Hypertonic Fluid Administration
Fisher et al. (1992) Journal of Neurosurgical Anesthesiology, 4
- Reduction in mean ICP in children 2 hours after bolus administration of 3% saline
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Taylor et al. (1996) Journal of Pediatric Surgery,31(1)
- ICP is lowered by resuscitation with hypertonic saline vs. lactated ringers solution in an animal model
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Qureshi et al. (1998) Critical Care Medicine, 26(3)
- Reduction in mean ICP within 12 hours of continuous infusion of 3% sadium acetate solution
- Little continued benefit after 72 hours of treatment