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Evidence Based Journal Reviews

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Date PostedArticle TypeArticle ReviewedLink and Reviewer(s)
435 Review(s) Found
2010-02-08SYSTEMATIC REVIEWKing VJ, Viswanathan M, Bordley WC, et al. Pharmacologic Treatment of Bronchiolitis in Infants and Children: A Systematic Review
Arch Pediatr Adolesc Med 2004 ;158 127-137 [abstract]
Review, by Chloe Johnston MD, Imperial College Healthcare NHS Trust, London, UK
2010-02-05THERAPY/PREVENTIONMarelich GP, Murin S, Battistella F, Inciardi J, Vierra T, Roby M. Protocol Weaning of Mechanical Ventilation in Medical and Surgical Patients by Respiratory Care Practitioners and Nurses : Effect on Weaning Time and Incidence of Ventilator-Associated Pneumonia.
Chest. 2000 ;118(2):459-467. [abstract]
Review, by Julia Mercer Niebauer MD, University of Alabama at Birmingham, AL
2010-02-05THERAPYChoong K, Bohn D, Fraser DD, Gaboury I, Hutchison JS, Joffe AR, Litalien C, Menon K, McNamara P, Ward RE Vasopressin in Pediatric Vasodilatory Shock - A Multi-center Randomized Controlled Trial
Am J Respir Crit Care Med 2009 180:632-639 [abstract]
Review, by Elora Hussain MD and Conrad Epting MD, Children’s Memorial Hospital, Northwestern University, Chicago, IL
2010-01-21SYSTEMATIC REVIEWMcCaffrey J, Farrell C, Whiting P, Dan A, Bagshaw SM, Delaney AP. Corticosteroids to prevent extubation failure: a systematic review and meta-analysis.
Intensive Care Med 2009 Jun;35(6):977-86 [abstract]
Review, by Enrico Opocher MD, University Hospital of Padua, Italy
2010-01-21DIAGNOSTIC TESTSimon L, Saint-Louis P, Amre DK, Lacroix J, Gauvin F. Procalcitonin and C-reactive protein as markers of bacterial infection in critically ill children at onset of systemic inflammatory response syndrome
Pediatr Crit Care Med. 2008 9:407-413 [abstract]
Review, by Konstantine Xoinis MD, University of California, San Francisco
2010-01-05SYSTEMATIC REVIEWAnnane D, Bellissant E, Bollaert PE, Briegel J, Confalonieri M, De Gaudio R, Keh D, Kupfer Y, Oppert M, Merduri GU. Corticosteroids in the Treatment of Severe Sepsis and Septic Shock in Adults: A Systematic Review
JAMA 2009 301:2362-2375. [abstract]
Review, by Lee Tosi MD, Childrens Hospital Los Angeles, Los Angeles CA
2009-12-22THERAPYPayen D, Mateo J, Cavaillon JM, Fraisse F, Floriot C, Vicaut E; Hemofiltration and Sepsis Group of the Collège National de RĂ©animation et de MĂ©decine d Impact of continuous venovenous hemofiltration on organ failure during the early phase of severe sepsis: a randomized controlled trial.
Crit Care Med 2009 Mar;37(3):803-10. [abstract]
Review, by Thomas Conlon MD, University of Pittsburgh/Children's Hospital of Pittsburgh, Pittsburgh PA
2009-12-03PROGNOSISPrice JF, Mott AR, Dickerson HA, Jefferies JL, Nelson DP, Chang AC, O Worsening renal function in children hospitalized with decompensated heart failure: evidence for a pediatric cardiorenal syndrome?
Pediatr Crit Care Med. 2008 9(3):279-84 [abstract]
Review, by Alvaro Orjuela MD, West Virginia University, Morgantown WV
2009-12-03PREDICTION TOOLPost F, Weilemann LS, Messow CM, Sinning C, MĂĽnzel T B-type natriuretic peptide as a marker for sepsis-induced myocardial depression in intensive care patients.
Crit Care Med 2008 36(11):3030-3037 [abstract]
Review, by Pooja Kulkarni MD, Columbia University Medical Center, New York NY
2009-12-03THERAPYRumbak MJ, Newton M, Truncale T, Schwartz SW, Adams JW, Hazard PB. A prospective, randomized, study comparing early percutaneous dilational tracheotomy to prolonged translaryngeal intubation (delayed tracheotomy) in critically ill medical patients
Crit Care Med. 2004 Aug;32(8):1689-94. [abstract]
Review, by Muzamil Noorani MD, Baylor College of Medicine, Houston TX
2009-12-01DIAGNOSISGauvin F, Dassa C, Chaibou M, Proulx F, Farrell CA, Lacroix J. Ventilator-associated pneumonia in intubated children: comparison of different diagnostic methods.
Pediatr Crit Care Med. 2003 Oct;4(4):437-43. [abstract]
Review, by Kathryn Young MD, Medical College of Wisconsin and Children's Hospital of Wisconsin, Milwaukee, WI
2009-12-01PREDICTION TOOLKhemani RG, Bart RD, Alonzo TA, Hatzakis G, Hallam D, Newth CJ. Disseminated intravascular coagulation score is associated with mortality for children with shock
Intensive Care Med 2009 35(2):327-33 [abstract]
Review, by Bill Cutrer MD, Baylor College of Medicine and Texas Children's Hospital, Houston TX
2009-12-01SYSTEMATIC REVIEWMeduri GU, Marik PE, Chrousos GP, Pastores SM, Arlt W, Beishuizen A, Bokhari F, Zaloga G, Annane D. Steroid treatment in ARDS: a critical appraisal of the ARDS network trial and the recent literature.
Intensive Care Med 2008 34(1):61-9 [abstract]
Review, by Bonny Bardhan MD, Tom Spentzas MD, University of Tennessee at Memphis, LeBonheur Children's Hospital, Memphis TN
2009-11-18THERAPYOctober TW, Hardart GE. Successful placement of postpyloric enteral tubes using electromagnetic guidance in critically ill children.
Pediatr Crit Care Med. 2009 10(2):196-200. [abstract]
Review, by Cara Connolly MD, Beaumont Hospital, Dublin, Ireland
2009-11-18THERAPYScolnik D, Coates AL, Stephens D, et al. Controlled Delivery of High vs Low Humidity vs Mist Therapy for Croup in Emergency Departments: A Randomized Controlled Trial.
JAMA 2006 ;295 1274-1280 [abstract]
Review, by Eddie Gordon MD, Baylor College of Medicine, Texas Children's Hospital, Houston TX
2009-10-21PREDICTION TOOLLeteurtre S, Martinot A, Duhamel A, et al. Validation of the paediatric logistic organ dysfunction (PELOD) score: prospective, observational, multicentre study
Lancet. 2003 Jul 19;362(9379):192-7 [abstract]
Review, by J. Davre McNally MD PhD, Children's Hospital of Eastern Ontario, Ottawa, Canada
2009-09-30THERAPYGueugniaud PV, David JS, Chanzy E, et al. Vasopressin and Epinephrine vs. Epinephrine Alone in Cardiopulmonary Resuscitation
N Engl J Med 2008 359:21-30 [abstract]
Review, by Varsha Gharpure MD, Children’s Hospital of Pittsburgh
2009-09-30PROGNOSISMhanna MJ, Zamel YB, Tichy CM, Super DM. The "air leak" test around the endotracheal tube, as a predictor of postextubation stridor, is age dependent in children
Crit Care Med. 2002 ;30(12):2639-43. [abstract]
Review, by Mary G. Gaspers MD, Baylor College of Medicine, Houston TX
2009-09-14THERAPYHall JC, Dobb G, Hall J, de Sousa R, Brennan L, McCauley R. A prospective randomized trial of enteral glutamine in critical illness
Intensive Care Med. 2003 Oct;29(10):1710-6 [abstract]
Review, by Ivie Esangbedo MD, Texas Children's Hospital, Baylor College of Medicine, Houston TX
2009-09-14HARMHoorn EJ, Geary D, Robb M, Halperin ML, Bohn D. Acute Hyponatremia Related to Intravenous Fluid Administration in Hospitalized Children: An Observational Study
Pediatrics 2004 ;113 1279-1284 [abstract]
Review, by Paul Veldhouse MD, Jason Kane MD, Children's Memorial Hospital, Chicago IL
2009-08-16DIAGNOSISLe Monnier A, Carbonnelle E, Zahar JR, Le Bourgeois M, Abachin E, Quesne G, Varon E, Descamps P, De Blic J, Scheinmann P, Berche P, Ferroni A. Microbiological diagnosis of empyema in children: comparative evaluations by culture, polymerase chain reaction, and pneumococcal antigen detection in pleural fluids.
Clin Infect Dis 2006 15;42(8):1135-40 [abstract]
Review, by Stephanie Grayson MD, West Virginia University, Morgantown, WV
2009-07-24META-ANALYSISWan S, Quinlan DJ, Agnelli G, Eikelboom JW. Thrombolysis Compared With Heparin for the Initial Treatment of Pulmonary Embolism: A Meta-Analysis of the Randomized Controlled Trials.
Circulation 2004 ;110 744-749 [abstract]
Review, by Mihaela Damian MD, Stanford University, Lucile Packard Children Hospital, Palo Alto CA
2009-07-16PREDICTION TOOLSeear MD, Scarfe JC, Leblanc JG. Predicting major adverse events after cardiac surgery in children.
Pediatr Crit Care Med. 2008 9:606-611 [abstract]
Review, by Julie D. Sparks PNP-BC, Adrea L. Leach PNP-BC, West Virginia University Hospital, Morgantown, WV
2009-07-13DIAGNOSISKimberly HH, Shah S, Marill K, Noble V. Correlation of optic nerve sheath diameter with direct measurement of intracranial pressure
Acad Emergency Med 2008 15(2):201-4. [abstract]
Review, by Muzamil Noorani MD, Baylor College of Medicine and Texas Children's Hospital, Houston, TX
2009-07-13THERAPYThe NICE-SUGAR Study Investigators. Intensive versus Conventional Glucose Control in Critically Ill Patients
N Engl J Med 2009 360:1283-1297 [abstract]
Review, by Amanda Brooks MD, Northwestern/McGaw Medical Center, Children's Memorial Hospital, Chicago IL
2009-06-30PREDICTION TOOLEsteban A, Alia I, Tobin MJ, et al. Effect of Spontaneous Breathing Trial Duration on Outcome of Attempts to Discontinue Mechanical Ventilation
Am J Respir Crit Care Med 1999 ;159:512-518. [abstract]
Review, by M. Fares Albitar MD, Ikram Haque MD, Shands Hospital at the University of Florida, Gainesville, Florida
2009-06-30PROGNOSISYung D, Widlitz AC, Rosenzweig EB, et al. Outcomes in Children With Idiopathic Pulmonary Arterial Hypertension
Circulation 2004 ;110 660-665 [abstract]
Review, by Christoph Hornik MD, David Turner MD, Duke Children’s Hospital, Durham, North Carolina
2009-06-26PROGNOSISKnoester H, Bronner MB, Bos AP. Surviving pediatric intensive care: physical outcome after 3 months.
Intensive Care Med 2008 34(6):1076-1082 [abstract]
Review, by Simon Li, MD and E. Vincent S. Faustino, MD, Yale University School of Medicine, New Haven, CT
2009-06-03THERAPYGray A, Goodacre S, Newby DE, Masson M, Sampson F, Nicholl J; 3CPO Trialists. Noninvasive ventilation in acute cardiogenic pulmonary edema.
N Engl J Med 2008 359(2):142-51 [abstract]
Review, by Kimberly Baker DO and Michael Wilhelm MD, American Family Children’s Hospital at the University of Wisconsin Hospital and Clinics Madison, WI
2009-05-27THERAPYPapazian L, Gainnier M, Marin V, et al. Comparison of prone positioning and high-frequency oscillatory ventilation in patients with acute respiratory distress syndrome.
Crit Care Med. 2005 Oct;33(10):2162-71. [abstract]
Review, by Jonna Clark MD, Seattle Children's Hospital, Seattle WA
2009-05-25PREDICTION TOOLWratney AT, Benjamin DK Jr, Slonim AD, He J, Hamel DS, Cheifetz IM. The endotracheal tube air leak test does not predict extubation outcome in critically ill pediatric patients.
Pediatr Crit Care Med. 2008 9:490-496 [abstract] [Full-Text]
Review, by Erin Reade MD MPH, Children's Hospital of Philadelphia, Philadelphia PA
2009-04-18THERAPYTalmor D, Sarge T, Malhotra A, O Mechanical Ventilation Guided by Esophageal Pressure in Acute Lung Injury.
N Engl J Med 2008 359:2095-104 [abstract]
Review, by Jane L. Di Gennaro MD, Seattle Children’s Hospital
2009-04-16PREDICTIONVallĂ©e F, Vallet B, Mathe O, Parraguette J, Mari A, Silva S, Samii K, Fourcade O, Genestal M. Central venous-to-arterial carbon dioxide difference: an additional target for goal-directed therapy in septic shock?
Intensive Care Med 2008 34(12):2218-2225 [abstract]
Review, by Fong Lam MD, Baylor College of Medicine and Texas Children's Hospital, Houston TX
2009-04-14THERAPYYañez LJ, Yunge M, Emilfork M, Lapadula M, Alcántara A, Fernández C, Lozano J, Contreras M, Conto L, Arevalo C, Gayan A, Hernández F, Pedraza M, Feddersen M, Bejares M, Morales M, Mallea F, Glasinovic M, Cavada G. A prospective, randomized, controlled trial of noninvasive ventilation in pediatric acute respiratory failure.
Pediatr Crit Care Med. 2008 9(5):484-9 [abstract]
Review, by Zainab Abdurrahman MD MMath, McMaster University, Hamilton, Ontario, Canada
2009-04-06PROGNOSISMarkovitz BP, Goodman DM, Watson RS, Bertoch D, Zimmerman J. A retrospective cohort study of prognostic factors associated with outcome in pediatric severe sepsis: what is the role of steroids?
Pediatr Crit Care Med. 2005 6(3):270-4. [abstract]
Review, by Matthew Borgman MD, Children's Hospital Boston, Boston MA
2009-03-20THERAPYMeade MO, Cook Dj, Guyatt GH, et al. for the Lung Open Ventilation Study Investigators. Ventilation Strategy Using Low Tidal Volumes, Recruitment Maneuvers, and High Positive End-Expiratory Pressure for Acute Lung Injury and Acute Respiratory Distress Syndrome: A Randomized Controlled Trial
JAMA 2008 299 637-645 [abstract]
Review, by Carlos Acuna MD, Antonio Cabrera MD, Le Bonheur Children’s Medical Center, University of Tennessee, Memphis, TN
2009-03-20PROGNOSISKnoester H, Sol JJ, Ramsodit P, et al. Cardiac Function in Pediatric Septic Shock Survivors.
Arch Pediatr Adolesc Med 2008 162:1164-1168 [abstract]
Review, by Simon Li MD, Yale University, New Haven CT
2009-03-20PROGNOSISLĂłpez-Herce J, Santiago MJ, Sánchez C, MencĂ­a S, Carrillo A, Vigil D. Risk factors for gastrointestinal complications in critically ill children with transpyloric enteral nutrition.
Eur J Clin Nutr 2008 62(3):395-400 [abstract]
Review, by Victoria Sheward MB BS, Tanja Adamovic MD, Royal Brompton Hospital, London, UK
2009-02-23THERAPYThe VA/NIH Acute Renal Failure Trial Network. Intensity of Renal Support in Critically Ill Patients with Acute Kidney Injury.
N Engl J Med 2008 359:7-20. [abstract]
Review, by Derek S. Wheeler MD, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
2009-02-17SYSTEMATIC REVIEWDuffett M, Choong K, Ng V, Randolph A, Cook DJ. Surfactant therapy for acute respiratory failure in children: a systematic review and meta-analysis.
Critical Care 2007 15;11(3):R66 [abstract]
Review, by Matei Petrescu MD, Tulane School of Medicine, New Orleans LA
2009-01-22PROGNOSISTamburro RF, Barfield RC, Shaffer ML, Rajasekaran S, Woodard P, Morrison RR, Howard SC, Fiser RT, Schmidt JE, Sillos EM. Changes in outcomes (1996-2004) for pediatric oncology and hematopoietic stem cell transplant patients requiring invasive mechanical ventilation.
Pediatr Crit Care Med. 2008 9(3):270-7. [abstract]
Review, by Christine Vohwinkel MD, Denise Goodman MD, Children’s Memorial Hospital, Northwestern University, Chicago IL
2009-01-15PREDICTION TOOLMillar KJ, Thiagarajan RR, Laussen PC. Glucocorticoid therapy for hypotension in the cardiac intensive care unit.
Pediatr Cardiol 2007 28(3):176-82 [abstract]
Review, by RE Kirsch MD, L Zorzela MD, D Garros MD, University of Alberta, Stollery Children
2009-01-15THERAPYHutchison JS, Ward RE, Lacroix J, et al. for the Hypothermia Pediatric Head Injury Trial Investigators andt the Canadian Critical Care Trials Group. Hypothermia Therapy after Traumatic Brain Injury in Children.
N Engl J Med 2008 358; 2447-2456. [abstract]
Review, by Thomas Arnold MD, University of California San Francisco
2009-01-15THERAPY/PREVENTIONMontañana PA, I Alapont VM, OcĂłn AP, LĂłpez PO, Prats JL, Parreño JD. The use of isotonic fluid as maintenance therapy prevents iatrogenic hyponatremia in pediatrics: A randomized, controlled open study.
Pediatr Crit Care Med. 2008 9(6):589-597 [abstract] [Full-Text]
Review, by Rojjanee Lertbunrian MD, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
2008-12-24PREDICTION TOOLKumar A, Roberts D, Wood KE, et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock.
Crit Care Med 2006 34(6):1589-96 [abstract]
Review, by Thomas Conlon MD, University of Pittsburgh Medical Center/Children’s Hospital of Pittsburgh of UPMC
2008-12-24Technology AssessmentKnirsch W, Kretschmar O, Tomaske M, Stutz K, Nagdyman N, Balmer C, Schmitz A, BĂ©ttex D, Berger F, Bauersfeld U, Weiss M. Cardiac output measurement in children: comparison of the Ultrasound Cardiac Output Monitor with thermodilution cardiac output measurement.
Intensive Care Med 2008 34(6):1060-1064 [abstract]
Review, by Jagdish Ambwani MD, Newark Beth Israel Medical Center, New Jersey
2008-12-11THERAPYMercat A, Richard J-C M, Vielle B, et al. for the Expiratory Pressure (Express) Study Group Positive End-Expiratory Pressure Setting in Adults With Acute Lung Injury and Acute Respiratory Distress Syndrome: A Randomized Controlled Trial.
JAMA 2008 299 646-655 [abstract]
Review, by Aveek Jayant, Postdoctoral student, Dept of Anaesthesiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Medical College PO, Thiruvananthapuram, India
2008-12-08THERAPY/PREVENTIONKollef MH, Afessa B, Anzueto A, et al. for the NASCENT Investigation Group Silver-Coated Endotracheal Tubes and Incidence of Ventilator-Associated Pneumonia: The NASCENT Randomized Trial
JAMA 2008 300(7):805-813 [abstract]
Review, by Guruprasad T. Mahadevaiah MD and Sameer Gupta MD, University of Minnesota Children’s Hospital, Fairview MN
2008-12-01THERAPYHoneycutt TC, El Khashab M, Wardrop RM 3rd, McNeal-Trice K, Honeycutt AL, Christy CG, Mistry K, Harris BD, Meliones JN, Kocis KC. Probiotic administration and the incidence of nosocomial infection in pediatric intensive care: a randomized placebo-controlled trial.
Pediatr Crit Care Med. 2007 8(5):452-8 [abstract]
Review, by Samantha Gee MD, University of Florida College of Medicine, Shand's Children's Hospital, Gainesville FL
2008-11-12PREDICTION TOOLFontela PS, Piva JP, Garcia PC, Bered PL, Zilles K. Risk factors for extubation failure in mechanically ventilated pediatric patients.
Pediatr Crit Care Med. 2005 Mar;6(2):166-170. [abstract]
Review, by Julianne Harrison DO, Myke Federman MD, Mattel Children’s Hospital UCLA, Los Angeles CA
2008-11-10THERAPYParienti JJ, Thirion M, MĂ©garbane B, et al; Members of the Cathedia Study Group. Femoral vs jugular venous catheterization and risk of nosocomial events in adults requiring acute renal replacement therapy: a randomized controlled trial.
JAMA 2008 28;299(20):2413-22. [abstract]
Review, by Srinivas Murthy MD CM, Children's Hospital Boston and Harvard Medical School
2008-11-03SYS-REVIEWKreymann KG, de Heer G, Nierhaus Z, Kluge S. Use of polyclonal immunoglobulins as adjunctive therapy for sepsis or septic shock.
Crit Care Med. 2007 35:2677-2685 [abstract]
Review, by Rahul Bhatia MD, AI duPont Hospital Children, Thomas Jefferson University, Wilmington, DE
2008-10-31THERAPYNava S, Gregoretti C, Fanfulla F, et al. Noninvasive ventilation to prevent respiratory failure after extubation in high-risk patients
Crit Care Med. 2005 Nov;33(11):2465-2470. [abstract]
Review, by Pamela Hilvers MD, Robyn Schultz MD, WVU Children’s Hospital, Morgantown, WV
2008-10-21THERAPYPerkins GD, McAuley DF, Thickett DR, Gao F. The Beta Agonist Lung Injury Trial (BALTI) a randomised placebo controlled clinical trial.
Am J Respir Crit Care Med. 2006 ;173 281-287 [abstract]
Review, by Matei Petrescu, MD, Baylor College of Medicine, Texas Children's Hospital, Houston TX
2008-10-21THERAPYMartin CM, Doig GS, Heyland DK, et al. Multicentre, cluster-randomized clinical trial of algorithms for critical-care enteral and parenteral therapy (ACCEPT)
Can Med Assoc J 2004 ;170 197-204. [abstract]
Review, by Kim Ngo MD, Christopher Babbitt MD, Miller Children's Hospital, Long Beach CA
2008-09-11PROGNOSISJayashree M, Singhi S. Diabetic ketoacidosis: Predictors of outcome in a pediatric intensive care unit of a developing country.
Pediatr Crit Care Med. 2004 Sep;5(5):427-33. [abstract]
Review, by Paul Bauer MD, Medical College of Wisconsin
2008-09-11PREDICTION TOOLTissieres P, da Cruz E, Habre W, Aggoun Y, Mensi N, Kalangos A, Beghetti M. Value of brain natriuretic peptide in the perioperative follow-up of children with valvular disease.
Intensive Care Med 2008 34(6):1109-13 [abstract]
Review, by Jagdish Ambwani MD, Newark Beth Israel Medical Center, New Jersey
2008-09-10PROGNOSISAndreasen JB, Johnsen SP, Ravn HB. Junctional ectopic tachycardia after surgery for congenital heart disease in children.
Intensive Care Med 2008 34(5):895-902 [abstract]
Review, by Joel A. Reyes DO, USAF MC, University of Texas Health Science Center at San Antonio
2008-09-09THERAPYNguyen NQ, Chapman MJ, Fraser RJ, Bryant LK, Holloway RH. Erythromycin is more effective than metoclopramide in the treatment of feed intolerance in critical illness.
Crit Care Med 2007 35(2):483-9. [abstract]
Review, by Erin Reade MD, Children's Hospital of Philadelphia
2008-08-29THERAPYde Oliveira CF, de Oliveira DS, Gottschald AF, Moura JD, Costa GA, Ventura AC, Fernandes JC, Vaz FA, Carcillo JA, Rivers EP, Troster EJ. ACCM/PALS haemodynamic support guidelines for paediatric septic shock: an outcomes comparison with and without monitoring central venous oxygen saturation.
Intensive Care Med 2008 34(6):1065-75 [abstract]
Review, by Robinder G. Khemani MD MsCI, Childrens Hospital Los Angeles, USC Keck School of Medicine
2008-08-29PREDICTION TOOLHuang SC, Wu ET, Chen YS, Chang CI, Chiu IS, Wang SS, Lin FY, Ko WJ. Extracorporeal membrane oxygenation rescue for cardiopulmonary resuscitation in pediatric patients.
Crit Care Med 2008 36(5):1607-13 [abstract]
Review, by Brian Joy MD and Jason M. Kane MD, Northwestern University Feinberg School of Medicine, Children's Memorial Hospital
2008-08-15DIAGNOSTIC TECHNagdyman N, Fleck T, Schubert S, et al. Comparison between cerebral tissue oxygenation index measured by near-infrared spectroscopy and venous jugular bulb saturation in children.
Intensive Care Med. 2005 Jun;31(6):846-50 [abstract]
Review, by Carlos Acuna MD, Antonio Cabrera MD, Le Bonheur Children’s Medical Center, University of Tennessee, Memphis, TN
2008-08-13THERAPYNational Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. Comparison of two fluid-management strategies in acute lung injury
N Engl J Med 2006 354(24):2564-75 [abstract]
Review, by Mary G. Gaspers MD, Baylor College of Medicine, Texas Children's Hospital, Houson TX
2008-08-08THERAPYRussell JA, Walley KR, Singer J, et al. for the VASST Investigators. Vasopressin versus norepinephrine infusion in patients with septic shock
N Engl J Med. 2008 358:877-87 [abstract]
Review, by Samuel Umaru MD, Nicolas Rivera MD, Baylor College of Medicine and Texas Children
2008-07-24PROGNOSISYung M, Wilkins B, Norton L, Slater A, for the Paediatric Study Group; Australian and New Zealand Intensive Care Society. Glucose control, organ failure, and mortality in pediatric intensive care
Pediatr Crit Care Med. 2008 9(2):147-152 [abstract] [Full-Text]
Review, by Sunali Goyal MBBS, Punkaj Gupta MBBS and Natan Noviski MD, Massachusetts General Hospital, Boston MA
2008-07-16THERAPYHonrubia T, Garcia Lopez FJ, et al. Noninvasive vs conventional mechanical ventilation in acute respiratory failure: a multicenter, randomized controlled trial.
Chest. 2005 Dec;128(6):3916-24. [abstract]
Review, by Matei Petrescu MD, Baylor College of Medicine, Texas Children's Hospital, Houston TX
2008-07-16THERAPYPiccinni P, Dan M, Barbacini S, et al. Early isovolaemic haemofiltration in oliguric patients with septic shock.
Intensive Care Med. 2006 Jan;32(1):80-6 [abstract]
Review, by Derek S. Wheeler MD, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
2008-07-16PREDICTIONDyke PC 2nd, Yates AR, Cua CL, Hoffman TM, Hayes J, Feltes TF, Springer MA, Taeed R. Increased calcium supplementation is associated with morbidity and mortality in the infant postoperative cardiac patient
Pediatr Crit Care Med. 2007 8(3):254-7 [abstract]
Review, by David F. Adams MD; Kshitij Mistry MD MSc, Duke Children’s Hospital, Durham NC
2008-07-07PROGNOSISFiser RT, West NK, Bush AJ, Sillos EM, Schmidt JE, Tamburro RF. Outcome of severe sepsis in pediatric oncology patients.
Pediatr Crit Care Med. 2005 Sep;6(5):531-536. [abstract] [Full-Text]
Review, by Danny Castro DO, Baylor College of Medicine, Texas Children
2008-07-07THERAPYBrunkhorst FM, Engel C, Bloos F, et al., for the German Competence Network Sepsis (SepNet). Intensive Insulin Therapy and Pentastarch Resuscitation in Severe Sepsis.
N Engl J Med 2008 358:125-139. [abstract]
Review, by Tara Neumayr MD, Washington University, St. Louis, MO
2008-06-19THERAPYPandharipande PP, Pun BT, Herr DL, et al. Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
JAMA 2007 298(22):2644-53. [abstract]
Review, by Nicolas B Rivera MD, Baylor College of Medicine and Texas Children's Hospital, Houston, TX
2008-06-11THERAPYWerdan K, Pilz G, Bujdoso O, et al., for the Score-Based Immunoglobulin Therapy of Sepsis (SBITS) Study Group Score-based immunoglobulin G therapy of patients with sepsis: The SBITS study.
Crit Care Med. 2007 35:2693-2701 [abstract]
Review, by William Cutrer MD, Baylor College of Medicine, Texas Children's Hospital, Houston TX
2008-06-10THERAPYKuzik BA, Al-Qadhi SA, Kent S, Flavin MP, Hopman W, Hotte S, Gander S. Nebulized hypertonic saline in the treatment of viral bronchiolitis in infants.
J Pediatr. 2007 151(3):266-70, 270.e1 [abstract]
Review, by Shadi Malaeb MD and Scot Bateman MD, University of Massachusetts Medical School
2008-05-31THERAPYSprung CL, Annane D, Keh D, et al., for the CORTICUS Study Group. Hydrocortisone Therapy for Patients with Septic Shock.
N Engl J Med 2008 358:111-124 [abstract]
Review, by Brian C. Bridges MD, Children
2008-05-04ECONOMIC ANALYSISThomas NJ, Hollenbeak CS, Lucking SE, Willson DF. Cost-effectiveness of exogenous surfactant therapy in pediatric patients with acute hypoxemic respiratory failure.
Pediatr Crit Care Med. 2005 Mar;6(2):160-165. [abstract]
Review, by Mahesh Sharman MD, Paula Silva MD, Hurley Medical Center and Michigan State University, Flint, MI
2008-04-30THERAPYNadel S, Goldstein B, Williams MD, Dalton H, Peters M, Macias WL, Abd-Allah SA, Levy H, Angle R, Wang D, Sundin DP, Giroir B REsearching severe Sepsis and Organ dysfunction in children: a gLobal perspective (RESOLVE) study group. Drotrecogin alfa (activated) in children with severe sepsis: a multicentre phase III randomised controlled trial.
Lancet. 2007 369(9564):836-43 [abstract]
Review, by Kimberly Baker MD, American Family Children's Hospital, University of Wisconsin, Madison, WI
2008-04-16THERAPY/PREVENTIONCheng KC, Hou CC, Huang HC, Lin SC, Zhang H. Intravenous injection of methylprednisolone reduces the incidence of postextubation stridor in intensive care unit patients.
Crit Care Med. 2006 ; 34(5):1345-1350. [abstract]
Review, by Julianne Harrison DO, Myke Federman MD, Mattel Children’s Hospital at UCLA, Los Angeles CA
2008-04-16THERAPY/PREVENTIONGarrel D, Patenaude J, Nedelec B, et al. Decreased mortality and infectious morbidity in adult burn patients given enteral glutamine supplements: A prospective, controlled, randomized clinical trial.
Crit Care Med. 2003 Oct;31(10):2444-9. [abstract]
Review, by Jama Sy MD, Texas Children's Hospital and Baylor College of Medicine, Houston TX
2008-04-16PROGNOSISCasartelli CH, Garcia PC, Branco RG, Piva JP, Einloft PR, Tasker RC. Adrenal response in children with septic shock.
Intensive Care Med 2007 33(9):1609-13 [abstract]
Review, by Penelope Sandiford MD, Children’s Hospital of Michigan, Detroit MI
2008-04-05HARMKhan H, Belsher J, Yilmaz M, Afessa B, Moore SB, Hubmayr RD, Gajic O. Fresh frozen plasma and platelet transfusions are associated with development of acute lung injury in critically ill medical patients.
Chest 2007 131:1308-1314 [abstract]
Review, by Robert A. Niebler MD, Medical College of Wisconsin, Milwaukee, WI
2008-04-03META-ANALYSISZurcher M, Tramer MR, Walder B. Colonization and Bloodstream Infection with Single- Versus Multi-Lumen Central Venous Catheters: A Quantitative Systematic Review
Anesth Analg 2004 ;99 177-182. [abstract]
Review, by by John S Giuliano Jr MD, Derek S Wheeler MD, Cincinnati Children’s Medical Center, Cincinnati OH
2008-04-03THERAPYThe SAFE Study Investigators Saline or Albumin for Fluid Resuscitation in Patients with Traumatic Brain Injury.
N Engl J Med. 2007 357:874-884 [abstract]
Review, by Nicolas Rivera MD and M Michelle Mariscalco MD, Baylor College of Medicine and Texas Children’s Hospital, Houston, TX
2008-04-03PREDICTION TOOLHowell MD, Donnino M, Clardy P, Talmor D, Shapiro NI. Occult hypoperfusion and mortality in patients with suspected infection.
Intensive Care Med 2007 33(11):1892-9 [abstract]
Review, by Sunali Goyal MBBS (SERI), Punkaj Gupta, MBBS (MGH), Harvard Medical School, Boston
2008-04-03THERAPYSharek PJ, Parast LM, Long K, Coombs J, Earnest K, Sullivan J, Frankel LR, Roth SJ. Effect of a Rapid Response Team on Hospital-wide Mortality and Code Rates Outside the ICU in a Children
JAMA 2007 298 2267-2274 [abstract]
Review, by Jennifer Plant MD, University of California San Francisco and Children’s Hospital and Research Center Oakland
2008-03-04THERAPYMeduri GU, Golden E, Freire AX, Taylor E, Zaman M, Carson SJ, Gibson M, Umberger R. Methylprednisolone infusion in early severe ARDS: results of a randomized controlled trial.
Chest 2007 131(4):954-63. [abstract]
Review, by Jennifer R Foster MD FRCPC, Children’s Hospital of Eastern Ontario
2008-02-06SYSTEMATIC REVIEWSafdar N, Said A, Gangnon RE, Maki DG. Risk of Hemolytic Uremic Syndrome After Antibiotic Treatment of Escherichia coli O157:H7 Enteritis. A Meta-analysis
JAMA 2002 ; 288:996-1001. [abstract]
Review, by Jama Sy MD, Texas Children
2008-01-31PREDICTION TOOLFlori HR, Glidden DV, Rutherford GW, Matthay MA. Pediatric Acute Lung Injury: Prospective Evaluation of Risk Factors Associated with Mortality
Am J Respir Crit Care Med. 2005 171(9):995-1001 [abstract]
Review, by Jeffrey J. Fanning MD, Medical College of Wisconsin, Milwaukee, WI
2008-01-31THERAPYMartin GS, Moss M, Wheeler AP, Mealer M, Morris JA, Bernard GR. A randomized, controlled trial of furosemide with or without albumin in hypoproteinemic patients with acute lung injury.
Crit Care Med. 2005 Aug;33(8):1681-1687. [abstract]
Review, by Robert B. Kelly MD, Irwin K. Weiss MD, Mattel Children’s Hospital at UCLA, Los Angeles, CA
2008-01-21META-ANALYSISSackner-Bernstein JD, Kowalski M, Fox M, Aaronson K. Short-term risk of death after treatment with nesiritide for decompensated heart failure: a pooled analysis of randomized controlled trials.
JAMA. 2005 Apr 20;293(15):1900-5. [abstract]
Review, by Anne Marie Yered MD, Children's Hospital of Michigan, Detroit MI
2008-01-21PREDICTION TOOLRobinson LR, Micklesen PJ, Tirschwell DL, Lew HL. Predictive value of somatosensory evoked potentials for awakening from coma
Crit Care Med. 2003 Mar;31(3):960-7. [abstract]
Review, by Nadeem Shafi MD, University of Florida, Gainesville FL
2007-12-26HARMKneyber MC, Hersi MI, Twisk JW, Markhorst DG, Plotz FB. Red blood cell transfusion in critically ill children is independently associated with increased mortality
Intensive Care Med 2007 33(8):1414-22 [abstract]
Review, by LM Zorzela MD, R Kirsh MD, G Guerra MD, AR Joffe MD; Stollery Children
2007-12-18THERAPYHoudijk AP, Rijnsburger ER, Jansen J, et al. Randomised trial of glutamine-enriched enteral nutrition on infectious morbidity in patients with multiple trauma
Lancet. 1998 5;352(9130):772-6. [abstract]
Review, by Jama Sy MD, Texas Children's Hospital and Baylor College of Medicine, Houston TX
2007-12-18THERAPYLacroix J, Hebert PC, Hutchison, et al. Transfusion Strategies for Patients in Pediatric Intensive Care Units
N Engl J Med 2007 356:1609-1619 [abstract]
Review, by Eloa S Adams MD, Lucile Packard Children's Hospital, Stanford University School of Medicine, Palo Alto, CA
2007-12-14THERAPYBerens RJ, Meyer MT, Mikhailov TA, et al. A Prospective Evaluation of Opioid Weaning in Opioid-Dependent Pediatric Critical Care Patients.
Anesth Analg 2006 ;102 1045-1050 [abstract]
Review, by Katherine M Pleacher MD, Susan L Bratton MD MPH, University of Utah, Salt Lake City, UT
2007-12-14THERAPYFineman LD, LaBrecque M, Shih M-C, Curley MA Prone positioning can be safely performed in critically ill infants and children
Pediatr Crit Care Med. 2006 7: 413-22 [abstract]
Review, by Mark D Weber RN PCCNP, Duke University Medical Center, Durham, NC
2007-12-13PROGNOSISHenzler D, Cooper DJ, Tremayne AB, Rossaint R, Higgins A. Early modifiable factors associated with fatal outcome in patients with severe traumatic brain injury: a case control study.
Crit Care Med 2007 35(4):1027-31 [abstract]
Review, by S. David McSwain MD MPH, Duke University Medical Center, Durham NC
2007-11-28PREDICTION TOOLLawrence SE, Cummings EA, Gaboury I, Daneman D. Population-based study of incidence and risk factors for cerebral edema in pediatric diabetic ketoacidosis.
J Pediatr. 2005 May;146(5):688-92. [abstract]
Review, by Girish Deshpande MD, Adelberto Torres MD, University of Illinois, Peoria IL
2007-11-17THERAPYFerrer M, Valencia M, Nicolas JM, Bernadich O, Badia JR, Torres A. Early noninvasive ventilation averts extubation failure in patients at risk: a randomized trial
Am J Respir Crit Care Med. 2006 Jan 15;173(2):164-70. [abstract]
Review, by Punkaj Gupta MD, Natan Noviski MD, Massachusetts General Hospital, Boston MA
2007-11-17PROGNOSISJones S, Rantell K, Stevens K et al. on behalf of the United Kingdom Pediatric Intensive Care Outcome Study Group. Outcome at 6 Months After Admission for Pediatric Intensive Care: A Report of a National Study of Pediatric Intensive Care Units in the United Kingdom.
Pediatrics 2006 118 2101-2108 [abstract]
Review, by Katri Typpo MD MPH, Baylor College of Medicine, Texas Children
2007-11-17PREDICTION TOOLJeschke MG, Chinkes DL, Finnerty CC, et al. Blood transfusions are associated with increased risk for development of sepsis in severely burned pediatric patients.
Crit Care Med 2007 35(2):579-83 [abstract]
Review, by Kathryn Young MD, Medical College of Wisconsin, Children
2007-10-12HARMHoorn EJ, Carlotti AP, Costa LA, MacMahon B, Bohn G, Zietse R, Halperin ML, Bohn D. Preventing a drop in effective plasma osmolality to minimize the likelihood of cerebral edema during treatment of children with diabetic ketoacidosis.
J Pediatr 2007 150(5):467-73 [abstract]
Review, by Robert B. Kelly MD and Andranik Madikians, MD, Mattel Children’s Hospital at UCLA, Los Angeles, CA
2007-10-06PROGNOSISSarthi M, Lodha R, Vivekanandhan S, Arora NK. Adrenal status in children with septic shock using low-dose stimulation test
Pediatr Crit Care Med. 2007 8:23-28. [abstract] [Full-Text]
Review, by G Garcia Guerra MD, L Zorzela MD, R Kirsch MD, Stollery Children
2007-10-06SYSTEMATIC REVIEWVillatoro E, Bassi C, Larvin M. Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis.
Cochrane Review 2006 (4):CD002941 [abstract]
Review, by Edwin Taylor MD, West Virginia University, Morgantown, WV
2007-10-02PROGNOSISCremer OL, van Dijk GW, van Wensen E, Brekelmans GJ, Moons KG, Leenen LP, Kalkman CJ. Effect of intracranial pressure monitoring and targeted intensive care on functional outcome after severe head injury.
Crit Care Med. 2005 Oct;33(10):2207-2213. [abstract]
Review, by Meredith Bone MD, Children’s Memorial Hospital, Northwestern University, Chicago, IL
2007-09-19THERAPYWiedermann CJ, Hoffmann JN, et al.; for the KyberSept Investigators. High-dose antithrombin III in the treatment of severe sepsis in patients with a high risk of death: Efficacy and safety.
Crit Care Med. 2006 Feb;34(2):285-292. [abstract]
Review, by Nicolas Rivera MD and Mona McPherson MD, Baylor College of Medicine and Texas Children
2007-09-10PROGNOSISLiet JM, Paranon S, Baraton L, Dejode JM, Roze JC. Is a prophylactic treatment by erythropoietin relevant to reduce red blood cell transfusion in the pediatric intensive care unit?
Pediatric Critical Care Medicine 2006 7(6):541-4. [abstract]
Review, by Joel A. Reyes DO, US Air Force and Texas Children’s Hospital/Baylor College of Medicine
2007-08-23THERAPYHuang CJ, Lin HC. Association between adrenal insufficiency and ventilator weaning.
Am J Respir Crit Care Med. 2006 Feb 1;173(3):276-80. [abstract]
Review, by Christine Agee, CPNP-AC/PC, Duke University Medical Center, Durham, NC
2007-08-18DIAGNOSISRey C, Los Arcos M, Concha A, et al. Procalcitonin and C-reactive protein as markers of systemic inflammatory response syndrome severity in critically ill children.
Intensive Care Med 2007 33(3):477-84 [abstract]
Review, by Punkaj Gupta MD, Massachusetts General Hospital, Boston MA
2007-08-14THERAPYMayer SA, Brun NC, Begtrup K, Broderick J, Davis S, Diringer MN, Skolnick BE, Steiner T; Recombinant Activated Factor VII Intracerebral Hemorrhage Trial Investigators. Recombinant activated factor VII for acute intracerebral hemorrhage.
N Engl J Med. 2005 Feb 24;352(8):777-85 [abstract]
Review, by Vikas Shah MD, Cornell University, New York, NY
2007-07-20DIAGNOSISRey C, Los Arcos M, Concha A, et al. Procalcitonin and C-reactive protein as markers of systemic inflammatory response syndrome severity in critically ill children.
Intensive Care Med 2007 33(3):477-84 [abstract]
Review, by S. David McSwain MD, Duke University, Durham NC
2007-07-06THERAPYUmpierrez GE, Cuervo R, Karabell A, Latif K, Freire AX, Kitabchi AE Treatment of diabetic ketoacidosis with subcutaneous insulin aspart.
Diabetes Care 2004 27(8):1873-8 [abstract]
Review, by Brian Ely MD, Satid Thammasitboon, MD MHPE, West Virginia University, Morgantown WV
2007-06-21THERAPYAngstwurm MW, Engelmann L, Zimmermann T, et al. Selenium in Intensive Care (SIC) study: Results of a prospective randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shock
Crit Care Med 2007 35:118-126 [abstract]
Review, by Marvin Mata MD, Kathleen Meert MD, Children
2007-06-20SYSTEMATIC REVIEWMarik P. Low-dose dopamine: a systematic review.
Intensive Care Med 2002 ; 28: 877-883. [abstract]
Review, by Shira J. Gertz MD, Texas Children's Hospital and Baylor College of Medicine, Houston TX
2007-06-08PROGNOSISSamson RA, Nadkarni VM, Meaney PA, Carey SM, Berg MD, Berg RA; American Heart Association National Registry of CPR Investigators. Outcomes of in-hospital ventricular fibrillation in children
N Engl J Med 2006 354(22):2328-39 [abstract]
Review, by Downing Lu MD, Children
2007-05-19THERAPYKoeman M, van der Ven AJ, Hak E, et al. Oral Decontamination with Chlorhexidine Reduces the Incidence of Ventilator-associated Pneumonia.
Am J Respir Crit Care Med. 2006 173(12):1348-5 [abstract]
Review, by Kelby G. Maher DO, Scot T. Bateman MD, University of Massachusetts Medical Center, Worcester, MA
2007-05-19DIAGNOSISVarpula M, Karlsson S, Ruokonen E, Pettila V. Mixed venous oxygen saturation cannot be estimated by central venous oxygen saturation in septic shock.
Intensive Care Med 2006 32(9):1336-43 [abstract]
Review, by Reviewed by Gökhan Kalkan MD, University of California San Francisco
2007-05-15PROGNOSISWintergerst KA, Buckingham B, Gandrud L, et al. Association of hypoglycemia, hyperglycemia, and glucose variability with morbidity and death in the pediatric intensive care unit
Pediatrics 2006 118(1):173-9 [abstract]
Review, by Shira Gertz MD, Texas Children
2007-05-02PROGNOSISMeaney PA, Nadkarni VM, Cook EF, et al. for the American Heart Association National Registry of Cardiopulmonary Resuscitation Investigators. Higher Survival Rates Among Younger Patients After Pediatric Intensive Care Unit Cardiac Arrests.
Pediatrics 2006 118:2424-2433 [abstract]
Review, by Jennifer Matchey MD, Medical College of Wisconsin, Children
2007-04-24SYSTEMATIC REVIEWSimpson F, Doig GS. Parenteral vs. enteral nutrition in the critically ill patient: a meta-analysis of trials using the intention to treat principle
Intensive Care Med. 2005 Jan;31(1):12-23 [abstract]
Review, by Autumn M. Richards MD, Kevin M. Creamer MD, Walter Reed Army Medical Center, Washington, D.C. (1)
2007-03-09PREDICTION TOOLChavez A, Cruz RD, Zaritsky A. Spontaneous breathing trial predicts successful extubation in infants and children
Pediatric Critical Care Medicine 2006 7(4):324-8 [abstract] [Full-Text]
Review, by Karl Yen MD, Children
2007-02-23THERAPYMancebo J, Fernandez R, Blanch L, et al. A multicenter trial of prolonged prone ventilation in severe acute respiratory distress syndrome.
Am J Respir Crit Care Med. 2006 173(11):1233-9. [abstract]
Review, by Moreshwar S. Desai MD, Pediatric Critical Care, Baylor College of Medicine, Houston, TX
2006-12-19SYSTEMATIC REVIEWFriedrich JO, Adhikari N, Herridge MS, Beyene J. Meta-analysis: low-dose dopamine increases urine output but does not prevent renal dysfunction or death.
Ann Intern Med. 2005 Apr 5;142(7):510-24 [abstract]
Review, by Omer Mansoor MD, West Virginia University, Morgantown, WV
2006-12-19THERAPYCua CL, Thiagarajan RR, Gauvreau K, et al. Early postoperative outcomes in a series of infants with hypoplastic left heart syndrome undergoing stage I palliation operation with either modified Blalock-Taussig shunt or right ventricle to pulmonary artery conduit.
Pediatric Critical Care Medicine 2006 7(3):238-44 [abstract]
Review, by Angela Aramburo MD, University of California San Francisco
2006-12-16SYSTEMATIC REVIEWDavison C, Ventre KM, Luchetti M, Randolph AG. Efficacy of interventions for bronchiolitis in critically ill infants: A systematic review and meta-analysis.
Pediatr Crit Care Med. 2004 Sep;5(5):482-489. [abstract]
Review, by Omer Mansoor MD, West Virginia University, Morgantown, WV
2006-11-29THERAPYInhaled Nitric Oxide Study Group. Inhaled Nitric Oxide and Persistent Pulmonary Hypertension of the Newborn.
N Engl J Med 1997 ; 336: 605-610. [abstract]
Review, by Jessica Oldfield, MBChB MRCPCH, Leeds General Infirmary, LEEDS, United Kingdom
2006-10-19HARMMarcin JP, Rutan E, Rapetti PM, Brown JP, Rahnamayi R, Pretzlaff RK. Nurse staffing and unplanned extubation in the pediatric intensive care unit.
Pediatr Crit Care Med. 2005 May;6(3):254-257. [abstract]
Review, by Corey Philpot MD, Medical College of Wisconsin and Children's Hospital of Wisconsin, Milwaukee, WI
2006-10-10PREDICTION TOOLAlberti C, Brun-Buisson C, Chevret S, et al. for the European Sepsis Study Group. Systemic Inflammatory Response and Progression to Severe Sepsis in Critically Ill Infected Patients.
Am J Respir Crit Care Med 2005 ;171 461-468 [abstract]
Review, by by Angela Czaja MD, Seattle Children's Hospital and Regional Medical Center, Seattle, WA
2006-10-02SURROGATE END POINTCambonie G, Milesi C, Fournier-Favre S, et al. Clinical Effects of Heliox Administration for Acute Bronchiolitis in Young Infants
Chest 2006 ;129 676-682 [abstract]
Review, by Robert Niebler MD, Children
2006-10-02PREDICTION TOOLDurward A, Tibby SM, Skellett S, Austin C, Anderson D, Murdoch IA. The strong ion gap predicts mortality in children following cardiopulmonary bypass surgery.
Pediatr Crit Care Med. 2005 May;6(3):281-285 [abstract]
Review, by Asumthia S Jeyapalan DO, Texas Children's Hospital, Baylor College of Medicine, Houston, TX
2006-10-02THERAPYSchulze-Neick I, Hartenstein P, Li J, et al. Intravenous sildenafil is a potent pulmonary vasodilator in children with congenital heart disease.
Circulation. 2003 Sep 9;108 Suppl 1:II167-73. [abstract]
Review, by Jai Udassi MD FAAP, Ikram Haque MD FAAP, Shands Children's Hospital, University of Florida, College of Medicine, Gainesville, FL
2006-09-28THERAPYKrueger WA, Lenhart FP, Neeser G et al. Influence of Combined Intravenous and Topical Antibiotic Prophylaxis on the Incidence of Infections, Organ Dysfunctions, and Mortality in Critically Ill Surgical Patients: A Prospective, Stratified, Randomized, Double-Blind, Placebo-controlled Clinica
Am J Respir Crit Care Med 2002 ;166 1029-1037 [abstract]
Review, by Luna Sharma MD, West Virginia University
2006-09-24THERAPYNational Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. Pulmonary-Artery versus Central Venous Catheter to Guide Treatment of Acute Lung Injury.
N Engl J Med 2006 354:2213-2224 [abstract]
Review, by Pallavi Patwari MD, Children's Memorial Hospital, Chicago, IL
2006-09-22THERAPYde La Cal MA, Cerda E, Garcia-Hierro P, van Saene HK, Gomez-Santos D, Negro E, Lorente JA. Survival benefit in critically ill burned patients receiving selective decontamination of the digestive tract: a randomized, placebo-controlled, double-blind trial.
Ann Surg. 2005 241(3):424-30 [abstract]
Review, by H Rowlands MD, Birmingham Childrens Hospital, Birmingham UK
2006-09-10THERAPYVan den Berghe G, Wilmer A, Hermans G, et al. Intensive insulin therapy in the medical ICU.
N Engl J Med 2006 354(5):449-61 [abstract]
Review, by Kourosh Parsapour, MD and James P. Marcin, MD, MPH, UC Davis Childrens Hospital
2006-09-10SYSTEMATIC REVIEWFaustino EV, Apkon M. Persistent hyperglycemia in critically ill children.
J Pediatr 2005 146(1):30-4 [abstract]
Review, by Michele Kong, MD University of Birmingham at Alabama, AL
2006-09-08THERAPYGarland JS, Alex CP, Henrickson KJ, McAuliffe TL, Maki DG. A vancomycin-heparin lock solution for prevention of nosocomial bloodstream infection in critically ill neonates with peripherally inserted central venous catheters: a prospective, randomized trial.
Pediatrics 2005 116(2):e198-205
Review, by Mary G. Gaspers, MD, Baylor College of Medicine, Texas Childrens Hospital
2006-05-24THERAPYBertolini G, Iapichino G, Radrizzani D, et al. Early enteral immunonutrition in patients with severe sepsis: Results of an interim analysis of a randomized multicentre clinical trial.
Intensive Care Med 2003 29: 834-840. [abstract]
Review, by J Kane MD, Medical College Wisconsin, Milwaukee, WI
2006-05-23PROGNOSISHerridge MS, Cheung AM, Tansey CM, et al. One-year outcomes in survivors of the acute respiratory distress syndrome.
N Engl J Med 2003 Feb 20;348(8):683-93 [abstract]
Review, by G Wolf
2006-05-21DIAGNOSTIC TESTMilling TJ Jr, Rose J, Briggs WM, Birkhahn R, Gaeta TJ, Bove JJ, Melniker LA. Randomized, controlled clinical trial of point-of-care limited ultrasonography assistance of central venous cannulation: The Third Sonography Outcomes Assessment Program (SOAP-3) Trial.
Crit Care Med 2005 171:348-353 [abstract]
Review, by Matthew Christopherson MB ChB MRCPCH, Leeds General Infirmary, UK
2006-05-18PROGNOSISCohan P, Wang C, McArthur DL, et al. Acute secondary adrenal insufficiency after traumatic brain injury: A prospective study.
Crit Care Med 2005 Oct;33(10):2358-2366 [abstract]
Review, by A Hoogerland
2006-05-16PREDICTIONGraciano AL, Balko JA, Rahn DS, Ahmad N, Giroir BP. The Pediatric Multiple Organ Dysfunction Score (P-MODS): Development and validation of an objective scale to measure the severity of multiple organ dysfunction in critically ill children.
Crit Care Med 2005 Jul;33(7):1484-1491 [abstract]
Review, by K Hebbar, T Petrillo
2006-04-27THERAPYMorelli A, Ricci Z, Bellomo R, et al. Prophylactic fenoldopam for renal protection in sepsis: a randomized, double-blind, placebo-controlled pilot trial.
Crit Care Med 2005 Nov;33(11):2451-6 [abstract]
Review, by S Wu
2006-04-03THERAPYOppert M, Schindler R, Husung C, et al., Low-dose hydrocortisone improves shock reversal and reduces cytokine levels in early hyperdynamic septic shock
Crit Care Med 2005 Nov;33(11):2457-64 [abstract]
Review, by S van Schaik
2006-04-02PREDICTION TOOLTrachsel D, McCrindle BW, Nakagawa S, Bohn DJ, Oxygenation Index Predicts Outcome in Children with Acute Hypoxemic Respiratory Failure
Am J Respir Crit Care Me 2005 172:206-211 [abstract]
Review, by C Froehlich J Fortenberry
2006-03-25PREDICTION TOOLLeclerc F, Leteurtre S, Duhamel A, et al., Cumulative Influence of Organ Dysfunctions and Septic State on Mortality of Critically Ill Children
Am J Respir Crit Care Me 2005 171:348-353 [abstract]
Review, by K Typpo
2006-03-18PREDICTION TOOLThiagarajan RR, Bratton SL, Martin LD, et al., Predictors of Successful Extubation in Children
Am J Respir Crit Care Me 1999 160:1562-1566 [abstract]
Review, by K Yen
2006-03-11PREDICTION TOOLCohen S, Springer C, Avital A, et al., Amino-Terminal Pro-Brain-Type Natriuretic Peptide: Heart or Lung Disease in Pediatric Respiratory Distress?
Pediatrics 2005 115 1347-1350 [abstract]
Review, by R Srinivasan
2006-03-08THERAPYGuerin C, Gaillard S, Lemasson S, et al., Effects of Systematic Prone Positioning in Hypoxemic Acute Respiratory Failure: A Randomized Controlled Trial
JAMA 2004 292 2379-2387 [abstract]
Review, by AS Jeyapalan
2006-02-24THERAPYRaoof S, Chowdhrey N, Raoof S, et al., Effect of Combined Kinetic Therapy and Percussion Therapy on the Resolution of Atelectasis in Critically Ill Patients
Chest 1999 115:1658-1666 [abstract]
Review, by O Borisenko
2006-01-27SYSTEMATIC REVIEWShah MR, Hasselblad V, Stevenson LW, Binanay C, O'Connor CM, Sopko G, Califf RM. Impact of the pulmonary artery catheter in critically ill patients: meta-analysis of randomized clinical trials.
JAMA 2005 Oct 5;294(13):1664-70 [abstract]
Review, by S Gertz
2006-01-26SYSTEMATIC REVIEWPeter JV, Moran JL, Phillips-Hughes J., , A metaanalysis of treatment outcomes of early enteral versus early parenteral nutrition in hospitalized patients.
Crit Care Med 2005 Jan;33(1):213-20 [abstract]
Review, by M Desai
2006-01-23THERAPYShankaran S, Laptook AR, Ehrenkranz RA, et al., Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy.
N Engl J Med 2005 Oct 13;353(15):1574-84 [abstract]
Review, by R Mosalli K Al Faleh
2006-01-19THERAPYCurley MA, Hibberd PL, Fineman LD, et al., Effect of prone positioning on clinical outcomes in children with acute lung injury: a randomized controlled trial
JAMA 2005 Jul 13;294(2):229-37 [abstract]
Review, by M Paden
2006-01-19THERAPYKim IK, Phrampus E, Venkataraman S, et al. , Helium/oxygen-driven albuterol nebulization in the treatment of children with moderate to severe asthma exacerbations: a randomized, controlled trial.
Pediatrics 2005 Nov;116(5):1127-33 [abstract]
Review, by N Dean
2006-01-10PREDICTION TOOLConti G, Montini L, Pennisi MA, et al., A prospective, blinded evaluation of indexes proposed to predict weaning from mechanical ventilation
Intensive Care Med 2004 May;30(5):830-6 [abstract]
Review, by A Wratney
2005-12-27THERAPYSpragg RG, Lewis JF, Walmrath HD, et al., Effect of recombinant surfactant protein C-based surfactant on the acute respiratory distress syndrome
N Engl J Med 2004 351:884-892 [abstract]
Review, by F Norozian
2005-12-20THERAPYFioretto JR, De Moraes MA, Bonatto RC, et al., Acute and sustained effects of early administration of inhaled nitric oxide to children with acute respiratory distress syndrome
Pediatric Critical Care Medicine 2004 Sep;5(5):469-74 [abstract]
Review, by J Matchey
2005-12-12PREDICTION TOOLPeters MJ, Ross-Russell RI, White D , et al, Early severe neutropenia and thrombocytopenia identifies the highest risk cases of severe meningococcal disease
Pediatric Critical Care Medicine 2005 2:225-231 [abstract]
Review, by A Gourishankar
2005-12-10SYSTEMATIC REVIEWHind D, Calvert N, McWilliams R, et al., Ultrasonic locating devices for central venous cannulation: meta-analysis
Br Med J 2003 327(7411):361 [abstract]
Review, by E Harry
2005-11-25PREDICTION TOOLGomes Cordeiro AM, Fernandes JC, Troster EJ., , Possible risk factors associated with moderate or severe airway injuries in children who underwent endotracheal intubation
Crit Care Med 2004 Jul;5(4):364-8 [abstract]
Review, by A Wratney
2005-11-23THERAPYDavid M, Weiler N, Heinrichs W, et al, High-frequency oscillatory ventilation in adult acute respiratory distress syndrome
Intensive Care Med 2003 Oct;29(10):1656-65 [abstract]
Review, by J O'Rourke N Mehta
2005-11-17THERAPYWheeler DS, Jacobs BR, Kenreigh CA, et al., Theophylline versus terbutaline in treating critically ill children with status asthmaticus: A prospective, randomized, controlled trial
Pediatric Critical Care Medicine 2005 Mar;6(2):142-147 [abstract]
Review, by A Sharangpani J Natale
2005-11-17PREDICTION TOOLCarter BG, Butt W., , , A prospective study of outcome predictors after severe brain injury in children
Intensive Care Med 2005 Jun;31(6):840-845 [abstract]
Review, by L Thompson
2005-11-04THERAPYLim DS, Kulik TJ, Kim DW, Charpie JR, Crowley DC, Maher KO. Aminophylline for the prevention of apnea during prostaglandin E1 infusion
Pediatrics 2003 Jul;112(1 Pt 1):e27-9 [abstract]
Review, by P Alexander
2005-11-02PREDICTION TOOLMalerba G, Romana-Girard F, Cravoisy A, et al., Risk factors of relative adrenocortical deficiency in intensive care patients needing mechanical ventilation
Intensive Care Med 2005 31:388-392 [abstract]
Review, by AP Davis
2005-10-31THERAPYWang M, Hays T, Balasa V, et al., Low-dose tissue plasminogen activator thrombolysis in children
J Pediatr Hematol Oncol 2003 25(5):379-86 [abstract]
Review, by M Rafay
2005-10-05SYSTEMATIC REVIEWQuiroz R, Kucher N, Zou KH, et al., Clinical Validity of a Negative Computed Tomography Scan in Patients With Suspected Pulmonary Embolism: A Systematic Review
JAMA 2005 Apr 27;293(16):2012-2017 [abstract]
Review, by S Hanson
2005-09-16PREDICTION TOOLMorris MC, Wernovsky G, Nadkarni VM, , Survival outcomes after extracorporeal cardiopulmonary resuscitation instituted during active chest compressions following refractory in-hospital pediatric cardiac arrest
Pediatric Critical Care Medicine 2005 Sep;5(5):440-446 [abstract]
Review, by M Frazier A Wratney
2005-09-05DIAGNOSISMentec H, May-Michelangeli L, Rabbat A, et al., Blind and bronchoscopic sampling methods in suspected ventilator-associated pneumonia: A multicentre prospective study
Intensive Care Med 2004 30-1319-1326. [abstract]
Review, by M Weber
2005-08-24PREDICTION TOOLPizarro CF, Troster EJ, Damiani D, Carcillo JA., Absolute and relative adrenal insufficiency in children with septic shock.
Crit Care Med 2005 Apr;33(4):855-859 [abstract]
Review, by A Hsu MJ Bell
2005-07-30THERAPYWillson DF, Thomas NJ, Markovitz BP,, et al. , Effect of Exogenous Surfactant (Calfactant) in Pediatric Acute Lung Injury: A Randomized Controlled Trial
JAMA 2005 293 470-476 [abstract]
Review, by A Shieh Czaja
2005-07-11PREDICTION TOOLGraf WD, Cummings P, Quan L, Brutocao D. , Predicting outcome in pediatric submersion victims
Ann Emerg Med 1995 Sep;26(3):312-9 [abstract]
Review, by A Godshall
2005-07-05THERAPYPark M, Sangean MC, de S Volpe M, et al., Randomized, prospective trial of oxygen, continuous positive airway pressure, and bilevel positive airway pressure by face mask in acute cardiogenic pulmonary edema.
Crit Care Med 2004 Dec;32(12):2407-15 [abstract]
Review, by J Kane MD, Medical College Wisconsin, Milwaukee, WI
2005-06-18PREDICTION TOOLKurachek SC, Newth CJ, Quasney MW, et al., Extubation failure in pediatric intensive care: A multiple-center study of risk factors and outcomes
Crit Care Med 2003 Nov;31(11):2657-64 [abstract]
Review, by S Primis A Wratney
2005-05-24OUTCOMESRossi AF, Khan DM, Hannan R, et al, Goal-directed medical therapy and point-of-care testing improve outcomes after congenital heart surgery
Intensive Care Med 2005 Jan;31(1):98-104 [abstract]
Review, by M Drayer R Harrison
2005-05-19PROGNOSISHorisberger T, Fischer JE, Fanconi S. One-year survival and neurological outcome after pediatric cardiopulmonary resuscitation
Intensive Care Med 2002 28: 365-368. [abstract]
Review, by P Prodhan, N Noviski
2005-05-06THERAPYHoffman GM, Tweddell JS, Ghanayem NS, et al., Alteration of the critical arteriovenous oxygen saturation relationship by sustained afterload reduction after the Norwood procedure
J Thorac Cardiovasc Surg 2004 Mar;127(3):738-45 [abstract]
Review, by N Lin
2005-05-03HARMLandrigan CP, Rothschild JM, Cronin JW, et al., Effect of reducing interns' work hours on serious medical errors in intensive care units
N Engl J Med 2004 Oct 28;351(18):1838-48 [abstract]
Review, by L Huang J Lajoie
2005-04-28THERAPYNHLBI ARDS Clinical Trials Network, , , , Higher versus Lower Positive End-Expiratory Pressures in Patients with the Acute Respiratory Distress Syndrome
N Engl J Med 2004 351:327-336 [abstract]
Review, by M White
2005-04-13SYS-REVIEWKeenan SP, Sinuff T, Cook DJ, Hill NS. Does noninvasive positive pressure ventilation improve outcome in acute hypoxemic respiratory failure? A systematic review.
Crit Care Med 2004 Dec;32(12):2516-23 [abstract]
Review, by K Yen
2005-04-07PREDICTION TOOLClancy RR, McGaurn SA, Wernovsky G, et al., Risk of seizures in survivors of newborn heart surgery using deep hypothermic circulatory arrest
Pediatrics 2003 111(3):592-601 [abstract]
Review, by G Deshpande A Torres
2005-03-19DIAGNOSTIC TECHLevy RL, Chiavacci RM, Nicolson SC , et al. , An Evaluation of a Noninvasive Cardiac Output Measurement Using Partial Carbon Dioxide Rebreathing in Children
Anesth Analg 2004 99 1642-1647 [abstract]
Review, by M Weber
2005-03-13SYSTEMATIC REVIEWMcIntyre LA, Fergusson DA, Hebert PC, et al., Prolonged Therapeutic Hypothermia After Traumatic Brain Injury in Adults: A Systematic Review
JAMA 2003 289 2992-2999 [abstract]
Review, by N Shafi M Mariscalco
2005-03-13SYSTEMATIC REVIEWHenderson WR, Dhingra VK, Chittock DR, et al., Hypothermia in the management of traumatic brain injury. A systematic review and meta-analysis.
Br Med J 2003 Oct;29(10):1637-44 [abstract]
Review, by N Shafi M Mariscalco
2005-03-08THERAPYMeert KL, Daphtary KM, Metheny NA, , Gastric vs Small-Bowel Feeding in Critically Ill Children Receiving Mechanical Ventilation: A Randomized Controlled Trial
Chest 2004 126 872-878 [abstract]
Review, by S Rishmawi
2005-03-06PREDICTIONCharpie JR, Dekeon MK, Goldberg CS, Mosca RS, Bove EL, Kulik TJ. Serial blood lactate measurements predict early outcome after neonatal repair or palliation for complex congenital heart disease.
J Thorac Cardiovasc Surg. 2000 Jul;120(1):73-80 [abstract]
Review, by A Gazit
2005-03-03META-ANALYSISAnnane D, Bellissant E, Bollaert PE, et al., Corticosteroids for severe sepsis and septic shock: a systematic review and meta-analysis
Br Med J 2004 329(7464):480 [abstract]
Review, by M Desai
2005-03-02PREDICTION TOOLBechtel K, Stoessel K, Leventhal JM , et al., Characteristics That Distinguish Accidental From Abusive Injury in Hospitalized Young Children With Head Trauma
Pediatrics 2004 114 165-168 [abstract]
Review, by M Winkler
2005-03-01PREDICTION TOOLSrinivasan V, Spinella PC, Drott HR, et al., Association of timing, duration, and intensity of hyperglycemia with intensive care unit mortality in critically ill children.
Pediatric Critical Care Medicine 2004 Jul;5(4):329-36 [abstract]
Review, by A Bass
2005-02-28THERAPY/PREVENTIONGalban C, Montejo JC, Mesejo A, et al., An immune-enhancing enteral diet reduces mortality rate and episodes of bacteremia in septic intensive care unit patients
Crit Care Med 2000 28(3):643-8 [abstract]
Review, by R Rastmanesh
2005-02-27THERAPY/PREVENTIONTaylor RW, Zimmerman JL, Dellinger RP, et al., Low-dose inhaled nitric oxide in patients with acute lung injury: a randomized controlled trial
JAMA 2004 Apr 7;291(13):1603-9 [abstract]
Review, by R Orellana
2005-02-20PROGNOSISHamrick SE, Gremmels DB, Keet CA, et al., Neurodevelopmental outcome of infants supported with extracorporeal membrane oxygenation after cardiac surgery
Pediatrics 2003 Jun;111(6 Pt 1):e671-5 [Full-Text]
Review, by S Cooper
2005-02-14THERAPY/PREVENTIONLeon C, Ruiz-Santana S, Rello J, et al., Benefits of minocycline and rifampin-impregnated central venous catheters: A prospective, randomized, double-blind, controlled, multicenter trial
Intensive Care Med 2004 30:1891-1899 [abstract]
Review, by A Jeyapalan
2005-01-25PREDICTION TOOLFarias JA, Alía I, Retta A, et al., An evaluation of extubation failure predictors in mechanically ventilated infants and children
Intensive Care Med 2002 28:752-757 [abstract]
Review, by A Wratney DK Benjamin
2005-01-21THERAPY Meert KL, Daphtary KM, Metheny NA, , Gastric vs Small-Bowel Feeding in Critically Ill Children Receiving Mechanical Ventilation: A Randomized Controlled Trial
Chest 2004 126 872-878 [abstract]
Review, by D Hsing A Madikians
2005-01-18PROGNOSISFoland JA, Fortenberry JD, Warshaw BL, et al., Fluid overload before continuous hemofiltration and survival in critically ill children: a retrospective analysis
Crit Care Med 2004 Aug;32(8):1771-6 [abstract]
Review, by L Thompson
2005-01-13PROGNOSISPalchak MJ, Holmes JF, Vance CW, et al., Does an isolated history of loss of consciousness or amnesia predict brain injuries in children after blunt head trauma?
Pediatrics 2004 Jun;113(6):e507-13 [abstract]
Review, by K Typpo
2005-01-10THERAPYEsteban A, Frutos-Vivar F, Ferguson ND, et al., Noninvasive Positive-Pressure Ventilation for Respiratory Failure after Extubation
N Engl J Med 2004 350:2452-2460 [abstract]
Review, by T Cholis
2004-12-22THERAPY/PREVENTIONSlota M, Green M, Farley A, Janosky J, Carcillo J The role of gown and glove isolation and strict handwashing in the reduction of nosocomial infection in children with solid organ transplantation
Crit Care Med 2001 29(2):405-412 [abstract]
Review, by A Lin
2004-12-16THERAPYDahlem P, van Aalderen WMC, de Neef M, Dijkgraaf MGW, Bos AP Randomized controlled trial of aerosolized prostacyclin therapy in children with acute lung injury
Crit Care Med 2004 32:1055-1060 [abstract]
Review, by AA Arikan
2004-12-07PROGNOSISBandla HPR, Hopkins RL, Beckerman RC, Gozal D, Pulmonary Risk Factors Compromising Postoperative Recovery After Surgical Repair for Congenital Heart Disease
Chest 1999 116:740-747 [abstract]
Review, by J Geracht J Barron
2004-12-06THERAPYGupta AA, Leaker M, Andrew M, et al. , Safety and outcomes of thrombolysis with tissue plasminogen activator for treatment of intravascular thrombosis in children
J Pediatr 2001 139(5):682-8 [abstract]
Review, by J Berger
2004-11-30ECONOMIC ANALYSISAngus DC, Linde-Zwirble WT, PROWESS Investigators, , Cost-effectiveness of drotrecogin alfa (activated) in the treatment of severe sepsis
Crit Care Med 2003 Jan;31(1):1-11 [abstract]
Review, by N Mehta
2004-10-28THERAPYChastre J, Wolff M, Fagon J-Y, et al., Comparison of 8 vs 15 Days of Antibiotic Therapy for Ventilator-Associated Pneumonia in Adults: A Randomized Trial
JAMA 2003 290 2588-2598 [abstract]
Review, by J Cortes
2004-10-27THERAPYWenzel V, Krismer AC, Arntz HR, et al., A Comparison of Vasopressin and Epinephrine for Out-of-Hospital Cardiopulmonary Resuscitation
N Engl J Med 2003 350:105-113 [abstract]
Review, by K Denev
2004-10-23THERAPYThill PJ, McGuire JK, Baden HP, et al., Noninvasive positive-pressure ventilation in children with lower airway obstruction
Pediatric Critical Care Medicine 2004 Jul;5(4):337-342 [abstract]
Review, by S Rishmawi
2004-10-14THERAPYNava S, Carbone G, DiBattista N, et al., Noninvasive ventilation in cardiogenic pulmonary edema: a multicenter randomized trial
Am J Respir Crit Care Me 2003 Dec 15;168(12):1432-7 [abstract]
Review, by L Thompson
2004-09-27THERAPYKrishnan JA, Moore D, Robeson C, et al., A Prospective, Controlled Trial of a Protocol-based Strategy to Discontinue Mechanical Ventilation
Am J Respir Crit Care Me 2004 169 673-678 [abstract]
Review, by A Lee M Nilufer
2004-09-08THERAPYTrachtman H, Cnaan A, Christen E, et al., Effect of an oral Shiga toxin-binding agent on diarrhea-associated hemolytic uremic syndrome in children: a randomized controlled trial
JAMA 2003 290(10):1337-44 [abstract]
Review, by A Daneshmand R Sanders
2004-09-05QUALITY OF LIFECulbert EL, Ashburn DA, Cullen-Dean G, et al., Quality of Life of Children After Repair of Transposition of the Great Arteries
Circulation 2003 108 857-862 [abstract]
Review, by D Stockwell J Natale
2004-09-02THERAPYWarren BL, Eid A, Singer P, et al., High-Dose Antithrombin III in Severe Sepsis: A Randomized Controlled Trial
JAMA 2001 286:1869-1878 [abstract]
Review, by K Hebbar T Petrillo
2004-08-26THERAPYSoroksky A, Stav D, Shpirer I, , A Pilot Prospective, Randomized, Placebo-Controlled Trial of Bilevel Positive Airway Pressure in Acute Asthmatic Attack
Chest 2003 123 1018-1025 [abstract]
Review, by K Lewis
2004-08-25PREDICTION TOOLDurward A, Mayer A, Skellett S, et al., Hypoalbuminaemia in critically ill children: incidence, prognosis, and influence on the anion gap
Arch Dis Child 2003 May;88(5):419-22 [abstract]
Review, by R Lambert
2004-08-24PREDICTION TOOLCastellanos-Ortega I, Delgado-Rodriguez M, Llorca J, et al., A new prognostic scoring system for meningococcal septic shock in children. Comparison with three other scoring systems.
Intensive Care Med 2002 28: 341-351 [abstract]
Review, by A Vohra
2004-08-15THERAPYSAFE Study Investigators, , , , A comparison of albumin and saline for fluid resuscitation in the Intensive Care Unit
N Engl J Med 2004 350:2247-2256 [abstract]
Review, by S van Schaik
2004-08-11THERAPYCooper DJ, Myles PS, McDermott FT, et al. Prehospital hypertonic saline resuscitation of patients with hypotension and severe traumatic brain injury: a randomized controlled trial
JAMA 2004 Mar 17;291(11):1350-7 [abstract]
Review, by G Mander
2004-08-06PROGNOSISBanwell BL, Mildner RJ, Hassall AC, et al., Muscle weakness in critically ill children
Neurology 2003 Dec 23;61(12):1779-82 [abstract]
Review, by J Alten M Mariscalco
2004-08-02PREDICTION TOOLDe Bast Y, De Backer D, Moraine JJ, et al., The cuff leak test to predict failure of tracheal extubation for laryngeal edema
Intensive Care Med 2002 28: 1267-1272 [abstract]
Review, by A Wratney DK Benjamin Jr
2004-07-16THERAPYPerondi MBM, Reis AG, Paiva EF, Nadkarni VM, Berg RA A Comparison of High-Dose and Standard-Dose Epinephrine in Children with Cardiac Arrest
N Engl J Med 2004 350:1722-1730 [abstract]
Review, by M Sharma
2004-07-06DIAGNOSISBarret JP, Ramzy PI, Wolf SE, Herndon DN, Sensitivity and Specificity of Bronchoalveolar Lavage and Protected Bronchial Brush in the Diagnosis of Pneumonia in Pediatric Burn Patients
Arch Surg 1999 134:1243-1247 [abstract]
Review, by A Vohra
2004-06-19PROGNOSISGoh AYT,, Abdel-Latif MEA, Lum LCS, Abu-Bakar MN, Outcome of children with different accessibility to tertiary pediatric intensive care in a developing country - a prospective cohort study
Intensive Care Med 2003 29: 97-102 [abstract]
Review, by J Cortes
2004-06-04THERAPYWainwright C, Altamarino L, Medico-Cirujano , et al., A Multicenter, Randomized, Double-Blind, Controlled Trial of Nebulized Epinephrine in Infants with Acute Bronchiolitis.
N Engl J Med 2003 349:27-35 [abstract]
Review, by P Prodhan N Noviski
2004-06-01PREDICTION TOOLBernal W, Donaldson N, Wyncoll D, Wendon J, Blood lactate as an early predictor of outcome in paracetamol-induced acute liver failure: a cohort study
Lancet 2002 Feb 16;359(9306):558-63 [abstract]
Review, by P Prodhan N Noviski
2004-05-21THERAPYThe Hypothermia After Cardiac Arrest Study Group. Mild Therapeutic Hypothermia to Improve the Neurologic Outcome After Cardiac Arrest
N Engl J Med 2002 346:549-56 [abstract]
Review, by S Cooper
2004-04-29PREDICTION TOOLBrown KL, Ridout DA, Goldman AP, et al., Risk factors for long intensive care unit stay after cardiopulmonary bypass in children
Crit Care Med 2003 31(1):28-33 [abstract]
Review, by A Torres
2004-04-29PREDICTION TOOLHatherill M, Waggie Z, Purves L, et al, Mortality and the nature of metabolic acidosis in children with shock
Intensive Care Med 2003 Feb;29(2):286-91 [abstract]
Review, by R Lambert A Zaritsky
2004-03-30ECONOMIC ANALYSISManns BJ, Lee H, Doig CJ, et al., An economic evaluation of activated protein C treatment for severe sepsis
N Engl J Med 2002 347:993-1000 [abstract]
Review, by A Arikan
2004-03-19PREDICTION TOOLPerez A, Minces PG, Schnitzler EJ, et al., Jugular venous oxygen saturation or arteriovenous difference of lactate content and outcome in children with severe traumatic brain injury
Pediatric Critical Care Medicine 2003 Jan;4(1):33-8 [abstract]
Review, by J Alten M Mariscalco
2004-03-05THERAPYRichard C, Warszawski J, Angurl N, et al., Early Use of the Pulmonary Artery Catheter and Outcomes in Patients With Shock and Acute Respiratory Distress Syndrome: A Randomized Controlled Trial
JAMA 2003 290 2713-2720 [abstract]
Review, by S. Thammasitboon S. Cortes
2004-02-14THERAPYFerrer M, Esquinas A, Leon M, Gonzalez G, Alarcon A, Torres A. Noninvasive ventilation in severe hypoxemic respiratory failure: a randomized clinical trial
Am J Respir Crit Care Med. 2003 Dec 15;168(12):1438-44 [abstract]
Review, by H Sahhar
2004-02-04PROGNOSISJacobe SJ, Hassan A, Veys P, Mok Q, Outcome of children requiring admission to an intensive care unit after bone marrow transplantation.
Crit Care Med 2003 31(5):1299-305 [abstract]
Review, by E Harry
2004-02-02OUTCOMESHan YY, Carcillo JA, Dragotta MA, et al., Early Reversal of Pediatric-Neonatal Septic Shock by Community Physicians Is Associated With Improved Outcome
Pediatrics 2003 112 793-799 [abstract]
Review, by N Faqih
2004-02-02THERAPY/PREVENTIONSmulders K, van der Hoeven H, Weers-Pothoff I, Vandenbroucke-Grauls C, A Randomized Clinical Trial of Intermittent Subglottic Secretion Drainage in Patients Receiving Mechanical Ventilation
Chest 2002 121: 858-862 [abstract]
Review, by M Sehgal
2004-01-06PREDICTION TOOLFinney SJ, Zekveld C, Elia A, Evans TW, Glucose control and mortality in critically ill patients
JAMA 2003 290(15):2041-7 [abstract]
Review, by A Chavez
2003-12-31THERAPYPettignano R, Fortenberry JD, Heard ML, et al., Primary use of the venovenous approach for extracorporeal membrane oxygenation in pediatric acute respiratory failure
Pediatric Critical Care Medicine 2003 4(3):291-8 [abstract]
Review, by M Sharma
2003-12-27PREDICTION TOOLRossi AF, Seiden HS, Gross RP, Griepp RB, Oxygen transport in critically ill infants after congenital heart operations
Ann Thorac Surg 1999 67(3):739-44 [abstract] [Full-Text]
Review, by A Shahin
2003-12-15THERAPYJacobs S, Price Evans DA, Tariq M, et al., Fluconazole improves survival in septic shock: A randomized double-blind prospective study
Crit Care Med 2003 Jul;31(7):1938-46 [abstract]
Review, by P Meaney
2003-12-15THERAPYDiCarlo JV, Alexander SR, Agarwal R, Schiffman JD, Continuous veno-venous hemofiltration may improve survival from acute respiratory distress syndrome after bone marrow transplantation or chemotherapy
J Pediatr Hematol Oncol 2003 Oct;25(10):801-5 [abstract]
Review, by E Cullen
2003-12-04DIAGNOSISSirvent JM, Vidaur L, Gonzalez S, et al., Microscopic examination of intracellular organisms in protected bronchoalveolar mini-lavage fluid for the diagnosis of ventilator-associated pneumonia
Chest 2003 123(2):518-23 [abstract]
Review, by C Kennedy
2003-11-24THERAPYPatel H, Platt RW, Pekeles GS, Ducharme FM, A randomized, controlled trial of the effectiveness of nebulized therapy with epinephrine compared with albuterol and saline in infants hospitalized for acute viral bronchiolitis
J Pediatr 2002 141(6):818-24 [abstract]
Review, by R Lambert R Sanders
2003-11-14DIAGNOSISMarik PE, Zaloga GP, , , Adrenal insufficiency during septic shock
Crit Care Med 2003 31(1):141-5 [abstract]
Review, by P Prabhakaran
2003-11-04THERAPYFerrer M, Esquinas A, Arancibia F, et al., Non-invasive ventilation during persistent weaning failure. A randomized controlled trial
Am J Respir Crit Care Me 2003 168(1):70-6 [abstract]
Review, by L Smith
2003-10-13SYSTEMATIC REVIEWHeyland DK, Novak F, Drover JW , et al., Should Immunonutrition Become Routine in Critically Ill Patients? A Systematic Review of the Evidence
JAMA 2001 286:944-953 [abstract]
Review, by N Mehta
2003-10-06PROGNOSISDe Jonghe B, Sharshar T, Lefaucheur JP, et al., Paresis acquired in the intensive care unit: a prospective multicenter study
JAMA 2002 288(22):2859-67 [abstract]
Review, by J Alten
2003-09-26THERAPYMoller JC, Schaible T, Roll C, et al., Treatment with bovine surfactant in severe acute respiratory distress syndrome in children: a randomized multicenter study
Intensive Care Med 2003 29(3):437-46 [abstract]
Review, by N Mehta
2003-09-24SYSTEMATIC REVIEWSokol J, Jacobs SE, Bohn D, , Inhaled nitric oxide for acute hypoxemic respiratory failure in children and adults
Cochrane Review 2002 Issue 4 2002. Oxford: Update Software [abstract]
Review, by S Thammasitboon S Thammasitboon
2003-09-15PREDICTION TOOLRobertson CMT, Joffe AR, Moore AJ, Watt JM, Neurodevelopmental outcome of young pediatric intensive care survivors of serious brain injury
Pediatric Critical Care Medicine 2002 3(4):345-350 [abstract]
Review, by R Graham
2003-08-29THERAPYHoffman TM, Wernovsky G, Atz AM, et al., Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease
Circulation 2003 Feb 25;107(7):996-1002 [abstract]
Review, by A Torres
2003-07-25SYSTEMATIC REVIEWHo AMH, Lee A, Karmakar MK , et al., Heliox vs Air-Oxygen Mixtures for the Treatment of Patients With Acute Asthma: A Systematic Overview
Chest 2003 123 882-890 [abstract]
Review, by G Wolf
2003-07-07PROGNOSISMarcin JP, Glaser N, Barnett P, et al., Factors associated with adverse outcomes in children with diabetic ketoacidosis-related cerebral edema
J Pediatr 2002 141(6):793-7 [abstract]
Review, by C Kennedy
2003-07-06PROGNOSISLamas A, Otheo E, Ros P, et al., Prognosis of child recipients of hematopoietic stem cell transplantation requiring intensive care
Intensive Care Med 2003 29: 91-96 [abstract]
Review, by L Hite
2003-06-24THERAPYMartin GS, Mangialardi RJ, Wheeler AP, et al, Albumin and furosemide therapy in hypoproteinemic patients with acute lung injury
Crit Care Med 2002 30(10):2175-82 [abstract]
Review, by D Godorov
2003-06-21THERAPYWeaver LK, Hopkins RO, Chan KJ , et al., Hyperbaric oxygen for acute carbon monoxide poisoning
N Engl J Med 2002 347:1057-67 [abstract]
Review, by M Fiore
2003-06-16THERAPYOlschewski H, Simmoneau G, Galie N, et al., Inhaled Iloprost for Severe Pulmonary Hypertension
N Engl J Med 2002 347(5):322-9 [abstract]
Review, by A Arikan
2003-06-12THERAPY Inhaled Nitric Oxide and Hypoxic Respiratory Failure in Infants With Congenital Diaphragmatic Hernia
Pediatrics 1997 99: 838-845 [abstract]
Review, by The Neonatal Inhaled Nitric Oxide Study Group (NINOS)
2003-05-22PREDICTION TOOLBersten AD, Hunt T, Nicholas TE, et al., Elevated Plasma Surfactant Protein-B Predicts Development of Acute Respiratory Distress Syndrome in Patients with Acute Respiratory Failure
Am J Respir Crit Care Me 2001 164 648-652 [abstract]
Review, by S Huntoon Vitali
2003-05-17ICU OUTCOMESBulger EM, Nathens AB, Rivara FP, et al., Management of severe head injury: institutional variations in care and effect on outcome
Crit Care Med 2002 30(8):1870-6 [abstract]
Review, by J Adler
2003-05-07THERAPYArons MM, Wheller AP, Bernard GR, et al., Effects of ibuprofen on the physiology and survival of hypothermic sepsis
Crit Care Med 1999 27:699-707 [abstract]
Review, by W Arias
2003-05-04SYSTEMATIC REVIEWKern JW, Shoemaker WC, , , Meta-analysis of hemodynamic optimization in high-risk patients
Crit Care Med 2002 30(8):1686-92 [abstract]
Review, by S Thammasitboon S Thammasitboon
2003-04-25THERAPYRandolph AG, Wypij D, Venkataraman ST, et al., for PALISI network Effect of Mechanical Ventilator Weaning Protocols on Respiratory Outcomes in Infants and Children: A Randomized Controlled Trial
JAMA 2002 288:2561-2568 [abstract]
Review, by M Twite
2003-04-21THERAPYHerndon DN, Hart DW, Wolf SE, et al., Reversal of catabolism by beta-blockade after severe burns
N Engl J Med 2001 345: 1223-1229 [abstract]
Review, by M Sharma K Meert
2003-04-14THERAPYMiura E, Procianoy RS, Bittar C , et al., A Randomized, Double-Masked, Placebo-Controlled Trial of Recombinant Granulocyte Colony-Stimulating Factor Administration to Preterm Infants With the Clinical Diagnosis of Early-Onset Sepsis
Pediatrics 2001 107:30-35 [abstract]
Review, by W Arias
2003-04-04PREDICTION TOOLLimperopoulos C, Majnemer A, Shevell MI, et al., Predictors of developmental disabilities after open heart surgery in young children with congenital heart defects
J Pediatr 2002 141(1):51-8 [abstract]
Review, by L Elbahlawan
2003-04-02HARMSchmugge M, Risch L, Huber A, Fischer JE, Heparin-Induced Thrombocytopenia-Associated Thrombosis in Pediatric Intensive Care Patients
Pediatrics 2002 109:e10 [abstract]
Review, by K Mistry
2003-03-24THERAPYLopriore , Markhorst D, Gemke RJBJ, , Ventilator-associated pneumonia and upper airway colonisation with Gram negative bacilli: the role of stress ulcer prophylaxis in children
Intensive Care Med 2002 28: 763-767 [abstract]
Review, by D Godorov
2003-03-14SYSTEMATIC REVIEWMarkovitz BP, Randolph AG, , , Corticosteroids for the Prevention of Reintubation and Postextubation Stridor in Pediatric Patients: A Meta-Analysis
Pediatric Critical Care Medicine 2002 3:223-226 [abstract] [Full-Text]
Review, by K Brinkman
2003-03-10THERAPY/PREVENTIONCorwin HL, Gettinger A, Pearl RG, et al. , Efficacy of recombinant human erythropoietin in critically ill patients: a randomized controlled trial
JAMA 2002 288(22):2827-35 [abstract]
Review, by M Cooper
2003-03-10THERAPYPolderman KH, Joe RTT, Peerdeman SM , et al., Effects of therapeutic hypothermia on intracranial pressure and outcome in patients with severe head injury
Intensive Care Med 2002 28: 1563-1573 [abstract]
Review, by S Thammasitboon S Thammasitboon
2003-03-09THERAPY/PREVENTIONQureshi F, Zaritsky A, Poirier MP, , Comparative efficacy of oral dexamethasone versus oral prednisone in acute pediatric asthma
J Pediatr 2001 139(1):20-6 [abstract]
Review, by A Torres
2003-03-02THERAPYBettendorf M, Schmidt KG, Grulich-Henn J, et al., Tri-iodothyronine treatment in children after cardiac surgery: a double-blind, randomised, placebo-controlled study
Lancet 2000 356(9229):529-34 [abstract]
Review, by L Rajagopalan
2003-02-08HARMTaylor RW, Manganaro L, O'Brien J, Trottier SJ, Parkar N, Veremakis C. Impact of allogenic packed red blood cell transfusion on nosocomial infection rates in the critically ill patient
Crit Care Med 2002 30(10):2249-54 [abstract]
Review, by R Orellana
2003-01-20THERAPYEsteban A, Alia I, Gordo F, et al. , Prospective Randomized Trial Comparing Pressure-Controlled Ventilation and Volume-Controlled Ventilation in ARDS
Chest 2000 117(6):1690-1696 [abstract] [Full-Text]
Review, by A Pelaez
2003-01-17THERAPY/PREVENTIONNtoumenopoulos G, Presneill JJ, McElholum M, Cade JF, Chest physiotherapy for the prevention of ventilator-associated pneumonia
Intensive Care Med 2002 28: 850-856 [abstract]
Review, by N Hoover J Stockwell
2003-01-07THERAPYDerdak S, Mehta S, Stewart TE, et al., High-Frequency Oscillatory Ventilation for Acute Respiratory Distress Syndrome in Adults
Am J Respir Crit Care Me 2002 166:801-808 [abstract]
Review, by K Ventre
2002-12-26THERAPYBusund R, Koukline V, Utrobin U, et al., Plasmapheresis in severe sepsis and septic shock: a prospective, randomised, controlled trial
Intensive Care Med 2002 28: 1434-1439 [abstract]
Review, by J Krishnan V Vaiyda
2002-12-04SYSTEMATIC REVIEWMarin MG, Lee JC, Skurnick JH, , Prevention of nosocomial bloodstream infections: effectiveness of antimicrobial-impregnated and heparin-bonded central venous catheters
Crit Care Med 2000 Sep;28(9):3332-8 [abstract]
Review, by K Mistry
2002-11-24PREDICTIONHackbarth RM, Rzeszutko KM, Sturm G, et al. Survival and functional outcome in pediatric traumatic brain injury: a retrospective review and analysis of predictive factors
Crit Care Med 2002 30(7):1630-5 [abstract]
Review, by J Krishnan, W Morrison
2002-11-06THERAPY/PREVENTIONAnnane D, Sebille V, Charpentier C, et al., Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock
JAMA 2002 288(7):862-71 [abstract] [Full-Text]
Review, by P Kamat J Fortenberry
2002-11-03PREDICTION TOOLNuckton TJ, Alonso JA, Kallet RH, et a;/, Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome
N Engl J Med 2002 346(17):1281-6 [abstract]
Review, by S Kannan K Meert
2002-11-01ECONOMIC ANALYSISRainer TH, Jacobs P, Ng YC , et al, Cost effectiveness analysis of intravenous ketorolac and morphine for treating pain after limb injury: double blind randomised controlled trial
Br Med J 2000 321:1247-1252 [abstract] [Full-Text]
Review, by A Torres
2002-10-20PREDICTIONKhamiees M, Raju P, DeGirolamo A, Amoateng-Adjepong Y, Manthous CA. Predictors of Extubation Outcome in Patients Who Have Successfully Completed a Spontaneous Breathing Trial
Chest 2001 120 1262-1270 [abstract]
Review, by J Barron
2002-10-01THERAPYLuchetti M, Ferrero F, Gallini C, et al., Multicenter randomized, controlled study of porcine surfactant in severe respiratory syncytial virus-induced respiratory failure
Pediatric Critical Care Medicine 2002 3:261-268 [abstract] [Full-Text]
Review, by M Wilhelm
2002-09-24THERAPYMartinon-Torres F, Rodriguez-Nunez A, Martinon-Sanchez JM, , Heliox Therapy in Infants With Acute Bronchiolitis
Pediatrics 2002 109:68-73 [abstract] [Full-Text]
Review, by H Trivedi K Biagas
2002-09-20PREDICTION TOOLUusaro A, Chittock DR, Russell JA, , Stress test and gastric-arterial PCO2 measurement improve prediction of successful extubation
Crit Care Med 2000 28(7):2313-9 [abstract]
Review, by N Hoover A Vats
2002-09-06THERAPYSmyrnios NA, Connolly A, Wilson MM, , Effects of a multifaceted, multidisciplinary, hospital-wide quality improvement program on weaning from mechanical ventilation
Crit Care Med 2002 30(6):1224-30 [abstract]
Review, by S Thammasitboon S Thammasitboon
2002-09-05PROGNOSISMangialardi RJ, Martin GS, Bernard GR, et al., Hypoproteinemia predicts acute respiratory distress syndrome development, weight gain, and death in patients with sepsis
Crit Care Med 2000 28(9):3137-45 [abstract]
Review, by N Faqih
2002-08-26PREDICTION TOOLWells RG, Vetter C, Laud P, , Intracranial hemorrhage in children younger than 3 years: prediction of intent
Arch Pediatr Adolesc Med 2002 156(3):252-7 [abstract]
Review, by G Capraro S Bateman
2002-08-21SYSTEMATIC REVIEWWilkes MM, Navick RJ, , , Patient Survival after Human Albumin Administration A Meta-Analysis of Randomized, Controlled Trials
Ann Intern Med 2001 135:149-164 [abstract]
Review, by A Torres
2002-08-19PREDICTIONViccellio P, Simon H, Pressman BD, et al. A Prospective Multicenter Study of Cervical Spine Injury in Children
Pediatrics 2001 2001;108 e20 [abstract] [Full-Text]
Review, by K Moynihan Hardart
2002-08-13HARMVan Houten MA, Uiterwaal CS, Heesen GJ, et al., Does the empiric use of vancomycin in pediatrics increase the risk for Gram-negative bacteremia?
Pediatr Infect Dis J 2001 20(2):171-7 [abstract]
Review, by C Kennedy
2002-07-26ICU OUTCOMESNathens AB, Jurkovich GJ, Maier RV , et al., Relationship between trauma center volume and outcomes
JAMA 2001 285(9):1164-71 [abstract] [Full-Text]
Review, by K Hardart
2002-07-22THERAPYFarias JA, Retta A, et al., , A comparison of two methods to perform a breathing trial before extubation in pediatric intensive care patients
Intensive Care Med 2001 27:1649-1654 [abstract]
Review, by A Arikan M McPherson
2002-07-15THERAPY/PREVENTIONBergmans DCJJ, Bonten MJM, Gaillard CA, et al., Prevention of Ventilator-associated Pneumonia by Oral Decontamination A Prospective, Randomized, Double-blind, Placebo-controlled Study
Am J Respir Crit Care Me 2001 164:382-388 [abstract]
Review, by P Kamat J Stockwell
2002-07-13THERAPY/PREVENTIONClancy RR, MCGaurn SA, Goin JE, et al., Allopurinol Neurocardiac Protection Trial in Infants Undergoing Heart Surgery Using Deep Hypothermic Circulatory Arrest
Pediatrics 2001 108 61-70 [abstract] [Full-Text]
Review, by A Shahin
2002-06-06THERAPYSchiffl H, Lang SM, Fischer R, , Daily hemodialysis and the outcome of acute renal failure
N Engl J Med 2002 346:305-10 [abstract]
Review, by X Garcia
2002-05-15THERAPYBernard SA, Gray TW, Buist MD, , Treatment of Comatose Survivors of Out-of-Hospital Cardiac Arrest with Induced Hypothermia
N Engl J Med 2002 346:557-63 [abstract]
Review, by M Sehgal
2002-05-05THERAPYGattinoni L, Tognoni G, Pesenti A, et al., Effect of Prone Positioning on the Survival of Patients with Acute Respiratory Failure
N Engl J Med 2001 345:568-573 [abstract]
Review, by P Kamat
2002-05-05THERAPYDorian P, Cass D, Schwartz B, et al., Amiodarone as compared with lidocaine for shock-resistant ventricular fibrillation
N Engl J Med 2002 346(12):884-90 [abstract]
Review, by J Keates Baleeiro K Meert
2002-04-27DIAGNOSISWells PS, Anderson DR, Rodger M, , Excluding Pulmonary Embolism at the Bedside without Diagnostic Imaging: Management of Patients with Suspected Pulmonary Embolism Presenting to the Emergency Department by Using a Simple Clinical Model and D-dimer
Ann Intern Med 2001 135:98-107 [abstract] [Full-Text]
Review, by D Mackey
2002-04-12ICU OUTCOMESMorrison AL, Gillis J, O'Connell AJ, , Quality of life of survivors of pediatric intensive care
Pediatric Critical Care Medicine 2002 3:1-5 [abstract]
Review, by K Ventre
2002-04-01THERAPY Rivers E, Nguyen B, Havstad S, et al. , Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock
N Engl J Med 2001 345:1368-77 [abstract]
Review, by S Thammasitboon M Mcpherson
2002-03-26HARMMerrer J, De Jonghe B, Golliot F, , Complications of Femoral and Subclavian Venous Catheterization in Critically Ill Patients: A Randomized Controlled Trial
JAMA 2001 286:700-707 [abstract]
Review, by J Foland T Petrillo
2002-03-23PROGNOSISParra DA, Totapally BR, Zahn E, , Outcome of cardiopulmonary resuscitation in a pediatric cardiac intensive care unit
Crit Care Med 2000 28(9):296-300 [abstract]
Review, by KP Mistry
2002-03-22THERAPYHilbert G, Gruson D, Vargas F , , Noninvasive ventilation in immunosuppressed patients with pulmonary infiltrates, fever, and acute respiratory failure
N Engl J Med 2001 344(7):481-7 [abstract]
Review, by J Barron
2002-03-14PREDICTION TOOLTilford JM, Simpson PM, Yeh TS, , Variation in therapy and outcome for pediatric head trauma patients
Crit Care Med 2001 29:1056-1061 [abstract]
Review, by L Faberowski
2002-03-08PREDICTION TOOLHaydel MJ, Preston CA, Mills TJ, , Indications for computed tomography in patients with minor head injury
N Engl J Med 2000 343:100-5 [abstract]
Review, by M Sehgal MM Mariscalco
2002-03-02THERAPYVan den Berghe G, Wouter P, Weeker F, , Intensive Insulin Therapy in Critically Ill Patients
N Engl J Med 2001 345:1359-67 [abstract]
Review, by N Hoover A Vats
2002-02-22PREDICTION TOOLCantais E, Paut O, Giorgi R , , Evaluating the prognosis of multiple, severely traumatized children in the intensive care unit
Intensive Care Med 2001 27: 1511-1517; DOI 10.1007/s001340101039 [abstract]
Review, by A Torres
2002-02-13THERAPYPutensen C, Zech S, Wrigge H , , Long-Term Effects of Spontaneous Breathing During Ventilatory Support in Patients with Acute Lung Injury
Am J Respir Crit Care Me 2001 27: 1511-1517; DOI 10.1007/s001340101039 [abstract]
Review, by S Kache V Kesavulu
2001-12-20THERAPYBernard GR, Vincent JL, Laterre PF, , Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis
N Engl J Med 2001 344:699-709 [abstract] [Full-Text]
Review, by D Vaughn
2001-12-17SYSTEMATIC REVIEWKellum JA, M Decker J, , , Use of dopamine in acute renal failure: a meta-analysis
Crit Care Med 2001 1526-31 [abstract]
Review, by C Davison
2001-12-13SURROGATE/THERAPYReam RS, Loftis LL, Albers GM, , Efficacy of IV Theophylline in Children With Severe Status Asthmaticus
Chest 2001 119:1480-1488 [abstract] [Full-Text]
Review, by M Chavolla
2001-11-22DIAGNOSISHoffman JR, Mower WR, Wolfson AB, Todd KH, Zucker MI Validity of a Set of Clinical Criteria to Rule Out Injury to the Cervical Spine in Patients with Blunt Trauma
N Engl J Med 2000 ul 13;343(2):94-99 [abstract]
Review, by A Torres
2001-11-13SURROGATE/THERAPYWeber JE, Chudnofsky CR, Younger JG, et al., A randomized comparison of helium-oxygen mixture (heliox) and racemic epinephrine for the treatment of moderate to severe croup
Pediatrics 2001 Jun;107(6):E96 [abstract] [Full-Text]
Review, by M Cooper
2001-11-11SURROGATE/THERAPYMorris K, Beghetti M, Petros A, Adatia I, Bohn D Comparison of hyperventilation and inhaled nitric oxide for pulmonary hypertension after repair of congenital heart disease
Crit Care Med 2000 28(8):2974-8 [abstract]
Review, by R Rao
2001-10-31SURROGATERanieri VM, Suter PM, Tortorella C, et al. Effect of Mechanical Ventilation on Inflammatory Mediators in Patients with Acute Respiratory Distress Syndrome: A Randomized Controlled Trial
JAMA 1999 282:54-61 [abstract] [Full-Text]
Review, by S Kache, R Harrison
2001-09-21SYSTEMATIC REVIEWOstermann ME, Keenan SP, Seiferling RA, Sibbald WJ Sedation in the Intensive Care Unit. A Systematic Review
JAMA 2000 283:1451-1459 [abstract] [Full-Text]
Review, by P Jines
2001-09-08THERAPYClifton GL, Miller ER, Choi SC, , Lack of Effect of Induction of Hypothermia after Acute Brain Injury
N Engl J Med 2001 344:556-63 [abstract]
Review, by P Prabhakaran
2001-08-25PREDICTION TOOLGreenes DS, Schutzman SA., , , Clinical Indicators of Intracranial Injury in Head-injured Infants
Pediatrics 1999 104: 861-867 [abstract] [Full-Text]
Review, by P Tandon S Bateman
2001-08-18DIAGNOSTIC TECHTibby SM, Hatherill M, Durward A, Murdoch IA, Are transoesophageal Doppler parameters a reliable guide to paediatric haemodynamic status and fluid management?
Intensive Care Med 2001 27:201-205 [abstract]
Review, by M Duthie O Bagshaw
2001-08-09PREDICTION TOOLHatherill M, McIntyre AG, Wattie M, Murdoch IA, Early hyperlactataemia in critically ill children
Intensive Care Med 2000 26:314-318 [abstract]
Review, by R Graham
2001-08-03THERAPYTibby SM, Hatherill M, Wright SM, , Exogenous Surfactant Supplementation in Infants with Respiratory Syncytial Virus Bronchiolitis
Am J Respir Crit Care Me 2000 162: 1251-1256 [abstract] [Full-Text]
Review, by S Kache
2001-07-26DIAGNOSTIC TECHCoule LW, Truemper EJ, Steinhart CM, Lutin WA, Accuracy and utility of a continuous intra-arterial blood gas monitoring system in pediatric patients
Crit Care Med 2001 29(2):420-6 [abstract]
Review, by J Tuladhar
2001-07-23THERAPYCiarallo L, Brousseau D, Reinert S, , Higher-Dose Intravenous Magnesium Therapy for Children With Moderate to Severe Acute Asthma
Arch Pediatr Adolesc Med 2000 154:979-983 [abstract] [Full-Text]
Review, by M Chavolla
2001-07-20DIAGNOSTIC TESTLabenne M, Poyart C, Rambaud C, , Blind protected specimen brush and bronchoalveolar lavage in ventilated children
Crit Care Med 1999 1999 ;27:2537-43 [abstract]
Review, by R Sanders AL Graciano
2001-07-19PREDICTION TOOLMartin C, Viviand X, Leone M, Thirion X, Effect of norepinephrine on the outcome of septic shock
Crit Care Med 2000 28(8):2758-65 [abstract]
Review, by P. Prabhakaran
2001-07-13THERAPYBellomo R, Chapman M, Finfer S, Australian and New Zealand Intensive Care Society (ANZICS) Clinical Trials Group, Low-dose dopamine in patients with early renal dysfunction: a placebo-controlled randomised trial
Lancet 2000 356(9248):2139-43 [abstract]
Review, by J Barron A Madikians
2001-07-05THERAPYArnold JH, Hanson JH, Toro-Figuero LO, , Prospective, randomized comparison of high-frequency oscillatory ventilation and conventional mechanical ventilation in pediatric respiratory failure
Crit Care Med 1994 22(10):1530-9 [abstract]
Review, by X Garcia
2001-07-03DIAGNOSTIC TESTKress JP, O'Connor MF, Schmidt GA, , Clinical Examination Reliably Detects Intrinsic Positive End-Expiratory Pressure in Critically Ill, Mechanically Ventilated Patients
Am J Respir Crit Care Me 1999 159: 290-294 [abstract]
Review, by R. Orellana M. McPherson
2001-06-23THERAPYBrent J, McMartin K, Phillips S, Aaron C, Kulig K Fomepizole for the Treatment of Methanol Poisoning
N Engl J Med 2001 344:424-9 [abstract]
Review, by D. Mackey
2001-06-07SURROGATE/THERAPYKornecki A, Frndova H, , Coates AL, Shemie SD A Randomized Trial of Prolonged Prone Positioning in Children With Acute Respiratory Failure.
Chest 2001 119: 211-218 [abstract] [Full-Text]
Review, by L. Wise-Faberowski
2001-05-30SURROGATELópez-Herce J, de Lucas N, Carrillo A, Bustinza A, Moral R. Surfactant treatment for acute respiratory distress syndrome
Arch Dis Child 1999 80:248-252 [abstract]
Review, by J. Barron, A. Madikians
2001-05-30SYSTEMATIC REVIEWMessori A, Trippoli S, Vaiani M, Gorini M, Corrado A. Bleeding and pneumonia in intensive care patients given ranitidine and sucralfate for prevention of stress ulcer: meta-analysis of randomised controlled trials
Br Med J 1999 321:1103-1106 [abstract] [Full-Text]
Review, by S Cray
2001-05-23THERAPYLahat E, Goldman M, Barr J, et al., Comparison of intranasal midazolam with intravenous diazepam for treating febrile seizures in children: prospective randomised study
Br Med J 2000 321:83-86 [Full-Text]
Review, by A Torres
2001-05-22THERAPY/PREVENTIONWathen JE, Roback MG, Mackenzie T, Bothner JP, Does midazolam alter the clinical effects of intravenous ketamine sedation in children? A double-blind, randomized, controlled, emergency department trial
Ann Emerg Med 2000 36(6):579-588 [abstract]
Review, by J Haizlip
2001-05-04HARMGlaser N, Barnett P, McCaslin I, et al., Risk Factors for Cerebral Edema in Children with Diabetic Ketoacidosis
N Engl J Med 2001 344:264-9 [abstract]
Review, by R Rao M Scanlon
2001-04-18ICU OUTCOMESTilford JM, Simpson PM, Green JW, Lensing S, Fiser DH Volume-Outcome Relationships in Pediatric Intensive Care Units
Pediatrics 2000 106(2):289-294 [abstract]
Review, by J White
2001-04-12PREDICTION TOOLManczur TI, Greenough A, Pryor D, Rafferty GF, Comparison of predictors of extubation from mechanical ventilation in children.
Pediatric Critical Care Medicine 2000 1:28-32
Review, by S Venkataraman
2001-03-04SURROGATE/THERAPYRobertson CS, Valadka AB, Hannay HJ, , Prevention of secondary ischemic insults after severe head injury
Crit Care Med 1999 27:2086-95 [abstract]
Review, by JRM White
2001-02-23HARMWong CS, Jelacic S, Habeeb RL, Watkins SL, Tarr PI The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 infections
N Engl J Med 2000 342(26):1930-6 [abstract]
Review, by M. Cooper
2001-02-16THERAPYSchuh S, Reisman J, Alshehri M, Annie Dupuis, Mary Corey A comparison of inhaled fluticasone and oral prednisone for children with severe acute asthma.
N Engl J Med 2000 343(10):689-94 [abstract]
Review, by A. Torres
2001-02-06QUALITYSheridan RL, Hinson MI, Liang MH, , Long-term Outcome of Children Surviving Massive Burns
JAMA 2000 283:69-73 [abstract] [Full-Text]
Review, by R Graham
2001-01-15THERAPYMiller OI, Tang SF, Keech A, , Inhaled nitric oxide and prevention of pulmonary hypertension after congenital heart surgery: a randomised double-blind study
Lancet 2000 356:1464-1469 [abstract]
Review, by K Daphtary K Meert
2001-01-05SURROGATE END POINTCorwin HL, Gettinger A, Rodriguez RM, , Efficacy of recombinant human erythropoietin in the critically ill patient: a randomized, double-blind, placebo-controlled trial.
Crit Care Med 1999 27:2346-50 [abstract]
Review, by Prasad
2001-01-02THERAPYRoosevelt G, Sheehan K, Grupp-Phelan J, , Dexamethasone in bronchiolitis: a randomised controlled trial.
Lancet 1996 348:292-5 [abstract]
Review, by E. Stiles
2000-12-24THERAPYB?low SM, Nir M, Levin E, , Prednisolone Treatment of Respiratory Syncytial Virus Infection: A Randomized Controlled Trial of 147 Infants.
Pediatrics 1999 104: e77 [abstract] [Full-Text]
Review, by J. Hageman B. Markovitz
2000-12-21PREDICTION TOOLVenkataraman ST, Khan N, Brown A, , Validation of predictors of extubation success and failure in mechanically ventilated infants and children.
Crit Care Med 2000 28(8):2991-6 [abstract]
Review, by D. Epstein R. Bart
2000-12-20THERAPYDelclaux C, L'Her E, Alberti C, , Treatment of Acute Hypoxemic Nonhypercapnic Respiratory Insufficiency With Continuous Positive Airway Pressure Delivered by a Face Mask: A Randomized Controlled Trial
JAMA 2000 284(18):2352-2360 [abstract] [Full-Text]
Review, by C. Davison
2000-12-18THERAPY/PREVENTIONDouzinas EE, Pitaridis MT, Louris G, , Prevention of infection in multiple trauma patients by high-dose intravenous immunoglobulins.
Crit Care Med 2000 28: 8-15 [abstract]
Review, by S. Bateman
2000-12-15DIAGNOSISHubble CL, Gentile MA, Tripp DS, Craig DM, Meliones JN Deadspace to tidal volume ratio predicts successful extubation in infants and children.
Crit Care Med 2000 28(6):2034-40 [abstract]
Review, by A. Torres
2000-12-06THERAPY/PREVENTIONPierce CM, Wade A, Mok Q, , Heparin-bonded central venous lines reduce thrombotic and infective complications in critically ill children.
Intensive Care Med 2000 26:967-972 [abstract]
Review, by J. Barron A. Madikians
2000-11-12PREDICTION TOOLKeenan HT, Bratton SL, Martin LD, Crawford SW, Weiss NS Outcome of children who require mechanical ventilatory support after bone marrow transplantation.
Crit Care Med 2000 28(3):830-5 [abstract]
Review, by X. Garcia H. Tcharmtchi
2000-10-27PREDICTION TOOLBaumeister BL, el-Khatib M, Smith PG, Blumer JL, Evaluation of predictors of weaning from mechanical ventilation in pediatric patients.
Pediatr Pulmonol 1997 24:344-52 [abstract]
Review, by S. Venkataraman
2000-10-20PROGNOSISRossi R, Shemie SD, Calderwood S, , Prognosis of pediatric bone marrow transplant recipients requiring mechanical ventilation.
Crit Care Med 1999 27:1181-6 [abstract]
Review, by J. Heggen J. Fortenberry
2000-10-13THERAPYBrower RG, Shanholtz CB, Fessler HE, , Prospective, randomized, controlled clinical trial comparing traditional versus reduced tidal volume ventilation in acute respiratory distress syndrome patients.
Crit Care Med 1999 27:1492-8 [abstract]
Review, by P. Prabhakaran
2000-10-07THERAPYLevin M, Quint PA, Goldstein B, , Recombinant bactericidal/permeability-increasing protein (rBPI21) as adjunctive treatment for children with severe meningococcal sepsis: a randomised trial.
Lancet 2000 356: 961 - 967 [abstract]
Review, by S. Cray
2000-10-07THERAPYPittet D, Harbarth S, Suter PM, , Impact of immunomodulating therapy on morbidity in patients with severe sepsis.
Am J Respir Crit Care Me 1999 160:852-7 [abstract] [Full-Text]
Review, by N. Cvijanovich
2000-09-25SYS-REVIEWGarrison MM, Christakis DA, Harvey E, Cummings P, Davis RL. Systemic Corticosteroids in Infant Bronchiolitis: A Meta-analysis
Pediatrics 2000 105:e44 [abstract] [Full-Text]
Review, by M. Bonnie Dutta
2000-09-22SURROGATE/THERAPY Varpula T, Pettila, Rintala E, Takkunen O, Valtonen Late steroid therapy in primary acute lung injury.
Intensive Care Med 2000 26:526-531 [abstract]
Review, by Narsinghani U. Heulitt M.
2000-09-21PREDICTION TOOLFarias JA, Alia I, Esteban A, Golubicki, Olazarri FA Weaning from mechanical ventilation in pediatric intensive care patients.
Intensive Care Med 1998 24: 1070-1075 [abstract]
Review, by P. Jines A. Madikians
2000-09-17PREDICTION TOOLAnnane D, S?bille V, Troch? G, , A 3-Level Prognostic Classification in Septic Shock Based on Cortisol Levels and Cortisol Response to Corticotropin.
JAMA 2000 283:1038-1045 [abstract] [Full-Text]
Review, by X. Garcia M. McPherson
2000-09-10THERAPYGausche M, Lewis RJ, Stratton SJ, , Effect of Out-of-Hospital Pediatric Endotracheal Intubation on Survival and Neurological Outcome: A Controlled Clinical Trial.
JAMA 2000 283:783-790 [abstract] [Full-Text]
Review, by J. Gregory K. Tegtmeyer
2000-09-08DECISION ANALYSISVeenstra DL, Saint S, Sullivan SD, , Cost-effectiveness of antiseptic-impregnated central venous catheters for the prevention of catheter-related bloodstream infection.
JAMA 1999 282:554-60 [abstract] [Full-Text]
Review, by M. K. Moynihan Hardart
2000-09-01THERAPYKress JP, Pohlman AS, O'Connor MF, Hall JB, Daily Interruption of Sedative Infusions in Critically Ill Patients Undergoing Mechanical Ventilation
N Engl J Med 2000 342:1471-1477 [abstract]
Review, by A. Torres
2000-08-21SYSTEMATIC REVIEWVeenstra DL, Saint S, Somnath S, Lumley T, Sullivan SD Efficacy of antiseptic-impregnated central venous catheters in preventing catheter-related bloodstream infection. A meta-analysis.
JAMA 1999 281:261-267 [abstract] [Full-Text]
Review, by M. K. Moynihan Hardart
2000-08-04THERAPYAlia I, Esteban A, Gordo F, , A randomized and controlled trial of the effect of treatment aimed at maximizing oxygen delivery in patients with severe sepsis or septic shock
Chest 1999 28(4):921-8 [abstract]
Review, by Prabhakaran P. Butler T.
2000-07-27SURROGATE/THERAPYIchai C, Soubielle J, Carles M, Giunti C, Grimaud D Comparison of the renal effects of low to high doses of dopamine and dobutamine in critically ill patients: a single-blind randomized study.
Crit Care Med 2000 283:235-241 [abstract] [Full-Text]
Review, by Narsinghani U.
2000-07-22THERAPYAntonelli M, Conti G, Bufi M, et al. Noninvasive Ventilation for Treatment of Acute Respiratory Failure in Patients Undergoing Solid Organ Transplantation; A Randomized Trial.
JAMA 2000 27:2799-805 [abstract]
Review, by P. Prabhakaran, M. Mariscalco
2000-06-30SYSTEMATIC REVIEWBeale RJ, Bryg DJ, Bihari DJ, , Immunonutrition in the critically ill: a systematic review of clinical outcome.
Crit Care Med 1999 27:2786-91 [abstract]
Review, by Azzam Maha
2000-06-02THERAPYLieh-Lai MW, Kauffman RE, Uy HG, Danjin M, Simpson PM. A randomized comparison of ketorolac tromethamine and morphine for postoperative analgesia in critically ill children.
Crit Care Med 1999 27:2782-5 [abstract]
Review, by J. Tuladhar
2000-05-09SURROGATE END POINTPretzlaff RK, Vardis RJ, Pollack MM, , Aminophylline in the treatment of fluid overload.
Crit Care Med 1999 342: 1301-1308 [abstract]
Review, by P Jines R Harrison
2000-04-28THERAPYAcute Respiratory Distress Syndrome Network, , , , Ventilation with Lower Tidal Volumes as Compared with Traditional Tidal Volumes for Acute Lung Injury and the Acute Respiratory Distress Syndrome.
N Engl J Med 2000 27:2331-6 [abstract]
Review, by Steven Cray
2000-04-14SYSTEMATIC REVIEWButler R, Keenan SP, Inman KJ, Sibbald WJ, Block G. Is there a preferred technique for weaning the difficult-to-wean patient? A systematic review of the literature.
Crit Care Med 1999 319:595-600 [abstract] [Full-Text]
Review, by A. Torres J. Wohrley
2000-04-03SYSTEMATIC REVIEWAusejo M, Saenz, Pham, , The effectiveness of glucocorticoids in treating croup: meta-analysis.
Br Med J 1999 8:491-9 [abstract]
Review, by Melchor Sanchez-Mendiola
2000-03-02HARMBray RJ, , , , Propofol infusion syndrome in children
Paed Anaesth 1998 160:829-34 [abstract] [Full-Text]
Review, by Steven Cray
2000-02-08THERAPYGuerguerian AM, Gauthier M, Lebel MH, Farrell CA, Lacroix J Ribavirin in ventilated respiratory syncytial virus bronchiolitis. A randomized, placebo-controlled trial.
Am J Respir Crit Care Me 1999 27:2096-104 [abstract]
Review, by P. Chalikonda MD
2000-02-04THERAPYReeves JH, Butt WW, Shann F, , Continuous plasmafiltration in sepsis syndrome. Plasmafiltration in Sepsis Study Group.
Crit Care Med 1999 20:17-21 [abstract]
Review, by Steven Cray
2000-02-02THERAPYSingh NC, Kissoon N, Mofada SA, Bennett M, Bohn DJ Comparison of continuous versus intermittent furosemide administration in postoperative pediatric cardiac patients
Crit Care Med 1992 27:1974-81 [abstract]
Review, by Patricia Jines Jonathan D. Feldman
2000-01-25PROGNOSISKhongphatthanayothin A, Wong PC, Samara Y, , Impact of respiratory syncytial virus infection on surgery for congenital heart disease: postoperative course and outcome.
Crit Care Med 1999 80: 163-166 [abstract] [Full-Text]
Review, by Christopher J. Babbitt MD Jonathan D. Feldman MD
2000-01-14DIAGNOSISTibby SM, Hatherill M, Murdoch IA, , Capillary refill and core-peripheral temperature gap as indicators of Hemodynamics status in paediatric intensive care patients
Arch Dis Child 1999 109: 1302-1312 [abstract]
Review, by Cray, Steven
1999-12-18SURROGATE/THERAPYBarton P, Garcia J, Kouatli A, Kitchen L, Zorka A Hemodynamic effects of i.v. milrinone lactate in pediatric patients with septic shock. A prospective, double-blinded, randomized, placebo-controlled, interventional study.
Chest 1996 27:723-32 [abstract]
Review, by Michael Verive, MD
1999-12-11SURROGATE/THERAPYBriegel J, Forst H, Haller M, , Stress doses of hydrocortisone reverse hyperdynamic septic shock: a prospective, randomized, double-blind, single-center study.
Crit Care Med 1999 27:1409-20 [abstract]
Review, by Vaughan David
1999-12-04SURROGATE/THERAPYEnteral Nutrition in ARDS Study Group., Gadek JE, DeMichele SJ, Karlstad MD, Effect of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in patients with acute respiratory distress syndrome
Crit Care Med 1999 27:989-96 [abstract]
Review, by Scot Bateman MD,
1999-11-18THERAPYReam RS, Hauver JF, Lynch RE, Kountzman B, Gale GB Low-dose inhaled nitric oxide improves the oxygenation and ventilation of infants and children with acute, hypoxemic respiratory failure
Crit Care Med 1999 158: 1831-1838 [abstract] [Full-Text]
Review, by Ron Sanders Jr., MD
1999-11-12THERAPY/PREVENTIONDarouiche RO, Raad II, Heard SO, , A comparison of two antimicrobial-impregnated central venous catheters.
N Engl J Med 1999 158:1770-1777 [abstract] [Full-Text]
Review, by Stephen Schexnayder MD
1999-11-11SURROGATE END POINTGallart L, Lu Q, Puybasset L, , Intravenous Almitrine Combined with Inhaled Nitric Oxide for Acute Respiratory Distress Syndrome
Am J Respir Crit Care Me 1998 27:807-14 [abstract]
Review, by Steven Cray
1999-11-02THERAPYLauterbach R, Pawlik D, Kowalczych D, , Effect of the immunomodulating agent, pentoxifylline, in the treatment of sepsis in prematurely delivered infants: a placebo-controlled, double-blind trial
Crit Care Med 1999 26:1977-85 [abstract]
Review, by Troy Dominguez MD,
1999-10-02THERAPYJolliet P, Bulpa P , Chevrolet JC, , Effects of the prone position on gas exchange and hemodynamics in severe acute respiratory distress syndrome.
Crit Care Med 1998 99:e11 [abstract] [Full-Text]
Review, by Varsha Gharpure, MD Kathleen Meert, MD
1999-09-28PREDICTION TOOLQuayle KS, Jaffe DM, Juppermann N, Kaufman BA, Lee BC Diagnostic Testing for Acute Head Injury in Children: When are Head Computed Tomography and Skull Radiographs Indicated?
Pediatrics 1997 340:409-417 [abstract]
Review, by Sahhar, Hanna
1999-09-12THERAPYHebert PC, Wells G, Blajchman MA, Marshall J, A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care.
N Engl J Med 1999 27:200-10 [abstract]
Review, by Fiona H. Levy MD, Barry Markovitz MD,
1999-08-23SYSTEMATIC REVIEWChoi PT, Yip G, Quinonez LG, Cook DJ, Crystalloids vs. colloids in fluid resuscitation: a systematic review.
Crit Care Med 1999 134:406-412 [abstract]
Review, by Melchor Sanchez-Mendiola,
1999-08-23THERAPYDobyns EL, Cornfield DN, Anas NG, Fortenberry JD, Tasker RC Multicenter randomized controlled trial of the effects of inhaled nitric oxide on gas exchange in children with acute hypoxemic respiratory failure.
J Pediatr 1999 159: 695-701 [abstract]
Review, by Al Torres, MD, MS,
1999-08-23SURROGATE/THERAPYDobyns EL, Cornfield DN, Anas NG, Fortenberry JD, Tasker RC Multicenter randomized controlled trial of the effects of inhaled nitric oxide therapy on gas exchange in children with acute hypoxemic respiratory failure.
J Pediatr 1999 79: 405-410 [abstract]
Review, by Faberowski L.
1999-07-09THERAPYHolzapfel L, Chastang C, Demingeon G, , A randomized study assessing the systematic search for maxillary sinusitis in nasotracheally mechanically ventilated patients. Influence of nosocomial maxillary sinusitis on the occurrence of ventilator-associated pneumonia
Am J Respir Crit Care Me 1999 26:645-650 [abstract]
Review, by Kshama Daphtary, MD Kathleen Meert, MD
1999-07-02THERAPYYung M, South M, , , Randomized controlled trial of aminophylline for severe acute asthma.
Arch Dis Child 1998 336: 597-604 [abstract]
Review, by Girish Deshpande, MD Kathleen Meert, MD
1999-06-27THERAPYBollaert PE, Charpentier C, Levy B, Debouverie M, Audibert G Reversal of late septic shock with supraphysiologic doses of hydrocortisone.
Crit Care Med 1998 26:645-650 [abstract]
Review, by Al Torres, MD, MS,
1999-06-27THERAPY/PREVENTIONBrochard L, Roudot-Thoraval F, Roupie E, , Tidal Volume Reduction for Prevention of Ventilator-induced Lung Injury in Acute Respiratory Distress Syndrome.
Am J Respir Crit Care Me 1998 150: 1166-1172 [abstract]
Review, by Graham Tse, MD,
1999-06-19THERAPYThe Neonatal Inhaled Nitric Oxide Group , , , , Inhaled nitric oxide in full term and nearly full term infants with hypoxic respiratory failure.
N Engl J Med 1997 1731-1736 [abstract]
Review, by P. Chhangani, MD J. Hupert, MD
1999-06-18SYSTEMATIC REVIEWKellner JD, Ohlsson A, Gadomski AM, Wang EE, Efficacy of Bronchodilator Therapy in Bronchiolitis: A Meta-analysis
Arch Pediatr Adolesc Med 1996 23:1294-303 [abstract]
Review, by Margarita Reloza-Macias, MD,
1999-06-12THERAPYHollman G, Shen G, Zeng L, , Helium-oxygen improves Clinical Asthma Scores in children with acute bronchiolitis
Crit Care Med 1998 280:159-165 [abstract]
Review, by Kate G. Ackerman, M.D.,
1999-06-11SYSTEMATIC REVIEWLefering R, Neugebauer E, , , Steroid controversy in sepsis and septic shock: A meta-analysis.
Crit Care Med 1995 27:188-95 [abstract]
Review, by Cheri Landers, MD,
1999-06-11THERAPYMeduri GU, Headley AS, Golden E, Carson SJ, Umberger RA Effect of prolonged methylprednisolone therapy in unresolving acute respiratory distress syndrome: a randomized controlled trial
JAMA 1998 317: 235-240 [Full-Text]
Review, by MIcheal Kelly MD Steven Pon, MD
1999-06-11THERAPYWillson DF, Zaritsky A, Bauman LA, , Instillation of calf lung surfactant extract (calfactant) is beneficial in pediatric acute hypoxemic respiratory failure
Crit Care Med 1999 316: 961-5 [abstract]
Review, by Poyyapakkam Srivaths M.D. Kathleen Meert, M.D.
1999-05-23SYSTEMATIC REVIEWCochrane Injuries Group Albumin Reviewers., , , , Human albumin administration in critically ill patients: systematic review of randomized controlled trials.
Br Med J 1998 150:942-947 [abstract]
Review, by Al Torres, MD, MS
1999-04-19SYSTEMATIC REVIEWRandolph AG, Wang EE, , , Ribavirin for Respiratory Syncytial Virus Lower Respiratory Tract Infection: A Systematic Overview
Arch Pediatr Adolesc Med 1996 158: 908-916 [abstract] [Full-Text]
Review, by Michael J. Verive, MD
1999-04-19SYSTEMATIC REVIEWSchierhout G, Roberts I, , , Fluid resuscitation with colloid or crystalloid solutions in critically ill patients: a systematic review of randomized trials
Br Med J 1998 26: 1265-1270 [abstract]
Review, by Michael J. Verive, MD
1999-03-09THERAPYSimma B, Burger R, Falk M, Sacher P , Fanconi S A prospective, randomized, and controlled study of fluid management in children with severe head injury: lactated Ringer's solution versus hypertonic saline
Crit Care Med 1998 157: 1483-1488 [abstract] [Full-Text]
Review, by Stephanie Sudikoff, MD
1999-03-05THERAPYSanchez Garcia MS, Cambronero Galache JA, Diaz JL, , Effectiveness and Cost of Selective Decontamination of the Digestive Tract in Critically Ill Intubated Patients. A randomized, double-blind, placebo-controlled, multicenter trial
Am J Respir Crit Care Me 1998 130:191-6 [abstract]
Review, by Paulette Johnson, MD Barry Markovitz, MD
1999-03-04THERAPYTroncy E, Collet JP, Shapiro S, Guimond JG, Blair L Inhaled Nitric Oxide in Acute Respiratory Distress Syndrome: A Pilot Randomized Controlled Study.
Am J Respir Crit Care Me 1998 339: 1030-35 [abstract]
Review, by Maher Eldadah MD
1999-03-03THERAPYKlassen TP, Sutcliffe TS, Watters LK, Wells Ga, Allen UD Dexamethasone in salbutamol-treated inpatients with acute bronchiolitis: A randomized, controlled trial
J Pediatr 1997 23: 1430-1439 [abstract]
Review, by Barry Markovitz, MD,
1999-01-21THERAPYQureshi F, Pestian J, Davis P, Zaritsky A, Effect of nebulized ipratropium bromide on the hospitalization rates of children with asthma.
N Engl J Med 1998 26:1164-1172 [abstract]
Review, by Al Torres, MD, MS G. Kris Bysani, MD
1999-01-17SYSTEMATIC REVIEWCronin L, Cook DJ, Carlet J, Heyland DK, King D Corticosteroids treatment for sepsis: a critical appraisal and meta-analysis of the literature
Crit Care Med 1995 338: 347-354 [abstract]
Review, by Varsha Gharpure, MD Kathleen Meert, MD,
1998-12-24THERAPYAtkinson S, Sieffert E, Bihari D, GuyŐ Hospital Intensive Care Group, A prospective, randomized, double-blind, controlled clinical trial of enteral immunonutrition in the critically ill
Crit Care Med 1998 2:651-656 [abstract]
Review, by Tom Brazelton, MD, MPH,
1998-12-14THERAPY/PREVENTIONAmato MBP, Barbas CSV, Medeiros DM, , Effect of a Protective-Ventilation Strategy on Mortality in the Acute Respiratory Distress Syndrome.
N Engl J Med 1998 101: 361-368 [abstract]
Review, by Kazuo Obata MD
1998-11-23SYSTEMATIC REVIEWOsmond MH, Klassen TP, , , Efficacy of ipratropium bromide in acute childhood asthma: a meta-analysis
Acad Emergency Med 1995 339:429-435 [abstract]
Review, by Al Torres, MD, MS
1998-11-19THERAPYDobson JV, Stephen-Groff SM, McMahon SR, Stemmler, Brallier SL The Use of Albuterol in Hospitalized Infants With Bronchiolitis
Pediatrics 1998 52: 634-637 [abstract]
Review, by Kshama Daphtary, MD Kathleen Meert, MD,
1998-10-06THERAPYAntonelli M, Conti G,, Rocco M, , Bufi M, De Blasi RA A comparison of noninvasive positive-pressure ventilation and conventional mechanical ventilation in patients with acute respiratory failure.
N Engl J Med 1998 157: 1372-1380 [abstract] [Full-Text]
Review, by Girish Deshpande, MD Kathleen Meert, MD
1998-09-29THERAPYvan Woensel JB, Wolfs TF, van Aalderen WM, Brand PL, Kimpen JL Randomized double blind placebo controlled trial of prednisolone in children admitted to hospital with respiratory syncytial virus bronchiolitis
Thorax 1997 15:579-583 [abstract]
Review, by Al Torres, M.D., M.S.
1998-09-04THERAPYMicheal JR, Barton RG, Saffle JR, , Inhaled Nitric Oxide Versus Conventional Therapy: Effect on Oxygenation in ARDS
Am J Respir Crit Care Me 1998 338: 355-361 [abstract]
Review, by Gerardo Reyes, M.D.
1998-08-19THERAPYSlusher T, Gbadero D, Howard C, Lewison L, Giroir B Randomized, placebo-controlled, double blinded trial of dexamethasone in African children with sepsis
Pediatr Infect Dis J 1996 338: 791-797 [abstract]
Review, by Mignon McCulloch, MD Max Klein, MD
1998-08-18THERAPYStewart TE, Meade MO, Cook DJ, , Evaluation of a Ventilation Strategy to Prevent Barotrauma in Patients at High Risk for Acute Respiratory Distress Syndrome
N Engl J Med 1998 26: 15-23 [abstract]
Review, by Mona McPherson MD Michele Mariscalo MD
1998-08-06THERAPYCook D, Guyatt G, Marshall J, , A Comparison of Sucralfate and Ranitidine for the Prevention of Upper Gastrointestinal Bleeding in Patients Requiring Mechanical Ventilation
N Engl J Med 1998 25:346-351 [abstract]
Review, by Scot T. Bateman, M.D
1998-06-15THERAPYDellinger RP, Zimmerman JL, Taylor RW, Straube RC, Hauser DL Effects of inhaled nitric oxide in patients with acute respiratory distress syndrome: results of a randomized phase II trial
Crit Care Med 1998 127:267-274 [abstract]
Review, by Scot Bateman, MD
1998-06-13THERAPYKuusela AL, Ruuska T, Karikoski R, Laippala P, Ilonen S A randomized controlled study of prophylactic Ranitidine in preventing stress-induced gastric mucosal lesions in neonatal intensive care unit patients.
Crit Care Med 1997 127:257-266 [abstract]
Review, by Girish Deshpande, MD Kathleen Meert, MD
1998-01-29THERAPYMaki DG, Stolz SM, Wheeler S, , Prevention of Central Venous Catheter-Related Bloodstream Infection by Use of an Antiseptic-Impregnated Catheter.
Ann Intern Med 1997 110: 1025-34 [abstract]
Review, by Stephen Schexnayder,
1998-01-29THERAPYRaad D, Darouiche ER, Dupuis J, , Central venous catheters coated with minocycline and rifampin for the prevention of catheter-related colonization and bloodstream infections.
Ann Intern Med 1997 314:1855-1859 [abstract]
Review, by Stephen Schexnayder
1997-09-02SYSTEMATIC REVIEWAlderson P, Roberts I. , , , Corticosteroids in acute traumatic brain injury: Systematic review of randomized controlled trials.
Br Med J 1997 314:1855-1859 [abstract]
Review, by Scot Bateman
1997-08-25THERAPYHarel Y, Vardi A, Quigley, B rink, Manning SC Extubation failure due to post-extubation stridor is better correlated with neurologic impairment than with upper airway lesions in critically ill pediatric patients
Int J Pediatr Otorhynolaryngal 1997 39: 147-158 [abstract]
Review, by Barry P. Markovitz
1997-07-29DECISION ANALYSISSterling T, Ho EJ, Brehm WT, Kirkpatrick MB, Diagnosis and treatment of ventilator-associated pneumonia--Impact on survival. A decision analysis.
Chest 1996 110: 1025-34 [abstract]
Review, by Adrienne Randolph
1997-05-27THERAPYCiarallo, L, Sauer AH, Shannon NW, , Intravenous magnesium therapy for moderate to severe pediatric asthma: Results of a randomized, placebo-controlled trial.
J Pediatr 1996 129: 809-14 [abstract]
Review, by Barry Markovitz
1997-05-15THERAPYMarion DW, Penrod LE, Kelsey SF, Obrist WD, Kochanek PM Treatment of traumatic brain injury with moderate hypothermia
N Engl J Med 1997 336: 540-546 [abstract]
Review, by Barry Markovitz, MD
1997-04-20THERAPYAnene O , Meert KL, Uy H, Simpson P, Sarmiak AP Dexamethasone for the prevention of postextubation airway obstruction: a prospective, randomized, double-blind, placebo-controlled trial.
Crit Care Med 1996 24: 1666-1669 [abstract]
Review, by Adrienne Randolph
1997-04-20THERAPYTellez DW, Galvis AG, Storgion SA, Amer HN, Hoseyni M Dexamethasone in the prevention of postextubation stridor in children.
J Pediatr 1991 118:289-294 [abstract]
Review, by Adrienne Randolph
1997-03-17PROGNOSISSchindler MB, Bohn D, Cox PN, McCrindle BW, Jarvis A Outcome of out-of-hospital cardiac or respiratory arrest in children.
N Engl J Med 1996 333:1473-9 [abstract]
Review, by Adrienne Randolph
1997-03-17THERAPYUK collaborative randomized trial of neonatal extracorporeal membrane oxygenation. , , , , UK collaborative randomized trial of neonatal extracorporeal membrane oxygenation.
Lancet 1996 348: 75-82 [abstract]
Review, by Adrienne Randolph
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