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| Date Posted | Article Type | Article Reviewed | Link and Reviewer(s) | | 435 Review(s) Found | | 2010-02-08 | SYSTEMATIC REVIEW | King VJ, Viswanathan M, Bordley WC, et al. Pharmacologic Treatment of Bronchiolitis in Infants and Children: A Systematic Review Arch Pediatr Adolesc Med 2004 ;158 127-137 [abstract] | Review, by Chloe Johnston MD, Imperial College Healthcare NHS Trust, London, UK | | 2010-02-05 | THERAPY/PREVENTION | Marelich GP, Murin S, Battistella F, Inciardi J, Vierra T, Roby M. Protocol Weaning of Mechanical Ventilation in Medical and Surgical Patients by Respiratory Care Practitioners and Nurses : Effect on Weaning Time and Incidence of Ventilator-Associated Pneumonia. Chest. 2000 ;118(2):459-467. [abstract] | Review, by Julia Mercer Niebauer MD, University of Alabama at Birmingham, AL | | 2010-02-05 | THERAPY | Choong K, Bohn D, Fraser DD, Gaboury I, Hutchison JS, Joffe AR, Litalien C, Menon K, McNamara P, Ward RE Vasopressin in Pediatric Vasodilatory Shock - A Multi-center Randomized Controlled Trial Am J Respir Crit Care Med 2009 180:632-639 [abstract] | Review, by Elora Hussain MD and Conrad Epting MD, Children’s Memorial Hospital, Northwestern University, Chicago, IL | | 2010-01-21 | SYSTEMATIC REVIEW | McCaffrey J, Farrell C, Whiting P, Dan A, Bagshaw SM, Delaney AP. Corticosteroids to prevent extubation failure: a systematic review and meta-analysis. Intensive Care Med 2009 Jun;35(6):977-86 [abstract] | Review, by Enrico Opocher MD, University Hospital of Padua, Italy | | 2010-01-21 | DIAGNOSTIC TEST | Simon L, Saint-Louis P, Amre DK, Lacroix J, Gauvin F. Procalcitonin and C-reactive protein as markers of bacterial infection in critically ill children at onset of systemic inflammatory response syndrome Pediatr Crit Care Med. 2008 9:407-413 [abstract] | Review, by Konstantine Xoinis MD, University of California, San Francisco | | 2010-01-05 | SYSTEMATIC REVIEW | Annane D, Bellissant E, Bollaert PE, Briegel J, Confalonieri M, De Gaudio R, Keh D, Kupfer Y, Oppert M, Merduri GU. Corticosteroids in the Treatment of Severe Sepsis and Septic Shock in Adults: A Systematic Review JAMA 2009 301:2362-2375. [abstract] | Review, by Lee Tosi MD, Childrens Hospital Los Angeles, Los Angeles CA | | 2009-12-22 | THERAPY | Payen D, Mateo J, Cavaillon JM, Fraisse F, Floriot C, Vicaut E; Hemofiltration and Sepsis Group of the Collège National de RĂ©animation et de MĂ©decine d Impact of continuous venovenous hemofiltration on organ failure during the early phase of severe sepsis: a randomized controlled trial. Crit Care Med 2009 Mar;37(3):803-10. [abstract] | Review, by Thomas Conlon MD, University of Pittsburgh/Children's Hospital of Pittsburgh, Pittsburgh PA | | 2009-12-03 | PROGNOSIS | Price JF, Mott AR, Dickerson HA, Jefferies JL, Nelson DP, Chang AC, O Worsening renal function in children hospitalized with decompensated heart failure: evidence for a pediatric cardiorenal syndrome? Pediatr Crit Care Med. 2008 9(3):279-84 [abstract] | Review, by Alvaro Orjuela MD, West Virginia University, Morgantown WV | | 2009-12-03 | PREDICTION TOOL | Post F, Weilemann LS, Messow CM, Sinning C, MĂĽnzel T B-type natriuretic peptide as a marker for sepsis-induced myocardial depression in intensive care patients. Crit Care Med 2008 36(11):3030-3037 [abstract] | Review, by Pooja Kulkarni MD, Columbia University Medical Center, New York NY | | 2009-12-03 | THERAPY | Rumbak MJ, Newton M, Truncale T, Schwartz SW, Adams JW, Hazard PB. A prospective, randomized, study comparing early percutaneous dilational tracheotomy to prolonged translaryngeal intubation (delayed tracheotomy) in critically ill medical patients Crit Care Med. 2004 Aug;32(8):1689-94. [abstract] | Review, by Muzamil Noorani MD, Baylor College of Medicine, Houston TX | | 2009-12-01 | DIAGNOSIS | Gauvin F, Dassa C, Chaibou M, Proulx F, Farrell CA, Lacroix J. Ventilator-associated pneumonia in intubated children: comparison of different diagnostic methods. Pediatr Crit Care Med. 2003 Oct;4(4):437-43. [abstract] | Review, by Kathryn Young MD, Medical College of Wisconsin and Children's Hospital of Wisconsin, Milwaukee, WI | | 2009-12-01 | PREDICTION TOOL | Khemani RG, Bart RD, Alonzo TA, Hatzakis G, Hallam D, Newth CJ. Disseminated intravascular coagulation score is associated with mortality for children with shock Intensive Care Med 2009 35(2):327-33 [abstract] | Review, by Bill Cutrer MD, Baylor College of Medicine and Texas Children's Hospital, Houston TX | | 2009-12-01 | SYSTEMATIC REVIEW | Meduri GU, Marik PE, Chrousos GP, Pastores SM, Arlt W, Beishuizen A, Bokhari F, Zaloga G, Annane D. Steroid treatment in ARDS: a critical appraisal of the ARDS network trial and the recent literature. Intensive Care Med 2008 34(1):61-9 [abstract] | Review, by Bonny Bardhan MD, Tom Spentzas MD, University of Tennessee at Memphis, LeBonheur Children's Hospital, Memphis TN | | 2009-11-18 | THERAPY | October TW, Hardart GE. Successful placement of postpyloric enteral tubes using electromagnetic guidance in critically ill children. Pediatr Crit Care Med. 2009 10(2):196-200. [abstract] | Review, by Cara Connolly MD, Beaumont Hospital, Dublin, Ireland | | 2009-11-18 | THERAPY | Scolnik D, Coates AL, Stephens D, et al. Controlled Delivery of High vs Low Humidity vs Mist Therapy for Croup in Emergency Departments: A Randomized Controlled Trial. JAMA 2006 ;295 1274-1280 [abstract] | Review, by Eddie Gordon MD, Baylor College of Medicine, Texas Children's Hospital, Houston TX | | 2009-10-21 | PREDICTION TOOL | Leteurtre S, Martinot A, Duhamel A, et al. Validation of the paediatric logistic organ dysfunction (PELOD) score: prospective, observational, multicentre study Lancet. 2003 Jul 19;362(9379):192-7 [abstract] | Review, by J. Davre McNally MD PhD, Children's Hospital of Eastern Ontario, Ottawa, Canada | | 2009-09-30 | THERAPY | Gueugniaud PV, David JS, Chanzy E, et al. Vasopressin and Epinephrine vs. Epinephrine Alone in Cardiopulmonary Resuscitation N Engl J Med 2008 359:21-30 [abstract] | Review, by Varsha Gharpure MD, Children’s Hospital of Pittsburgh | | 2009-09-30 | PROGNOSIS | Mhanna MJ, Zamel YB, Tichy CM, Super DM. The "air leak" test around the endotracheal tube, as a predictor of postextubation stridor, is age dependent in children Crit Care Med. 2002 ;30(12):2639-43. [abstract] | Review, by Mary G. Gaspers MD, Baylor College of Medicine, Houston TX | | 2009-09-14 | THERAPY | Hall JC, Dobb G, Hall J, de Sousa R, Brennan L, McCauley R. A prospective randomized trial of enteral glutamine in critical illness Intensive Care Med. 2003 Oct;29(10):1710-6 [abstract] | Review, by Ivie Esangbedo MD, Texas Children's Hospital, Baylor College of Medicine, Houston TX | | 2009-09-14 | HARM | Hoorn EJ, Geary D, Robb M, Halperin ML, Bohn D. Acute Hyponatremia Related to Intravenous Fluid Administration in Hospitalized Children: An Observational Study Pediatrics 2004 ;113 1279-1284 [abstract] | Review, by Paul Veldhouse MD, Jason Kane MD, Children's Memorial Hospital, Chicago IL | | 2009-08-16 | DIAGNOSIS | Le Monnier A, Carbonnelle E, Zahar JR, Le Bourgeois M, Abachin E, Quesne G, Varon E, Descamps P, De Blic J, Scheinmann P, Berche P, Ferroni A. Microbiological diagnosis of empyema in children: comparative evaluations by culture, polymerase chain reaction, and pneumococcal antigen detection in pleural fluids. Clin Infect Dis 2006 15;42(8):1135-40 [abstract] | Review, by Stephanie Grayson MD, West Virginia University, Morgantown, WV | | 2009-07-24 | META-ANALYSIS | Wan S, Quinlan DJ, Agnelli G, Eikelboom JW. Thrombolysis Compared With Heparin for the Initial Treatment of Pulmonary Embolism: A Meta-Analysis of the Randomized Controlled Trials. Circulation 2004 ;110 744-749 [abstract] | Review, by Mihaela Damian MD, Stanford University, Lucile Packard Children Hospital, Palo Alto CA | | 2009-07-16 | PREDICTION TOOL | Seear MD, Scarfe JC, Leblanc JG. Predicting major adverse events after cardiac surgery in children. Pediatr Crit Care Med. 2008 9:606-611 [abstract] | Review, by Julie D. Sparks PNP-BC, Adrea L. Leach PNP-BC, West Virginia University Hospital, Morgantown, WV | | 2009-07-13 | DIAGNOSIS | Kimberly HH, Shah S, Marill K, Noble V. Correlation of optic nerve sheath diameter with direct measurement of intracranial pressure Acad Emergency Med 2008 15(2):201-4. [abstract] | Review, by Muzamil Noorani MD, Baylor College of Medicine and Texas Children's Hospital, Houston, TX | | 2009-07-13 | THERAPY | The NICE-SUGAR Study Investigators. Intensive versus Conventional Glucose Control in Critically Ill Patients N Engl J Med 2009 360:1283-1297 [abstract] | Review, by Amanda Brooks MD, Northwestern/McGaw Medical Center, Children's Memorial Hospital, Chicago IL | | 2009-06-30 | PREDICTION TOOL | Esteban A, Alia I, Tobin MJ, et al. Effect of Spontaneous Breathing Trial Duration on Outcome of Attempts to Discontinue Mechanical Ventilation Am J Respir Crit Care Med 1999 ;159:512-518. [abstract] | Review, by M. Fares Albitar MD, Ikram Haque MD, Shands Hospital at the University of Florida, Gainesville, Florida | | 2009-06-30 | PROGNOSIS | Yung D, Widlitz AC, Rosenzweig EB, et al. Outcomes in Children With Idiopathic Pulmonary Arterial Hypertension Circulation 2004 ;110 660-665 [abstract] | Review, by Christoph Hornik MD, David Turner MD, Duke Children’s Hospital, Durham, North Carolina | | 2009-06-26 | PROGNOSIS | Knoester H, Bronner MB, Bos AP. Surviving pediatric intensive care: physical outcome after 3 months. Intensive Care Med 2008 34(6):1076-1082 [abstract] | Review, by Simon Li, MD and E. Vincent S. Faustino, MD, Yale University School of Medicine, New Haven, CT | | 2009-06-03 | THERAPY | Gray A, Goodacre S, Newby DE, Masson M, Sampson F, Nicholl J; 3CPO Trialists. Noninvasive ventilation in acute cardiogenic pulmonary edema. N Engl J Med 2008 359(2):142-51 [abstract] | Review, by Kimberly Baker DO and Michael Wilhelm MD, American Family Children’s Hospital at the University of Wisconsin Hospital and Clinics Madison, WI | | 2009-05-27 | THERAPY | Papazian L, Gainnier M, Marin V, et al. Comparison of prone positioning and high-frequency oscillatory ventilation in patients with acute respiratory distress syndrome. Crit Care Med. 2005 Oct;33(10):2162-71. [abstract] | Review, by Jonna Clark MD, Seattle Children's Hospital, Seattle WA | | 2009-05-25 | PREDICTION TOOL | Wratney AT, Benjamin DK Jr, Slonim AD, He J, Hamel DS, Cheifetz IM. The endotracheal tube air leak test does not predict extubation outcome in critically ill pediatric patients. Pediatr Crit Care Med. 2008 9:490-496 [abstract] [Full-Text] | Review, by Erin Reade MD MPH, Children's Hospital of Philadelphia, Philadelphia PA | | 2009-04-18 | THERAPY | Talmor D, Sarge T, Malhotra A, O Mechanical Ventilation Guided by Esophageal Pressure in Acute Lung Injury. N Engl J Med 2008 359:2095-104 [abstract] | Review, by Jane L. Di Gennaro MD, Seattle Children’s Hospital | | 2009-04-16 | PREDICTION | VallĂ©e F, Vallet B, Mathe O, Parraguette J, Mari A, Silva S, Samii K, Fourcade O, Genestal M. Central venous-to-arterial carbon dioxide difference: an additional target for goal-directed therapy in septic shock? Intensive Care Med 2008 34(12):2218-2225 [abstract] | Review, by Fong Lam MD, Baylor College of Medicine and Texas Children's Hospital, Houston TX | | 2009-04-14 | THERAPY | Yañez LJ, Yunge M, Emilfork M, Lapadula M, Alcántara A, Fernández C, Lozano J, Contreras M, Conto L, Arevalo C, Gayan A, Hernández F, Pedraza M, Feddersen M, Bejares M, Morales M, Mallea F, Glasinovic M, Cavada G. A prospective, randomized, controlled trial of noninvasive ventilation in pediatric acute respiratory failure. Pediatr Crit Care Med. 2008 9(5):484-9 [abstract] | Review, by Zainab Abdurrahman MD MMath, McMaster University, Hamilton, Ontario, Canada | | 2009-04-06 | PROGNOSIS | Markovitz BP, Goodman DM, Watson RS, Bertoch D, Zimmerman J. A retrospective cohort study of prognostic factors associated with outcome in pediatric severe sepsis: what is the role of steroids? Pediatr Crit Care Med. 2005 6(3):270-4. [abstract] | Review, by Matthew Borgman MD, Children's Hospital Boston, Boston MA | | 2009-03-20 | THERAPY | Meade MO, Cook Dj, Guyatt GH, et al. for the Lung Open Ventilation Study Investigators. Ventilation Strategy Using Low Tidal Volumes, Recruitment Maneuvers, and High Positive End-Expiratory Pressure for Acute Lung Injury and Acute Respiratory Distress Syndrome: A Randomized Controlled Trial JAMA 2008 299 637-645 [abstract] | Review, by Carlos Acuna MD, Antonio Cabrera MD, Le Bonheur Children’s Medical Center, University of Tennessee, Memphis, TN | | 2009-03-20 | PROGNOSIS | Knoester H, Sol JJ, Ramsodit P, et al. Cardiac Function in Pediatric Septic Shock Survivors. Arch Pediatr Adolesc Med 2008 162:1164-1168 [abstract] | Review, by Simon Li MD, Yale University, New Haven CT | | 2009-03-20 | PROGNOSIS | LĂłpez-Herce J, Santiago MJ, Sánchez C, MencĂa S, Carrillo A, Vigil D. Risk factors for gastrointestinal complications in critically ill children with transpyloric enteral nutrition. Eur J Clin Nutr 2008 62(3):395-400 [abstract] | Review, by Victoria Sheward MB BS, Tanja Adamovic MD, Royal Brompton Hospital, London, UK | | 2009-02-23 | THERAPY | The VA/NIH Acute Renal Failure Trial Network. Intensity of Renal Support in Critically Ill Patients with Acute Kidney Injury. N Engl J Med 2008 359:7-20. [abstract] | Review, by Derek S. Wheeler MD, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH | | 2009-02-17 | SYSTEMATIC REVIEW | Duffett M, Choong K, Ng V, Randolph A, Cook DJ. Surfactant therapy for acute respiratory failure in children: a systematic review and meta-analysis. Critical Care 2007 15;11(3):R66 [abstract] | Review, by Matei Petrescu MD, Tulane School of Medicine, New Orleans LA | | 2009-01-22 | PROGNOSIS | Tamburro RF, Barfield RC, Shaffer ML, Rajasekaran S, Woodard P, Morrison RR, Howard SC, Fiser RT, Schmidt JE, Sillos EM. Changes in outcomes (1996-2004) for pediatric oncology and hematopoietic stem cell transplant patients requiring invasive mechanical ventilation. Pediatr Crit Care Med. 2008 9(3):270-7. [abstract] | Review, by Christine Vohwinkel MD, Denise Goodman MD, Children’s Memorial Hospital, Northwestern University, Chicago IL | | 2009-01-15 | PREDICTION TOOL | Millar KJ, Thiagarajan RR, Laussen PC. Glucocorticoid therapy for hypotension in the cardiac intensive care unit. Pediatr Cardiol 2007 28(3):176-82 [abstract] | Review, by RE Kirsch MD, L Zorzela MD, D Garros MD, University of Alberta, Stollery Children | | 2009-01-15 | THERAPY | Hutchison JS, Ward RE, Lacroix J, et al. for the Hypothermia Pediatric Head Injury Trial Investigators andt the Canadian Critical Care Trials Group. Hypothermia Therapy after Traumatic Brain Injury in Children. N Engl J Med 2008 358; 2447-2456. [abstract] | Review, by Thomas Arnold MD, University of California San Francisco | | 2009-01-15 | THERAPY/PREVENTION | Montañana PA, I Alapont VM, OcĂłn AP, LĂłpez PO, Prats JL, Parreño JD. The use of isotonic fluid as maintenance therapy prevents iatrogenic hyponatremia in pediatrics: A randomized, controlled open study. Pediatr Crit Care Med. 2008 9(6):589-597 [abstract] [Full-Text] | Review, by Rojjanee Lertbunrian MD, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand | | 2008-12-24 | PREDICTION TOOL | Kumar A, Roberts D, Wood KE, et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med 2006 34(6):1589-96 [abstract] | Review, by Thomas Conlon MD, University of Pittsburgh Medical Center/Children’s Hospital of Pittsburgh of UPMC | | 2008-12-24 | Technology Assessment | Knirsch W, Kretschmar O, Tomaske M, Stutz K, Nagdyman N, Balmer C, Schmitz A, BĂ©ttex D, Berger F, Bauersfeld U, Weiss M. Cardiac output measurement in children: comparison of the Ultrasound Cardiac Output Monitor with thermodilution cardiac output measurement. Intensive Care Med 2008 34(6):1060-1064 [abstract] | Review, by Jagdish Ambwani MD, Newark Beth Israel Medical Center, New Jersey | | 2008-12-11 | THERAPY | Mercat A, Richard J-C M, Vielle B, et al. for the Expiratory Pressure (Express) Study Group Positive End-Expiratory Pressure Setting in Adults With Acute Lung Injury and Acute Respiratory Distress Syndrome: A Randomized Controlled Trial. JAMA 2008 299 646-655 [abstract] | Review, by Aveek Jayant, Postdoctoral student, Dept of Anaesthesiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Medical College PO, Thiruvananthapuram, India | | 2008-12-08 | THERAPY/PREVENTION | Kollef MH, Afessa B, Anzueto A, et al. for the NASCENT Investigation Group Silver-Coated Endotracheal Tubes and Incidence of Ventilator-Associated Pneumonia: The NASCENT Randomized Trial JAMA 2008 300(7):805-813 [abstract] | Review, by Guruprasad T. Mahadevaiah MD and Sameer Gupta MD, University of Minnesota Children’s Hospital, Fairview MN | | 2008-12-01 | THERAPY | Honeycutt TC, El Khashab M, Wardrop RM 3rd, McNeal-Trice K, Honeycutt AL, Christy CG, Mistry K, Harris BD, Meliones JN, Kocis KC. Probiotic administration and the incidence of nosocomial infection in pediatric intensive care: a randomized placebo-controlled trial. Pediatr Crit Care Med. 2007 8(5):452-8 [abstract] | Review, by Samantha Gee MD, University of Florida College of Medicine, Shand's Children's Hospital, Gainesville FL | | 2008-11-12 | PREDICTION TOOL | Fontela PS, Piva JP, Garcia PC, Bered PL, Zilles K. Risk factors for extubation failure in mechanically ventilated pediatric patients. Pediatr Crit Care Med. 2005 Mar;6(2):166-170. [abstract] | Review, by Julianne Harrison DO, Myke Federman MD, Mattel Children’s Hospital UCLA, Los Angeles CA | | 2008-11-10 | THERAPY | Parienti JJ, Thirion M, MĂ©garbane B, et al; Members of the Cathedia Study Group. Femoral vs jugular venous catheterization and risk of nosocomial events in adults requiring acute renal replacement therapy: a randomized controlled trial. JAMA 2008 28;299(20):2413-22. [abstract] | Review, by Srinivas Murthy MD CM, Children's Hospital Boston and Harvard Medical School | | 2008-11-03 | SYS-REVIEW | Kreymann KG, de Heer G, Nierhaus Z, Kluge S. Use of polyclonal immunoglobulins as adjunctive therapy for sepsis or septic shock. Crit Care Med. 2007 35:2677-2685 [abstract] | Review, by Rahul Bhatia MD, AI duPont Hospital Children, Thomas Jefferson University, Wilmington, DE | | 2008-10-31 | THERAPY | Nava S, Gregoretti C, Fanfulla F, et al. Noninvasive ventilation to prevent respiratory failure after extubation in high-risk patients Crit Care Med. 2005 Nov;33(11):2465-2470. [abstract] | Review, by Pamela Hilvers MD, Robyn Schultz MD, WVU Children’s Hospital, Morgantown, WV | | 2008-10-21 | THERAPY | Perkins GD, McAuley DF, Thickett DR, Gao F. The Beta Agonist Lung Injury Trial (BALTI) a randomised placebo controlled clinical trial. Am J Respir Crit Care Med. 2006 ;173 281-287 [abstract] | Review, by Matei Petrescu, MD, Baylor College of Medicine, Texas Children's Hospital, Houston TX | | 2008-10-21 | THERAPY | Martin CM, Doig GS, Heyland DK, et al. Multicentre, cluster-randomized clinical trial of algorithms for critical-care enteral and parenteral therapy (ACCEPT) Can Med Assoc J 2004 ;170 197-204. [abstract] | Review, by Kim Ngo MD, Christopher Babbitt MD, Miller Children's Hospital, Long Beach CA | | 2008-09-11 | PROGNOSIS | Jayashree M, Singhi S. Diabetic ketoacidosis: Predictors of outcome in a pediatric intensive care unit of a developing country. Pediatr Crit Care Med. 2004 Sep;5(5):427-33. [abstract] | Review, by Paul Bauer MD, Medical College of Wisconsin | | 2008-09-11 | PREDICTION TOOL | Tissieres P, da Cruz E, Habre W, Aggoun Y, Mensi N, Kalangos A, Beghetti M. Value of brain natriuretic peptide in the perioperative follow-up of children with valvular disease. Intensive Care Med 2008 34(6):1109-13 [abstract] | Review, by Jagdish Ambwani MD, Newark Beth Israel Medical Center, New Jersey | | 2008-09-10 | PROGNOSIS | Andreasen JB, Johnsen SP, Ravn HB. Junctional ectopic tachycardia after surgery for congenital heart disease in children. Intensive Care Med 2008 34(5):895-902 [abstract] | Review, by Joel A. Reyes DO, USAF MC, University of Texas Health Science Center at San Antonio | | 2008-09-09 | THERAPY | Nguyen NQ, Chapman MJ, Fraser RJ, Bryant LK, Holloway RH. Erythromycin is more effective than metoclopramide in the treatment of feed intolerance in critical illness. Crit Care Med 2007 35(2):483-9. [abstract] | Review, by Erin Reade MD, Children's Hospital of Philadelphia | | 2008-08-29 | THERAPY | de Oliveira CF, de Oliveira DS, Gottschald AF, Moura JD, Costa GA, Ventura AC, Fernandes JC, Vaz FA, Carcillo JA, Rivers EP, Troster EJ. ACCM/PALS haemodynamic support guidelines for paediatric septic shock: an outcomes comparison with and without monitoring central venous oxygen saturation. Intensive Care Med 2008 34(6):1065-75 [abstract] | Review, by Robinder G. Khemani MD MsCI, Childrens Hospital Los Angeles, USC Keck School of Medicine | | 2008-08-29 | PREDICTION TOOL | Huang SC, Wu ET, Chen YS, Chang CI, Chiu IS, Wang SS, Lin FY, Ko WJ. Extracorporeal membrane oxygenation rescue for cardiopulmonary resuscitation in pediatric patients. Crit Care Med 2008 36(5):1607-13 [abstract] | Review, by Brian Joy MD and Jason M. Kane MD, Northwestern University Feinberg School of Medicine, Children's Memorial Hospital | | 2008-08-15 | DIAGNOSTIC TECH | Nagdyman N, Fleck T, Schubert S, et al. Comparison between cerebral tissue oxygenation index measured by near-infrared spectroscopy and venous jugular bulb saturation in children. Intensive Care Med. 2005 Jun;31(6):846-50 [abstract] | Review, by Carlos Acuna MD, Antonio Cabrera MD, Le Bonheur Children’s Medical Center, University of Tennessee, Memphis, TN | | 2008-08-13 | THERAPY | National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. Comparison of two fluid-management strategies in acute lung injury N Engl J Med 2006 354(24):2564-75 [abstract] | Review, by Mary G. Gaspers MD, Baylor College of Medicine, Texas Children's Hospital, Houson TX | | 2008-08-08 | THERAPY | Russell JA, Walley KR, Singer J, et al. for the VASST Investigators. Vasopressin versus norepinephrine infusion in patients with septic shock N Engl J Med. 2008 358:877-87 [abstract] | Review, by Samuel Umaru MD, Nicolas Rivera MD, Baylor College of Medicine and Texas Children | | 2008-07-24 | PROGNOSIS | Yung M, Wilkins B, Norton L, Slater A, for the Paediatric Study Group; Australian and New Zealand Intensive Care Society. Glucose control, organ failure, and mortality in pediatric intensive care Pediatr Crit Care Med. 2008 9(2):147-152 [abstract] [Full-Text] | Review, by Sunali Goyal MBBS, Punkaj Gupta MBBS and Natan Noviski MD, Massachusetts General Hospital, Boston MA | | 2008-07-16 | THERAPY | Honrubia T, Garcia Lopez FJ, et al. Noninvasive vs conventional mechanical ventilation in acute respiratory failure: a multicenter, randomized controlled trial. Chest. 2005 Dec;128(6):3916-24. [abstract] | Review, by Matei Petrescu MD, Baylor College of Medicine, Texas Children's Hospital, Houston TX | | 2008-07-16 | THERAPY | Piccinni P, Dan M, Barbacini S, et al. Early isovolaemic haemofiltration in oliguric patients with septic shock. Intensive Care Med. 2006 Jan;32(1):80-6 [abstract] | Review, by Derek S. Wheeler MD, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH | | 2008-07-16 | PREDICTION | Dyke PC 2nd, Yates AR, Cua CL, Hoffman TM, Hayes J, Feltes TF, Springer MA, Taeed R. Increased calcium supplementation is associated with morbidity and mortality in the infant postoperative cardiac patient Pediatr Crit Care Med. 2007 8(3):254-7 [abstract] | Review, by David F. Adams MD; Kshitij Mistry MD MSc, Duke Children’s Hospital, Durham NC | | 2008-07-07 | PROGNOSIS | Fiser RT, West NK, Bush AJ, Sillos EM, Schmidt JE, Tamburro RF. Outcome of severe sepsis in pediatric oncology patients. Pediatr Crit Care Med. 2005 Sep;6(5):531-536. [abstract] [Full-Text] | Review, by Danny Castro DO, Baylor College of Medicine, Texas Children | | 2008-07-07 | THERAPY | Brunkhorst FM, Engel C, Bloos F, et al., for the German Competence Network Sepsis (SepNet). Intensive Insulin Therapy and Pentastarch Resuscitation in Severe Sepsis. N Engl J Med 2008 358:125-139. [abstract] | Review, by Tara Neumayr MD, Washington University, St. Louis, MO | | 2008-06-19 | THERAPY | Pandharipande PP, Pun BT, Herr DL, et al. Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial. JAMA 2007 298(22):2644-53. [abstract] | Review, by Nicolas B Rivera MD, Baylor College of Medicine and Texas Children's Hospital, Houston, TX | | 2008-06-11 | THERAPY | Werdan K, Pilz G, Bujdoso O, et al., for the Score-Based Immunoglobulin Therapy of Sepsis (SBITS) Study Group Score-based immunoglobulin G therapy of patients with sepsis: The SBITS study. Crit Care Med. 2007 35:2693-2701 [abstract] | Review, by William Cutrer MD, Baylor College of Medicine, Texas Children's Hospital, Houston TX | | 2008-06-10 | THERAPY | Kuzik BA, Al-Qadhi SA, Kent S, Flavin MP, Hopman W, Hotte S, Gander S. Nebulized hypertonic saline in the treatment of viral bronchiolitis in infants. J Pediatr. 2007 151(3):266-70, 270.e1 [abstract] | Review, by Shadi Malaeb MD and Scot Bateman MD, University of Massachusetts Medical School | | 2008-05-31 | THERAPY | Sprung CL, Annane D, Keh D, et al., for the CORTICUS Study Group. Hydrocortisone Therapy for Patients with Septic Shock. N Engl J Med 2008 358:111-124 [abstract] | Review, by Brian C. Bridges MD, Children | | 2008-05-04 | ECONOMIC ANALYSIS | Thomas NJ, Hollenbeak CS, Lucking SE, Willson DF. Cost-effectiveness of exogenous surfactant therapy in pediatric patients with acute hypoxemic respiratory failure. Pediatr Crit Care Med. 2005 Mar;6(2):160-165. [abstract] | Review, by Mahesh Sharman MD, Paula Silva MD, Hurley Medical Center and Michigan State University, Flint, MI | | 2008-04-30 | THERAPY | Nadel S, Goldstein B, Williams MD, Dalton H, Peters M, Macias WL, Abd-Allah SA, Levy H, Angle R, Wang D, Sundin DP, Giroir B REsearching severe Sepsis and Organ dysfunction in children: a gLobal perspective (RESOLVE) study group. Drotrecogin alfa (activated) in children with severe sepsis: a multicentre phase III randomised controlled trial. Lancet. 2007 369(9564):836-43 [abstract] | Review, by Kimberly Baker MD, American Family Children's Hospital, University of Wisconsin, Madison, WI | | 2008-04-16 | THERAPY/PREVENTION | Cheng KC, Hou CC, Huang HC, Lin SC, Zhang H. Intravenous injection of methylprednisolone reduces the incidence of postextubation stridor in intensive care unit patients. Crit Care Med. 2006 ; 34(5):1345-1350. [abstract] | Review, by Julianne Harrison DO, Myke Federman MD, Mattel Children’s Hospital at UCLA, Los Angeles CA | | 2008-04-16 | THERAPY/PREVENTION | Garrel D, Patenaude J, Nedelec B, et al. Decreased mortality and infectious morbidity in adult burn patients given enteral glutamine supplements: A prospective, controlled, randomized clinical trial. Crit Care Med. 2003 Oct;31(10):2444-9. [abstract] | Review, by Jama Sy MD, Texas Children's Hospital and Baylor College of Medicine, Houston TX | | 2008-04-16 | PROGNOSIS | Casartelli CH, Garcia PC, Branco RG, Piva JP, Einloft PR, Tasker RC. Adrenal response in children with septic shock. Intensive Care Med 2007 33(9):1609-13 [abstract] | Review, by Penelope Sandiford MD, Children’s Hospital of Michigan, Detroit MI | | 2008-04-05 | HARM | Khan H, Belsher J, Yilmaz M, Afessa B, Moore SB, Hubmayr RD, Gajic O. Fresh frozen plasma and platelet transfusions are associated with development of acute lung injury in critically ill medical patients. Chest 2007 131:1308-1314 [abstract] | Review, by Robert A. Niebler MD, Medical College of Wisconsin, Milwaukee, WI | | 2008-04-03 | META-ANALYSIS | Zurcher M, Tramer MR, Walder B. Colonization and Bloodstream Infection with Single- Versus Multi-Lumen Central Venous Catheters: A Quantitative Systematic Review Anesth Analg 2004 ;99 177-182. [abstract] | Review, by by John S Giuliano Jr MD, Derek S Wheeler MD, Cincinnati Children’s Medical Center, Cincinnati OH | | 2008-04-03 | THERAPY | The SAFE Study Investigators Saline or Albumin for Fluid Resuscitation in Patients with Traumatic Brain Injury. N Engl J Med. 2007 357:874-884 [abstract] | Review, by Nicolas Rivera MD and M Michelle Mariscalco MD, Baylor College of Medicine and Texas Children’s Hospital, Houston, TX | | 2008-04-03 | PREDICTION TOOL | Howell MD, Donnino M, Clardy P, Talmor D, Shapiro NI. Occult hypoperfusion and mortality in patients with suspected infection. Intensive Care Med 2007 33(11):1892-9 [abstract] | Review, by Sunali Goyal MBBS (SERI), Punkaj Gupta, MBBS (MGH), Harvard Medical School, Boston | | 2008-04-03 | THERAPY | Sharek PJ, Parast LM, Long K, Coombs J, Earnest K, Sullivan J, Frankel LR, Roth SJ. Effect of a Rapid Response Team on Hospital-wide Mortality and Code Rates Outside the ICU in a Children JAMA 2007 298 2267-2274 [abstract] | Review, by Jennifer Plant MD, University of California San Francisco and Children’s Hospital and Research Center Oakland | | 2008-03-04 | THERAPY | Meduri GU, Golden E, Freire AX, Taylor E, Zaman M, Carson SJ, Gibson M, Umberger R. Methylprednisolone infusion in early severe ARDS: results of a randomized controlled trial. Chest 2007 131(4):954-63. [abstract] | Review, by Jennifer R Foster MD FRCPC, Children’s Hospital of Eastern Ontario | | 2008-02-06 | SYSTEMATIC REVIEW | Safdar N, Said A, Gangnon RE, Maki DG. Risk of Hemolytic Uremic Syndrome After Antibiotic Treatment of Escherichia coli O157:H7 Enteritis. A Meta-analysis JAMA 2002 ; 288:996-1001. [abstract] | Review, by Jama Sy MD, Texas Children | | 2008-01-31 | PREDICTION TOOL | Flori HR, Glidden DV, Rutherford GW, Matthay MA. Pediatric Acute Lung Injury: Prospective Evaluation of Risk Factors Associated with Mortality Am J Respir Crit Care Med. 2005 171(9):995-1001 [abstract] | Review, by Jeffrey J. Fanning MD, Medical College of Wisconsin, Milwaukee, WI | | 2008-01-31 | THERAPY | Martin GS, Moss M, Wheeler AP, Mealer M, Morris JA, Bernard GR. A randomized, controlled trial of furosemide with or without albumin in hypoproteinemic patients with acute lung injury. Crit Care Med. 2005 Aug;33(8):1681-1687. [abstract] | Review, by Robert B. Kelly MD, Irwin K. Weiss MD, Mattel Children’s Hospital at UCLA, Los Angeles, CA | | 2008-01-21 | META-ANALYSIS | Sackner-Bernstein JD, Kowalski M, Fox M, Aaronson K. Short-term risk of death after treatment with nesiritide for decompensated heart failure: a pooled analysis of randomized controlled trials. JAMA. 2005 Apr 20;293(15):1900-5. [abstract] | Review, by Anne Marie Yered MD, Children's Hospital of Michigan, Detroit MI | | 2008-01-21 | PREDICTION TOOL | Robinson LR, Micklesen PJ, Tirschwell DL, Lew HL. Predictive value of somatosensory evoked potentials for awakening from coma Crit Care Med. 2003 Mar;31(3):960-7. [abstract] | Review, by Nadeem Shafi MD, University of Florida, Gainesville FL | | 2007-12-26 | HARM | Kneyber MC, Hersi MI, Twisk JW, Markhorst DG, Plotz FB. Red blood cell transfusion in critically ill children is independently associated with increased mortality Intensive Care Med 2007 33(8):1414-22 [abstract] | Review, by LM Zorzela MD, R Kirsh MD, G Guerra MD, AR Joffe MD; Stollery Children | | 2007-12-18 | THERAPY | Houdijk AP, Rijnsburger ER, Jansen J, et al. Randomised trial of glutamine-enriched enteral nutrition on infectious morbidity in patients with multiple trauma Lancet. 1998 5;352(9130):772-6. [abstract] | Review, by Jama Sy MD, Texas Children's Hospital and Baylor College of Medicine, Houston TX | | 2007-12-18 | THERAPY | Lacroix J, Hebert PC, Hutchison, et al. Transfusion Strategies for Patients in Pediatric Intensive Care Units N Engl J Med 2007 356:1609-1619 [abstract] | Review, by Eloa S Adams MD, Lucile Packard Children's Hospital, Stanford University School of Medicine, Palo Alto, CA | | 2007-12-14 | THERAPY | Berens RJ, Meyer MT, Mikhailov TA, et al. A Prospective Evaluation of Opioid Weaning in Opioid-Dependent Pediatric Critical Care Patients. Anesth Analg 2006 ;102 1045-1050 [abstract] | Review, by Katherine M Pleacher MD, Susan L Bratton MD MPH, University of Utah, Salt Lake City, UT | | 2007-12-14 | THERAPY | Fineman LD, LaBrecque M, Shih M-C, Curley MA Prone positioning can be safely performed in critically ill infants and children Pediatr Crit Care Med. 2006 7: 413-22 [abstract] | Review, by Mark D Weber RN PCCNP, Duke University Medical Center, Durham, NC | | 2007-12-13 | PROGNOSIS | Henzler D, Cooper DJ, Tremayne AB, Rossaint R, Higgins A. Early modifiable factors associated with fatal outcome in patients with severe traumatic brain injury: a case control study. Crit Care Med 2007 35(4):1027-31 [abstract] | Review, by S. David McSwain MD MPH, Duke University Medical Center, Durham NC | | 2007-11-28 | PREDICTION TOOL | Lawrence SE, Cummings EA, Gaboury I, Daneman D. Population-based study of incidence and risk factors for cerebral edema in pediatric diabetic ketoacidosis. J Pediatr. 2005 May;146(5):688-92. [abstract] | Review, by Girish Deshpande MD, Adelberto Torres MD, University of Illinois, Peoria IL | | 2007-11-17 | THERAPY | Ferrer M, Valencia M, Nicolas JM, Bernadich O, Badia JR, Torres A. Early noninvasive ventilation averts extubation failure in patients at risk: a randomized trial Am J Respir Crit Care Med. 2006 Jan 15;173(2):164-70. [abstract] | Review, by Punkaj Gupta MD, Natan Noviski MD, Massachusetts General Hospital, Boston MA | | 2007-11-17 | PROGNOSIS | Jones S, Rantell K, Stevens K et al. on behalf of the United Kingdom Pediatric Intensive Care Outcome Study Group. Outcome at 6 Months After Admission for Pediatric Intensive Care: A Report of a National Study of Pediatric Intensive Care Units in the United Kingdom. Pediatrics 2006 118 2101-2108 [abstract] | Review, by Katri Typpo MD MPH, Baylor College of Medicine, Texas Children | | 2007-11-17 | PREDICTION TOOL | Jeschke MG, Chinkes DL, Finnerty CC, et al. Blood transfusions are associated with increased risk for development of sepsis in severely burned pediatric patients. Crit Care Med 2007 35(2):579-83 [abstract] | Review, by Kathryn Young MD, Medical College of Wisconsin, Children | | 2007-10-12 | HARM | Hoorn EJ, Carlotti AP, Costa LA, MacMahon B, Bohn G, Zietse R, Halperin ML, Bohn D. Preventing a drop in effective plasma osmolality to minimize the likelihood of cerebral edema during treatment of children with diabetic ketoacidosis. J Pediatr 2007 150(5):467-73 [abstract] | Review, by Robert B. Kelly MD and Andranik Madikians, MD, Mattel Children’s Hospital at UCLA, Los Angeles, CA | | 2007-10-06 | PROGNOSIS | Sarthi M, Lodha R, Vivekanandhan S, Arora NK. Adrenal status in children with septic shock using low-dose stimulation test Pediatr Crit Care Med. 2007 8:23-28. [abstract] [Full-Text] | Review, by G Garcia Guerra MD, L Zorzela MD, R Kirsch MD, Stollery Children | | 2007-10-06 | SYSTEMATIC REVIEW | Villatoro E, Bassi C, Larvin M. Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis. Cochrane Review 2006 (4):CD002941 [abstract] | Review, by Edwin Taylor MD, West Virginia University, Morgantown, WV | | 2007-10-02 | PROGNOSIS | Cremer OL, van Dijk GW, van Wensen E, Brekelmans GJ, Moons KG, Leenen LP, Kalkman CJ. Effect of intracranial pressure monitoring and targeted intensive care on functional outcome after severe head injury. Crit Care Med. 2005 Oct;33(10):2207-2213. [abstract] | Review, by Meredith Bone MD, Children’s Memorial Hospital, Northwestern University, Chicago, IL | | 2007-09-19 | THERAPY | Wiedermann CJ, Hoffmann JN, et al.; for the KyberSept Investigators. High-dose antithrombin III in the treatment of severe sepsis in patients with a high risk of death: Efficacy and safety. Crit Care Med. 2006 Feb;34(2):285-292. [abstract] | Review, by Nicolas Rivera MD and Mona McPherson MD, Baylor College of Medicine and Texas Children | | 2007-09-10 | PROGNOSIS | Liet JM, Paranon S, Baraton L, Dejode JM, Roze JC. Is a prophylactic treatment by erythropoietin relevant to reduce red blood cell transfusion in the pediatric intensive care unit? Pediatric Critical Care Medicine 2006 7(6):541-4. [abstract] | Review, by Joel A. Reyes DO, US Air Force and Texas Children’s Hospital/Baylor College of Medicine | | 2007-08-23 | THERAPY | Huang CJ, Lin HC. Association between adrenal insufficiency and ventilator weaning. Am J Respir Crit Care Med. 2006 Feb 1;173(3):276-80. [abstract] | Review, by Christine Agee, CPNP-AC/PC, Duke University Medical Center, Durham, NC | | 2007-08-18 | DIAGNOSIS | Rey C, Los Arcos M, Concha A, et al. Procalcitonin and C-reactive protein as markers of systemic inflammatory response syndrome severity in critically ill children. Intensive Care Med 2007 33(3):477-84 [abstract] | Review, by Punkaj Gupta MD, Massachusetts General Hospital, Boston MA | | 2007-08-14 | THERAPY | Mayer SA, Brun NC, Begtrup K, Broderick J, Davis S, Diringer MN, Skolnick BE, Steiner T; Recombinant Activated Factor VII Intracerebral Hemorrhage Trial Investigators. Recombinant activated factor VII for acute intracerebral hemorrhage. N Engl J Med. 2005 Feb 24;352(8):777-85 [abstract] | Review, by Vikas Shah MD, Cornell University, New York, NY | | 2007-07-20 | DIAGNOSIS | Rey C, Los Arcos M, Concha A, et al. Procalcitonin and C-reactive protein as markers of systemic inflammatory response syndrome severity in critically ill children. Intensive Care Med 2007 33(3):477-84 [abstract] | Review, by S. David McSwain MD, Duke University, Durham NC | | 2007-07-06 | THERAPY | Umpierrez GE, Cuervo R, Karabell A, Latif K, Freire AX, Kitabchi AE Treatment of diabetic ketoacidosis with subcutaneous insulin aspart. Diabetes Care 2004 27(8):1873-8 [abstract] | Review, by Brian Ely MD, Satid Thammasitboon, MD MHPE, West Virginia University, Morgantown WV | | 2007-06-21 | THERAPY | Angstwurm MW, Engelmann L, Zimmermann T, et al. Selenium in Intensive Care (SIC) study: Results of a prospective randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shock Crit Care Med 2007 35:118-126 [abstract] | Review, by Marvin Mata MD, Kathleen Meert MD, Children | | 2007-06-20 | SYSTEMATIC REVIEW | Marik P. Low-dose dopamine: a systematic review. Intensive Care Med 2002 ; 28: 877-883. [abstract] | Review, by Shira J. Gertz MD, Texas Children's Hospital and Baylor College of Medicine, Houston TX | | 2007-06-08 | PROGNOSIS | Samson RA, Nadkarni VM, Meaney PA, Carey SM, Berg MD, Berg RA; American Heart Association National Registry of CPR Investigators. Outcomes of in-hospital ventricular fibrillation in children N Engl J Med 2006 354(22):2328-39 [abstract] | Review, by Downing Lu MD, Children | | 2007-05-19 | THERAPY | Koeman M, van der Ven AJ, Hak E, et al. Oral Decontamination with Chlorhexidine Reduces the Incidence of Ventilator-associated Pneumonia. Am J Respir Crit Care Med. 2006 173(12):1348-5 [abstract] | Review, by Kelby G. Maher DO, Scot T. Bateman MD, University of Massachusetts Medical Center, Worcester, MA | | 2007-05-19 | DIAGNOSIS | Varpula M, Karlsson S, Ruokonen E, Pettila V. Mixed venous oxygen saturation cannot be estimated by central venous oxygen saturation in septic shock. Intensive Care Med 2006 32(9):1336-43 [abstract] | Review, by Reviewed by Gökhan Kalkan MD, University of California San Francisco | | 2007-05-15 | PROGNOSIS | Wintergerst KA, Buckingham B, Gandrud L, et al. Association of hypoglycemia, hyperglycemia, and glucose variability with morbidity and death in the pediatric intensive care unit Pediatrics 2006 118(1):173-9 [abstract] | Review, by Shira Gertz MD, Texas Children | | 2007-05-02 | PROGNOSIS | Meaney PA, Nadkarni VM, Cook EF, et al. for the American Heart Association National Registry of Cardiopulmonary Resuscitation Investigators. Higher Survival Rates Among Younger Patients After Pediatric Intensive Care Unit Cardiac Arrests. Pediatrics 2006 118:2424-2433 [abstract] | Review, by Jennifer Matchey MD, Medical College of Wisconsin, Children | | 2007-04-24 | SYSTEMATIC REVIEW | Simpson F, Doig GS. Parenteral vs. enteral nutrition in the critically ill patient: a meta-analysis of trials using the intention to treat principle Intensive Care Med. 2005 Jan;31(1):12-23 [abstract] | Review, by Autumn M. Richards MD, Kevin M. Creamer MD, Walter Reed Army Medical Center, Washington, D.C. (1) | | 2007-03-09 | PREDICTION TOOL | Chavez A, Cruz RD, Zaritsky A. Spontaneous breathing trial predicts successful extubation in infants and children Pediatric Critical Care Medicine 2006 7(4):324-8 [abstract] [Full-Text] | Review, by Karl Yen MD, Children | | 2007-02-23 | THERAPY | Mancebo J, Fernandez R, Blanch L, et al. A multicenter trial of prolonged prone ventilation in severe acute respiratory distress syndrome. Am J Respir Crit Care Med. 2006 173(11):1233-9. [abstract] | Review, by Moreshwar S. Desai MD, Pediatric Critical Care, Baylor College of Medicine, Houston, TX | | 2006-12-19 | SYSTEMATIC REVIEW | Friedrich JO, Adhikari N, Herridge MS, Beyene J. Meta-analysis: low-dose dopamine increases urine output but does not prevent renal dysfunction or death. Ann Intern Med. 2005 Apr 5;142(7):510-24 [abstract] | Review, by Omer Mansoor MD, West Virginia University, Morgantown, WV | | 2006-12-19 | THERAPY | Cua CL, Thiagarajan RR, Gauvreau K, et al. Early postoperative outcomes in a series of infants with hypoplastic left heart syndrome undergoing stage I palliation operation with either modified Blalock-Taussig shunt or right ventricle to pulmonary artery conduit. Pediatric Critical Care Medicine 2006 7(3):238-44 [abstract] | Review, by Angela Aramburo MD, University of California San Francisco | | 2006-12-16 | SYSTEMATIC REVIEW | Davison C, Ventre KM, Luchetti M, Randolph AG. Efficacy of interventions for bronchiolitis in critically ill infants: A systematic review and meta-analysis. Pediatr Crit Care Med. 2004 Sep;5(5):482-489. [abstract] | Review, by Omer Mansoor MD, West Virginia University, Morgantown, WV | | 2006-11-29 | THERAPY | Inhaled Nitric Oxide Study Group. Inhaled Nitric Oxide and Persistent Pulmonary Hypertension of the Newborn. N Engl J Med 1997 ; 336: 605-610. [abstract] | Review, by Jessica Oldfield, MBChB MRCPCH, Leeds General Infirmary, LEEDS, United Kingdom | | 2006-10-19 | HARM | Marcin JP, Rutan E, Rapetti PM, Brown JP, Rahnamayi R, Pretzlaff RK. Nurse staffing and unplanned extubation in the pediatric intensive care unit. Pediatr Crit Care Med. 2005 May;6(3):254-257. [abstract] | Review, by Corey Philpot MD, Medical College of Wisconsin and Children's Hospital of Wisconsin, Milwaukee, WI | | 2006-10-10 | PREDICTION TOOL | Alberti C, Brun-Buisson C, Chevret S, et al. for the European Sepsis Study Group. Systemic Inflammatory Response and Progression to Severe Sepsis in Critically Ill Infected Patients. Am J Respir Crit Care Med 2005 ;171 461-468 [abstract] | Review, by by Angela Czaja MD, Seattle Children's Hospital and Regional Medical Center, Seattle, WA | | 2006-10-02 | SURROGATE END POINT | Cambonie G, Milesi C, Fournier-Favre S, et al. Clinical Effects of Heliox Administration for Acute Bronchiolitis in Young Infants Chest 2006 ;129 676-682 [abstract] | Review, by Robert Niebler MD, Children | | 2006-10-02 | PREDICTION TOOL | Durward A, Tibby SM, Skellett S, Austin C, Anderson D, Murdoch IA. The strong ion gap predicts mortality in children following cardiopulmonary bypass surgery. Pediatr Crit Care Med. 2005 May;6(3):281-285 [abstract] | Review, by Asumthia S Jeyapalan DO, Texas Children's Hospital, Baylor College of Medicine, Houston, TX | | 2006-10-02 | THERAPY | Schulze-Neick I, Hartenstein P, Li J, et al. Intravenous sildenafil is a potent pulmonary vasodilator in children with congenital heart disease. Circulation. 2003 Sep 9;108 Suppl 1:II167-73. [abstract] | Review, by Jai Udassi MD FAAP, Ikram Haque MD FAAP, Shands Children's Hospital, University of Florida, College of Medicine, Gainesville, FL | | 2006-09-28 | THERAPY | Krueger WA, Lenhart FP, Neeser G et al. Influence of Combined Intravenous and Topical Antibiotic Prophylaxis on the Incidence of Infections, Organ Dysfunctions, and Mortality in Critically Ill Surgical Patients: A Prospective, Stratified, Randomized, Double-Blind, Placebo-controlled Clinica Am J Respir Crit Care Med 2002 ;166 1029-1037 [abstract] | Review, by Luna Sharma MD, West Virginia University | | 2006-09-24 | THERAPY | National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. Pulmonary-Artery versus Central Venous Catheter to Guide Treatment of Acute Lung Injury. N Engl J Med 2006 354:2213-2224 [abstract] | Review, by Pallavi Patwari MD, Children's Memorial Hospital, Chicago, IL | | 2006-09-22 | THERAPY | de La Cal MA, Cerda E, Garcia-Hierro P, van Saene HK, Gomez-Santos D, Negro E, Lorente JA. Survival benefit in critically ill burned patients receiving selective decontamination of the digestive tract: a randomized, placebo-controlled, double-blind trial. Ann Surg. 2005 241(3):424-30 [abstract] | Review, by H Rowlands MD, Birmingham Childrens Hospital, Birmingham UK | | 2006-09-10 | THERAPY | Van den Berghe G, Wilmer A, Hermans G, et al. Intensive insulin therapy in the medical ICU. N Engl J Med 2006 354(5):449-61 [abstract] | Review, by Kourosh Parsapour, MD and James P. Marcin, MD, MPH, UC Davis Childrens Hospital | | 2006-09-10 | SYSTEMATIC REVIEW | Faustino EV, Apkon M. Persistent hyperglycemia in critically ill children. J Pediatr 2005 146(1):30-4 [abstract] | Review, by Michele Kong, MD University of Birmingham at Alabama, AL | | 2006-09-08 | THERAPY | Garland JS, Alex CP, Henrickson KJ, McAuliffe TL, Maki DG. A vancomycin-heparin lock solution for prevention of nosocomial bloodstream infection in critically ill neonates with peripherally inserted central venous catheters: a prospective, randomized trial. Pediatrics 2005 116(2):e198-205 | Review, by Mary G. Gaspers, MD, Baylor College of Medicine, Texas Childrens Hospital | | 2006-05-24 | THERAPY | Bertolini G, Iapichino G, Radrizzani D, et al. Early enteral immunonutrition in patients with severe sepsis: Results of an interim analysis of a randomized multicentre clinical trial. Intensive Care Med 2003 29: 834-840. [abstract] | Review, by J Kane MD, Medical College Wisconsin, Milwaukee, WI | | 2006-05-23 | PROGNOSIS | Herridge MS, Cheung AM, Tansey CM, et al. One-year outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med 2003 Feb 20;348(8):683-93 [abstract] | Review, by G Wolf | | 2006-05-21 | DIAGNOSTIC TEST | Milling TJ Jr, Rose J, Briggs WM, Birkhahn R, Gaeta TJ, Bove JJ, Melniker LA. Randomized, controlled clinical trial of point-of-care limited ultrasonography assistance of central venous cannulation: The Third Sonography Outcomes Assessment Program (SOAP-3) Trial. Crit Care Med 2005 171:348-353 [abstract] | Review, by Matthew Christopherson MB ChB MRCPCH, Leeds General Infirmary, UK | | 2006-05-18 | PROGNOSIS | Cohan P, Wang C, McArthur DL, et al. Acute secondary adrenal insufficiency after traumatic brain injury: A prospective study. Crit Care Med 2005 Oct;33(10):2358-2366 [abstract] | Review, by A Hoogerland | | 2006-05-16 | PREDICTION | Graciano AL, Balko JA, Rahn DS, Ahmad N, Giroir BP. The Pediatric Multiple Organ Dysfunction Score (P-MODS): Development and validation of an objective scale to measure the severity of multiple organ dysfunction in critically ill children. Crit Care Med 2005 Jul;33(7):1484-1491 [abstract] | Review, by K Hebbar, T Petrillo | | 2006-04-27 | THERAPY | Morelli A, Ricci Z, Bellomo R, et al. Prophylactic fenoldopam for renal protection in sepsis: a randomized, double-blind, placebo-controlled pilot trial. Crit Care Med 2005 Nov;33(11):2451-6 [abstract] | Review, by S Wu | | 2006-04-03 | THERAPY | Oppert M, Schindler R, Husung C, et al., Low-dose hydrocortisone improves shock reversal and reduces cytokine levels in early hyperdynamic septic shock Crit Care Med 2005 Nov;33(11):2457-64 [abstract] | Review, by S van Schaik | | 2006-04-02 | PREDICTION TOOL | Trachsel D, McCrindle BW, Nakagawa S, Bohn DJ, Oxygenation Index Predicts Outcome in Children with Acute Hypoxemic Respiratory Failure Am J Respir Crit Care Me 2005 172:206-211 [abstract] | Review, by C Froehlich J Fortenberry | | 2006-03-25 | PREDICTION TOOL | Leclerc F, Leteurtre S, Duhamel A, et al., Cumulative Influence of Organ Dysfunctions and Septic State on Mortality of Critically Ill Children Am J Respir Crit Care Me 2005 171:348-353 [abstract] | Review, by K Typpo | | 2006-03-18 | PREDICTION TOOL | Thiagarajan RR, Bratton SL, Martin LD, et al., Predictors of Successful Extubation in Children Am J Respir Crit Care Me 1999 160:1562-1566 [abstract] | Review, by K Yen | | 2006-03-11 | PREDICTION TOOL | Cohen S, Springer C, Avital A, et al., Amino-Terminal Pro-Brain-Type Natriuretic Peptide: Heart or Lung Disease in Pediatric Respiratory Distress? Pediatrics 2005 115 1347-1350 [abstract] | Review, by R Srinivasan | | 2006-03-08 | THERAPY | Guerin C, Gaillard S, Lemasson S, et al., Effects of Systematic Prone Positioning in Hypoxemic Acute Respiratory Failure: A Randomized Controlled Trial JAMA 2004 292 2379-2387 [abstract] | Review, by AS Jeyapalan | | 2006-02-24 | THERAPY | Raoof S, Chowdhrey N, Raoof S, et al., Effect of Combined Kinetic Therapy and Percussion Therapy on the Resolution of Atelectasis in Critically Ill Patients Chest 1999 115:1658-1666 [abstract] | Review, by O Borisenko | | 2006-01-27 | SYSTEMATIC REVIEW | Shah MR, Hasselblad V, Stevenson LW, Binanay C, O'Connor CM, Sopko G, Califf RM. Impact of the pulmonary artery catheter in critically ill patients: meta-analysis of randomized clinical trials. JAMA 2005 Oct 5;294(13):1664-70 [abstract] | Review, by S Gertz | | 2006-01-26 | SYSTEMATIC REVIEW | Peter JV, Moran JL, Phillips-Hughes J., , A metaanalysis of treatment outcomes of early enteral versus early parenteral nutrition in hospitalized patients. Crit Care Med 2005 Jan;33(1):213-20 [abstract] | Review, by M Desai | | 2006-01-23 | THERAPY | Shankaran S, Laptook AR, Ehrenkranz RA, et al., Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N Engl J Med 2005 Oct 13;353(15):1574-84 [abstract] | Review, by R Mosalli K Al Faleh | | 2006-01-19 | THERAPY | Curley MA, Hibberd PL, Fineman LD, et al., Effect of prone positioning on clinical outcomes in children with acute lung injury: a randomized controlled trial JAMA 2005 Jul 13;294(2):229-37 [abstract] | Review, by M Paden | | 2006-01-19 | THERAPY | Kim IK, Phrampus E, Venkataraman S, et al. , Helium/oxygen-driven albuterol nebulization in the treatment of children with moderate to severe asthma exacerbations: a randomized, controlled trial. Pediatrics 2005 Nov;116(5):1127-33 [abstract] | Review, by N Dean | | 2006-01-10 | PREDICTION TOOL | Conti G, Montini L, Pennisi MA, et al., A prospective, blinded evaluation of indexes proposed to predict weaning from mechanical ventilation Intensive Care Med 2004 May;30(5):830-6 [abstract] | Review, by A Wratney | | 2005-12-27 | THERAPY | Spragg RG, Lewis JF, Walmrath HD, et al., Effect of recombinant surfactant protein C-based surfactant on the acute respiratory distress syndrome N Engl J Med 2004 351:884-892 [abstract] | Review, by F Norozian | | 2005-12-20 | THERAPY | Fioretto JR, De Moraes MA, Bonatto RC, et al., Acute and sustained effects of early administration of inhaled nitric oxide to children with acute respiratory distress syndrome Pediatric Critical Care Medicine 2004 Sep;5(5):469-74 [abstract] | Review, by J Matchey | | 2005-12-12 | PREDICTION TOOL | Peters MJ, Ross-Russell RI, White D , et al, Early severe neutropenia and thrombocytopenia identifies the highest risk cases of severe meningococcal disease Pediatric Critical Care Medicine 2005 2:225-231 [abstract] | Review, by A Gourishankar | | 2005-12-10 | SYSTEMATIC REVIEW | Hind D, Calvert N, McWilliams R, et al., Ultrasonic locating devices for central venous cannulation: meta-analysis Br Med J 2003 327(7411):361 [abstract] | Review, by E Harry | | 2005-11-25 | PREDICTION TOOL | Gomes Cordeiro AM, Fernandes JC, Troster EJ., , Possible risk factors associated with moderate or severe airway injuries in children who underwent endotracheal intubation Crit Care Med 2004 Jul;5(4):364-8 [abstract] | Review, by A Wratney | | 2005-11-23 | THERAPY | David M, Weiler N, Heinrichs W, et al, High-frequency oscillatory ventilation in adult acute respiratory distress syndrome Intensive Care Med 2003 Oct;29(10):1656-65 [abstract] | Review, by J O'Rourke N Mehta | | 2005-11-17 | THERAPY | Wheeler DS, Jacobs BR, Kenreigh CA, et al., Theophylline versus terbutaline in treating critically ill children with status asthmaticus: A prospective, randomized, controlled trial Pediatric Critical Care Medicine 2005 Mar;6(2):142-147 [abstract] | Review, by A Sharangpani J Natale | | 2005-11-17 | PREDICTION TOOL | Carter BG, Butt W., , , A prospective study of outcome predictors after severe brain injury in children Intensive Care Med 2005 Jun;31(6):840-845 [abstract] | Review, by L Thompson | | 2005-11-04 | THERAPY | Lim DS, Kulik TJ, Kim DW, Charpie JR, Crowley DC, Maher KO. Aminophylline for the prevention of apnea during prostaglandin E1 infusion Pediatrics 2003 Jul;112(1 Pt 1):e27-9 [abstract] | Review, by P Alexander | | 2005-11-02 | PREDICTION TOOL | Malerba G, Romana-Girard F, Cravoisy A, et al., Risk factors of relative adrenocortical deficiency in intensive care patients needing mechanical ventilation Intensive Care Med 2005 31:388-392 [abstract] | Review, by AP Davis | | 2005-10-31 | THERAPY | Wang M, Hays T, Balasa V, et al., Low-dose tissue plasminogen activator thrombolysis in children J Pediatr Hematol Oncol 2003 25(5):379-86 [abstract] | Review, by M Rafay | | 2005-10-05 | SYSTEMATIC REVIEW | Quiroz R, Kucher N, Zou KH, et al., Clinical Validity of a Negative Computed Tomography Scan in Patients With Suspected Pulmonary Embolism: A Systematic Review JAMA 2005 Apr 27;293(16):2012-2017 [abstract] | Review, by S Hanson | | 2005-09-16 | PREDICTION TOOL | Morris MC, Wernovsky G, Nadkarni VM, , Survival outcomes after extracorporeal cardiopulmonary resuscitation instituted during active chest compressions following refractory in-hospital pediatric cardiac arrest Pediatric Critical Care Medicine 2005 Sep;5(5):440-446 [abstract] | Review, by M Frazier A Wratney | | 2005-09-05 | DIAGNOSIS | Mentec H, May-Michelangeli L, Rabbat A, et al., Blind and bronchoscopic sampling methods in suspected ventilator-associated pneumonia: A multicentre prospective study Intensive Care Med 2004 30-1319-1326. [abstract] | Review, by M Weber | | 2005-08-24 | PREDICTION TOOL | Pizarro CF, Troster EJ, Damiani D, Carcillo JA., Absolute and relative adrenal insufficiency in children with septic shock. Crit Care Med 2005 Apr;33(4):855-859 [abstract] | Review, by A Hsu MJ Bell | | 2005-07-30 | THERAPY | Willson DF, Thomas NJ, Markovitz BP,, et al. , Effect of Exogenous Surfactant (Calfactant) in Pediatric Acute Lung Injury: A Randomized Controlled Trial JAMA 2005 293 470-476 [abstract] | Review, by A Shieh Czaja | | 2005-07-11 | PREDICTION TOOL | Graf WD, Cummings P, Quan L, Brutocao D. , Predicting outcome in pediatric submersion victims Ann Emerg Med 1995 Sep;26(3):312-9 [abstract] | Review, by A Godshall | | 2005-07-05 | THERAPY | Park M, Sangean MC, de S Volpe M, et al., Randomized, prospective trial of oxygen, continuous positive airway pressure, and bilevel positive airway pressure by face mask in acute cardiogenic pulmonary edema. Crit Care Med 2004 Dec;32(12):2407-15 [abstract] | Review, by J Kane MD, Medical College Wisconsin, Milwaukee, WI | | 2005-06-18 | PREDICTION TOOL | Kurachek SC, Newth CJ, Quasney MW, et al., Extubation failure in pediatric intensive care: A multiple-center study of risk factors and outcomes Crit Care Med 2003 Nov;31(11):2657-64 [abstract] | Review, by S Primis A Wratney | | 2005-05-24 | OUTCOMES | Rossi AF, Khan DM, Hannan R, et al, Goal-directed medical therapy and point-of-care testing improve outcomes after congenital heart surgery Intensive Care Med 2005 Jan;31(1):98-104 [abstract] | Review, by M Drayer R Harrison | | 2005-05-19 | PROGNOSIS | Horisberger T, Fischer JE, Fanconi S. One-year survival and neurological outcome after pediatric cardiopulmonary resuscitation Intensive Care Med 2002 28: 365-368. [abstract] | Review, by P Prodhan, N Noviski | | 2005-05-06 | THERAPY | Hoffman GM, Tweddell JS, Ghanayem NS, et al., Alteration of the critical arteriovenous oxygen saturation relationship by sustained afterload reduction after the Norwood procedure J Thorac Cardiovasc Surg 2004 Mar;127(3):738-45 [abstract] | Review, by N Lin | | 2005-05-03 | HARM | Landrigan CP, Rothschild JM, Cronin JW, et al., Effect of reducing interns' work hours on serious medical errors in intensive care units N Engl J Med 2004 Oct 28;351(18):1838-48 [abstract] | Review, by L Huang J Lajoie | | 2005-04-28 | THERAPY | NHLBI ARDS Clinical Trials Network, , , , Higher versus Lower Positive End-Expiratory Pressures in Patients with the Acute Respiratory Distress Syndrome N Engl J Med 2004 351:327-336 [abstract] | Review, by M White | | 2005-04-13 | SYS-REVIEW | Keenan SP, Sinuff T, Cook DJ, Hill NS. Does noninvasive positive pressure ventilation improve outcome in acute hypoxemic respiratory failure? A systematic review. Crit Care Med 2004 Dec;32(12):2516-23 [abstract] | Review, by K Yen | | 2005-04-07 | PREDICTION TOOL | Clancy RR, McGaurn SA, Wernovsky G, et al., Risk of seizures in survivors of newborn heart surgery using deep hypothermic circulatory arrest Pediatrics 2003 111(3):592-601 [abstract] | Review, by G Deshpande A Torres | | 2005-03-19 | DIAGNOSTIC TECH | Levy RL, Chiavacci RM, Nicolson SC , et al. , An Evaluation of a Noninvasive Cardiac Output Measurement Using Partial Carbon Dioxide Rebreathing in Children Anesth Analg 2004 99 1642-1647 [abstract] | Review, by M Weber | | 2005-03-13 | SYSTEMATIC REVIEW | McIntyre LA, Fergusson DA, Hebert PC, et al., Prolonged Therapeutic Hypothermia After Traumatic Brain Injury in Adults: A Systematic Review JAMA 2003 289 2992-2999 [abstract] | Review, by N Shafi M Mariscalco | | 2005-03-13 | SYSTEMATIC REVIEW | Henderson WR, Dhingra VK, Chittock DR, et al., Hypothermia in the management of traumatic brain injury. A systematic review and meta-analysis. Br Med J 2003 Oct;29(10):1637-44 [abstract] | Review, by N Shafi M Mariscalco | | 2005-03-08 | THERAPY | Meert KL, Daphtary KM, Metheny NA, , Gastric vs Small-Bowel Feeding in Critically Ill Children Receiving Mechanical Ventilation: A Randomized Controlled Trial Chest 2004 126 872-878 [abstract] | Review, by S Rishmawi | | 2005-03-06 | PREDICTION | Charpie JR, Dekeon MK, Goldberg CS, Mosca RS, Bove EL, Kulik TJ. Serial blood lactate measurements predict early outcome after neonatal repair or palliation for complex congenital heart disease. J Thorac Cardiovasc Surg. 2000 Jul;120(1):73-80 [abstract] | Review, by A Gazit | | 2005-03-03 | META-ANALYSIS | Annane D, Bellissant E, Bollaert PE, et al., Corticosteroids for severe sepsis and septic shock: a systematic review and meta-analysis Br Med J 2004 329(7464):480 [abstract] | Review, by M Desai | | 2005-03-02 | PREDICTION TOOL | Bechtel K, Stoessel K, Leventhal JM , et al., Characteristics That Distinguish Accidental From Abusive Injury in Hospitalized Young Children With Head Trauma Pediatrics 2004 114 165-168 [abstract] | Review, by M Winkler | | 2005-03-01 | PREDICTION TOOL | Srinivasan V, Spinella PC, Drott HR, et al., Association of timing, duration, and intensity of hyperglycemia with intensive care unit mortality in critically ill children. Pediatric Critical Care Medicine 2004 Jul;5(4):329-36 [abstract] | Review, by A Bass | | 2005-02-28 | THERAPY/PREVENTION | Galban C, Montejo JC, Mesejo A, et al., An immune-enhancing enteral diet reduces mortality rate and episodes of bacteremia in septic intensive care unit patients Crit Care Med 2000 28(3):643-8 [abstract] | Review, by R Rastmanesh | | 2005-02-27 | THERAPY/PREVENTION | Taylor RW, Zimmerman JL, Dellinger RP, et al., Low-dose inhaled nitric oxide in patients with acute lung injury: a randomized controlled trial JAMA 2004 Apr 7;291(13):1603-9 [abstract] | Review, by R Orellana | | 2005-02-20 | PROGNOSIS | Hamrick SE, Gremmels DB, Keet CA, et al., Neurodevelopmental outcome of infants supported with extracorporeal membrane oxygenation after cardiac surgery Pediatrics 2003 Jun;111(6 Pt 1):e671-5 [Full-Text] | Review, by S Cooper | | 2005-02-14 | THERAPY/PREVENTION | Leon C, Ruiz-Santana S, Rello J, et al., Benefits of minocycline and rifampin-impregnated central venous catheters: A prospective, randomized, double-blind, controlled, multicenter trial Intensive Care Med 2004 30:1891-1899 [abstract] | Review, by A Jeyapalan | | 2005-01-25 | PREDICTION TOOL | Farias JA, Alía I, Retta A, et al., An evaluation of extubation failure predictors in mechanically ventilated infants and children Intensive Care Med 2002 28:752-757 [abstract] | Review, by A Wratney DK Benjamin | | 2005-01-21 | THERAPY | Meert KL, Daphtary KM, Metheny NA, , Gastric vs Small-Bowel Feeding in Critically Ill Children Receiving Mechanical Ventilation: A Randomized Controlled Trial Chest 2004 126 872-878 [abstract] | Review, by D Hsing A Madikians | | 2005-01-18 | PROGNOSIS | Foland JA, Fortenberry JD, Warshaw BL, et al., Fluid overload before continuous hemofiltration and survival in critically ill children: a retrospective analysis Crit Care Med 2004 Aug;32(8):1771-6 [abstract] | Review, by L Thompson | | 2005-01-13 | PROGNOSIS | Palchak MJ, Holmes JF, Vance CW, et al., Does an isolated history of loss of consciousness or amnesia predict brain injuries in children after blunt head trauma? Pediatrics 2004 Jun;113(6):e507-13 [abstract] | Review, by K Typpo | | 2005-01-10 | THERAPY | Esteban A, Frutos-Vivar F, Ferguson ND, et al., Noninvasive Positive-Pressure Ventilation for Respiratory Failure after Extubation N Engl J Med 2004 350:2452-2460 [abstract] | Review, by T Cholis | | 2004-12-22 | THERAPY/PREVENTION | Slota M, Green M, Farley A, Janosky J, Carcillo J The role of gown and glove isolation and strict handwashing in the reduction of nosocomial infection in children with solid organ transplantation Crit Care Med 2001 29(2):405-412 [abstract] | Review, by A Lin | | 2004-12-16 | THERAPY | Dahlem P, van Aalderen WMC, de Neef M, Dijkgraaf MGW, Bos AP Randomized controlled trial of aerosolized prostacyclin therapy in children with acute lung injury Crit Care Med 2004 32:1055-1060 [abstract] | Review, by AA Arikan | | 2004-12-07 | PROGNOSIS | Bandla HPR, Hopkins RL, Beckerman RC, Gozal D, Pulmonary Risk Factors Compromising Postoperative Recovery After Surgical Repair for Congenital Heart Disease Chest 1999 116:740-747 [abstract] | Review, by J Geracht J Barron | | 2004-12-06 | THERAPY | Gupta AA, Leaker M, Andrew M, et al. , Safety and outcomes of thrombolysis with tissue plasminogen activator for treatment of intravascular thrombosis in children J Pediatr 2001 139(5):682-8 [abstract] | Review, by J Berger | | 2004-11-30 | ECONOMIC ANALYSIS | Angus DC, Linde-Zwirble WT, PROWESS Investigators, , Cost-effectiveness of drotrecogin alfa (activated) in the treatment of severe sepsis Crit Care Med 2003 Jan;31(1):1-11 [abstract] | Review, by N Mehta | | 2004-10-28 | THERAPY | Chastre J, Wolff M, Fagon J-Y, et al., Comparison of 8 vs 15 Days of Antibiotic Therapy for Ventilator-Associated Pneumonia in Adults: A Randomized Trial JAMA 2003 290 2588-2598 [abstract] | Review, by J Cortes | | 2004-10-27 | THERAPY | Wenzel V, Krismer AC, Arntz HR, et al., A Comparison of Vasopressin and Epinephrine for Out-of-Hospital Cardiopulmonary Resuscitation N Engl J Med 2003 350:105-113 [abstract] | Review, by K Denev | | 2004-10-23 | THERAPY | Thill PJ, McGuire JK, Baden HP, et al., Noninvasive positive-pressure ventilation in children with lower airway obstruction Pediatric Critical Care Medicine 2004 Jul;5(4):337-342 [abstract] | Review, by S Rishmawi | | 2004-10-14 | THERAPY | Nava S, Carbone G, DiBattista N, et al., Noninvasive ventilation in cardiogenic pulmonary edema: a multicenter randomized trial Am J Respir Crit Care Me 2003 Dec 15;168(12):1432-7 [abstract] | Review, by L Thompson | | 2004-09-27 | THERAPY | Krishnan JA, Moore D, Robeson C, et al., A Prospective, Controlled Trial of a Protocol-based Strategy to Discontinue Mechanical Ventilation Am J Respir Crit Care Me 2004 169 673-678 [abstract] | Review, by A Lee M Nilufer | | 2004-09-08 | THERAPY | Trachtman H, Cnaan A, Christen E, et al., Effect of an oral Shiga toxin-binding agent on diarrhea-associated hemolytic uremic syndrome in children: a randomized controlled trial JAMA 2003 290(10):1337-44 [abstract] | Review, by A Daneshmand R Sanders | | 2004-09-05 | QUALITY OF LIFE | Culbert EL, Ashburn DA, Cullen-Dean G, et al., Quality of Life of Children After Repair of Transposition of the Great Arteries Circulation 2003 108 857-862 [abstract] | Review, by D Stockwell J Natale | | 2004-09-02 | THERAPY | Warren BL, Eid A, Singer P, et al., High-Dose Antithrombin III in Severe Sepsis: A Randomized Controlled Trial JAMA 2001 286:1869-1878 [abstract] | Review, by K Hebbar T Petrillo | | 2004-08-26 | THERAPY | Soroksky A, Stav D, Shpirer I, , A Pilot Prospective, Randomized, Placebo-Controlled Trial of Bilevel Positive Airway Pressure in Acute Asthmatic Attack Chest 2003 123 1018-1025 [abstract] | Review, by K Lewis | | 2004-08-25 | PREDICTION TOOL | Durward A, Mayer A, Skellett S, et al., Hypoalbuminaemia in critically ill children: incidence, prognosis, and influence on the anion gap Arch Dis Child 2003 May;88(5):419-22 [abstract] | Review, by R Lambert | | 2004-08-24 | PREDICTION TOOL | Castellanos-Ortega I, Delgado-Rodriguez M, Llorca J, et al., A new prognostic scoring system for meningococcal septic shock in children. Comparison with three other scoring systems. Intensive Care Med 2002 28: 341-351 [abstract] | Review, by A Vohra | | 2004-08-15 | THERAPY | SAFE Study Investigators, , , , A comparison of albumin and saline for fluid resuscitation in the Intensive Care Unit N Engl J Med 2004 350:2247-2256 [abstract] | Review, by S van Schaik | | 2004-08-11 | THERAPY | Cooper DJ, Myles PS, McDermott FT, et al. Prehospital hypertonic saline resuscitation of patients with hypotension and severe traumatic brain injury: a randomized controlled trial JAMA 2004 Mar 17;291(11):1350-7 [abstract] | Review, by G Mander | | 2004-08-06 | PROGNOSIS | Banwell BL, Mildner RJ, Hassall AC, et al., Muscle weakness in critically ill children Neurology 2003 Dec 23;61(12):1779-82 [abstract] | Review, by J Alten M Mariscalco | | 2004-08-02 | PREDICTION TOOL | De Bast Y, De Backer D, Moraine JJ, et al., The cuff leak test to predict failure of tracheal extubation for laryngeal edema Intensive Care Med 2002 28: 1267-1272 [abstract] | Review, by A Wratney DK Benjamin Jr | | 2004-07-16 | THERAPY | Perondi MBM, Reis AG, Paiva EF, Nadkarni VM, Berg RA A Comparison of High-Dose and Standard-Dose Epinephrine in Children with Cardiac Arrest N Engl J Med 2004 350:1722-1730 [abstract] | Review, by M Sharma | | 2004-07-06 | DIAGNOSIS | Barret JP, Ramzy PI, Wolf SE, Herndon DN, Sensitivity and Specificity of Bronchoalveolar Lavage and Protected Bronchial Brush in the Diagnosis of Pneumonia in Pediatric Burn Patients Arch Surg 1999 134:1243-1247 [abstract] | Review, by A Vohra | | 2004-06-19 | PROGNOSIS | Goh AYT,, Abdel-Latif MEA, Lum LCS, Abu-Bakar MN, Outcome of children with different accessibility to tertiary pediatric intensive care in a developing country - a prospective cohort study Intensive Care Med 2003 29: 97-102 [abstract] | Review, by J Cortes | | 2004-06-04 | THERAPY | Wainwright C, Altamarino L, Medico-Cirujano , et al., A Multicenter, Randomized, Double-Blind, Controlled Trial of Nebulized Epinephrine in Infants with Acute Bronchiolitis. N Engl J Med 2003 349:27-35 [abstract] | Review, by P Prodhan N Noviski | | 2004-06-01 | PREDICTION TOOL | Bernal W, Donaldson N, Wyncoll D, Wendon J, Blood lactate as an early predictor of outcome in paracetamol-induced acute liver failure: a cohort study Lancet 2002 Feb 16;359(9306):558-63 [abstract] | Review, by P Prodhan N Noviski | | 2004-05-21 | THERAPY | The Hypothermia After Cardiac Arrest Study Group. Mild Therapeutic Hypothermia to Improve the Neurologic Outcome After Cardiac Arrest N Engl J Med 2002 346:549-56 [abstract] | Review, by S Cooper | | 2004-04-29 | PREDICTION TOOL | Brown KL, Ridout DA, Goldman AP, et al., Risk factors for long intensive care unit stay after cardiopulmonary bypass in children Crit Care Med 2003 31(1):28-33 [abstract] | Review, by A Torres | | 2004-04-29 | PREDICTION TOOL | Hatherill M, Waggie Z, Purves L, et al, Mortality and the nature of metabolic acidosis in children with shock Intensive Care Med 2003 Feb;29(2):286-91 [abstract] | Review, by R Lambert A Zaritsky | | 2004-03-30 | ECONOMIC ANALYSIS | Manns BJ, Lee H, Doig CJ, et al., An economic evaluation of activated protein C treatment for severe sepsis N Engl J Med 2002 347:993-1000 [abstract] | Review, by A Arikan | | 2004-03-19 | PREDICTION TOOL | Perez A, Minces PG, Schnitzler EJ, et al., Jugular venous oxygen saturation or arteriovenous difference of lactate content and outcome in children with severe traumatic brain injury Pediatric Critical Care Medicine 2003 Jan;4(1):33-8 [abstract] | Review, by J Alten M Mariscalco | | 2004-03-05 | THERAPY | Richard C, Warszawski J, Angurl N, et al., Early Use of the Pulmonary Artery Catheter and Outcomes in Patients With Shock and Acute Respiratory Distress Syndrome: A Randomized Controlled Trial JAMA 2003 290 2713-2720 [abstract] | Review, by S. Thammasitboon S. Cortes | | 2004-02-14 | THERAPY | Ferrer M, Esquinas A, Leon M, Gonzalez G, Alarcon A, Torres A. Noninvasive ventilation in severe hypoxemic respiratory failure: a randomized clinical trial Am J Respir Crit Care Med. 2003 Dec 15;168(12):1438-44 [abstract] | Review, by H Sahhar | | 2004-02-04 | PROGNOSIS | Jacobe SJ, Hassan A, Veys P, Mok Q, Outcome of children requiring admission to an intensive care unit after bone marrow transplantation. Crit Care Med 2003 31(5):1299-305 [abstract] | Review, by E Harry | | 2004-02-02 | OUTCOMES | Han YY, Carcillo JA, Dragotta MA, et al., Early Reversal of Pediatric-Neonatal Septic Shock by Community Physicians Is Associated With Improved Outcome Pediatrics 2003 112 793-799 [abstract] | Review, by N Faqih | | 2004-02-02 | THERAPY/PREVENTION | Smulders K, van der Hoeven H, Weers-Pothoff I, Vandenbroucke-Grauls C, A Randomized Clinical Trial of Intermittent Subglottic Secretion Drainage in Patients Receiving Mechanical Ventilation Chest 2002 121: 858-862 [abstract] | Review, by M Sehgal | | 2004-01-06 | PREDICTION TOOL | Finney SJ, Zekveld C, Elia A, Evans TW, Glucose control and mortality in critically ill patients JAMA 2003 290(15):2041-7 [abstract] | Review, by A Chavez | | 2003-12-31 | THERAPY | Pettignano R, Fortenberry JD, Heard ML, et al., Primary use of the venovenous approach for extracorporeal membrane oxygenation in pediatric acute respiratory failure Pediatric Critical Care Medicine 2003 4(3):291-8 [abstract] | Review, by M Sharma | | 2003-12-27 | PREDICTION TOOL | Rossi AF, Seiden HS, Gross RP, Griepp RB, Oxygen transport in critically ill infants after congenital heart operations Ann Thorac Surg 1999 67(3):739-44 [abstract] [Full-Text] | Review, by A Shahin | | 2003-12-15 | THERAPY | Jacobs S, Price Evans DA, Tariq M, et al., Fluconazole improves survival in septic shock: A randomized double-blind prospective study Crit Care Med 2003 Jul;31(7):1938-46 [abstract] | Review, by P Meaney | | 2003-12-15 | THERAPY | DiCarlo JV, Alexander SR, Agarwal R, Schiffman JD, Continuous veno-venous hemofiltration may improve survival from acute respiratory distress syndrome after bone marrow transplantation or chemotherapy J Pediatr Hematol Oncol 2003 Oct;25(10):801-5 [abstract] | Review, by E Cullen | | 2003-12-04 | DIAGNOSIS | Sirvent JM, Vidaur L, Gonzalez S, et al., Microscopic examination of intracellular organisms in protected bronchoalveolar mini-lavage fluid for the diagnosis of ventilator-associated pneumonia Chest 2003 123(2):518-23 [abstract] | Review, by C Kennedy | | 2003-11-24 | THERAPY | Patel H, Platt RW, Pekeles GS, Ducharme FM, A randomized, controlled trial of the effectiveness of nebulized therapy with epinephrine compared with albuterol and saline in infants hospitalized for acute viral bronchiolitis J Pediatr 2002 141(6):818-24 [abstract] | Review, by R Lambert R Sanders | | 2003-11-14 | DIAGNOSIS | Marik PE, Zaloga GP, , , Adrenal insufficiency during septic shock Crit Care Med 2003 31(1):141-5 [abstract] | Review, by P Prabhakaran | | 2003-11-04 | THERAPY | Ferrer M, Esquinas A, Arancibia F, et al., Non-invasive ventilation during persistent weaning failure. A randomized controlled trial Am J Respir Crit Care Me 2003 168(1):70-6 [abstract] | Review, by L Smith | | 2003-10-13 | SYSTEMATIC REVIEW | Heyland DK, Novak F, Drover JW , et al., Should Immunonutrition Become Routine in Critically Ill Patients? A Systematic Review of the Evidence JAMA 2001 286:944-953 [abstract] | Review, by N Mehta | | 2003-10-06 | PROGNOSIS | De Jonghe B, Sharshar T, Lefaucheur JP, et al., Paresis acquired in the intensive care unit: a prospective multicenter study JAMA 2002 288(22):2859-67 [abstract] | Review, by J Alten | | 2003-09-26 | THERAPY | Moller JC, Schaible T, Roll C, et al., Treatment with bovine surfactant in severe acute respiratory distress syndrome in children: a randomized multicenter study Intensive Care Med 2003 29(3):437-46 [abstract] | Review, by N Mehta | | 2003-09-24 | SYSTEMATIC REVIEW | Sokol J, Jacobs SE, Bohn D, , Inhaled nitric oxide for acute hypoxemic respiratory failure in children and adults Cochrane Review 2002 Issue 4 2002. Oxford: Update Software [abstract] | Review, by S Thammasitboon S Thammasitboon | | 2003-09-15 | PREDICTION TOOL | Robertson CMT, Joffe AR, Moore AJ, Watt JM, Neurodevelopmental outcome of young pediatric intensive care survivors of serious brain injury Pediatric Critical Care Medicine 2002 3(4):345-350 [abstract] | Review, by R Graham | | 2003-08-29 | THERAPY | Hoffman TM, Wernovsky G, Atz AM, et al., Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease Circulation 2003 Feb 25;107(7):996-1002 [abstract] | Review, by A Torres | | 2003-07-25 | SYSTEMATIC REVIEW | Ho AMH, Lee A, Karmakar MK , et al., Heliox vs Air-Oxygen Mixtures for the Treatment of Patients With Acute Asthma: A Systematic Overview Chest 2003 123 882-890 [abstract] | Review, by G Wolf | | 2003-07-07 | PROGNOSIS | Marcin JP, Glaser N, Barnett P, et al., Factors associated with adverse outcomes in children with diabetic ketoacidosis-related cerebral edema J Pediatr 2002 141(6):793-7 [abstract] | Review, by C Kennedy | | 2003-07-06 | PROGNOSIS | Lamas A, Otheo E, Ros P, et al., Prognosis of child recipients of hematopoietic stem cell transplantation requiring intensive care Intensive Care Med 2003 29: 91-96 [abstract] | Review, by L Hite | | 2003-06-24 | THERAPY | Martin GS, Mangialardi RJ, Wheeler AP, et al, Albumin and furosemide therapy in hypoproteinemic patients with acute lung injury Crit Care Med 2002 30(10):2175-82 [abstract] | Review, by D Godorov | | 2003-06-21 | THERAPY | Weaver LK, Hopkins RO, Chan KJ , et al., Hyperbaric oxygen for acute carbon monoxide poisoning N Engl J Med 2002 347:1057-67 [abstract] | Review, by M Fiore | | 2003-06-16 | THERAPY | Olschewski H, Simmoneau G, Galie N, et al., Inhaled Iloprost for Severe Pulmonary Hypertension N Engl J Med 2002 347(5):322-9 [abstract] | Review, by A Arikan | | 2003-06-12 | THERAPY | Inhaled Nitric Oxide and Hypoxic Respiratory Failure in Infants With Congenital Diaphragmatic Hernia Pediatrics 1997 99: 838-845 [abstract] | Review, by The Neonatal Inhaled Nitric Oxide Study Group (NINOS) | | 2003-05-22 | PREDICTION TOOL | Bersten AD, Hunt T, Nicholas TE, et al., Elevated Plasma Surfactant Protein-B Predicts Development of Acute Respiratory Distress Syndrome in Patients with Acute Respiratory Failure Am J Respir Crit Care Me 2001 164 648-652 [abstract] | Review, by S Huntoon Vitali | | 2003-05-17 | ICU OUTCOMES | Bulger EM, Nathens AB, Rivara FP, et al., Management of severe head injury: institutional variations in care and effect on outcome Crit Care Med 2002 30(8):1870-6 [abstract] | Review, by J Adler | | 2003-05-07 | THERAPY | Arons MM, Wheller AP, Bernard GR, et al., Effects of ibuprofen on the physiology and survival of hypothermic sepsis Crit Care Med 1999 27:699-707 [abstract] | Review, by W Arias | | 2003-05-04 | SYSTEMATIC REVIEW | Kern JW, Shoemaker WC, , , Meta-analysis of hemodynamic optimization in high-risk patients Crit Care Med 2002 30(8):1686-92 [abstract] | Review, by S Thammasitboon S Thammasitboon | | 2003-04-25 | THERAPY | Randolph AG, Wypij D, Venkataraman ST, et al., for PALISI network Effect of Mechanical Ventilator Weaning Protocols on Respiratory Outcomes in Infants and Children: A Randomized Controlled Trial JAMA 2002 288:2561-2568 [abstract] | Review, by M Twite | | 2003-04-21 | THERAPY | Herndon DN, Hart DW, Wolf SE, et al., Reversal of catabolism by beta-blockade after severe burns N Engl J Med 2001 345: 1223-1229 [abstract] | Review, by M Sharma K Meert | | 2003-04-14 | THERAPY | Miura E, Procianoy RS, Bittar C , et al., A Randomized, Double-Masked, Placebo-Controlled Trial of Recombinant Granulocyte Colony-Stimulating Factor Administration to Preterm Infants With the Clinical Diagnosis of Early-Onset Sepsis Pediatrics 2001 107:30-35 [abstract] | Review, by W Arias | | 2003-04-04 | PREDICTION TOOL | Limperopoulos C, Majnemer A, Shevell MI, et al., Predictors of developmental disabilities after open heart surgery in young children with congenital heart defects J Pediatr 2002 141(1):51-8 [abstract] | Review, by L Elbahlawan | | 2003-04-02 | HARM | Schmugge M, Risch L, Huber A, Fischer JE, Heparin-Induced Thrombocytopenia-Associated Thrombosis in Pediatric Intensive Care Patients Pediatrics 2002 109:e10 [abstract] | Review, by K Mistry | | 2003-03-24 | THERAPY | Lopriore , Markhorst D, Gemke RJBJ, , Ventilator-associated pneumonia and upper airway colonisation with Gram negative bacilli: the role of stress ulcer prophylaxis in children Intensive Care Med 2002 28: 763-767 [abstract] | Review, by D Godorov | | 2003-03-14 | SYSTEMATIC REVIEW | Markovitz BP, Randolph AG, , , Corticosteroids for the Prevention of Reintubation and Postextubation Stridor in Pediatric Patients: A Meta-Analysis Pediatric Critical Care Medicine 2002 3:223-226 [abstract] [Full-Text] | Review, by K Brinkman | | 2003-03-10 | THERAPY/PREVENTION | Corwin HL, Gettinger A, Pearl RG, et al. , Efficacy of recombinant human erythropoietin in critically ill patients: a randomized controlled trial JAMA 2002 288(22):2827-35 [abstract] | Review, by M Cooper | | 2003-03-10 | THERAPY | Polderman KH, Joe RTT, Peerdeman SM , et al., Effects of therapeutic hypothermia on intracranial pressure and outcome in patients with severe head injury Intensive Care Med 2002 28: 1563-1573 [abstract] | Review, by S Thammasitboon S Thammasitboon | | 2003-03-09 | THERAPY/PREVENTION | Qureshi F, Zaritsky A, Poirier MP, , Comparative efficacy of oral dexamethasone versus oral prednisone in acute pediatric asthma J Pediatr 2001 139(1):20-6 [abstract] | Review, by A Torres | | 2003-03-02 | THERAPY | Bettendorf M, Schmidt KG, Grulich-Henn J, et al., Tri-iodothyronine treatment in children after cardiac surgery: a double-blind, randomised, placebo-controlled study Lancet 2000 356(9229):529-34 [abstract] | Review, by L Rajagopalan | | 2003-02-08 | HARM | Taylor RW, Manganaro L, O'Brien J, Trottier SJ, Parkar N, Veremakis C. Impact of allogenic packed red blood cell transfusion on nosocomial infection rates in the critically ill patient Crit Care Med 2002 30(10):2249-54 [abstract] | Review, by R Orellana | | 2003-01-20 | THERAPY | Esteban A, Alia I, Gordo F, et al. , Prospective Randomized Trial Comparing Pressure-Controlled Ventilation and Volume-Controlled Ventilation in ARDS Chest 2000 117(6):1690-1696 [abstract] [Full-Text] | Review, by A Pelaez | | 2003-01-17 | THERAPY/PREVENTION | Ntoumenopoulos G, Presneill JJ, McElholum M, Cade JF, Chest physiotherapy for the prevention of ventilator-associated pneumonia Intensive Care Med 2002 28: 850-856 [abstract] | Review, by N Hoover J Stockwell | | 2003-01-07 | THERAPY | Derdak S, Mehta S, Stewart TE, et al., High-Frequency Oscillatory Ventilation for Acute Respiratory Distress Syndrome in Adults Am J Respir Crit Care Me 2002 166:801-808 [abstract] | Review, by K Ventre | | 2002-12-26 | THERAPY | Busund R, Koukline V, Utrobin U, et al., Plasmapheresis in severe sepsis and septic shock: a prospective, randomised, controlled trial Intensive Care Med 2002 28: 1434-1439 [abstract] | Review, by J Krishnan V Vaiyda | | 2002-12-04 | SYSTEMATIC REVIEW | Marin MG, Lee JC, Skurnick JH, , Prevention of nosocomial bloodstream infections: effectiveness of antimicrobial-impregnated and heparin-bonded central venous catheters Crit Care Med 2000 Sep;28(9):3332-8 [abstract] | Review, by K Mistry | | 2002-11-24 | PREDICTION | Hackbarth RM, Rzeszutko KM, Sturm G, et al. Survival and functional outcome in pediatric traumatic brain injury: a retrospective review and analysis of predictive factors Crit Care Med 2002 30(7):1630-5 [abstract] | Review, by J Krishnan, W Morrison | | 2002-11-06 | THERAPY/PREVENTION | Annane D, Sebille V, Charpentier C, et al., Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock JAMA 2002 288(7):862-71 [abstract] [Full-Text] | Review, by P Kamat J Fortenberry | | 2002-11-03 | PREDICTION TOOL | Nuckton TJ, Alonso JA, Kallet RH, et a;/, Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome N Engl J Med 2002 346(17):1281-6 [abstract] | Review, by S Kannan K Meert | | 2002-11-01 | ECONOMIC ANALYSIS | Rainer TH, Jacobs P, Ng YC , et al, Cost effectiveness analysis of intravenous ketorolac and morphine for treating pain after limb injury: double blind randomised controlled trial Br Med J 2000 321:1247-1252 [abstract] [Full-Text] | Review, by A Torres | | 2002-10-20 | PREDICTION | Khamiees M, Raju P, DeGirolamo A, Amoateng-Adjepong Y, Manthous CA. Predictors of Extubation Outcome in Patients Who Have Successfully Completed a Spontaneous Breathing Trial Chest 2001 120 1262-1270 [abstract] | Review, by J Barron | | 2002-10-01 | THERAPY | Luchetti M, Ferrero F, Gallini C, et al., Multicenter randomized, controlled study of porcine surfactant in severe respiratory syncytial virus-induced respiratory failure Pediatric Critical Care Medicine 2002 3:261-268 [abstract] [Full-Text] | Review, by M Wilhelm | | 2002-09-24 | THERAPY | Martinon-Torres F, Rodriguez-Nunez A, Martinon-Sanchez JM, , Heliox Therapy in Infants With Acute Bronchiolitis Pediatrics 2002 109:68-73 [abstract] [Full-Text] | Review, by H Trivedi K Biagas | | 2002-09-20 | PREDICTION TOOL | Uusaro A, Chittock DR, Russell JA, , Stress test and gastric-arterial PCO2 measurement improve prediction of successful extubation Crit Care Med 2000 28(7):2313-9 [abstract] | Review, by N Hoover A Vats | | 2002-09-06 | THERAPY | Smyrnios NA, Connolly A, Wilson MM, , Effects of a multifaceted, multidisciplinary, hospital-wide quality improvement program on weaning from mechanical ventilation Crit Care Med 2002 30(6):1224-30 [abstract] | Review, by S Thammasitboon S Thammasitboon | | 2002-09-05 | PROGNOSIS | Mangialardi RJ, Martin GS, Bernard GR, et al., Hypoproteinemia predicts acute respiratory distress syndrome development, weight gain, and death in patients with sepsis Crit Care Med 2000 28(9):3137-45 [abstract] | Review, by N Faqih | | 2002-08-26 | PREDICTION TOOL | Wells RG, Vetter C, Laud P, , Intracranial hemorrhage in children younger than 3 years: prediction of intent Arch Pediatr Adolesc Med 2002 156(3):252-7 [abstract] | Review, by G Capraro S Bateman | | 2002-08-21 | SYSTEMATIC REVIEW | Wilkes MM, Navick RJ, , , Patient Survival after Human Albumin Administration A Meta-Analysis of Randomized, Controlled Trials Ann Intern Med 2001 135:149-164 [abstract] | Review, by A Torres | | 2002-08-19 | PREDICTION | Viccellio P, Simon H, Pressman BD, et al. A Prospective Multicenter Study of Cervical Spine Injury in Children Pediatrics 2001 2001;108 e20 [abstract] [Full-Text] | Review, by K Moynihan Hardart | | 2002-08-13 | HARM | Van Houten MA, Uiterwaal CS, Heesen GJ, et al., Does the empiric use of vancomycin in pediatrics increase the risk for Gram-negative bacteremia? Pediatr Infect Dis J 2001 20(2):171-7 [abstract] | Review, by C Kennedy | | 2002-07-26 | ICU OUTCOMES | Nathens AB, Jurkovich GJ, Maier RV , et al., Relationship between trauma center volume and outcomes JAMA 2001 285(9):1164-71 [abstract] [Full-Text] | Review, by K Hardart | | 2002-07-22 | THERAPY | Farias JA, Retta A, et al., , A comparison of two methods to perform a breathing trial before extubation in pediatric intensive care patients Intensive Care Med 2001 27:1649-1654 [abstract] | Review, by A Arikan M McPherson | | 2002-07-15 | THERAPY/PREVENTION | Bergmans DCJJ, Bonten MJM, Gaillard CA, et al., Prevention of Ventilator-associated Pneumonia by Oral Decontamination A Prospective, Randomized, Double-blind, Placebo-controlled Study Am J Respir Crit Care Me 2001 164:382-388 [abstract] | Review, by P Kamat J Stockwell | | 2002-07-13 | THERAPY/PREVENTION | Clancy RR, MCGaurn SA, Goin JE, et al., Allopurinol Neurocardiac Protection Trial in Infants Undergoing Heart Surgery Using Deep Hypothermic Circulatory Arrest Pediatrics 2001 108 61-70 [abstract] [Full-Text] | Review, by A Shahin | | 2002-06-06 | THERAPY | Schiffl H, Lang SM, Fischer R, , Daily hemodialysis and the outcome of acute renal failure N Engl J Med 2002 346:305-10 [abstract] | Review, by X Garcia | | 2002-05-15 | THERAPY | Bernard SA, Gray TW, Buist MD, , Treatment of Comatose Survivors of Out-of-Hospital Cardiac Arrest with Induced Hypothermia N Engl J Med 2002 346:557-63 [abstract] | Review, by M Sehgal | | 2002-05-05 | THERAPY | Gattinoni L, Tognoni G, Pesenti A, et al., Effect of Prone Positioning on the Survival of Patients with Acute Respiratory Failure N Engl J Med 2001 345:568-573 [abstract] | Review, by P Kamat | | 2002-05-05 | THERAPY | Dorian P, Cass D, Schwartz B, et al., Amiodarone as compared with lidocaine for shock-resistant ventricular fibrillation N Engl J Med 2002 346(12):884-90 [abstract] | Review, by J Keates Baleeiro K Meert | | 2002-04-27 | DIAGNOSIS | Wells PS, Anderson DR, Rodger M, , Excluding Pulmonary Embolism at the Bedside without Diagnostic Imaging: Management of Patients with Suspected Pulmonary Embolism Presenting to the Emergency Department by Using a Simple Clinical Model and D-dimer Ann Intern Med 2001 135:98-107 [abstract] [Full-Text] | Review, by D Mackey | | 2002-04-12 | ICU OUTCOMES | Morrison AL, Gillis J, O'Connell AJ, , Quality of life of survivors of pediatric intensive care Pediatric Critical Care Medicine 2002 3:1-5 [abstract] | Review, by K Ventre | | 2002-04-01 | THERAPY | Rivers E, Nguyen B, Havstad S, et al. , Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock N Engl J Med 2001 345:1368-77 [abstract] | Review, by S Thammasitboon M Mcpherson | | 2002-03-26 | HARM | Merrer J, De Jonghe B, Golliot F, , Complications of Femoral and Subclavian Venous Catheterization in Critically Ill Patients: A Randomized Controlled Trial JAMA 2001 286:700-707 [abstract] | Review, by J Foland T Petrillo | | 2002-03-23 | PROGNOSIS | Parra DA, Totapally BR, Zahn E, , Outcome of cardiopulmonary resuscitation in a pediatric cardiac intensive care unit Crit Care Med 2000 28(9):296-300 [abstract] | Review, by KP Mistry | | 2002-03-22 | THERAPY | Hilbert G, Gruson D, Vargas F , , Noninvasive ventilation in immunosuppressed patients with pulmonary infiltrates, fever, and acute respiratory failure N Engl J Med 2001 344(7):481-7 [abstract] | Review, by J Barron | | 2002-03-14 | PREDICTION TOOL | Tilford JM, Simpson PM, Yeh TS, , Variation in therapy and outcome for pediatric head trauma patients Crit Care Med 2001 29:1056-1061 [abstract] | Review, by L Faberowski | | 2002-03-08 | PREDICTION TOOL | Haydel MJ, Preston CA, Mills TJ, , Indications for computed tomography in patients with minor head injury N Engl J Med 2000 343:100-5 [abstract] | Review, by M Sehgal MM Mariscalco | | 2002-03-02 | THERAPY | Van den Berghe G, Wouter P, Weeker F, , Intensive Insulin Therapy in Critically Ill Patients N Engl J Med 2001 345:1359-67 [abstract] | Review, by N Hoover A Vats | | 2002-02-22 | PREDICTION TOOL | Cantais E, Paut O, Giorgi R , , Evaluating the prognosis of multiple, severely traumatized children in the intensive care unit Intensive Care Med 2001 27: 1511-1517; DOI 10.1007/s001340101039 [abstract] | Review, by A Torres | | 2002-02-13 | THERAPY | Putensen C, Zech S, Wrigge H , , Long-Term Effects of Spontaneous Breathing During Ventilatory Support in Patients with Acute Lung Injury Am J Respir Crit Care Me 2001 27: 1511-1517; DOI 10.1007/s001340101039 [abstract] | Review, by S Kache V Kesavulu | | 2001-12-20 | THERAPY | Bernard GR, Vincent JL, Laterre PF, , Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis N Engl J Med 2001 344:699-709 [abstract] [Full-Text] | Review, by D Vaughn | | 2001-12-17 | SYSTEMATIC REVIEW | Kellum JA, M Decker J, , , Use of dopamine in acute renal failure: a meta-analysis Crit Care Med 2001 1526-31 [abstract] | Review, by C Davison | | 2001-12-13 | SURROGATE/THERAPY | Ream RS, Loftis LL, Albers GM, , Efficacy of IV Theophylline in Children With Severe Status Asthmaticus Chest 2001 119:1480-1488 [abstract] [Full-Text] | Review, by M Chavolla | | 2001-11-22 | DIAGNOSIS | Hoffman JR, Mower WR, Wolfson AB, Todd KH, Zucker MI Validity of a Set of Clinical Criteria to Rule Out Injury to the Cervical Spine in Patients with Blunt Trauma N Engl J Med 2000 ul 13;343(2):94-99 [abstract] | Review, by A Torres | | 2001-11-13 | SURROGATE/THERAPY | Weber JE, Chudnofsky CR, Younger JG, et al., A randomized comparison of helium-oxygen mixture (heliox) and racemic epinephrine for the treatment of moderate to severe croup Pediatrics 2001 Jun;107(6):E96 [abstract] [Full-Text] | Review, by M Cooper | | 2001-11-11 | SURROGATE/THERAPY | Morris K, Beghetti M, Petros A, Adatia I, Bohn D Comparison of hyperventilation and inhaled nitric oxide for pulmonary hypertension after repair of congenital heart disease Crit Care Med 2000 28(8):2974-8 [abstract] | Review, by R Rao | | 2001-10-31 | SURROGATE | Ranieri VM, Suter PM, Tortorella C, et al. Effect of Mechanical Ventilation on Inflammatory Mediators in Patients with Acute Respiratory Distress Syndrome: A Randomized Controlled Trial JAMA 1999 282:54-61 [abstract] [Full-Text] | Review, by S Kache, R Harrison | | 2001-09-21 | SYSTEMATIC REVIEW | Ostermann ME, Keenan SP, Seiferling RA, Sibbald WJ Sedation in the Intensive Care Unit. A Systematic Review JAMA 2000 283:1451-1459 [abstract] [Full-Text] | Review, by P Jines | | 2001-09-08 | THERAPY | Clifton GL, Miller ER, Choi SC, , Lack of Effect of Induction of Hypothermia after Acute Brain Injury N Engl J Med 2001 344:556-63 [abstract] | Review, by P Prabhakaran | | 2001-08-25 | PREDICTION TOOL | Greenes DS, Schutzman SA., , , Clinical Indicators of Intracranial Injury in Head-injured Infants Pediatrics 1999 104: 861-867 [abstract] [Full-Text] | Review, by P Tandon S Bateman | | 2001-08-18 | DIAGNOSTIC TECH | Tibby SM, Hatherill M, Durward A, Murdoch IA, Are transoesophageal Doppler parameters a reliable guide to paediatric haemodynamic status and fluid management? Intensive Care Med 2001 27:201-205 [abstract] | Review, by M Duthie O Bagshaw | | 2001-08-09 | PREDICTION TOOL | Hatherill M, McIntyre AG, Wattie M, Murdoch IA, Early hyperlactataemia in critically ill children Intensive Care Med 2000 26:314-318 [abstract] | Review, by R Graham | | 2001-08-03 | THERAPY | Tibby SM, Hatherill M, Wright SM, , Exogenous Surfactant Supplementation in Infants with Respiratory Syncytial Virus Bronchiolitis Am J Respir Crit Care Me 2000 162: 1251-1256 [abstract] [Full-Text] | Review, by S Kache | | 2001-07-26 | DIAGNOSTIC TECH | Coule LW, Truemper EJ, Steinhart CM, Lutin WA, Accuracy and utility of a continuous intra-arterial blood gas monitoring system in pediatric patients Crit Care Med 2001 29(2):420-6 [abstract] | Review, by J Tuladhar | | 2001-07-23 | THERAPY | Ciarallo L, Brousseau D, Reinert S, , Higher-Dose Intravenous Magnesium Therapy for Children With Moderate to Severe Acute Asthma Arch Pediatr Adolesc Med 2000 154:979-983 [abstract] [Full-Text] | Review, by M Chavolla | | 2001-07-20 | DIAGNOSTIC TEST | Labenne M, Poyart C, Rambaud C, , Blind protected specimen brush and bronchoalveolar lavage in ventilated children Crit Care Med 1999 1999 ;27:2537-43 [abstract] | Review, by R Sanders AL Graciano | | 2001-07-19 | PREDICTION TOOL | Martin C, Viviand X, Leone M, Thirion X, Effect of norepinephrine on the outcome of septic shock Crit Care Med 2000 28(8):2758-65 [abstract] | Review, by P. Prabhakaran | | 2001-07-13 | THERAPY | Bellomo R, Chapman M, Finfer S, Australian and New Zealand Intensive Care Society (ANZICS) Clinical Trials Group, Low-dose dopamine in patients with early renal dysfunction: a placebo-controlled randomised trial Lancet 2000 356(9248):2139-43 [abstract] | Review, by J Barron A Madikians | | 2001-07-05 | THERAPY | Arnold JH, Hanson JH, Toro-Figuero LO, , Prospective, randomized comparison of high-frequency oscillatory ventilation and conventional mechanical ventilation in pediatric respiratory failure Crit Care Med 1994 22(10):1530-9 [abstract] | Review, by X Garcia | | 2001-07-03 | DIAGNOSTIC TEST | Kress JP, O'Connor MF, Schmidt GA, , Clinical Examination Reliably Detects Intrinsic Positive End-Expiratory Pressure in Critically Ill, Mechanically Ventilated Patients Am J Respir Crit Care Me 1999 159: 290-294 [abstract] | Review, by R. Orellana M. McPherson | | 2001-06-23 | THERAPY | Brent J, McMartin K, Phillips S, Aaron C, Kulig K Fomepizole for the Treatment of Methanol Poisoning N Engl J Med 2001 344:424-9 [abstract] | Review, by D. Mackey | | 2001-06-07 | SURROGATE/THERAPY | Kornecki A, Frndova H, , Coates AL, Shemie SD A Randomized Trial of Prolonged Prone Positioning in Children With Acute Respiratory Failure. Chest 2001 119: 211-218 [abstract] [Full-Text] | Review, by L. Wise-Faberowski | | 2001-05-30 | SURROGATE | López-Herce J, de Lucas N, Carrillo A, Bustinza A, Moral R. Surfactant treatment for acute respiratory distress syndrome Arch Dis Child 1999 80:248-252 [abstract] | Review, by J. Barron, A. Madikians | | 2001-05-30 | SYSTEMATIC REVIEW | Messori A, Trippoli S, Vaiani M, Gorini M, Corrado A. Bleeding and pneumonia in intensive care patients given ranitidine and sucralfate for prevention of stress ulcer: meta-analysis of randomised controlled trials Br Med J 1999 321:1103-1106 [abstract] [Full-Text] | Review, by S Cray | | 2001-05-23 | THERAPY | Lahat E, Goldman M, Barr J, et al., Comparison of intranasal midazolam with intravenous diazepam for treating febrile seizures in children: prospective randomised study Br Med J 2000 321:83-86 [Full-Text] | Review, by A Torres | | 2001-05-22 | THERAPY/PREVENTION | Wathen JE, Roback MG, Mackenzie T, Bothner JP, Does midazolam alter the clinical effects of intravenous ketamine sedation in children? A double-blind, randomized, controlled, emergency department trial Ann Emerg Med 2000 36(6):579-588 [abstract] | Review, by J Haizlip | | 2001-05-04 | HARM | Glaser N, Barnett P, McCaslin I, et al., Risk Factors for Cerebral Edema in Children with Diabetic Ketoacidosis N Engl J Med 2001 344:264-9 [abstract] | Review, by R Rao M Scanlon | | 2001-04-18 | ICU OUTCOMES | Tilford JM, Simpson PM, Green JW, Lensing S, Fiser DH Volume-Outcome Relationships in Pediatric Intensive Care Units Pediatrics 2000 106(2):289-294 [abstract] | Review, by J White | | 2001-04-12 | PREDICTION TOOL | Manczur TI, Greenough A, Pryor D, Rafferty GF, Comparison of predictors of extubation from mechanical ventilation in children. Pediatric Critical Care Medicine 2000 1:28-32 | Review, by S Venkataraman | | 2001-03-04 | SURROGATE/THERAPY | Robertson CS, Valadka AB, Hannay HJ, , Prevention of secondary ischemic insults after severe head injury Crit Care Med 1999 27:2086-95 [abstract] | Review, by JRM White | | 2001-02-23 | HARM | Wong CS, Jelacic S, Habeeb RL, Watkins SL, Tarr PI The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 infections N Engl J Med 2000 342(26):1930-6 [abstract] | Review, by M. Cooper | | 2001-02-16 | THERAPY | Schuh S, Reisman J, Alshehri M, Annie Dupuis, Mary Corey A comparison of inhaled fluticasone and oral prednisone for children with severe acute asthma. N Engl J Med 2000 343(10):689-94 [abstract] | Review, by A. Torres | | 2001-02-06 | QUALITY | Sheridan RL, Hinson MI, Liang MH, , Long-term Outcome of Children Surviving Massive Burns JAMA 2000 283:69-73 [abstract] [Full-Text] | Review, by R Graham | | 2001-01-15 | THERAPY | Miller OI, Tang SF, Keech A, , Inhaled nitric oxide and prevention of pulmonary hypertension after congenital heart surgery: a randomised double-blind study Lancet 2000 356:1464-1469 [abstract] | Review, by K Daphtary K Meert | | 2001-01-05 | SURROGATE END POINT | Corwin HL, Gettinger A, Rodriguez RM, , Efficacy of recombinant human erythropoietin in the critically ill patient: a randomized, double-blind, placebo-controlled trial. Crit Care Med 1999 27:2346-50 [abstract] | Review, by Prasad | | 2001-01-02 | THERAPY | Roosevelt G, Sheehan K, Grupp-Phelan J, , Dexamethasone in bronchiolitis: a randomised controlled trial. Lancet 1996 348:292-5 [abstract] | Review, by E. Stiles | | 2000-12-24 | THERAPY | B?low SM, Nir M, Levin E, , Prednisolone Treatment of Respiratory Syncytial Virus Infection: A Randomized Controlled Trial of 147 Infants. Pediatrics 1999 104: e77 [abstract] [Full-Text] | Review, by J. Hageman B. Markovitz | | 2000-12-21 | PREDICTION TOOL | Venkataraman ST, Khan N, Brown A, , Validation of predictors of extubation success and failure in mechanically ventilated infants and children. Crit Care Med 2000 28(8):2991-6 [abstract] | Review, by D. Epstein R. Bart | | 2000-12-20 | THERAPY | Delclaux C, L'Her E, Alberti C, , Treatment of Acute Hypoxemic Nonhypercapnic Respiratory Insufficiency With Continuous Positive Airway Pressure Delivered by a Face Mask: A Randomized Controlled Trial JAMA 2000 284(18):2352-2360 [abstract] [Full-Text] | Review, by C. Davison | | 2000-12-18 | THERAPY/PREVENTION | Douzinas EE, Pitaridis MT, Louris G, , Prevention of infection in multiple trauma patients by high-dose intravenous immunoglobulins. Crit Care Med 2000 28: 8-15 [abstract] | Review, by S. Bateman | | 2000-12-15 | DIAGNOSIS | Hubble CL, Gentile MA, Tripp DS, Craig DM, Meliones JN Deadspace to tidal volume ratio predicts successful extubation in infants and children. Crit Care Med 2000 28(6):2034-40 [abstract] | Review, by A. Torres | | 2000-12-06 | THERAPY/PREVENTION | Pierce CM, Wade A, Mok Q, , Heparin-bonded central venous lines reduce thrombotic and infective complications in critically ill children. Intensive Care Med 2000 26:967-972 [abstract] | Review, by J. Barron A. Madikians | | 2000-11-12 | PREDICTION TOOL | Keenan HT, Bratton SL, Martin LD, Crawford SW, Weiss NS Outcome of children who require mechanical ventilatory support after bone marrow transplantation. Crit Care Med 2000 28(3):830-5 [abstract] | Review, by X. Garcia H. Tcharmtchi | | 2000-10-27 | PREDICTION TOOL | Baumeister BL, el-Khatib M, Smith PG, Blumer JL, Evaluation of predictors of weaning from mechanical ventilation in pediatric patients. Pediatr Pulmonol 1997 24:344-52 [abstract] | Review, by S. Venkataraman | | 2000-10-20 | PROGNOSIS | Rossi R, Shemie SD, Calderwood S, , Prognosis of pediatric bone marrow transplant recipients requiring mechanical ventilation. Crit Care Med 1999 27:1181-6 [abstract] | Review, by J. Heggen J. Fortenberry | | 2000-10-13 | THERAPY | Brower RG, Shanholtz CB, Fessler HE, , Prospective, randomized, controlled clinical trial comparing traditional versus reduced tidal volume ventilation in acute respiratory distress syndrome patients. Crit Care Med 1999 27:1492-8 [abstract] | Review, by P. Prabhakaran | | 2000-10-07 | THERAPY | Levin M, Quint PA, Goldstein B, , Recombinant bactericidal/permeability-increasing protein (rBPI21) as adjunctive treatment for children with severe meningococcal sepsis: a randomised trial. Lancet 2000 356: 961 - 967 [abstract] | Review, by S. Cray | | 2000-10-07 | THERAPY | Pittet D, Harbarth S, Suter PM, , Impact of immunomodulating therapy on morbidity in patients with severe sepsis. Am J Respir Crit Care Me 1999 160:852-7 [abstract] [Full-Text] | Review, by N. Cvijanovich | | 2000-09-25 | SYS-REVIEW | Garrison MM, Christakis DA, Harvey E, Cummings P, Davis RL. Systemic Corticosteroids in Infant Bronchiolitis: A Meta-analysis Pediatrics 2000 105:e44 [abstract] [Full-Text] | Review, by M. Bonnie Dutta | | 2000-09-22 | SURROGATE/THERAPY | Varpula T, Pettila, Rintala E, Takkunen O, Valtonen Late steroid therapy in primary acute lung injury. Intensive Care Med 2000 26:526-531 [abstract] | Review, by Narsinghani U. Heulitt M. | | 2000-09-21 | PREDICTION TOOL | Farias JA, Alia I, Esteban A, Golubicki, Olazarri FA Weaning from mechanical ventilation in pediatric intensive care patients. Intensive Care Med 1998 24: 1070-1075 [abstract] | Review, by P. Jines A. Madikians | | 2000-09-17 | PREDICTION TOOL | Annane D, S?bille V, Troch? G, , A 3-Level Prognostic Classification in Septic Shock Based on Cortisol Levels and Cortisol Response to Corticotropin. JAMA 2000 283:1038-1045 [abstract] [Full-Text] | Review, by X. Garcia M. McPherson | | 2000-09-10 | THERAPY | Gausche M, Lewis RJ, Stratton SJ, , Effect of Out-of-Hospital Pediatric Endotracheal Intubation on Survival and Neurological Outcome: A Controlled Clinical Trial. JAMA 2000 283:783-790 [abstract] [Full-Text] | Review, by J. Gregory K. Tegtmeyer | | 2000-09-08 | DECISION ANALYSIS | Veenstra DL, Saint S, Sullivan SD, , Cost-effectiveness of antiseptic-impregnated central venous catheters for the prevention of catheter-related bloodstream infection. JAMA 1999 282:554-60 [abstract] [Full-Text] | Review, by M. K. Moynihan Hardart | | 2000-09-01 | THERAPY | Kress JP, Pohlman AS, O'Connor MF, Hall JB, Daily Interruption of Sedative Infusions in Critically Ill Patients Undergoing Mechanical Ventilation N Engl J Med 2000 342:1471-1477 [abstract] | Review, by A. Torres | | 2000-08-21 | SYSTEMATIC REVIEW | Veenstra DL, Saint S, Somnath S, Lumley T, Sullivan SD Efficacy of antiseptic-impregnated central venous catheters in preventing catheter-related bloodstream infection. A meta-analysis. JAMA 1999 281:261-267 [abstract] [Full-Text] | Review, by M. K. Moynihan Hardart | | 2000-08-04 | THERAPY | Alia I, Esteban A, Gordo F, , A randomized and controlled trial of the effect of treatment aimed at maximizing oxygen delivery in patients with severe sepsis or septic shock Chest 1999 28(4):921-8 [abstract] | Review, by Prabhakaran P. Butler T. | | 2000-07-27 | SURROGATE/THERAPY | Ichai C, Soubielle J, Carles M, Giunti C, Grimaud D Comparison of the renal effects of low to high doses of dopamine and dobutamine in critically ill patients: a single-blind randomized study. Crit Care Med 2000 283:235-241 [abstract] [Full-Text] | Review, by Narsinghani U. | | 2000-07-22 | THERAPY | Antonelli M, Conti G, Bufi M, et al. Noninvasive Ventilation for Treatment of Acute Respiratory Failure in Patients Undergoing Solid Organ Transplantation; A Randomized Trial. JAMA 2000 27:2799-805 [abstract] | Review, by P. Prabhakaran, M. Mariscalco | | 2000-06-30 | SYSTEMATIC REVIEW | Beale RJ, Bryg DJ, Bihari DJ, , Immunonutrition in the critically ill: a systematic review of clinical outcome. Crit Care Med 1999 27:2786-91 [abstract] | Review, by Azzam Maha | | 2000-06-02 | THERAPY | Lieh-Lai MW, Kauffman RE, Uy HG, Danjin M, Simpson PM. A randomized comparison of ketorolac tromethamine and morphine for postoperative analgesia in critically ill children. Crit Care Med 1999 27:2782-5 [abstract] | Review, by J. Tuladhar | | 2000-05-09 | SURROGATE END POINT | Pretzlaff RK, Vardis RJ, Pollack MM, , Aminophylline in the treatment of fluid overload. Crit Care Med 1999 342: 1301-1308 [abstract] | Review, by P Jines R Harrison | | 2000-04-28 | THERAPY | Acute Respiratory Distress Syndrome Network, , , , Ventilation with Lower Tidal Volumes as Compared with Traditional Tidal Volumes for Acute Lung Injury and the Acute Respiratory Distress Syndrome. N Engl J Med 2000 27:2331-6 [abstract] | Review, by Steven Cray | | 2000-04-14 | SYSTEMATIC REVIEW | Butler R, Keenan SP, Inman KJ, Sibbald WJ, Block G. Is there a preferred technique for weaning the difficult-to-wean patient? A systematic review of the literature. Crit Care Med 1999 319:595-600 [abstract] [Full-Text] | Review, by A. Torres J. Wohrley | | 2000-04-03 | SYSTEMATIC REVIEW | Ausejo M, Saenz, Pham, , The effectiveness of glucocorticoids in treating croup: meta-analysis. Br Med J 1999 8:491-9 [abstract] | Review, by Melchor Sanchez-Mendiola | | 2000-03-02 | HARM | Bray RJ, , , , Propofol infusion syndrome in children Paed Anaesth 1998 160:829-34 [abstract] [Full-Text] | Review, by Steven Cray | | 2000-02-08 | THERAPY | Guerguerian AM, Gauthier M, Lebel MH, Farrell CA, Lacroix J Ribavirin in ventilated respiratory syncytial virus bronchiolitis. A randomized, placebo-controlled trial. Am J Respir Crit Care Me 1999 27:2096-104 [abstract] | Review, by P. Chalikonda MD | | 2000-02-04 | THERAPY | Reeves JH, Butt WW, Shann F, , Continuous plasmafiltration in sepsis syndrome. Plasmafiltration in Sepsis Study Group. Crit Care Med 1999 20:17-21 [abstract] | Review, by Steven Cray | | 2000-02-02 | THERAPY | Singh NC, Kissoon N, Mofada SA, Bennett M, Bohn DJ Comparison of continuous versus intermittent furosemide administration in postoperative pediatric cardiac patients Crit Care Med 1992 27:1974-81 [abstract] | Review, by Patricia Jines Jonathan D. Feldman | | 2000-01-25 | PROGNOSIS | Khongphatthanayothin A, Wong PC, Samara Y, , Impact of respiratory syncytial virus infection on surgery for congenital heart disease: postoperative course and outcome. Crit Care Med 1999 80: 163-166 [abstract] [Full-Text] | Review, by Christopher J. Babbitt MD Jonathan D. Feldman MD | | 2000-01-14 | DIAGNOSIS | Tibby SM, Hatherill M, Murdoch IA, , Capillary refill and core-peripheral temperature gap as indicators of Hemodynamics status in paediatric intensive care patients Arch Dis Child 1999 109: 1302-1312 [abstract] | Review, by Cray, Steven | | 1999-12-18 | SURROGATE/THERAPY | Barton P, Garcia J, Kouatli A, Kitchen L, Zorka A Hemodynamic effects of i.v. milrinone lactate in pediatric patients with septic shock. A prospective, double-blinded, randomized, placebo-controlled, interventional study. Chest 1996 27:723-32 [abstract] | Review, by Michael Verive, MD | | 1999-12-11 | SURROGATE/THERAPY | Briegel J, Forst H, Haller M, , Stress doses of hydrocortisone reverse hyperdynamic septic shock: a prospective, randomized, double-blind, single-center study. Crit Care Med 1999 27:1409-20 [abstract] | Review, by Vaughan David | | 1999-12-04 | SURROGATE/THERAPY | Enteral Nutrition in ARDS Study Group., Gadek JE, DeMichele SJ, Karlstad MD, Effect of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in patients with acute respiratory distress syndrome Crit Care Med 1999 27:989-96 [abstract] | Review, by Scot Bateman MD, | | 1999-11-18 | THERAPY | Ream RS, Hauver JF, Lynch RE, Kountzman B, Gale GB Low-dose inhaled nitric oxide improves the oxygenation and ventilation of infants and children with acute, hypoxemic respiratory failure Crit Care Med 1999 158: 1831-1838 [abstract] [Full-Text] | Review, by Ron Sanders Jr., MD | | 1999-11-12 | THERAPY/PREVENTION | Darouiche RO, Raad II, Heard SO, , A comparison of two antimicrobial-impregnated central venous catheters. N Engl J Med 1999 158:1770-1777 [abstract] [Full-Text] | Review, by Stephen Schexnayder MD | | 1999-11-11 | SURROGATE END POINT | Gallart L, Lu Q, Puybasset L, , Intravenous Almitrine Combined with Inhaled Nitric Oxide for Acute Respiratory Distress Syndrome Am J Respir Crit Care Me 1998 27:807-14 [abstract] | Review, by Steven Cray | | 1999-11-02 | THERAPY | Lauterbach R, Pawlik D, Kowalczych D, , Effect of the immunomodulating agent, pentoxifylline, in the treatment of sepsis in prematurely delivered infants: a placebo-controlled, double-blind trial Crit Care Med 1999 26:1977-85 [abstract] | Review, by Troy Dominguez MD, | | 1999-10-02 | THERAPY | Jolliet P, Bulpa P , Chevrolet JC, , Effects of the prone position on gas exchange and hemodynamics in severe acute respiratory distress syndrome. Crit Care Med 1998 99:e11 [abstract] [Full-Text] | Review, by Varsha Gharpure, MD Kathleen Meert, MD | | 1999-09-28 | PREDICTION TOOL | Quayle KS, Jaffe DM, Juppermann N, Kaufman BA, Lee BC Diagnostic Testing for Acute Head Injury in Children: When are Head Computed Tomography and Skull Radiographs Indicated? Pediatrics 1997 340:409-417 [abstract] | Review, by Sahhar, Hanna | | 1999-09-12 | THERAPY | Hebert PC, Wells G, Blajchman MA, Marshall J, A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. N Engl J Med 1999 27:200-10 [abstract] | Review, by Fiona H. Levy MD, Barry Markovitz MD, | | 1999-08-23 | SYSTEMATIC REVIEW | Choi PT, Yip G, Quinonez LG, Cook DJ, Crystalloids vs. colloids in fluid resuscitation: a systematic review. Crit Care Med 1999 134:406-412 [abstract] | Review, by Melchor Sanchez-Mendiola, | | 1999-08-23 | THERAPY | Dobyns EL, Cornfield DN, Anas NG, Fortenberry JD, Tasker RC Multicenter randomized controlled trial of the effects of inhaled nitric oxide on gas exchange in children with acute hypoxemic respiratory failure. J Pediatr 1999 159: 695-701 [abstract] | Review, by Al Torres, MD, MS, | | 1999-08-23 | SURROGATE/THERAPY | Dobyns EL, Cornfield DN, Anas NG, Fortenberry JD, Tasker RC Multicenter randomized controlled trial of the effects of inhaled nitric oxide therapy on gas exchange in children with acute hypoxemic respiratory failure. J Pediatr 1999 79: 405-410 [abstract] | Review, by Faberowski L. | | 1999-07-09 | THERAPY | Holzapfel L, Chastang C, Demingeon G, , A randomized study assessing the systematic search for maxillary sinusitis in nasotracheally mechanically ventilated patients. Influence of nosocomial maxillary sinusitis on the occurrence of ventilator-associated pneumonia Am J Respir Crit Care Me 1999 26:645-650 [abstract] | Review, by Kshama Daphtary, MD Kathleen Meert, MD | | 1999-07-02 | THERAPY | Yung M, South M, , , Randomized controlled trial of aminophylline for severe acute asthma. Arch Dis Child 1998 336: 597-604 [abstract] | Review, by Girish Deshpande, MD Kathleen Meert, MD | | 1999-06-27 | THERAPY | Bollaert PE, Charpentier C, Levy B, Debouverie M, Audibert G Reversal of late septic shock with supraphysiologic doses of hydrocortisone. Crit Care Med 1998 26:645-650 [abstract] | Review, by Al Torres, MD, MS, | | 1999-06-27 | THERAPY/PREVENTION | Brochard L, Roudot-Thoraval F, Roupie E, , Tidal Volume Reduction for Prevention of Ventilator-induced Lung Injury in Acute Respiratory Distress Syndrome. Am J Respir Crit Care Me 1998 150: 1166-1172 [abstract] | Review, by Graham Tse, MD, | | 1999-06-19 | THERAPY | The Neonatal Inhaled Nitric Oxide Group , , , , Inhaled nitric oxide in full term and nearly full term infants with hypoxic respiratory failure. N Engl J Med 1997 1731-1736 [abstract] | Review, by P. Chhangani, MD J. Hupert, MD | | 1999-06-18 | SYSTEMATIC REVIEW | Kellner JD, Ohlsson A, Gadomski AM, Wang EE, Efficacy of Bronchodilator Therapy in Bronchiolitis: A Meta-analysis Arch Pediatr Adolesc Med 1996 23:1294-303 [abstract] | Review, by Margarita Reloza-Macias, MD, | | 1999-06-12 | THERAPY | Hollman G, Shen G, Zeng L, , Helium-oxygen improves Clinical Asthma Scores in children with acute bronchiolitis Crit Care Med 1998 280:159-165 [abstract] | Review, by Kate G. Ackerman, M.D., | | 1999-06-11 | SYSTEMATIC REVIEW | Lefering R, Neugebauer E, , , Steroid controversy in sepsis and septic shock: A meta-analysis. Crit Care Med 1995 27:188-95 [abstract] | Review, by Cheri Landers, MD, | | 1999-06-11 | THERAPY | Meduri GU, Headley AS, Golden E, Carson SJ, Umberger RA Effect of prolonged methylprednisolone therapy in unresolving acute respiratory distress syndrome: a randomized controlled trial JAMA 1998 317: 235-240 [Full-Text] | Review, by MIcheal Kelly MD Steven Pon, MD | | 1999-06-11 | THERAPY | Willson DF, Zaritsky A, Bauman LA, , Instillation of calf lung surfactant extract (calfactant) is beneficial in pediatric acute hypoxemic respiratory failure Crit Care Med 1999 316: 961-5 [abstract] | Review, by Poyyapakkam Srivaths M.D. Kathleen Meert, M.D. | | 1999-05-23 | SYSTEMATIC REVIEW | Cochrane Injuries Group Albumin Reviewers., , , , Human albumin administration in critically ill patients: systematic review of randomized controlled trials. Br Med J 1998 150:942-947 [abstract] | Review, by Al Torres, MD, MS | | 1999-04-19 | SYSTEMATIC REVIEW | Randolph AG, Wang EE, , , Ribavirin for Respiratory Syncytial Virus Lower Respiratory Tract Infection: A Systematic Overview Arch Pediatr Adolesc Med 1996 158: 908-916 [abstract] [Full-Text] | Review, by Michael J. Verive, MD | | 1999-04-19 | SYSTEMATIC REVIEW | Schierhout G, Roberts I, , , Fluid resuscitation with colloid or crystalloid solutions in critically ill patients: a systematic review of randomized trials Br Med J 1998 26: 1265-1270 [abstract] | Review, by Michael J. Verive, MD | | 1999-03-09 | THERAPY | Simma B, Burger R, Falk M, Sacher P , Fanconi S A prospective, randomized, and controlled study of fluid management in children with severe head injury: lactated Ringer's solution versus hypertonic saline Crit Care Med 1998 157: 1483-1488 [abstract] [Full-Text] | Review, by Stephanie Sudikoff, MD | | 1999-03-05 | THERAPY | Sanchez Garcia MS, Cambronero Galache JA, Diaz JL, , Effectiveness and Cost of Selective Decontamination of the Digestive Tract in Critically Ill Intubated Patients. A randomized, double-blind, placebo-controlled, multicenter trial Am J Respir Crit Care Me 1998 130:191-6 [abstract] | Review, by Paulette Johnson, MD Barry Markovitz, MD | | 1999-03-04 | THERAPY | Troncy E, Collet JP, Shapiro S, Guimond JG, Blair L Inhaled Nitric Oxide in Acute Respiratory Distress Syndrome: A Pilot Randomized Controlled Study. Am J Respir Crit Care Me 1998 339: 1030-35 [abstract] | Review, by Maher Eldadah MD | | 1999-03-03 | THERAPY | Klassen TP, Sutcliffe TS, Watters LK, Wells Ga, Allen UD Dexamethasone in salbutamol-treated inpatients with acute bronchiolitis: A randomized, controlled trial J Pediatr 1997 23: 1430-1439 [abstract] | Review, by Barry Markovitz, MD, | | 1999-01-21 | THERAPY | Qureshi F, Pestian J, Davis P, Zaritsky A, Effect of nebulized ipratropium bromide on the hospitalization rates of children with asthma. N Engl J Med 1998 26:1164-1172 [abstract] | Review, by Al Torres, MD, MS G. Kris Bysani, MD | | 1999-01-17 | SYSTEMATIC REVIEW | Cronin L, Cook DJ, Carlet J, Heyland DK, King D Corticosteroids treatment for sepsis: a critical appraisal and meta-analysis of the literature Crit Care Med 1995 338: 347-354 [abstract] | Review, by Varsha Gharpure, MD Kathleen Meert, MD, | | 1998-12-24 | THERAPY | Atkinson S, Sieffert E, Bihari D, GuyŐ Hospital Intensive Care Group, A prospective, randomized, double-blind, controlled clinical trial of enteral immunonutrition in the critically ill Crit Care Med 1998 2:651-656 [abstract] | Review, by Tom Brazelton, MD, MPH, | | 1998-12-14 | THERAPY/PREVENTION | Amato MBP, Barbas CSV, Medeiros DM, , Effect of a Protective-Ventilation Strategy on Mortality in the Acute Respiratory Distress Syndrome. N Engl J Med 1998 101: 361-368 [abstract] | Review, by Kazuo Obata MD | | 1998-11-23 | SYSTEMATIC REVIEW | Osmond MH, Klassen TP, , , Efficacy of ipratropium bromide in acute childhood asthma: a meta-analysis Acad Emergency Med 1995 339:429-435 [abstract] | Review, by Al Torres, MD, MS | | 1998-11-19 | THERAPY | Dobson JV, Stephen-Groff SM, McMahon SR, Stemmler, Brallier SL The Use of Albuterol in Hospitalized Infants With Bronchiolitis Pediatrics 1998 52: 634-637 [abstract] | Review, by Kshama Daphtary, MD Kathleen Meert, MD, | | 1998-10-06 | THERAPY | Antonelli M, Conti G,, Rocco M, , Bufi M, De Blasi RA A comparison of noninvasive positive-pressure ventilation and conventional mechanical ventilation in patients with acute respiratory failure. N Engl J Med 1998 157: 1372-1380 [abstract] [Full-Text] | Review, by Girish Deshpande, MD Kathleen Meert, MD | | 1998-09-29 | THERAPY | van Woensel JB, Wolfs TF, van Aalderen WM, Brand PL, Kimpen JL Randomized double blind placebo controlled trial of prednisolone in children admitted to hospital with respiratory syncytial virus bronchiolitis Thorax 1997 15:579-583 [abstract] | Review, by Al Torres, M.D., M.S. | | 1998-09-04 | THERAPY | Micheal JR, Barton RG, Saffle JR, , Inhaled Nitric Oxide Versus Conventional Therapy: Effect on Oxygenation in ARDS Am J Respir Crit Care Me 1998 338: 355-361 [abstract] | Review, by Gerardo Reyes, M.D. | | 1998-08-19 | THERAPY | Slusher T, Gbadero D, Howard C, Lewison L, Giroir B Randomized, placebo-controlled, double blinded trial of dexamethasone in African children with sepsis Pediatr Infect Dis J 1996 338: 791-797 [abstract] | Review, by Mignon McCulloch, MD Max Klein, MD | | 1998-08-18 | THERAPY | Stewart TE, Meade MO, Cook DJ, , Evaluation of a Ventilation Strategy to Prevent Barotrauma in Patients at High Risk for Acute Respiratory Distress Syndrome N Engl J Med 1998 26: 15-23 [abstract] | Review, by Mona McPherson MD Michele Mariscalo MD | | 1998-08-06 | THERAPY | Cook D, Guyatt G, Marshall J, , A Comparison of Sucralfate and Ranitidine for the Prevention of Upper Gastrointestinal Bleeding in Patients Requiring Mechanical Ventilation N Engl J Med 1998 25:346-351 [abstract] | Review, by Scot T. Bateman, M.D | | 1998-06-15 | THERAPY | Dellinger RP, Zimmerman JL, Taylor RW, Straube RC, Hauser DL Effects of inhaled nitric oxide in patients with acute respiratory distress syndrome: results of a randomized phase II trial Crit Care Med 1998 127:267-274 [abstract] | Review, by Scot Bateman, MD | | 1998-06-13 | THERAPY | Kuusela AL, Ruuska T, Karikoski R, Laippala P, Ilonen S A randomized controlled study of prophylactic Ranitidine in preventing stress-induced gastric mucosal lesions in neonatal intensive care unit patients. Crit Care Med 1997 127:257-266 [abstract] | Review, by Girish Deshpande, MD Kathleen Meert, MD | | 1998-01-29 | THERAPY | Maki DG, Stolz SM, Wheeler S, , Prevention of Central Venous Catheter-Related Bloodstream Infection by Use of an Antiseptic-Impregnated Catheter. Ann Intern Med 1997 110: 1025-34 [abstract] | Review, by Stephen Schexnayder, | | 1998-01-29 | THERAPY | Raad D, Darouiche ER, Dupuis J, , Central venous catheters coated with minocycline and rifampin for the prevention of catheter-related colonization and bloodstream infections. Ann Intern Med 1997 314:1855-1859 [abstract] | Review, by Stephen Schexnayder | | 1997-09-02 | SYSTEMATIC REVIEW | Alderson P, Roberts I. , , , Corticosteroids in acute traumatic brain injury: Systematic review of randomized controlled trials. Br Med J 1997 314:1855-1859 [abstract] | Review, by Scot Bateman | | 1997-08-25 | THERAPY | Harel Y, Vardi A, Quigley, B rink, Manning SC Extubation failure due to post-extubation stridor is better correlated with neurologic impairment than with upper airway lesions in critically ill pediatric patients Int J Pediatr Otorhynolaryngal 1997 39: 147-158 [abstract] | Review, by Barry P. Markovitz | | 1997-07-29 | DECISION ANALYSIS | Sterling T, Ho EJ, Brehm WT, Kirkpatrick MB, Diagnosis and treatment of ventilator-associated pneumonia--Impact on survival. A decision analysis. Chest 1996 110: 1025-34 [abstract] | Review, by Adrienne Randolph | | 1997-05-27 | THERAPY | Ciarallo, L, Sauer AH, Shannon NW, , Intravenous magnesium therapy for moderate to severe pediatric asthma: Results of a randomized, placebo-controlled trial. J Pediatr 1996 129: 809-14 [abstract] | Review, by Barry Markovitz | | 1997-05-15 | THERAPY | Marion DW, Penrod LE, Kelsey SF, Obrist WD, Kochanek PM Treatment of traumatic brain injury with moderate hypothermia N Engl J Med 1997 336: 540-546 [abstract] | Review, by Barry Markovitz, MD | | 1997-04-20 | THERAPY | Anene O , Meert KL, Uy H, Simpson P, Sarmiak AP Dexamethasone for the prevention of postextubation airway obstruction: a prospective, randomized, double-blind, placebo-controlled trial. Crit Care Med 1996 24: 1666-1669 [abstract] | Review, by Adrienne Randolph | | 1997-04-20 | THERAPY | Tellez DW, Galvis AG, Storgion SA, Amer HN, Hoseyni M Dexamethasone in the prevention of postextubation stridor in children. J Pediatr 1991 118:289-294 [abstract] | Review, by Adrienne Randolph | | 1997-03-17 | PROGNOSIS | Schindler MB, Bohn D, Cox PN, McCrindle BW, Jarvis A Outcome of out-of-hospital cardiac or respiratory arrest in children. N Engl J Med 1996 333:1473-9 [abstract] | Review, by Adrienne Randolph | | 1997-03-17 | THERAPY | UK collaborative randomized trial of neonatal extracorporeal membrane oxygenation. , , , , UK collaborative randomized trial of neonatal extracorporeal membrane oxygenation. Lancet 1996 348: 75-82 [abstract] | Review, by Adrienne Randolph |
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