11 th Annual Pediatric Critical Care Colloquium
Session/Time Pulmonary I/Thu, 9:45 - 12 00 PM
Title A World Wide Web Based Mathematical Model of Pediatric Mechanical Ventilation
Author K Tegtmeyer, MD; J Zier, MD
Affiliation University of Minnesota, Department of Pediatrics, Division of Pulmonary and Critical Care Medicine
Introduction Mechanical Ventilation can be difficult to ]cam, particularly due to ie multitude of interactions between the ventilator settings and me blood gases of a patienl A few investigators interested in the scientific applications have developed mathematical models of mechanical ventilation, however there is no widely available mechanical ventilation simulator on the World Wide Web (Web). Our goal was to develop a Web based Mechanical Ventilation model that would allow residents and other practitioners to experiment with ventilator changes and obseme the effcr-ltson blood gases. This model will enhance their leaming of ventilator management.
Method Ventilator settings, including mode, respiratory rate, ,idal volume, inspiratory time, FiO2 and PEEP, plus physiologic parameters (e.g. compliance, dead space, arteriolar/alveclar ratio) Nere used to develop equations to realistically predict artenai blood gases (pH, pCO2, pO2) and other patient specific information. Patient parameters (e.g. compliance) were altered to develop equations specific to various disease states (such as ARDS). These equations were then written into a Java script ,)rogram for incorporation into an interactive web-based site. The site includes prompts for the user to input individual ventilator settings for several patient scenarios, and allows for each value to n changed repeatedly
Result Blood gas and patient derived values are instantly calculated from changes in the mc>delventilator settings. These values were realistic with a reasonable 'normal' ventilator setting range. Problems with unrealistic values did arise with outlying ventilator settings
Conclusion A mathematical model of mechanical ventilation realistically recreate blood gas reswnses to changes in mechanical ventilator settings. Placement of this model on the World Wide Web will allow more widespread access to our residents and practitioners world wide.

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Document created April 12, 1999