  • Osman D, Ridel C, Ray P, et al. Cardiac filling pressures are not appropriate to predict hemodynamic response to volume challenge. Crit Care Med. 2007 Jan;35(1):64-8. [abstract] (File Cabinet)
  • Boyer D, Westra SJ, Kinane TB, Stone JR. A 3-Year-Old Boy with Recurrent Episodes of Respiratory Insufficiency. New Engl J Med 2007; 356:398-407. [full-text for subscribers] (Rare Cases)
  • Sarthi M, Lodha R, Vivekanandhan S, Arora NK. Adrenal status in children with septic shock using low-dose stimulation test. Pediatr Crit Care Med. 2006;8:23-28 [abstract][full-text (pdf;270K)] (File Cabinet, EB Journal Club)
  • Call for abstracts: 2007 AAP National Conference and Exhibition, San Francisco, CA, October 26-30, 2007. Deadline: April 13, 2007. More... (Meetings)

December 2006

  • Meaney PA, Nadkarni VM, Cook EF, et al. for the American Heart Association National Registry of Cardiopulmonary Resuscitation Investigators. Higher Survival Rates Among Younger Patients After Pediatric Intensive Care Unit Cardiac Arrests. Pediatrics 2006;118 2424-2433 [abstract] (File Cabinet, EB Journal Club)
  • American Academy of Pediatrics, American Academy of Pediatric Dentistry, Cote CJ, Wilson S, and the Work Group on Sedation. Guidelines for Monitoring and Management of Pediatric Patients During and After Sedation for Diagnostic and Therapeutic Procedures: An Update. Pediatrics 2006;118 2587-2602 [abstract] (File Cabinet)
  • Silver M, Corwin MJ, Bazan A, Gettinger A, Enny C, Corwin HL. Efficacy of recombinant human erythropoietin in critically ill patients admitted to a long-term acute care facility: a randomized, double-blind, placebo-controlled trial. Crit Care Med. 2006 Sep;34(9):2310-6. [abstract] (File Cabinet, EB Journal Club)
  • The American Academy of Pediatrics' Section on Critical Care is pleased once again to fund a New Investigator Research Award. Read more here... (Organizations)
  • Annane D, Maxime V, Ibrahim F, Alvarez JC, Abe E, Boudou P. Diagnosis of adrenal insufficiency in severe sepsis and septic shock. Am J Respir Crit Care Med. 2006 Dec 15;174(12):1319-26 [abstract] (File Cabinet)
  • Nominations are now being accepted for the 2007 American Academy of Pediatrics Section on Critical Care (SOCC) Distinguished Career Award. More... (Organizations)
  • Canadian Critical Care Trials Group; Heyland D, Dodek P, Muscedere J, Day A. A randomized trial of diagnostic techniques for ventilator-associated pneumonia. N Engl J Med 2006 355(25):2691-3 [abstract] (File Cabinet, EB Journal Club)
  • Angstwurm MW, Engelmann L, Zimmermann T, et al. Selenium in Intensive Care (SIC) study: Results of a prospective randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shock* Crit Care Med. 2007; 35:118-126 [abstract] (File Cabinet, EB Journal Club)
  • Jongerden IP, Rovers MM, Grypdonck MH, Bonten MJ. Open and closed endotracheal suction systems in mechanically ventilated intensive care patients: A meta-analysis. Crit Care Med 2007; 35:260-270. [abstract] (File Cabinet, EB Journal Club)

November 2006

  • A joint resource from the AAP and the AHRQ is available: Pediatric Terrorism and Disaster Preparedness: A Resource for Pediatricians
  • Jones S, Rantell K, Stevens K et al. on behalf of the United Kingdom Pediatric Intensive Care Outcome Study Group. Outcome at 6 Months After Admission for Pediatric Intensive Care: A Report of a National Study of Pediatric Intensive Care Units in the United Kingdom. Pediatrics 2006;118 2101-2108 [abstract] (File Cabinet, EB Journal Club)
  • Program for Maintenance of Certification in Pediatrics update: The Pediatric Critical Care Medicine self-assessment is now available on the ABP Web site
  • Elliott R, McKinley S, Aitken LM, Hendrikz J. The effect of an algorithm-based sedation guideline on the duration of mechanical ventilation in an Australian intensive care unit. Intensive Care Med. 2006 Oct;32(10):1506-14. [abstract] (File Cabinet, EB Journal Club)
  • Lopez-Herce J, Sanchez C, Carrillo A, et al. Transpyloric enteral nutrition in the critically ill child with renal failure. Intensive Care Med. 2006 Oct;32(10):1599-605. [abstract] (File Cabinet)
  • Morris KP, Forsyth RJ, Parslow RC, Tasker RC, Hawley CA; UK Paediatric Traumatic Brain Injury Study Group; Paediatric Intensive Care Society Study Group. Intracranial pressure complicating severe traumatic brain injury in children: monitoring and management. Intensive Care Med. 2006 Oct;32(10):1606-1612. [abstract] (File Cabinet)
  • Carroll CL, Bhandari A, Zucker AR, Schramm CM. Childhood obesity increases duration of therapy during severe asthma exacerbations. Pediatr Crit Care Med. 2006 Nov;7(6):527-531 [abstract; full-text (pdf 320K)] (File Cabinet)
  • Feltes TF, Adatia I. Immunotherapies for acute viral myocarditis in the pediatric patient. Pediatr Crit Care Med. 2006 Nov;7(6 Suppl):S17-S20. [citation] (File Cabinet)
  • Brown RH, Grant PE, Pierson CR. Case 35-2006 - A newborn boy with hypotonia. New Engl J Med 2006; 355:2312-2142. [full-text for subscribers](Case Reports)
  • Silverman HJ, Lemaire F. Ethics and research in critical care. Intensive Care Med. 2006 Nov;32(11):1697-705. [abstract] (File Cabinet)
  • Demoule A, Girou E, Richard JC, Taille S, Brochard L. Benefits and risks of success or failure of noninvasive ventilation. Intensive Care Med. 2006 Nov;32(11):1756-65. [abstract] (File Cabinet, EB Journal Club)
  • Khilnani P, Sarma D, Zimmerman J. Epidemiology and peculiarities of pediatric multiple organ dysfunction syndrome in new delhi, India. Intensive Care Med. 2006 Nov;32(11):1856-62 [abstract] (File Cabinet)
  • Parker CM, Heyland DK, Groll D, Caeser M. Mechanism of injury influences quality of life in survivors of acute respiratory distress syndrome. Intensive Care Med. 2006 Nov;32(11):1895-1900. [abstract] (File Cabinet)
  • Liet JM, Paranon S, Baraton L, Dejode JM, Roze JC. Is a prophylactic treatment by erythropoietin relevant to reduce red blood cell transfusion in the pediatric intensive care unit?*. Pediatr Crit Care Med. 2006 Nov;7(6):541-4. [abstract] (File Cabinet, EB Journal Club)
  • Segers P, Speekenbrink RG, Ubbink DT, van Ogtrop ML, de Mol BA. Prevention of Nosocomial Infection in Cardiac Surgery by Decontamination of the Nasopharynx and Oropharynx With Chlorhexidine Gluconate: A Randomized Controlled Trial. JAMA. 2006 Nov 22;296(20):2460-2466 [abstract] (File Cabinet, EB Journal Club)
  • Lescot T, Degos V, Zouaoui A, Preteux F, Coriat P, Puybasset L. Opposed effects of hypertonic saline on contusions and noncontused brain tissue in patients with severe traumatic brain injury* Crit Care Med. 2006; 34(12):3029-3033 [abstract]

October 2006

  • Tanios MA, Nevins ML, Hendra KP, et al. A randomized, controlled trial of the role of weaning predictors in clinical decision making. Crit Care Med. 2006 Oct;34(10):2530-5 [abstract] (File Cabinet, EB Journal Club)
  • Playfor S, Jenkins I, Boyles C, et al. Consensus guidelines on sedation and analgesia in critically ill children. Intensive Care Med. 2006 Aug;32(8):1125-36 [abstract](File Cabinet)
  • Eichacker PQ, Natanson C, Danner RL. Surviving sepsis--practice guidelines, marketing campaigns, and Eli Lilly. N Engl J Med. 2006 Oct 19;355(16):1640-2. A scathing indictment of commercial interference in societies' guideline development. [full-text for subscribers only]
  • Russell JA. Management of sepsis. N Engl J Med. 2006 Oct 19;355(16):1699-713 [full-text for subscribers only](File Cabinet)
  • Micek ST, Roubinian N, Heuring T, et al. Before-after study of a standardized hospital order set for the management of septic shock. Crit Care Med. 2006; 34(11):2707-2713 [abstract] (File Cabinet, EB Journal Club)
  • Towbin JA, Lowe AM, Colan SD, et al. Incidence, causes, and outcomes of dilated cardiomyopathy in children. JAMA. 2006 Oct 18;296(15):1867-76 [abstract] (File Cabinet)

September 2006

  • Volunteer opportunity in Nepal. Read more... (Opportunities: International Child Health)
  • Shafi NI, Mariscalco MM. Considering the use of induced hypothermia in a pediatric patient with traumatic brain injury: A critical appraisal of two meta-analyses. Pediatr Crit Care Med. 2006 Sep;7(5):468-72 [abstract; full-text (pdf; 140K)] (File Cabinet)
  • Ellenby MS, Tegtmeyer K, Lai S, Vraner DAV. Lumbar Puncture. New Engl J Med 2006; 355:312 [instruction video webpage] (File Cabinet)
  • Taylor RW, O'Brien J, Trottier SJ, et al. Red blood cell transfusions and nosocomial infections in critically ill patients. Crit Care Med. 2006 Sep;34(9):2302-8. [abstract] (File Cabinet, EB Journal Club)

August 2006

  • Van den Berghe G, Wilmer A, Hermans G, et al. Intensive insulin therapy in the medical ICU. N Engl J Med. 2006 Feb 2;354(5):449-61. [abstract] (File Cabinet, EB Journal Club)
  • Who's who in the hospital: a guide to the health care professionals you may meet, from Children's Hospital of San Diego. (Parent Resources)
  • Stephens RC, Fidler K, Wilson P, et al. Endotoxin immunity and the developmentof the systemic inflammatory responsesyndrome in critically ill children. Intensive Care Med. 2006 Feb;32(2):286-294 [abstract] (File Cabinet)
  • Shemie SD, Doig C, Dickens B, et al. Severe brain injury to neurological determination of death: Canadian forum recommendations. Can Med Assoc J 2006;174 S1-S12 [full-text] (File Cabinet)
  • Scolnik D, Coates AL, Stephens D, et al. Controlled Delivery of High vs Low Humidity vs Mist Therapy for Croup in Emergency Departments: A Randomized Controlled Trial. JAMA 2006;295 1274-1280 [abstract] (File Cabinet, EB Journal Club)
  • Cambonie G, Milesi C, Fournier-Favre S, et al. Clinical Effects of Heliox Administration for Acute Bronchiolitis in Young Infants. Chest 2006;129 676-682 [abstract] (File Cabinet, EB Journal Club)
  • Berens RJ, Meyer MT, Mikhailov TA, et al. A Prospective Evaluation of Opioid Weaning in Opioid-Dependent Pediatric Critical Care Patients. Anesth Analg 2006;102 1045-1050 [abstract] (File Cabinet, EB Journal Club)

July 2006

  • Ben-Ari J, Samra Z, Nahum E, Levy I, Ashkenazi S, Schonfeld TM. Oral amphotericin B for the prevention of Candida bloodstream infection in critically ill children. Pediatr Crit Care Med. 2006 Mar;7(2):115-118[abstract; full-text (pdf; 192K)] (File Cabinet, EB Journal Club)
  • Brady AR, Harrison D, Black S, et al. Assessment and Optimization of Mortality Prediction Tools for Admissions to Pediatric Intensive Care in the United Kingdom. Pediatrics. 2006; 117:733-742. [abstract] (File Cabinet)
  • Artinian V, Krayem H, DiGiovine B. Effects of Early Enteral Feeding on the Outcome of Critically Ill Mechanically Ventilated Medical Patients. Chest 2006;129 960-967 [abstract] (File Cabinet, EB Journal Club)
  • Frank M. Access to the Scientific Literature - A Difficult Balance. New Engl J Med 2006; 354:1552-1555. [full-text] (Ideas: Electronic Publishing/Open Access)
  • Tegtmeyer K, Brady G, Lai S, Hodo R, Braner D. Placement of an Arterial Line. New Engl J Med 2006; 354:e13. [free video] (File Cabinet)
  • Villar J, Kacmarek RM, Perez-Mendez L, Aguirre-Jaime A; for the ARIES Network. A high positive end-expiratory pressure, low tidal volume ventilatory strategy improves outcome in persistent acute respiratory distress syndrome: A randomized, controlled trial. Crit Care Med. 2006; 34:1311-1318. [abstract] (File Cabinet, EB Journal Club)
  • Cheng KC, Hou CC, Huang HC, Lin SC, Zhang H. Intravenous injection of methylprednisolone reduces the incidence of postextubation stridor in intensive care unit patients. Crit Care Med. 2006; 34(5):1345-1350. [abstract] (File Cabinet, EB Journal Club)
  • Boyle D, O'connell D, Platt FW, Albert RK. Disclosing errors and adverse events in the intensive care unit. Crit Care Med. 2006; 34(5):1532-1537. [abstract] (File Cabinet)

June 2006

  • Talmor D, Sarge T, O'Donnell CR, Ritz R, Malhotra A, Lisbon A, Loring SH. Esophageal and transpulmonary pressures in acute respiratory failure. Crit Care Med. 2006; 4(5):1389-1394. [abstract] (File Cabinet)
  • Gattinoni L, Caironi P, Cressoni M, et al. Lung Recruitment in Patients with the Acute Respiratory Distress Syndrome. New Engl J Med 2006; 354:1775-1786. [abstract] (File Cabinet)
  • Steinberg KP, Hudson LD, Goodman RB for the Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome. N Engl J Med. 2006 Apr 20;354(16):1671-84 [abstract] (File Cabinet, EB Journal Club)
  • The International Liaison Committee on Resuscitation. The International Liaison Committee on Resuscitation (ILCOR) Consensus on Science With Treatment Recommendations for Pediatric and Neonatal Patients: Pediatric Basic and Advanced Life Support. Pediatrics 2006;117 e955-e977 [abstract] (File Cabinet)
  • American College of Cardiology Foundation/American Heart Association/American College of Physicians, Task Force on Clinical Competence. ACC/AHA/AAP recommendations for training in pediatric cardiology. Pediatrics. 2005; 116:1574-1596. [full-text] Correspondence in response: Baden HP, Zimmerman JJ, Brilli RJ et al. Intensivist-Led Team Approach to Critical Care of Children With Heart Disease. Pediatrics 2006;117 1854-1856 [link] (File Cabinet)
  • Ho KM, Dobb GJ, Webb SA. A comparison of early gastric and post-pyloric feeding in critically ill patients: a meta-analysis. Intensive Care Med. 2006 May;32(5):639-49. [abstract] (File Cabinet, EB Journal Club)
  • Cornejo R, Downey P, Castro R, et al. High-volume hemofiltration as salvage therapy in severe hyperdynamic septic shock. Intensive Care Med. 2006 May;32(5):713-22. [abstract] (File Cabinet)
  • Cua CL, Thiagarajan RR, Gauvreau K, et al. Early postoperative outcomes in a series of infants with hypoplastic left heart syndrome undergoing stage I palliation operation with either modified Blalock-Taussig shunt or right ventricle to pulmonary artery conduit. Pediatr Crit Care Med 2006; 7(3):238-244. [abstract; full-text (pdf;428K)] (File Cabinet, EB Journal Club)
  • Sunrise Children's Hospital Presents the 9th Annual Pediatric Acute Care Symposum "The Pediatric Hospitalist Conference" in Las Vegas, NV June 16-17, 2006 at the Four Seasons Hotel. APLS course offered June 14-15 (limited space). Please go to website for details or registration: www.pedshospitalistsymposium.com. Full brochure is here... (pdf; 1.7MB) (Meetings)
  • CCCATS Library: Critical Assembly Critically Appraised Tpics, from The American Thoracic Society (EB Resources)
  • Statements and Practice Guidelines, from The American Thoracic Society (Guidelines)
  • Lehmann CU, Kim GR, Gujral R, et al. Decreasing errors in pediatric continuous intravenous infusions. Pediatr Crit Care Med. 2006 May;7(3):225-230. [abstract] (File Cabinet)
  • Goldstein B, Nadel S, Peters M, et al. ENHANCE: Results of a global open-label trial of drotrecogin alfa (activated) in children with severe sepsis. Pediatr Crit Care Med. 2006 May;7(3):200-211. [abstract] (File Cabinet)
  • Blume ED, Naftel DC, Bastardi HJ, et al. Outcomes of children bridged to heart transplantation with ventricular assist devices: a multi-institutional study. Circulation. 2006 May 16;113(19):2313-9 [abstract] (File Cabinet)
  • National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. Pulmonary-Artery versus Central Venous Catheter to Guide Treatment of Acute Lung Injury. N Engl J Med. 2006; 354:2213-2224 [abstract] (File Cabinet, EB Journal Club)
  • Moss RL, Dimmitt RA, Barnhart DC, et al. Laparotomy versus peritoneal drainage for necrotizing enterocolitis and perforation. N Engl J Med. 2006 May 25;354(21):2225-34 [abstract] (File Cabinet)
  • Samson RA, Nadkarni VM, Meaney PA, Carey SM, Berg MD, Berg RA; American Heart Association National Registry of CPR Investigators. Outcomes of in-hospital ventricular fibrillation in children. N Engl J Med. 2006 Jun 1;354(22):2328-39. [abstract] (File Cabinet, EB Journal Club)
  • Mancebo J, Fernandez R, Blanch L, et al. A multicenter trial of prolonged prone ventilation in severe acute respiratory distress syndrome. Am J Respir Crit Care Med. 2006 Jun 1;173(11):1233-9. [abstract] (File Cabinet, EB Journal Club)


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